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Tz (has ) Tj 51.428571 0 0 51.428571 0 1987.674877 Tm 6.358333 0 Td 46.759259 Tz (certain ) Tj 2.177778 0 Td 45.910494 Tz (rights ) Tj 1.847222 0 Td 43.75 Tz (in ) Tj 0.719444 0 Td 49.691358 Tz (the ) Tj 1.088889 0 Td 47.638889 Tz (invention. ) Tj 38.571429 0 0 38.571429 0 1915 Tm 12.159259 0 Td 112.345679 Tz (BACKGROUND ) Tj 7.025926 0 Td 99.382716 Tz (OF ) Tj 1.4 0 Td 106.584362 Tz (THE ) Tj 2.177778 0 Td 98.902606 Tz (INVENTION ) Tj 51.428571 0 0 51.428571 0 1828.265985 Tm 7.116667 0 Td 55.092593 Tz (Designing ) Tj 3.266667 0 Td 55.740741 Tz (economical ) Tj 3.675 0 Td 48.971193 Tz (synthesis ) Tj 2.975 0 Td 59.953704 Tz (of ) Tj 0.933333 0 Td 59.259259 Tz (complex ) Tj 2.819444 0 Td 56.17284 Tz (nanostruc ) Tj 51.428571 0 0 51.428571 0 1788.268143 Tm 6.338889 0 Td 47.314815 Tz (tures ) Tj 1.691667 0 Td 38.888889 Tz (is ) Tj 0.738889 0 Td 48.881173 Tz (increasingly ) Tj 3.772222 0 Td 52.572016 Tz (important ) Tj 3.091667 0 Td 47.530864 Tz (for ) Tj 1.069444 0 Td 46.450617 Tz (practical ) Tj 2.741667 0 Td 48.881173 Tz (applications ) Tj 3.791667 0 Td 56.712963 Tz (of ) Tj 51.428571 0 0 51.428571 0 1743.993007 Tm 6.358333 0 Td 53.292181 Tz (nanoscale ) Tj 3.033333 0 Td 46.180556 Tz (objects. ) Tj 2.391667 0 Td 51.602564 Tz (Nanoparticles ) Tj 4.180556 0 Td 57.523148 Tz (have ) Tj 1.536111 0 Td 54.282407 Tz (demonstrated ) Tj 4.044444 0 Td 63.194444 Tz (tremen ) Tj 58.571429 0 0 58.571429 0 1704.934545 Tm 5.582927 0 Td 49.796748 Tz (dous ) Tj 1.331707 0 Td 49.593496 Tz (promise ) Tj 2.236585 0 Td 39.837398 Tz (in ) Tj 0.631707 0 Td 57.621951 Tz (many ) Tj 1.536585 0 Td 41.588493 Tz (applications, ) Tj 3.397561 0 Td 46.95122 Tz (such ) Tj 1.297561 0 Td 44.105691 Tz (as ) Tj 0.64878 0 Td 39.061345 Tz (catalysis,' ) Tj 2.782927 0 Td 61.178862 Tz (medi ) Tj 57.142857 0 0 57.142857 0 1662.679245 Tm 5.7225 0 Td 41.805556 Tz (cal ) Tj 0.9625 0 Td 47.395833 Tz (imaging, ) Tj 2.73 0 Td 53.472222 Tz (and ) Tj 1.155 0 Td 50.643939 Tz (development ) Tj 3.5175 0 Td 53.958333 Tz (of ) Tj 0.7525 0 Td 58.333333 Tz (new ) Tj 1.2425 0 Td 42 Tz (analytical ) Tj 2.7475 0 Td 49.21875 Tz (methods. ) Tj 52.857143 0 0 52.857143 0 1620.165829 Tm 6.186486 0 Td 50.702703 Tz (Nanoparticle-phospholipid ) Tj 7.908108 0 Td 50.45045 Tz (hybrids ) Tj 2.459459 0 Td 55.18018 Tz (have ) Tj 1.645946 0 Td 53.603604 Tz (been ) Tj 1.645946 0 Td 54.391892 Tz (used ) Tj 1.645946 0 Td 46.246246 Tz (for ) Tj 1.135135 0 Td 48.873874 Tz (in ) Tj 58.571429 0 0 58.571429 0 1579.617068 Tm 5.565854 0 Td 46.239837 Tz (vivo ) Tj 1.280488 0 Td 50.406504 Tz (imaging ) Tj 2.236585 0 Td 53.116531 Tz (and ) Tj 1.109756 0 Td 49.796748 Tz (drug ) Tj 1.34878 0 Td 40.406504 Tz (delivery.' ) Tj 38.571429 0 0 38.571429 0 1502 Tm 13.092593 0 Td 117.283951 Tz (SUMMARY ) Tj 5.159259 0 Td 101.54321 Tz (OF ) Tj 1.477778 0 Td 105.144033 Tz (THE ) Tj 2.177778 0 Td 97.942387 Tz (INVENTION ) Tj 51.428571 0 0 51.428571 0 1415.687898 Tm 7.097222 0 Td 62.654321 Tz (The ) Tj 1.341667 0 Td 49.691358 Tz (invention ) Tj 2.877778 0 Td 51.446759 Tz (provides ) Tj 2.702778 0 Td 55.092593 Tz (a ) Tj 0.563889 0 Td 51.851852 Tz (metal ) Tj 1.808333 0 Td 49.691358 Tz (nanoparticle ) Tj 3.733333 0 Td 53.652263 Tz (entrapped ) Tj 3.111111 0 Td 51.851852 Tz (or ) Tj 51.428571 0 0 51.428571 0 1374.853081 Tm 6.358333 0 Td 52.391975 Tz (encapsulated ) Tj 3.888889 0 Td 45.37037 Tz (in ) Tj 0.7 0 Td 55.092593 Tz (a ) Tj 0.447222 0 Td 57.87037 Tz (polymer ) Tj 2.566667 0 Td 52.121914 Tz (nanocapsule, ) Tj 3.869444 0 Td 60.493827 Tz (and ) Tj 1.244444 0 Td 59.953704 Tz (method ) Tj 2.294444 0 Td 47.530864 Tz (for ) Tj 0.972222 0 Td 82.098765 Tz (mak ) Tj 51.428571 0 0 51.428571 0 1333.753358 Tm 6.358333 0 Td 50.771605 Tz (ing ) Tj 1.108333 0 Td 59.41358 Tz (and ) Tj 1.225 0 Td 53.148148 Tz (using ) Tj 1.75 0 Td 50.771605 Tz (the ) Tj 1.108333 0 Td 53.148148 Tz (metal ) Tj 1.788889 0 Td 49.96142 Tz (nanoparticle ) Tj 3.733333 0 Td 53.652263 Tz (entrapped ) Tj 3.072222 0 Td 46.990741 Tz (in ) Tj 0.758333 0 Td 55.092593 Tz (a ) Tj 0.505556 0 Td 58.333333 Tz (polymer ) Tj 51.428571 0 0 51.428571 0 1295 Tm 6.358333 0 Td 52.121914 Tz (nanocapsule. ) Tj 51.428571 0 0 51.428571 0 1249.276215 Tm 7.116667 0 Td 46.990741 Tz (In ) Tj 0.758333 0 Td 58.333333 Tz (one ) Tj 1.205556 0 Td 48.148148 Tz (aspect, ) Tj 2.197222 0 Td 50.771605 Tz (the ) Tj 1.108333 0 Td 49.331276 Tz (invention ) Tj 2.838889 0 Td 52.662037 Tz (provides ) Tj 2.702778 0 Td 51.851852 Tz (a ) Tj 0.544444 0 Td 52.5 Tz (metal ) Tj 1.788889 0 Td 49.691358 Tz (nanoparticle ) Tj 51.428571 0 0 51.428571 0 1209.43309 Tm 6.358333 0 Td 53.292181 Tz (entrapped ) Tj 3.052778 0 Td 51.851852 Tz (or ) Tj 0.777778 0 Td 52.391975 Tz (encapsulated ) Tj 3.927778 0 Td 46.990741 Tz (in ) Tj 0.758333 0 Td 55.092593 Tz (a ) Tj 0.486111 0 Td 58.796296 Tz (polymer ) Tj 2.644444 0 Td 51.851852 Tz (nanocapsule. ) Tj 3.966667 0 Td 43.75 Tz (In ) Tj 0.758333 0 Td 60.493827 Tz (cer ) Tj 51.428571 0 0 51.428571 0 1163.781022 Tm 6.338889 0 Td 46.180556 Tz (tain ) Tj 1.263889 0 Td 56.983025 Tz (embodiments, ) Tj 4.297222 0 Td 49.691358 Tz (the ) Tj 1.108333 0 Td 52.5 Tz (metal ) Tj 1.788889 0 Td 49.421296 Tz (nanoparticle ) Tj 3.752778 0 Td 37.268519 Tz (is ) Tj 0.622222 0 Td 58.333333 Tz (a ) Tj 0.544444 0 Td 52.5 Tz (metal ) Tj 1.769444 0 Td 49.421296 Tz (selected ) Tj 51.428571 0 0 51.428571 0 1125.142857 Tm 6.358333 0 Td 58.333333 Tz (from ) Tj 1.555556 0 Td 50.771605 Tz (the ) Tj 1.030556 0 Td 57.037037 Tz (group ) Tj 1.905556 0 Td 48.935185 Tz (consisting ) Tj 3.072222 0 Td 56.712963 Tz (of ) Tj 0.777778 0 Td 41.666667 Tz (silver, ) Tj 1.886111 0 Td 51.131687 Tz (platinum, ) Tj 2.936111 0 Td 51.527778 Tz (palladium, ) Tj 3.247222 0 Td 60.493827 Tz (and ) Tj 51.428571 0 0 51.428571 0 1081.457143 Tm 6.358333 0 Td 47.962963 Tz (gold. ) Tj 1.633333 0 Td 46.990741 Tz (In ) Tj 0.7 0 Td 46.759259 Tz (certain ) Tj 2.1 0 Td 56.712963 Tz (embodiments, ) Tj 4.2 0 Td 50.771605 Tz (the ) Tj 1.05 0 Td 52.5 Tz (metal ) Tj 1.730556 0 Td 49.691358 Tz (nanoparticle ) Tj 3.694444 0 Td 40.509259 Tz (is ) Tj 0.602778 0 Td 41.203704 Tz (silver. ) Tj 51.428571 0 0 51.428571 0 1040.357625 Tm 6.377778 0 Td 48.611111 Tz (In ) Tj 1.05 0 Td 46.296296 Tz (certain ) Tj 2.391667 0 Td 56.983025 Tz (embodiments, ) Tj 4.530556 0 Td 50.771605 Tz (the ) Tj 1.322222 0 Td 58.796296 Tz (polymer ) Tj 2.897222 0 Td 54.208754 Tz (nanocapsule ) Tj 4.005556 0 Td 40.509259 Tz (is ) Tj 0.933333 0 Td 55.092593 Tz (a ) Tj 51.428571 0 0 51.428571 0 1001.336856 Tm 6.358333 0 Td 58.333333 Tz (copolymer ) Tj 3.519444 0 Td 59.953704 Tz (of ) Tj 0.991667 0 Td 51.851852 Tz (a ) Tj 0.777778 0 Td 50 Tz (styrene ) Tj 2.508333 0 Td 51.851852 Tz (with ) Tj 1.672222 0 Td 50.771605 Tz (divinylbenzene. ) Tj 5.016667 0 Td 48.611111 Tz (In ) Tj 0.972222 0 Td 48.611111 Tz (certain ) Tj 51.428571 0 0 51.428571 0 958.680745 Tm 6.358333 0 Td 56.983025 Tz (embodiments, ) Tj 4.355556 0 Td 50.771605 Tz (the ) Tj 1.186111 0 Td 58.333333 Tz (polymer ) Tj 2.722222 0 Td 54.208754 Tz (nanocapsule ) Tj 3.869444 0 Td 37.268519 Tz (is ) Tj 0.719444 0 Td 58.333333 Tz (a ) Tj 0.641667 0 Td 57.973251 Tz (copolymer ) Tj 3.383333 0 Td 56.712963 Tz (of ) Tj 51.428571 0 0 51.428571 0 919.038251 Tm 6.338889 0 Td 47.276688 Tz (tert-butylstyrene ) Tj 4.997222 0 Td 53.472222 Tz (with ) Tj 1.477778 0 Td 50.771605 Tz (divinylbenzene. ) Tj 51.428571 0 0 51.428571 0 873.967908 Tm 7.116667 0 Td 46.990741 Tz (In ) Tj 0.738889 0 Td 52.777778 Tz (another ) Tj 2.352778 0 Td 47.222222 Tz (aspect, ) Tj 2.197222 0 Td 49.691358 Tz (the ) Tj 1.069444 0 Td 50.05144 Tz (invention ) Tj 2.877778 0 Td 51.446759 Tz (provides ) Tj 2.663889 0 Td 55.092593 Tz (a ) Tj 0.544444 0 Td 59.41358 Tz (method ) Tj 2.333333 0 Td 56.712963 Tz (of ) Tj 0.758333 0 Td 64.814815 Tz (pre ) Tj 51.428571 0 0 51.428571 0 835.251256 Tm 6.358333 0 Td 51.851852 Tz (paring ) Tj 2.1 0 Td 55.092593 Tz (a ) Tj 0.602778 0 Td 52.5 Tz (metal ) Tj 1.866667 0 Td 49.421296 Tz (nanoparticle ) Tj 3.791667 0 Td 53.292181 Tz (entrapped ) Tj 3.130556 0 Td 51.851852 Tz (or ) Tj 0.816667 0 Td 52.662037 Tz (encapsulated ) Tj 4.044444 0 Td 43.75 Tz (in ) Tj 0.797222 0 Td 55.092593 Tz (a ) Tj 51.428571 0 0 51.428571 0 794.504142 Tm 6.358333 0 Td 58.333333 Tz (polymer ) Tj 2.663889 0 Td 51.851852 Tz (nanocapsule, ) Tj 3.947222 0 Td 50.771605 Tz (the ) Tj 1.127778 0 Td 59.953704 Tz (method ) Tj 2.372222 0 Td 54.444444 Tz (comprising ) Tj 3.461111 0 Td 54.282407 Tz (polymerizing ) Tj 51.428571 0 0 51.428571 0 749.139623 Tm 6.358333 0 Td 64.00463 Tz (monomers ) Tj 3.344444 0 Td 48.611111 Tz (to ) Tj 0.913889 0 Td 56.712963 Tz (form ) Tj 1.652778 0 Td 51.851852 Tz (the ) Tj 1.205556 0 Td 58.796296 Tz (polymer ) Tj 2.741667 0 Td 54.503367 Tz (nanocapsule ) Tj 3.869444 0 Td 59.41358 Tz (and ) Tj 1.361111 0 Td 56.481481 Tz (simulta ) Tj 51.428571 0 0 51.428571 0 709.236453 Tm 6.358333 0 Td 53.703704 Tz (neously ) Tj 2.488889 0 Td 56.481481 Tz (forming ) Tj 2.566667 0 Td 49.691358 Tz (the ) Tj 1.127778 0 Td 53.148148 Tz (metal ) Tj 1.847222 0 Td 47.863248 Tz (nanoparticle. ) Tj 4.005556 0 Td 46.990741 Tz (In ) Tj 0.797222 0 Td 46.759259 Tz (certain ) Tj 2.216667 0 Td 66.975309 Tz (embodi ) Tj 51.428571 0 0 51.428571 0 665.67658 Tm 6.358333 0 Td 52.932099 Tz (ments, ) Tj 2.177778 0 Td 49.691358 Tz (the ) Tj 1.166667 0 Td 63.599537 Tz (monomers ) Tj 3.305556 0 Td 49.691358 Tz (are ) Tj 1.127778 0 Td 55.681818 Tz (polymerized ) Tj 3.927778 0 Td 52.5 Tz (using ) Tj 1.808333 0 Td 58.333333 Tz (a ) Tj 0.602778 0 Td 46.450617 Tz (free-radical ) Tj 51.428571 0 0 51.428571 0 622.276995 Tm 6.358333 0 Td 40.509259 Tz (initiator. ) Tj 2.586111 0 Td 46.990741 Tz (In ) Tj 0.7 0 Td 46.759259 Tz (certain ) Tj 2.1 0 Td 56.983025 Tz (embodiments, ) Tj 4.2 0 Td 50.771605 Tz (the ) Tj 1.05 0 Td 63.194444 Tz (monomers ) Tj 3.15 0 Td 50.771605 Tz (are ) Tj 1.030556 0 Td 62.962963 Tz (polymer ) Tj 51.428571 0 0 51.428571 0 582.680965 Tm 6.358333 0 Td 51.041667 Tz (ized ) Tj 1.536111 0 Td 46.990741 Tz (in ) Tj 0.894444 0 Td 51.851852 Tz (a ) Tj 0.661111 0 Td 44.722222 Tz (lipid ) Tj 1.633333 0 Td 44.965278 Tz (bilayer. ) Tj 2.527778 0 Td 48.611111 Tz (In ) Tj 0.913889 0 Td 47.222222 Tz (certain ) Tj 2.313889 0 Td 56.983025 Tz (embodiments, ) Tj 4.452778 0 Td 48.611111 Tz (the ) Tj 1.205556 0 Td 45.37037 Tz (lipid ) Tj 51.428571 0 0 51.428571 0 542.403101 Tm 6.338889 0 Td 49.537037 Tz (bilayer ) Tj 2.294444 0 Td 38.888889 Tz (is ) Tj 0.738889 0 Td 51.851852 Tz (a ) Tj 0.563889 0 Td 44.722222 Tz (lipid ) Tj 1.575 0 Td 49.074074 Tz (bilayer ) Tj 2.255556 0 Td 59.953704 Tz (of ) Tj 0.875 0 Td 51.851852 Tz (a ) Tj 0.602778 0 Td 51.851852 Tz (liposome. ) Tj 3.091667 0 Td 46.990741 Tz (In ) Tj 0.816667 0 Td 47.222222 Tz (certain ) Tj 2.255556 0 Td 66.975309 Tz (embodi ) Tj 51.428571 0 0 51.428571 0 500.354839 Tm 6.358333 0 Td 52.932099 Tz (ments, ) Tj 2.041667 0 Td 50.771605 Tz (the ) Tj 1.05 0 Td 60.493827 Tz (method ) Tj 2.313889 0 Td 47.685185 Tz (further ) Tj 2.1 0 Td 54.372428 Tz (comprises ) Tj 3.091667 0 Td 49.691358 Tz (the ) Tj 1.05 0 Td 46.990741 Tz (step ) Tj 1.302778 0 Td 55.092593 Tz (of ) Tj 0.738889 0 Td 57.523148 Tz (removing ) Tj 2.897222 0 Td 49.691358 Tz (the ) Tj 51.428571 0 0 51.428571 0 460.435616 Tm 6.358333 0 Td 44.722222 Tz (lipid ) Tj 1.827778 0 Td 48.611111 Tz (bilayer ) Tj 2.508333 0 Td 45.37037 Tz (after ) Tj 1.808333 0 Td 49.331276 Tz (synthesis ) Tj 3.130556 0 Td 61.574074 Tz (of ) Tj 1.127778 0 Td 49.691358 Tz (the ) Tj 1.4 0 Td 51.851852 Tz (metal ) Tj 2.080556 0 Td 49.96142 Tz (nanoparticle ) Tj 51.428571 0 0 51.428571 0 421.295499 Tm 6.358333 0 Td 53.292181 Tz (entrapped ) Tj 3.052778 0 Td 45.37037 Tz (in ) Tj 0.738889 0 Td 55.092593 Tz (a ) Tj 0.505556 0 Td 58.796296 Tz (polymer ) Tj 2.644444 0 Td 51.58179 Tz (nanocapsule. ) Tj 38.571429 0 0 38.571429 0 343 Tm 10.992593 0 Td 90.740741 Tz (BRIEF ) Tj 3.007407 0 Td 94.668911 Tz (DESCRIPTION ) Tj 6.533333 0 Td 101.54321 Tz (OF ) Tj 1.451852 0 Td 105.144033 Tz (THE ) Tj 2.177778 0 Td 105.864198 Tz (DRAWINGS ) Tj 51.428571 0 0 51.428571 0 253.736021 Tm 7.116667 0 Td 54.282407 Tz (FIG. ) Tj 1.575 0 Td 45.37037 Tz (1 ) Tj 0.563889 0 Td 58.981481 Tz (shows ) Tj 1.963889 0 Td 58.333333 Tz (a ) Tj 0.563889 0 Td 53.20216 Tz (simultaneous ) Tj 4.063889 0 Td 48.971193 Tz (synthesis ) Tj 2.877778 0 Td 56.712963 Tz (of ) Tj 0.797222 0 Td 58.796296 Tz (polymer ) Tj 2.663889 0 Td 68.055556 Tz (nano ) Tj 51.428571 0 0 51.428571 0 214.665857 Tm 6.358333 0 Td 51.041667 Tz (capsules ) Tj 2.702778 0 Td 58.333333 Tz (and ) Tj 1.263889 0 Td 53.292181 Tz (entrapped ) Tj 3.111111 0 Td 45.37037 Tz (silver ) Tj 1.866667 0 Td 47.685185 Tz (nanoparticles. ) Tj 4.297222 0 Td 56.712963 Tz (Both ) Tj 1.594444 0 Td 48.611111 Tz (reactions ) Tj 51.428571 0 0 51.428571 0 171.118859 Tm 6.358333 0 Td 49.691358 Tz (are ) Tj 1.069444 0 Td 44.191919 Tz (facilitated ) Tj 3.091667 0 Td 58.333333 Tz (by ) Tj 0.894444 0 Td 55.092593 Tz (a ) Tj 0.525 0 Td 46.450617 Tz (free-radical ) Tj 3.519444 0 Td 45.37037 Tz (photoinitiator. ) Tj 30 0 0 30 0 2547 Tm 41.666667 0 Td 75 Tz (10 ) Tj 30 0 0 30 0 2339 Tm 41.666667 0 Td 72.222222 Tz (15 ) Tj 30 0 0 30 0 1923 Tm 41.6 0 Td 77.777778 Tz (25 ) Tj 30 0 0 30 0 1716 Tm 41.6 0 Td 80.555556 Tz (30 ) Tj 30 0 0 30 0 1507 Tm 41.6 0 Td 77.777778 Tz (35 ) Tj 30 0 0 30 0 1299 Tm 41.566667 0 Td 83.333333 Tz (40 ) Tj 30 0 0 30 0 1091 Tm 41.566667 0 Td 80.555556 Tz (45 ) Tj 30 0 0 30 0 883 Tm 41.6 0 Td 80.555556 Tz (50 ) Tj 30 0 0 30 0 675 Tm 41.6 0 Td 77.777778 Tz (55 ) Tj 30 0 0 30 0 467 Tm 41.633333 0 Td 77.777778 Tz (60 ) Tj 30 0 0 30 0 259 Tm 41.633333 0 Td 75 Tz (65 ) Tj 51.428571 0 0 51.428571 0 2969 Tm 33.775 0 Td 74.537037 Tz (2 ) Tj 51.428571 0 0 51.428571 0 2916.873351 Tm 26.036111 0 Td 57.037037 Tz (FIGS. ) Tj 2.022222 0 Td 66.111111 Tz (2A-2C ) Tj 2.255556 0 Td 49.691358 Tz (are ) Tj 1.147222 0 Td 85.339506 Tz (TEM ) Tj 1.808333 0 Td 56.712963 Tz (images ) Tj 2.333333 0 Td 61.574074 Tz (show ) Tj 1.769444 0 Td 58.796296 Tz (polymer ) Tj 2.761111 0 Td 62.5 Tz (nanocap ) Tj 51.428571 0 0 51.428571 0 2874.458693 Tm 25.316667 0 Td 47.314815 Tz (Sules ) Tj 1.672222 0 Td 50.87963 Tz (containing ) Tj 3.286111 0 Td 53.148148 Tz (metal ) Tj 1.827778 0 Td 47.916667 Tz (nanoparticles. ) Tj 4.297222 0 Td 54.282407 Tz (FIG. ) Tj 1.536111 0 Td 74.537037 Tz (2D ) Tj 1.127778 0 Td 58.981481 Tz (shows ) Tj 1.983333 0 Td 57.037037 Tz (X-ray ) Tj 51.428571 0 0 51.428571 0 2830.578313 Tm 25.297222 0 Td 45.664983 Tz (diffraction ) Tj 3.266667 0 Td 47.800926 Tz (patterns ) Tj 2.547222 0 Td 55.092593 Tz (of ) Tj 0.836111 0 Td 53.20216 Tz (nanocapsules ) Tj 4.044444 0 Td 51.851852 Tz (containing ) Tj 3.305556 0 Td 44.830247 Tz (silver ) Tj 1.847222 0 Td 67.24537 Tz (nano ) Tj 51.428571 0 0 51.428571 0 2788.707281 Tm 25.297222 0 Td 45.37037 Tz (particles ) Tj 2.663889 0 Td 46.018519 Tz (\(top\) ) Tj 1.575 0 Td 58.333333 Tz (and ) Tj 1.225 0 Td 55.092593 Tz (blank ) Tj 1.827778 0 Td 53.742284 Tz (nanocapsules ) Tj 4.063889 0 Td 49.691358 Tz (\(bottom\). ) Tj 51.428571 0 0 51.428571 0 2746.179874 Tm 26.036111 0 Td 60.925926 Tz (FIG.3 ) Tj 2.022222 0 Td 59.62963 Tz (shows ) Tj 1.983333 0 Td 84.259259 Tz (UV ) Tj 1.166667 0 Td 60.493827 Tz (and ) Tj 1.225 0 Td 58.333333 Tz (plasmon ) Tj 2.663889 0 Td 53.652263 Tz (resonance ) Tj 3.013889 0 Td 48.611111 Tz (analysis ) Tj 2.508333 0 Td 58.333333 Tz (of ) Tj 0.777778 0 Td 56.712963 Tz (lipo ) Tj 51.428571 0 0 51.428571 0 2706.080148 Tm 25.316667 0 Td 59.62963 Tz (Somes ) Tj 1.963889 0 Td 51.203704 Tz (containing ) Tj 3.169444 0 Td 81.828704 Tz (AgNO ) Tj 2.586111 0 Td 54.012346 Tz (\(A\) ) Tj 1.147222 0 Td 85.87963 Tz (UV ) Tj 1.225 0 Td 48.611111 Tz (spectra ) Tj 2.197222 0 Td 56.712963 Tz (of ) Tj 0.758333 0 Td 54.372428 Tz (liposomes ) Tj 3.111111 0 Td 71.296296 Tz (con ) Tj 52.857143 0 0 52.857143 0 2663.358282 Tm 24.594595 0 Td 47.297297 Tz (taining ) Tj 2.1 0 Td 70 Tz (AgNO, ) Tj 2.345946 0 Td 44.144144 Tz (in ) Tj 0.7 0 Td 47.297297 Tz (the ) Tj 1.002703 0 Td 54.954955 Tz (aqueous ) Tj 2.459459 0 Td 52.027027 Tz (core ) Tj 1.4 0 Td 56.756757 Tz (and ) Tj 1.191892 0 Td 81.981982 Tz (DMPA ) Tj 2.137838 0 Td 44.144144 Tz (in ) Tj 0.681081 0 Td 48.348348 Tz (the ) Tj 1.021622 0 Td 47.747748 Tz (bilayer ) Tj 51.428571 0 0 51.428571 0 2621.291667 Tm 25.297222 0 Td 44.722222 Tz (after ) Tj 1.536111 0 Td 51.851852 Tz (varying ) Tj 2.352778 0 Td 54.6875 Tz (exposure ) Tj 2.819444 0 Td 45.37037 Tz (to ) Tj 0.719444 0 Td 89.12037 Tz (UV ) Tj 1.244444 0 Td 44.722222 Tz (light ) Tj 1.536111 0 Td 42.12963 Tz (\(0, ) Tj 0.952778 0 Td 43.75 Tz (2, ) Tj 0.738889 0 Td 42.12963 Tz (5, ) Tj 0.7 0 Td 45.37037 Tz (8, ) Tj 0.777778 0 Td 47.530864 Tz (12, ) Tj 1.108333 0 Td 46.450617 Tz (16, ) Tj 0.991667 0 Td 60.493827 Tz (and ) Tj 1.263889 0 Td 59.953704 Tz (20 ) Tj 51.428571 0 0 51.428571 0 2577.179678 Tm 25.297222 0 Td 50.05144 Tz (minutes\). ) Tj 2.936111 0 Td 57.253086 Tz (150 ) Tj 1.205556 0 Td 59.953704 Tz (ml ) Tj 0.855556 0 Td 48.206019 Tz (aliquots ) Tj 2.488889 0 Td 58.333333 Tz (were ) Tj 1.555556 0 Td 47.685185 Tz (diluted ) Tj 2.138889 0 Td 45.37037 Tz (in ) Tj 0.719444 0 Td 55.092593 Tz (2 ) Tj 0.505556 0 Td 61.574074 Tz (ml ) Tj 0.894444 0 Td 55.092593 Tz (of ) Tj 0.738889 0 Td 56.30787 Tz (methanol ) Tj 2.858333 0 Td 45.37037 Tz (to ) Tj 51.428571 0 0 51.428571 0 2540.997433 Tm 25.297222 0 Td 51.041667 Tz (lyZe ) Tj 1.613889 0 Td 54.012346 Tz (liposomes ) Tj 3.286111 0 Td 59.41358 Tz (and ) Tj 1.477778 0 Td 56.712963 Tz (minimize ) Tj 3.111111 0 Td 44.074074 Tz (light ) Tj 1.672222 0 Td 45.37037 Tz (scattering. ) Tj 3.402778 0 Td 53.652263 Tz (Gradually ) Tj 51.428571 0 0 51.428571 0 2497.278607 Tm 25.297222 0 Td 51.851852 Tz (decreasing ) Tj 3.305556 0 Td 55.092593 Tz (absorbance ) Tj 3.5 0 Td 46.990741 Tz (at ) Tj 0.777778 0 Td 58.333333 Tz (253 ) Tj 1.322222 0 Td 74.537037 Tz (nm ) Tj 1.166667 0 Td 52.73569 Tz (corresponds ) Tj 3.713889 0 Td 45.37037 Tz (to ) Tj 0.777778 0 Td 50.771605 Tz (the ) Tj 1.127778 0 Td 58.981481 Tz (disap ) Tj 51.428571 0 0 51.428571 0 2453.299145 Tm 25.297222 0 Td 53.877315 Tz (pearance ) Tj 2.761111 0 Td 58.333333 Tz (of ) Tj 0.797222 0 Td 73.240741 Tz (DMPA; ) Tj 2.391667 0 Td 51.131687 Tz (increased ) Tj 2.916667 0 Td 54.768519 Tz (absorbance ) Tj 3.441667 0 Td 45.37037 Tz (at ) Tj 0.719444 0 Td 59.41358 Tz (405 ) Tj 1.283333 0 Td 72.916667 Tz (nm ) Tj 1.088889 0 Td 38.888889 Tz (is ) Tj 0.641667 0 Td 59.953704 Tz (from ) Tj 51.428571 0 0 51.428571 0 2414.731288 Tm 25.316667 0 Td 49.537037 Tz (Surface ) Tj 2.294444 0 Td 58.796296 Tz (plasmon ) Tj 2.761111 0 Td 53.652263 Tz (resonance ) Tj 3.15 0 Td 45.37037 Tz (in ) Tj 0.836111 0 Td 47.685185 Tz (nanoparticles. ) Tj 4.277778 0 Td 52.932099 Tz (\(B\) ) Tj 1.244444 0 Td 60.358796 Tz (Liposome ) Tj 51.428571 0 0 51.428571 0 2372.207921 Tm 25.277778 0 Td 54.282407 Tz (with ) Tj 1.497222 0 Td 58.333333 Tz (a ) Tj 0.583333 0 Td 44.830247 Tz (silver ) Tj 1.827778 0 Td 49.691358 Tz (nanoparticle ) Tj 3.772222 0 Td 56.712963 Tz (produced ) Tj 2.916667 0 Td 46.018519 Tz (after ) Tj 1.555556 0 Td 61.574074 Tz (20 ) Tj 0.972222 0 Td 53.703704 Tz (minutes ) Tj 2.488889 0 Td 58.333333 Tz (of ) Tj 0.816667 0 Td 89.12037 Tz (UV ) Tj 51.428571 0 0 51.428571 0 2330.825666 Tm 25.297222 0 Td 54.282407 Tz (exposure ) Tj 2.780556 0 Td 46.990741 Tz (in ) Tj 0.758333 0 Td 49.691358 Tz (the ) Tj 1.030556 0 Td 53.472222 Tz (presence ) Tj 2.741667 0 Td 56.712963 Tz (of ) Tj 0.797222 0 Td 72.592593 Tz (DMPA. ) Tj 2.391667 0 Td 52.932099 Tz (\(C\) ) Tj 1.147222 0 Td 50.231481 Tz (Increase ) Tj 2.547222 0 Td 58.333333 Tz (of ) Tj 0.777778 0 Td 59.722222 Tz (plasmon ) Tj 51.428571 0 0 51.428571 0 2286.70892 Tm 25.297222 0 Td 54.372428 Tz (resonance ) Tj 3.072222 0 Td 41.203704 Tz (\(filled ) Tj 1.866667 0 Td 42.939815 Tz (circles, ) Tj 2.236111 0 Td 49.151235 Tz (righty-axis\) ) Tj 3.655556 0 Td 59.41358 Tz (and ) Tj 1.225 0 Td 51.851852 Tz (decrease ) Tj 2.605556 0 Td 58.333333 Tz (of ) Tj 0.777778 0 Td 85.069444 Tz (DMPA ) Tj 51.428571 0 0 51.428571 0 2245.966265 Tm 25.316667 0 Td 56.17284 Tz (\(empty ) Tj 2.216667 0 Td 42.939815 Tz (circles, ) Tj 2.236111 0 Td 40.509259 Tz (left ) Tj 1.127778 0 Td 46.296296 Tz (y-axis, ) Tj 2.138889 0 Td 50.356125 Tz (concentration ) Tj 4.122222 0 Td 45.37037 Tz (in ) Tj 0.719444 0 Td 47.685185 Tz (diluted ) Tj 2.216667 0 Td 55.497685 Tz (methanol ) Tj 51.428571 0 0 51.428571 0 2204.179177 Tm 25.316667 0 Td 47.638889 Tz (solutions\) ) Tj 2.994444 0 Td 55.092593 Tz (over ) Tj 1.477778 0 Td 47.962963 Tz (time. ) Tj 1.633333 0 Td 56.17284 Tz (\(D\) ) Tj 1.166667 0 Td 85.87963 Tz (UV ) Tj 1.225 0 Td 48.148148 Tz (spectra ) Tj 2.216667 0 Td 58.333333 Tz (of ) Tj 0.777778 0 Td 56.018519 Tz (aqueous ) Tj 2.547222 0 Td 48.611111 Tz (solutions ) Tj 2.8 0 Td 58.333333 Tz (of ) Tj 51.428571 0 0 51.428571 0 2165.057143 Tm 25.297222 0 Td 59.027778 Tz (monomer-loaded ) Tj 5.191667 0 Td 54.372428 Tz (liposomes ) Tj 3.15 0 Td 51.527778 Tz (containing ) Tj 3.286111 0 Td 75.185185 Tz (AgNO3 ) Tj 2.527778 0 Td 58.333333 Tz (and ) Tj 1.283333 0 Td 85.069444 Tz (DMPA ) Tj 51.428571 0 0 51.428571 0 2120.402597 Tm 25.277778 0 Td 52.391975 Tz (before ) Tj 2.158333 0 Td 47.530864 Tz (\(1\) ) Tj 1.088889 0 Td 60.493827 Tz (and ) Tj 1.322222 0 Td 46.666667 Tz (after ) Tj 1.652778 0 Td 45.37037 Tz (\(2\) ) Tj 1.108333 0 Td 54.6875 Tz (exposure ) Tj 2.877778 0 Td 46.990741 Tz (to ) Tj 0.855556 0 Td 85.87963 Tz (UV ) Tj 1.341667 0 Td 44.020062 Tz (irradiation. ) Tj 3.5 0 Td 42.669753 Tz (Inset: ) Tj 51.428571 0 0 51.428571 0 2082.977058 Tm 25.297222 0 Td 48.881173 Tz (freeze-dried ) Tj 4.141667 0 Td 51.851852 Tz (nanocapsules: ) Tj 4.666667 0 Td 61.574074 Tz (empty ) Tj 2.45 0 Td 46.450617 Tz (\(1\) ) Tj 1.458333 0 Td 60.493827 Tz (and ) Tj 1.672222 0 Td 51.203704 Tz (containing ) Tj 51.428571 0 0 51.428571 0 2041.754678 Tm 25.297222 0 Td 53.292181 Tz (entrapped ) Tj 3.052778 0 Td 45.37037 Tz (silver ) Tj 1.808333 0 Td 49.358974 Tz (nanoparticles ) Tj 4.044444 0 Td 41.319444 Tz (\(2\). ) Tj 38.571429 0 0 38.571429 0 1965 Tm 35.181481 0 Td 97.762346 Tz (DETAILED ) Tj 4.977778 0 Td 94.276094 Tz (DESCRIPTION ) Tj 6.533333 0 Td 99.382716 Tz (OF ) Tj 1.4 0 Td 106.584362 Tz (THE ) Tj 2.177778 0 Td 98.902606 Tz (INVENTION ) Tj 51.428571 0 0 51.428571 0 1876.260417 Tm 26.016667 0 Td 66.435185 Tz (As ) Tj 1.011111 0 Td 55.092593 Tz (used ) Tj 1.477778 0 Td 47.685185 Tz (herein, ) Tj 2.216667 0 Td 49.691358 Tz (the ) Tj 1.069444 0 Td 54.282407 Tz (term ) Tj 1.516667 0 Td 50.231481 Tz ("nanoparticle' ) Tj 4.452778 0 Td 44.830247 Tz (refers ) Tj 1.808333 0 Td 45.37037 Tz (to ) Tj 0.738889 0 Td 51.851852 Tz (a ) Tj 0.525 0 Td 64.166667 Tz (nanos ) Tj 51.428571 0 0 51.428571 0 1835.929471 Tm 25.297222 0 Td 50.231481 Tz (cale ) Tj 1.438889 0 Td 47.800926 Tz (metallic ) Tj 2.547222 0 Td 43.569959 Tz (particle. ) Tj 2.625 0 Td 51.353276 Tz (Nanoparticles ) Tj 4.277778 0 Td 54.012346 Tz (can ) Tj 1.225 0 Td 47.530864 Tz (be, ) Tj 1.108333 0 Td 40.833333 Tz (e.g., ) Tj 1.458333 0 Td 55.092593 Tz (about ) Tj 1.886111 0 Td 48.611111 Tz (0.5 ) Tj 51.428571 0 0 51.428571 0 1794.274131 Tm 25.297222 0 Td 74.537037 Tz (nm ) Tj 1.127778 0 Td 48.611111 Tz (to ) Tj 0.777778 0 Td 53.796296 Tz (about ) Tj 1.847222 0 Td 59.953704 Tz (20 ) Tj 0.933333 0 Td 74.537037 Tz (nm ) Tj 1.127778 0 Td 45.37037 Tz (in ) Tj 0.777778 0 Td 42.12963 Tz (size. ) Tj 1.497222 0 Td 51.602564 Tz (Nanoparticles ) Tj 4.258333 0 Td 55.092593 Tz (can ) Tj 1.186111 0 Td 59.953704 Tz (be ) Tj 0.933333 0 Td 58.333333 Tz (of ) Tj 0.836111 0 Td 51.388889 Tz (varying ) Tj 51.428571 0 0 51.428571 0 1755.044776 Tm 25.316667 0 Td 50 Tz (shapes, ) Tj 2.275 0 Td 55.092593 Tz (such ) Tj 1.516667 0 Td 50.231481 Tz (as ) Tj 0.797222 0 Td 48.251029 Tz (spherical ) Tj 2.819444 0 Td 51.851852 Tz (or ) Tj 0.797222 0 Td 48.021886 Tz (spheroidal. ) Tj 51.428571 0 0 51.428571 0 1710.248705 Tm 26.016667 0 Td 66.435185 Tz (As ) Tj 1.011111 0 Td 55.092593 Tz (used ) Tj 1.477778 0 Td 47.222222 Tz (herein, ) Tj 2.197222 0 Td 49.691358 Tz (the ) Tj 1.069444 0 Td 54.282407 Tz (term ) Tj 1.477778 0 Td 54.095442 Tz (nanocapsule ) Tj 4.452778 0 Td 45.37037 Tz (refers ) Tj 1.827778 0 Td 45.37037 Tz (to ) Tj 0.738889 0 Td 51.851852 Tz (a ) Tj 0.486111 0 Td 55.632716 Tz (hollow ) Tj 51.428571 0 0 51.428571 0 1668.421053 Tm 25.297222 0 Td 54.372428 Tz (polymeric ) Tj 3.091667 0 Td 45.37037 Tz (shell ) Tj 1.516667 0 Td 53.472222 Tz (or ) Tj 0.719444 0 Td 51.851852 Tz (enclosure ) Tj 2.955556 0 Td 55.092593 Tz (having ) Tj 2.1 0 Td 56.712963 Tz (an ) Tj 0.816667 0 Td 51.851852 Tz (outer ) Tj 1.672222 0 Td 45.37037 Tz (shell ) Tj 1.497222 0 Td 51.851852 Tz (wall ) Tj 1.4 0 Td 56.388889 Tz (defin ) Tj 52.857143 0 0 52.857143 0 1626.985419 Tm 24.613514 0 Td 50.45045 Tz (ing ) Tj 1.021622 0 Td 56.756757 Tz (an ) Tj 0.851351 0 Td 43.75 Tz (interior ) Tj 2.213514 0 Td 47.822823 Tz (space. ) Tj 1.891892 0 Td 54.391892 Tz (Nanocapsules ) Tj 4.086486 0 Td 52.552553 Tz (can ) Tj 1.116216 0 Td 46.246246 Tz (be, ) Tj 0.964865 0 Td 40.36036 Tz (e.g., ) Tj 1.343243 0 Td 53.603604 Tz (about ) Tj 1.740541 0 Td 61.486486 Tz (40 ) Tj 0.87027 0 Td 75.675676 Tz (nm ) Tj 51.428571 0 0 51.428571 0 1585.150311 Tm 25.277778 0 Td 46.990741 Tz (to ) Tj 0.738889 0 Td 55.092593 Tz (about ) Tj 1.827778 0 Td 61.574074 Tz (50 ) Tj 0.933333 0 Td 54.62963 Tz (microns ) Tj 2.488889 0 Td 45.37037 Tz (in ) Tj 0.738889 0 Td 43.425926 Tz (size. ) Tj 1.516667 0 Td 55.632716 Tz (Nanocapsules ) Tj 4.219444 0 Td 54.012346 Tz (can ) Tj 1.147222 0 Td 59.953704 Tz (be ) Tj 0.894444 0 Td 58.333333 Tz (of ) Tj 0.816667 0 Td 51.388889 Tz (varying ) Tj 51.428571 0 0 51.428571 0 1546.044776 Tm 25.316667 0 Td 50 Tz (shapes, ) Tj 2.275 0 Td 55.092593 Tz (such ) Tj 1.516667 0 Td 50.231481 Tz (as ) Tj 0.797222 0 Td 48.251029 Tz (spherical ) Tj 2.819444 0 Td 51.851852 Tz (or ) Tj 0.797222 0 Td 48.021886 Tz (spheroidal. ) Tj 51.428571 0 0 51.428571 0 1503.255754 Tm 26.036111 0 Td 48.611111 Tz (In ) Tj 0.797222 0 Td 57.253086 Tz (one ) Tj 1.186111 0 Td 48.148148 Tz (aspect, ) Tj 2.177778 0 Td 51.851852 Tz (the ) Tj 1.108333 0 Td 49.691358 Tz (invention ) Tj 2.877778 0 Td 51.851852 Tz (provides ) Tj 2.683333 0 Td 55.092593 Tz (a ) Tj 0.544444 0 Td 51.851852 Tz (metal ) Tj 1.788889 0 Td 49.691358 Tz (nanoparticle ) Tj 51.428571 0 0 51.428571 0 1463.421437 Tm 25.297222 0 Td 53.292181 Tz (entrapped ) Tj 3.052778 0 Td 51.851852 Tz (or ) Tj 0.777778 0 Td 52.121914 Tz (encapsulated ) Tj 3.927778 0 Td 46.990741 Tz (in ) Tj 0.738889 0 Td 55.092593 Tz (a ) Tj 0.505556 0 Td 58.333333 Tz (polymer ) Tj 2.644444 0 Td 51.851852 Tz (nanocapsule. ) Tj 3.947222 0 Td 45.37037 Tz (In ) Tj 0.777778 0 Td 60.493827 Tz (cer ) Tj 51.428571 0 0 51.428571 0 1416.783191 Tm 25.277778 0 Td 45.37037 Tz (tain ) Tj 1.263889 0 Td 56.983025 Tz (embodiments, ) Tj 4.297222 0 Td 49.691358 Tz (the ) Tj 1.108333 0 Td 52.5 Tz (metal ) Tj 1.788889 0 Td 49.421296 Tz (nanoparticle ) Tj 3.752778 0 Td 37.268519 Tz (is ) Tj 0.622222 0 Td 58.333333 Tz (a ) Tj 0.544444 0 Td 52.5 Tz (metal ) Tj 1.769444 0 Td 49.421296 Tz (selected ) Tj 51.428571 0 0 51.428571 0 1379.148987 Tm 25.297222 0 Td 58.333333 Tz (from ) Tj 1.555556 0 Td 50.771605 Tz (the ) Tj 1.030556 0 Td 57.037037 Tz (group ) Tj 1.905556 0 Td 48.935185 Tz (consisting ) Tj 3.072222 0 Td 56.712963 Tz (of ) Tj 0.758333 0 Td 41.666667 Tz (silver, ) Tj 1.905556 0 Td 51.131687 Tz (platinum, ) Tj 2.936111 0 Td 51.527778 Tz (palladium, ) Tj 3.247222 0 Td 59.41358 Tz (and ) Tj 51.428571 0 0 51.428571 0 1334.448399 Tm 25.297222 0 Td 47.962963 Tz (gold. ) Tj 1.633333 0 Td 45.37037 Tz (In ) Tj 0.680556 0 Td 47.685185 Tz (certain ) Tj 2.080556 0 Td 57.253086 Tz (embodiments, ) Tj 4.238889 0 Td 50.771605 Tz (the ) Tj 1.05 0 Td 52.5 Tz (metal ) Tj 1.730556 0 Td 49.691358 Tz (nanoparticle ) Tj 3.694444 0 Td 40.509259 Tz (is ) Tj 0.602778 0 Td 41.203704 Tz (silver. ) Tj 51.428571 0 0 51.428571 0 1294.371274 Tm 25.316667 0 Td 46.990741 Tz (In ) Tj 1.05 0 Td 46.296296 Tz (certain ) Tj 2.391667 0 Td 56.712963 Tz (embodiments, ) Tj 4.530556 0 Td 49.691358 Tz (the ) Tj 1.322222 0 Td 58.796296 Tz (polymer ) Tj 2.897222 0 Td 54.208754 Tz (nanocapsule ) Tj 4.005556 0 Td 40.509259 Tz (is ) Tj 0.933333 0 Td 55.092593 Tz (a ) Tj 51.428571 0 0 51.428571 0 1254.340369 Tm 25.297222 0 Td 58.333333 Tz (copolymer ) Tj 3.519444 0 Td 59.953704 Tz (of ) Tj 0.991667 0 Td 51.851852 Tz (a ) Tj 0.758333 0 Td 50.462963 Tz (styrene ) Tj 2.508333 0 Td 52.662037 Tz (with ) Tj 1.691667 0 Td 50.771605 Tz (divinylbenzene. ) Tj 5.016667 0 Td 48.611111 Tz (In ) Tj 0.972222 0 Td 48.148148 Tz (certain ) Tj 51.428571 0 0 51.428571 0 1212.676617 Tm 25.297222 0 Td 56.983025 Tz (embodiments, ) Tj 4.355556 0 Td 50.771605 Tz (the ) Tj 1.186111 0 Td 58.333333 Tz (polymer ) Tj 2.722222 0 Td 54.208754 Tz (nanocapsule ) Tj 3.869444 0 Td 37.268519 Tz (is ) Tj 0.719444 0 Td 58.333333 Tz (a ) Tj 0.641667 0 Td 57.613169 Tz (copolymer ) Tj 3.383333 0 Td 56.712963 Tz (of ) Tj 51.428571 0 0 51.428571 0 1170.794045 Tm 25.277778 0 Td 47.276688 Tz (tert-butylstyrene ) Tj 5.172222 0 Td 53.472222 Tz (with ) Tj 1.652778 0 Td 50.771605 Tz (divinylbenzene. ) Tj 4.977778 0 Td 46.990741 Tz (In ) Tj 0.913889 0 Td 47.222222 Tz (certain ) Tj 2.313889 0 Td 68.055556 Tz (embodi ) Tj 51.428571 0 0 51.428571 0 1126.630273 Tm 25.297222 0 Td 52.932099 Tz (ments, ) Tj 2.061111 0 Td 50.771605 Tz (the ) Tj 1.108333 0 Td 53.914141 Tz (nanocapsule ) Tj 3.713889 0 Td 54.012346 Tz (has ) Tj 1.127778 0 Td 58.333333 Tz (a ) Tj 0.505556 0 Td 46.990741 Tz (size ) Tj 1.302778 0 Td 43.75 Tz (in ) Tj 0.719444 0 Td 49.691358 Tz (the ) Tj 1.069444 0 Td 53.148148 Tz (range ) Tj 1.75 0 Td 58.333333 Tz (of ) Tj 0.758333 0 Td 57.79321 Tz (40-120 ) Tj 2.275 0 Td 58.333333 Tz (nm. ) Tj 51.428571 0 0 51.428571 0 1084.812808 Tm 25.316667 0 Td 46.990741 Tz (In ) Tj 0.797222 0 Td 46.759259 Tz (certain ) Tj 2.138889 0 Td 56.712963 Tz (embodiments, ) Tj 4.258333 0 Td 50.771605 Tz (the ) Tj 1.108333 0 Td 53.148148 Tz (metal ) Tj 1.808333 0 Td 49.691358 Tz (nanoparticle ) Tj 3.733333 0 Td 55.092593 Tz (has ) Tj 1.166667 0 Td 51.851852 Tz (a ) Tj 0.525 0 Td 46.180556 Tz (size ) Tj 1.322222 0 Td 56.712963 Tz (of ) Tj 51.428571 0 0 51.428571 0 1043.559598 Tm 25.297222 0 Td 54.444444 Tz (about ) Tj 1.886111 0 Td 53.472222 Tz (1-10 ) Tj 1.516667 0 Td 59.41358 Tz (nm, ) Tj 1.283333 0 Td 62.384259 Tz (more ) Tj 1.691667 0 Td 49.583333 Tz (preferably ) Tj 3.188889 0 Td 54.444444 Tz (about ) Tj 1.847222 0 Td 51.851852 Tz (5-6 ) Tj 1.166667 0 Td 60.493827 Tz (nm, ) Tj 1.322222 0 Td 58.333333 Tz (most ) Tj 1.575 0 Td 55.092593 Tz (prefer ) Tj 51.428571 0 0 51.428571 0 1002.018397 Tm 25.297222 0 Td 51.851852 Tz (ably ) Tj 1.555556 0 Td 55.092593 Tz (about ) Tj 1.983333 0 Td 48.611111 Tz (5.5 ) Tj 1.244444 0 Td 58.333333 Tz (nm. ) Tj 1.438889 0 Td 45.37037 Tz (In ) Tj 0.855556 0 Td 47.222222 Tz (certain ) Tj 2.333333 0 Td 56.712963 Tz (embodiments, ) Tj 4.433333 0 Td 48.611111 Tz (the ) Tj 1.166667 0 Td 59.259259 Tz (polymer ) Tj 51.428571 0 0 51.428571 0 963.064748 Tm 25.297222 0 Td 54.503367 Tz (nanocapsule ) Tj 3.772222 0 Td 47.222222 Tz (further ) Tj 2.119444 0 Td 50.231481 Tz (includes ) Tj 2.605556 0 Td 50.231481 Tz (or ) Tj 0.738889 0 Td 50 Tz (entraps ) Tj 2.236111 0 Td 58.333333 Tz (a ) Tj 0.505556 0 Td 55.902778 Tz (drug ) Tj 1.516667 0 Td 50.231481 Tz (or ) Tj 0.738889 0 Td 48.905724 Tz (therapeutic ) Tj 51.428571 0 0 51.428571 0 924.776119 Tm 25.297222 0 Td 53.148148 Tz (agent ) Tj 1.788889 0 Td 39.429012 Tz (\(e.g., ) Tj 1.633333 0 Td 48.611111 Tz (a ) Tj 0.505556 0 Td 53.674769 Tz (chemotherapeutic ) Tj 5.347222 0 Td 46.759259 Tz (agent\). ) Tj 51.428571 0 0 51.428571 0 877.967908 Tm 26.036111 0 Td 48.611111 Tz (In ) Tj 0.758333 0 Td 52.777778 Tz (another ) Tj 2.352778 0 Td 47.222222 Tz (aspect, ) Tj 2.197222 0 Td 49.691358 Tz (the ) Tj 1.069444 0 Td 49.691358 Tz (invention ) Tj 2.877778 0 Td 51.446759 Tz (provides ) Tj 2.663889 0 Td 55.092593 Tz (a ) Tj 0.525 0 Td 59.953704 Tz (method ) Tj 2.352778 0 Td 55.092593 Tz (of ) Tj 0.758333 0 Td 64.814815 Tz (pre ) Tj 51.428571 0 0 51.428571 0 839.245614 Tm 25.297222 0 Td 51.851852 Tz (paring ) Tj 2.1 0 Td 55.092593 Tz (a ) Tj 0.602778 0 Td 52.5 Tz (metal ) Tj 1.866667 0 Td 49.421296 Tz (nanoparticle ) Tj 3.772222 0 Td 53.652263 Tz (entrapped ) Tj 3.130556 0 Td 53.472222 Tz (or ) Tj 0.836111 0 Td 52.662037 Tz (encapsulated ) Tj 4.044444 0 Td 43.75 Tz (in ) Tj 0.797222 0 Td 55.092593 Tz (a ) Tj 51.428571 0 0 51.428571 0 798.510083 Tm 25.297222 0 Td 58.333333 Tz (polymer ) Tj 2.663889 0 Td 51.851852 Tz (nanocapsule, ) Tj 3.947222 0 Td 49.691358 Tz (the ) Tj 1.127778 0 Td 59.953704 Tz (method ) Tj 2.372222 0 Td 54.444444 Tz (comprising ) Tj 3.461111 0 Td 54.012346 Tz (polymerizing ) Tj 51.428571 0 0 51.428571 0 753.137453 Tm 25.297222 0 Td 63.599537 Tz (monomers ) Tj 3.344444 0 Td 48.611111 Tz (to ) Tj 0.894444 0 Td 57.523148 Tz (form ) Tj 1.672222 0 Td 50.771605 Tz (the ) Tj 1.205556 0 Td 58.796296 Tz (polymer ) Tj 2.741667 0 Td 54.208754 Tz (nanocapsule ) Tj 3.869444 0 Td 59.41358 Tz (and ) Tj 1.361111 0 Td 56.481481 Tz (simulta ) Tj 51.428571 0 0 51.428571 0 713.236453 Tm 25.297222 0 Td 53.703704 Tz (neously ) Tj 2.488889 0 Td 56.481481 Tz (forming ) Tj 2.566667 0 Td 49.691358 Tz (the ) Tj 1.127778 0 Td 53.148148 Tz (metal ) Tj 1.847222 0 Td 47.863248 Tz (nanoparticle. ) Tj 4.005556 0 Td 46.990741 Tz (In ) Tj 0.797222 0 Td 46.759259 Tz (certain ) Tj 2.216667 0 Td 66.975309 Tz (embodi ) Tj 51.428571 0 0 51.428571 0 669.679901 Tm 25.297222 0 Td 52.932099 Tz (ments, ) Tj 2.177778 0 Td 49.691358 Tz (the ) Tj 1.166667 0 Td 63.194444 Tz (monomers ) Tj 3.305556 0 Td 49.691358 Tz (are ) Tj 1.127778 0 Td 55.681818 Tz (polymerized ) Tj 3.927778 0 Td 52.5 Tz (using ) Tj 1.808333 0 Td 58.333333 Tz (a ) Tj 0.602778 0 Td 46.450617 Tz (free-radical ) Tj 51.428571 0 0 51.428571 0 627.278496 Tm 25.297222 0 Td 40.185185 Tz (initiator. ) Tj 2.586111 0 Td 46.990741 Tz (In ) Tj 0.7 0 Td 46.759259 Tz (certain ) Tj 2.1 0 Td 56.983025 Tz (embodiments, ) Tj 4.2 0 Td 50.771605 Tz (the ) Tj 1.05 0 Td 63.194444 Tz (monomers ) Tj 3.15 0 Td 50.771605 Tz (are ) Tj 1.030556 0 Td 62.962963 Tz (polymer ) Tj 51.428571 0 0 51.428571 0 586.677419 Tm 25.297222 0 Td 51.041667 Tz (ized ) Tj 1.536111 0 Td 46.990741 Tz (in ) Tj 0.894444 0 Td 51.851852 Tz (a ) Tj 0.661111 0 Td 44.722222 Tz (lipid ) Tj 1.633333 0 Td 44.965278 Tz (bilayer. ) Tj 2.527778 0 Td 48.611111 Tz (In ) Tj 0.913889 0 Td 46.759259 Tz (certain ) Tj 2.313889 0 Td 56.983025 Tz (embodiments, ) Tj 4.452778 0 Td 48.611111 Tz (the ) Tj 1.205556 0 Td 44.722222 Tz (lipid ) Tj 51.428571 0 0 51.428571 0 546.3861 Tm 25.277778 0 Td 49.074074 Tz (bilayer ) Tj 2.294444 0 Td 38.888889 Tz (is ) Tj 0.7 0 Td 55.092593 Tz (a ) Tj 0.602778 0 Td 44.722222 Tz (lipid ) Tj 1.575 0 Td 49.074074 Tz (bilayer ) Tj 2.255556 0 Td 59.953704 Tz (of ) Tj 0.875 0 Td 51.851852 Tz (a ) Tj 0.583333 0 Td 52.211934 Tz (liposome. ) Tj 3.111111 0 Td 46.990741 Tz (In ) Tj 0.816667 0 Td 47.222222 Tz (certain ) Tj 2.216667 0 Td 68.055556 Tz (embodi ) Tj 51.428571 0 0 51.428571 0 503.089835 Tm 25.297222 0 Td 52.932099 Tz (ments, ) Tj 2.022222 0 Td 50.771605 Tz (the ) Tj 1.030556 0 Td 53.148148 Tz (metal ) Tj 1.75 0 Td 49.691358 Tz (nanoparticle ) Tj 3.694444 0 Td 38.888889 Tz (is ) Tj 0.583333 0 Td 58.333333 Tz (formed ) Tj 2.216667 0 Td 59.953704 Tz (by ) Tj 0.855556 0 Td 46.180556 Tz (free-radical ) Tj 3.461111 0 Td 61.574074 Tz (reduc ) Tj 51.428571 0 0 51.428571 0 461.143921 Tm 25.277778 0 Td 46.990741 Tz (tion ) Tj 1.341667 0 Td 56.712963 Tz (of ) Tj 0.777778 0 Td 55.092593 Tz (a ) Tj 0.525 0 Td 55.902778 Tz (metalion ) Tj 2.858333 0 Td 50.771605 Tz (dissolved ) Tj 2.936111 0 Td 45.37037 Tz (in ) Tj 0.7 0 Td 58.333333 Tz (an ) Tj 0.894444 0 Td 56.481481 Tz (aqueous ) Tj 2.586111 0 Td 49.537037 Tz (solvent ) Tj 2.216667 0 Td 50.771605 Tz (phase. ) Tj 2.080556 0 Td 48.611111 Tz (In ) Tj 51.428571 0 0 51.428571 0 420.041112 Tm 25.297222 0 Td 46.759259 Tz (certain ) Tj 2.158333 0 Td 56.712963 Tz (embodiments, ) Tj 4.297222 0 Td 49.691358 Tz (the ) Tj 1.108333 0 Td 59.953704 Tz (method ) Tj 2.352778 0 Td 47.685185 Tz (further ) Tj 2.158333 0 Td 54.372428 Tz (comprises ) Tj 3.169444 0 Td 48.611111 Tz (the ) Tj 1.05 0 Td 48.611111 Tz (step ) Tj 51.428571 0 0 51.428571 0 380.702211 Tm 25.297222 0 Td 58.333333 Tz (of ) Tj 0.933333 0 Td 57.523148 Tz (removing ) Tj 3.072222 0 Td 48.611111 Tz (the ) Tj 1.166667 0 Td 44.722222 Tz (lipid ) Tj 1.652778 0 Td 48.611111 Tz (bilayer ) Tj 2.294444 0 Td 46.018519 Tz (after ) Tj 1.672222 0 Td 48.971193 Tz (synthesis ) Tj 2.936111 0 Td 61.574074 Tz (of ) Tj 0.933333 0 Td 49.691358 Tz (the ) Tj 1.225 0 Td 52.5 Tz (metal ) Tj 51.428571 0 0 51.428571 0 342.472779 Tm 25.297222 0 Td 49.96142 Tz (nanoparticle ) Tj 3.772222 0 Td 53.292181 Tz (entrapped ) Tj 3.072222 0 Td 45.37037 Tz (in ) Tj 0.719444 0 Td 58.333333 Tz (a ) Tj 0.505556 0 Td 58.796296 Tz (polymer ) Tj 2.644444 0 Td 51.851852 Tz (nanocapsule. ) Tj 51.428571 0 0 51.428571 0 295.967908 Tm 26.036111 0 Td 48.611111 Tz (In ) Tj 0.758333 0 Td 52.777778 Tz (another ) Tj 2.352778 0 Td 47.222222 Tz (aspect, ) Tj 2.197222 0 Td 49.691358 Tz (the ) Tj 1.069444 0 Td 49.691358 Tz (invention ) Tj 2.877778 0 Td 51.446759 Tz (provides ) Tj 2.663889 0 Td 55.092593 Tz (a ) Tj 0.525 0 Td 59.953704 Tz (method ) Tj 2.352778 0 Td 55.092593 Tz (of ) Tj 0.758333 0 Td 64.814815 Tz (pre ) Tj 51.428571 0 0 51.428571 0 257.610778 Tm 25.297222 0 Td 51.851852 Tz (paring ) Tj 1.983333 0 Td 58.333333 Tz (a ) Tj 0.525 0 Td 53.148148 Tz (metal ) Tj 1.788889 0 Td 49.421296 Tz (nanoparticle ) Tj 3.713889 0 Td 52.932099 Tz (entrapped ) Tj 3.033333 0 Td 43.75 Tz (in ) Tj 0.680556 0 Td 58.333333 Tz (a ) Tj 0.466667 0 Td 59.259259 Tz (polymer ) Tj 2.625 0 Td 62.962963 Tz (nanocap ) Tj 51.428571 0 0 51.428571 0 215.333333 Tm 25.316667 0 Td 44.074074 Tz (Sule, ) Tj 1.652778 0 Td 49.691358 Tz (the ) Tj 1.225 0 Td 59.953704 Tz (method ) Tj 2.488889 0 Td 54.444444 Tz (comprising ) Tj 3.577778 0 Td 52.211934 Tz (providing ) Tj 3.111111 0 Td 58.333333 Tz (an ) Tj 1.011111 0 Td 56.944444 Tz (aqueous ) Tj 2.722222 0 Td 55.740741 Tz (phase ) Tj 51.428571 0 0 51.428571 0 171.679198 Tm 25.297222 0 Td 51.203704 Tz (containing ) Tj 3.363889 0 Td 45.37037 Tz (vesicles, ) Tj 2.741667 0 Td 55.092593 Tz (wherein ) Tj 2.605556 0 Td 49.691358 Tz (the ) Tj 1.127778 0 Td 56.944444 Tz (aqueous ) Tj 2.663889 0 Td 55.740741 Tz (phase ) Tj 1.963889 0 Td 49.826389 Tz (includes ) Tj 2.683333 0 Td 55.092593 Tz (a ) Tj ET Q endstream endobj 154 0 obj << /Length 1 >> stream q endstream endobj 155 0 obj << /Length 50949 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 62.857143 0 0 62.857143 0 3023 Tm 17.325 0 Td 83.522727 Tz (US ) Tj 1.209091 0 Td 57.744108 Tz (9.248,441 ) Tj 3.420455 0 Td 74.242424 Tz (B2 ) Tj 52.857143 0 0 52.857143 0 2968 Tm 14.454054 0 Td 72.522523 Tz (3 ) Tj 51.428571 0 0 51.428571 0 2914.336562 Tm 6.358333 0 Td 55.902778 Tz (metalion ) Tj 2.838889 0 Td 53.472222 Tz (or ) Tj 0.758333 0 Td 42.12963 Tz (salt ) Tj 1.147222 0 Td 58.333333 Tz (and ) Tj 1.166667 0 Td 51.851852 Tz (the ) Tj 1.088889 0 Td 46.990741 Tz (vesicles ) Tj 2.411111 0 Td 55.902778 Tz (comprise ) Tj 2.8 0 Td 45.37037 Tz (at ) Tj 0.7 0 Td 44.074074 Tz (least ) Tj 1.458333 0 Td 59.41358 Tz (one ) Tj 1.225 0 Td 77.777778 Tz (mono ) Tj 51.428571 0 0 51.428571 0 2871.975309 Tm 6.358333 0 Td 54.282407 Tz (mer, ) Tj 1.497222 0 Td 59.41358 Tz (and ) Tj 1.244444 0 Td 54.012346 Tz (polymerizing ) Tj 4.025 0 Td 50.771605 Tz (the ) Tj 1.069444 0 Td 46.990741 Tz (at ) Tj 0.719444 0 Td 44.722222 Tz (least ) Tj 1.516667 0 Td 58.333333 Tz (one ) Tj 1.244444 0 Td 66.203704 Tz (monomer ) Tj 2.936111 0 Td 45.37037 Tz (to ) Tj 0.758333 0 Td 58.333333 Tz (form ) Tj 1.575 0 Td 49.691358 Tz (the ) Tj 51.428571 0 0 51.428571 0 2832.24553 Tm 6.358333 0 Td 58.333333 Tz (polymer ) Tj 2.663889 0 Td 53.914141 Tz (nanocapsule ) Tj 3.733333 0 Td 60.493827 Tz (and ) Tj 1.263889 0 Td 52.083333 Tz (simultaneously ) Tj 4.569444 0 Td 56.018519 Tz (forming ) Tj 2.547222 0 Td 49.691358 Tz (the ) Tj 1.088889 0 Td 53.148148 Tz (metal ) Tj 51.428571 0 0 51.428571 0 2788.431566 Tm 6.358333 0 Td 49.96142 Tz (nanoparticle ) Tj 3.811111 0 Td 53.652263 Tz (entrapped ) Tj 3.130556 0 Td 45.37037 Tz (in ) Tj 0.777778 0 Td 50.771605 Tz (the ) Tj 1.108333 0 Td 58.796296 Tz (polymer ) Tj 2.722222 0 Td 51.58179 Tz (nanocapsule. ) Tj 4.005556 0 Td 45.37037 Tz (In ) Tj 0.816667 0 Td 60.493827 Tz (cer ) Tj 51.428571 0 0 51.428571 0 2740.853659 Tm 6.338889 0 Td 46.180556 Tz (tain ) Tj 1.283333 0 Td 57.253086 Tz (embodiments, ) Tj 4.316667 0 Td 49.691358 Tz (the ) Tj 1.088889 0 Td 43.75 Tz (at ) Tj 0.738889 0 Td 44.074074 Tz (least ) Tj 1.536111 0 Td 57.253086 Tz (one ) Tj 1.244444 0 Td 66.203704 Tz (monomer ) Tj 2.975 0 Td 38.888889 Tz (is ) Tj 0.641667 0 Td 55.976431 Tz (polymerized ) Tj 51.428571 0 0 51.428571 0 2695.806888 Tm 6.338889 0 Td 53.148148 Tz (using ) Tj 1.788889 0 Td 58.333333 Tz (a ) Tj 0.544444 0 Td 46.450617 Tz (free-radical ) Tj 3.577778 0 Td 40.185185 Tz (initiator. ) Tj 2.663889 0 Td 46.990741 Tz (In ) Tj 0.797222 0 Td 46.759259 Tz (certain ) Tj 2.158333 0 Td 57.253086 Tz (embodiments, ) Tj 4.336111 0 Td 49.691358 Tz (the ) Tj 1.069444 0 Td 46.990741 Tz (at ) Tj 51.428571 0 0 51.428571 0 2654.712821 Tm 6.358333 0 Td 44.722222 Tz (least ) Tj 1.555556 0 Td 60.493827 Tz (one ) Tj 1.361111 0 Td 66.203704 Tz (monomer ) Tj 3.013889 0 Td 37.268519 Tz (is ) Tj 0.680556 0 Td 55.387205 Tz (polymerized ) Tj 3.908333 0 Td 45.37037 Tz (in ) Tj 0.797222 0 Td 51.851852 Tz (a ) Tj 0.583333 0 Td 44.722222 Tz (lipid ) Tj 1.575 0 Td 48.611111 Tz (bilayer ) Tj 2.255556 0 Td 59.953704 Tz (of ) Tj 0.855556 0 Td 49.691358 Tz (the ) Tj 51.428571 0 0 51.428571 0 2610.445283 Tm 6.358333 0 Td 45.010288 Tz (vesicles. ) Tj 2.722222 0 Td 46.990741 Tz (In ) Tj 0.777778 0 Td 47.222222 Tz (certain ) Tj 2.197222 0 Td 56.983025 Tz (embodiments, ) Tj 4.336111 0 Td 48.611111 Tz (the ) Tj 1.108333 0 Td 44.074074 Tz (lipid ) Tj 1.516667 0 Td 49.074074 Tz (bilayer ) Tj 2.255556 0 Td 38.888889 Tz (is ) Tj 0.661111 0 Td 51.851852 Tz (a ) Tj 0.583333 0 Td 44.722222 Tz (lipid ) Tj 51.428571 0 0 51.428571 0 2566.614987 Tm 6.338889 0 Td 49.537037 Tz (bilayer ) Tj 2.352778 0 Td 58.333333 Tz (of ) Tj 0.913889 0 Td 55.092593 Tz (a ) Tj 0.622222 0 Td 52.572016 Tz (liposome. ) Tj 3.188889 0 Td 46.990741 Tz (In ) Tj 0.913889 0 Td 46.296296 Tz (certain ) Tj 2.275 0 Td 56.712963 Tz (embodiments, ) Tj 4.394444 0 Td 50.771605 Tz (the ) Tj 1.225 0 Td 53.148148 Tz (metal ) Tj 51.428571 0 0 51.428571 0 2522.232791 Tm 6.358333 0 Td 49.96142 Tz (nanoparticle ) Tj 3.85 0 Td 38.888889 Tz (is ) Tj 0.738889 0 Td 57.79321 Tz (formed ) Tj 2.294444 0 Td 61.574074 Tz (by ) Tj 0.991667 0 Td 46.450617 Tz (free-radical ) Tj 3.597222 0 Td 50.411523 Tz (reduction ) Tj 2.975 0 Td 59.953704 Tz (of ) Tj 0.836111 0 Td 48.611111 Tz (a ) Tj 0.602778 0 Td 52.5 Tz (metal ) Tj 51.428571 0 0 51.428571 0 2479.099154 Tm 6.358333 0 Td 50.771605 Tz (ion ) Tj 1.088889 0 Td 50.771605 Tz (dissolved ) Tj 2.877778 0 Td 43.75 Tz (in ) Tj 0.661111 0 Td 56.712963 Tz (an ) Tj 0.816667 0 Td 56.944444 Tz (aqueous ) Tj 2.566667 0 Td 49.537037 Tz (solvent ) Tj 2.177778 0 Td 50.771605 Tz (phase. ) Tj 2.022222 0 Td 46.990741 Tz (In ) Tj 0.738889 0 Td 46.296296 Tz (certain ) Tj 2.1 0 Td 66.975309 Tz (embodi ) Tj 51.428571 0 0 51.428571 0 2436.354839 Tm 6.358333 0 Td 52.932099 Tz (ments, ) Tj 2.041667 0 Td 50.771605 Tz (the ) Tj 1.05 0 Td 60.493827 Tz (method ) Tj 2.313889 0 Td 47.685185 Tz (further ) Tj 2.1 0 Td 54.372428 Tz (comprises ) Tj 3.091667 0 Td 49.691358 Tz (the ) Tj 1.05 0 Td 46.990741 Tz (step ) Tj 1.302778 0 Td 55.092593 Tz (of ) Tj 0.738889 0 Td 57.523148 Tz (removing ) Tj 2.897222 0 Td 49.691358 Tz (the ) Tj 51.428571 0 0 51.428571 0 2394.435616 Tm 6.358333 0 Td 44.722222 Tz (lipid ) Tj 1.827778 0 Td 48.611111 Tz (bilayer ) Tj 2.508333 0 Td 45.37037 Tz (after ) Tj 1.808333 0 Td 49.331276 Tz (synthesis ) Tj 3.130556 0 Td 61.574074 Tz (of ) Tj 1.127778 0 Td 49.691358 Tz (the ) Tj 1.4 0 Td 51.851852 Tz (metal ) Tj 2.080556 0 Td 49.96142 Tz (nanoparticle ) Tj 51.428571 0 0 51.428571 0 2353.295499 Tm 6.358333 0 Td 53.292181 Tz (entrapped ) Tj 3.052778 0 Td 45.37037 Tz (in ) Tj 0.738889 0 Td 55.092593 Tz (a ) Tj 0.505556 0 Td 58.796296 Tz (polymer ) Tj 2.644444 0 Td 51.58179 Tz (nanocapsule. ) Tj 51.428571 0 0 51.428571 0 2305.128269 Tm 7.116667 0 Td 46.990741 Tz (In ) Tj 0.7 0 Td 53.240741 Tz (another ) Tj 2.333333 0 Td 48.148148 Tz (aspect, ) Tj 2.158333 0 Td 50.771605 Tz (the ) Tj 1.069444 0 Td 49.691358 Tz (invention ) Tj 2.838889 0 Td 51.851852 Tz (provides ) Tj 2.683333 0 Td 57.87037 Tz (methods ) Tj 2.586111 0 Td 56.712963 Tz (of ) Tj 0.758333 0 Td 53.148148 Tz (using ) Tj 51.428571 0 0 51.428571 0 2264.303614 Tm 6.358333 0 Td 55.092593 Tz (a ) Tj 0.544444 0 Td 51.851852 Tz (metal ) Tj 1.769444 0 Td 49.691358 Tz (nanoparticle ) Tj 3.713889 0 Td 53.652263 Tz (entrapped ) Tj 3.072222 0 Td 53.472222 Tz (or ) Tj 0.758333 0 Td 52.662037 Tz (encapsulated ) Tj 3.947222 0 Td 46.990741 Tz (in ) Tj 0.738889 0 Td 55.092593 Tz (a ) Tj 0.505556 0 Td 58.333333 Tz (polymer ) Tj 51.428571 0 0 51.428571 0 2220.536196 Tm 6.358333 0 Td 52.121914 Tz (nanocapsule. ) Tj 4.063889 0 Td 56.388889 Tz (Entrapment ) Tj 3.655556 0 Td 58.333333 Tz (of ) Tj 0.894444 0 Td 53.148148 Tz (metal ) Tj 1.905556 0 Td 49.109687 Tz (nanoparticles ) Tj 4.102778 0 Td 46.990741 Tz (in ) Tj 0.816667 0 Td 56.17284 Tz (hollow ) Tj 51.428571 0 0 51.428571 0 2177.303614 Tm 6.358333 0 Td 52.849003 Tz (nano-capsules ) Tj 4.394444 0 Td 66.975309 Tz (may ) Tj 1.497222 0 Td 46.666667 Tz (offer ) Tj 1.613889 0 Td 48.148148 Tz (several ) Tj 2.275 0 Td 51.262626 Tz (advantages. ) Tj 3.675 0 Td 51.353276 Tz (Nanoparticles ) Tj 51.428571 0 0 51.428571 0 2129.004819 Tm 6.358333 0 Td 69.135802 Tz (may ) Tj 1.419444 0 Td 59.953704 Tz (be ) Tj 0.855556 0 Td 46.666667 Tz (stabilized ) Tj 2.975 0 Td 52.777778 Tz (without ) Tj 2.391667 0 Td 48.611111 Tz (the ) Tj 1.069444 0 Td 55.092593 Tz (need ) Tj 1.497222 0 Td 48.611111 Tz (for ) Tj 1.030556 0 Td 45.640432 Tz (surfactants. ) Tj 3.441667 0 Td 58.333333 Tz (Adequate ) Tj 51.428571 0 0 51.428571 0 2088.172662 Tm 6.377778 0 Td 53.796296 Tz (space ) Tj 1.769444 0 Td 49.583333 Tz (separation ) Tj 3.169444 0 Td 56.712963 Tz (of ) Tj 0.797222 0 Td 49.608262 Tz (nanoparticles ) Tj 4.044444 0 Td 45.37037 Tz (will ) Tj 1.283333 0 Td 52.932099 Tz (ensure ) Tj 2.119444 0 Td 68.518519 Tz (maximum ) Tj 3.052778 0 Td 50.231481 Tz (effi ) Tj 51.428571 0 0 51.428571 0 2045.92233 Tm 6.358333 0 Td 51.851852 Tz (ciency ) Tj 2.119444 0 Td 55.092593 Tz (of ) Tj 0.816667 0 Td 49.109687 Tz (nanoparticles ) Tj 4.044444 0 Td 45.37037 Tz (in ) Tj 0.777778 0 Td 46.090535 Tz (catalysis ) Tj 2.683333 0 Td 59.41358 Tz (and ) Tj 1.263889 0 Td 52.391975 Tz (sensor ) Tj 2.061111 0 Td 47.115385 Tz (applications. ) Tj 51.428571 0 0 51.428571 0 2005.992593 Tm 6.358333 0 Td 52.441077 Tz (Therapeutic ) Tj 3.752778 0 Td 51.311728 Tz (agents ) Tj 2.158333 0 Td 66.975309 Tz (may ) Tj 1.497222 0 Td 58.333333 Tz (be ) Tj 0.952778 0 Td 52.283951 Tz (co-encapsulated ) Tj 4.958333 0 Td 53.472222 Tz (with ) Tj 1.594444 0 Td 60.648148 Tz (nanopar ) Tj 51.428571 0 0 51.428571 0 1960.108462 Tm 6.338889 0 Td 43.209877 Tz (ticles ) Tj 1.711111 0 Td 45.37037 Tz (that ) Tj 1.244444 0 Td 60.277778 Tz (would ) Tj 1.925 0 Td 48.611111 Tz (act ) Tj 1.011111 0 Td 50.231481 Tz (as ) Tj 0.777778 0 Td 50.771605 Tz (radiographic ) Tj 3.811111 0 Td 45.694444 Tz (contrasts. ) Tj 2.877778 0 Td 54.282407 Tz (This ) Tj 1.458333 0 Td 55.902778 Tz (approach ) Tj 51.428571 0 0 51.428571 0 1920.719902 Tm 6.358333 0 Td 69.135802 Tz (may ) Tj 1.438889 0 Td 47.314815 Tz (offer ) Tj 1.555556 0 Td 53.472222 Tz (high ) Tj 1.497222 0 Td 51.851852 Tz (loading ) Tj 2.352778 0 Td 49.826389 Tz (capacity ) Tj 2.605556 0 Td 47.530864 Tz (for ) Tj 1.011111 0 Td 50.636574 Tz (carrying ) Tj 2.586111 0 Td 49.691358 Tz (drugs, ) Tj 2.002778 0 Td 58.333333 Tz (which ) Tj 1.925 0 Td 40.509259 Tz (is ) Tj 51.428571 0 0 51.428571 0 1877.586207 Tm 6.358333 0 Td 52.572016 Tz (important ) Tj 3.072222 0 Td 48.611111 Tz (for ) Tj 1.05 0 Td 47.530864 Tz (either ) Tj 1.905556 0 Td 48.935185 Tz (delivering ) Tj 3.130556 0 Td 54.282407 Tz (high ) Tj 1.555556 0 Td 53.148148 Tz (doses ) Tj 1.847222 0 Td 59.953704 Tz (of ) Tj 0.875 0 Td 53.148148 Tz (medication ) Tj 3.441667 0 Td 51.851852 Tz (or ) Tj 51.428571 0 0 51.428571 0 1834.511085 Tm 6.358333 0 Td 52.256944 Tz (enabling ) Tj 2.625 0 Td 55.092593 Tz (extended ) Tj 2.8 0 Td 44.560185 Tz (release. ) Tj 2.313889 0 Td 50.925926 Tz (Several ) Tj 2.275 0 Td 56.712963 Tz (examples ) Tj 2.877778 0 Td 56.712963 Tz (of ) Tj 0.758333 0 Td 49.109687 Tz (nanorattles' ) Tj 57.142857 0 0 57.142857 0 1793.968867 Tm 5.705 0 Td 51.041667 Tz (have ) Tj 1.4 0 Td 51.770833 Tz (been ) Tj 1.435 0 Td 43.101852 Tz (reported. ) Tj 2.8 0 Td 48.125 Tz (Decreasing ) Tj 3.08 0 Td 44.722222 Tz (the ) Tj 0.98 0 Td 40.833333 Tz (shell ) Tj 1.4 0 Td 45.37037 Tz (thickness ) Tj 2.6075 0 Td 43.75 Tz (in ) Tj 0.6825 0 Td 45.5 Tz (these ) Tj 51.428571 0 0 51.428571 0 1753.66275 Tm 6.338889 0 Td 53.472222 Tz (hybrid ) Tj 2.080556 0 Td 50 Tz (nanostructures ) Tj 4.355556 0 Td 40.509259 Tz (is ) Tj 0.622222 0 Td 52.932099 Tz (important ) Tj 2.994444 0 Td 46.450617 Tz (for ) Tj 0.952778 0 Td 46.018519 Tz (their ) Tj 1.477778 0 Td 46.450617 Tz (practical ) Tj 2.644444 0 Td 56.018519 Tz (applica ) Tj 40 0 0 40 0 1716 Tm 8.15 0 Td 56.944444 Tz (tions. ) Tj 51.428571 0 0 51.428571 0 1669.678981 Tm 7.116667 0 Td 46.990741 Tz (In ) Tj 0.719444 0 Td 53.240741 Tz (another ) Tj 2.352778 0 Td 47.685185 Tz (aspect, ) Tj 2.197222 0 Td 48.611111 Tz (the ) Tj 1.069444 0 Td 49.691358 Tz (invention ) Tj 2.858333 0 Td 51.851852 Tz (provides ) Tj 2.663889 0 Td 51.851852 Tz (a ) Tj 0.525 0 Td 52.5 Tz (metal ) Tj 1.788889 0 Td 60.185185 Tz (nanopar ) Tj 52.857143 0 0 52.857143 0 1629.54 Tm 6.167568 0 Td 41.621622 Tz (ticle ) Tj 1.513514 0 Td 52.202202 Tz (entrapped ) Tj 3.064865 0 Td 53.603604 Tz (or ) Tj 0.908108 0 Td 50.713213 Tz (encapsulated ) Tj 3.954054 0 Td 44.144144 Tz (in ) Tj 0.813514 0 Td 56.756757 Tz (a ) Tj 0.605405 0 Td 57.207207 Tz (polymer ) Tj 2.667568 0 Td 53.030303 Tz (nanocapsule ) Tj 51.428571 0 0 51.428571 0 1585.112628 Tm 6.358333 0 Td 56.712963 Tz (produced ) Tj 2.897222 0 Td 58.333333 Tz (by ) Tj 0.894444 0 Td 56.17284 Tz (any ) Tj 1.244444 0 Td 60.493827 Tz (method ) Tj 2.352778 0 Td 51.851852 Tz (described ) Tj 2.955556 0 Td 47.222222 Tz (herein. ) Tj 51.428571 0 0 51.428571 0 1543.678981 Tm 7.116667 0 Td 46.990741 Tz (In ) Tj 0.719444 0 Td 53.240741 Tz (another ) Tj 2.352778 0 Td 47.685185 Tz (aspect, ) Tj 2.197222 0 Td 48.611111 Tz (the ) Tj 1.069444 0 Td 49.691358 Tz (invention ) Tj 2.858333 0 Td 51.851852 Tz (provides ) Tj 2.663889 0 Td 51.851852 Tz (a ) Tj 0.525 0 Td 52.5 Tz (metal ) Tj 1.788889 0 Td 60.185185 Tz (nanopar ) Tj 51.428571 0 0 51.428571 0 1505.560794 Tm 6.338889 0 Td 42.777778 Tz (ticle ) Tj 1.516667 0 Td 53.652263 Tz (entrapped ) Tj 3.169444 0 Td 53.472222 Tz (or ) Tj 0.875 0 Td 52.121914 Tz (encapsulated ) Tj 4.025 0 Td 45.37037 Tz (in ) Tj 0.816667 0 Td 58.333333 Tz (a ) Tj 0.583333 0 Td 59.259259 Tz (polymer ) Tj 2.761111 0 Td 51.58179 Tz (nanocapsule, ) Tj 51.428571 0 0 51.428571 0 1463.256773 Tm 6.358333 0 Td 48.935185 Tz (optionally ) Tj 3.091667 0 Td 47.685185 Tz (further ) Tj 2.119444 0 Td 54.444444 Tz (comprising ) Tj 3.383333 0 Td 51.311728 Tz (atherapeutic ) Tj 3.85 0 Td 52.5 Tz (agent ) Tj 1.711111 0 Td 39.969136 Tz (\(e.g., ) Tj 1.575 0 Td 58.333333 Tz (a ) Tj 0.486111 0 Td 69.135802 Tz (che ) Tj 51.428571 0 0 51.428571 0 1421.247756 Tm 6.358333 0 Td 53.347578 Tz (motherapeutic ) Tj 4.336111 0 Td 47.685185 Tz (agent\), ) Tj 2.197222 0 Td 48.611111 Tz (for ) Tj 1.030556 0 Td 54.012346 Tz (use ) Tj 1.166667 0 Td 43.75 Tz (in ) Tj 0.719444 0 Td 47.800926 Tz (therapy. ) Tj 51.428571 0 0 51.428571 0 1377.678981 Tm 7.116667 0 Td 46.990741 Tz (In ) Tj 0.719444 0 Td 53.240741 Tz (another ) Tj 2.352778 0 Td 47.685185 Tz (aspect, ) Tj 2.197222 0 Td 48.611111 Tz (the ) Tj 1.069444 0 Td 49.691358 Tz (invention ) Tj 2.858333 0 Td 51.851852 Tz (provides ) Tj 2.663889 0 Td 51.851852 Tz (a ) Tj 0.525 0 Td 52.5 Tz (metal ) Tj 1.788889 0 Td 60.185185 Tz (nanopar ) Tj 51.428571 0 0 51.428571 0 1338.560794 Tm 6.338889 0 Td 42.777778 Tz (ticle ) Tj 1.516667 0 Td 53.652263 Tz (entrapped ) Tj 3.169444 0 Td 53.472222 Tz (or ) Tj 0.875 0 Td 52.121914 Tz (encapsulated ) Tj 4.025 0 Td 45.37037 Tz (in ) Tj 0.816667 0 Td 58.333333 Tz (a ) Tj 0.583333 0 Td 59.259259 Tz (polymer ) Tj 2.761111 0 Td 51.58179 Tz (nanocapsule, ) Tj 51.428571 0 0 51.428571 0 1297.256773 Tm 6.358333 0 Td 48.935185 Tz (optionally ) Tj 3.091667 0 Td 47.685185 Tz (further ) Tj 2.119444 0 Td 54.444444 Tz (comprising ) Tj 3.383333 0 Td 51.311728 Tz (atherapeutic ) Tj 3.85 0 Td 52.5 Tz (agent ) Tj 1.711111 0 Td 39.969136 Tz (\(e.g., ) Tj 1.575 0 Td 58.333333 Tz (a ) Tj 0.486111 0 Td 69.135802 Tz (che ) Tj 51.428571 0 0 51.428571 0 1253.556725 Tm 6.358333 0 Td 53.347578 Tz (motherapeutic ) Tj 4.277778 0 Td 47.685185 Tz (agent\), ) Tj 2.138889 0 Td 47.530864 Tz (for ) Tj 0.933333 0 Td 50.084175 Tz (preparation ) Tj 3.461111 0 Td 51.851852 Tz (of ) Tj 0.680556 0 Td 58.333333 Tz (a ) Tj 0.466667 0 Td 59.305556 Tz (medicament ) Tj 3.655556 0 Td 48.611111 Tz (for ) Tj 0.972222 0 Td 49.691358 Tz (the ) Tj 40 0 0 40 0 1216 Tm 8.15 0 Td 66.203704 Tz (treatment ) Tj 3.825 0 Td 70.833333 Tz (of ) Tj 0.975 0 Td 66.666667 Tz (a ) Tj 0.675 0 Td 64.285714 Tz (disease ) Tj 2.925 0 Td 66.666667 Tz (or ) Tj 1 0 Td 65.277778 Tz (condition ) Tj 3.8 0 Td 69.791667 Tz (Such ) Tj 1.9 0 Td 64.583333 Tz (as ) Tj 1.025 0 Td 61.904762 Tz (cancer. ) Tj 51.428571 0 0 51.428571 0 1169.349306 Tm 7.097222 0 Td 53.796296 Tz (Thus, ) Tj 1.788889 0 Td 48.611111 Tz (for ) Tj 0.991667 0 Td 54.6875 Tz (example, ) Tj 2.838889 0 Td 53.20216 Tz (nanocapsules ) Tj 3.986111 0 Td 55.092593 Tz (can ) Tj 1.147222 0 Td 59.953704 Tz (be ) Tj 0.875 0 Td 55.092593 Tz (used ) Tj 1.458333 0 Td 50.231481 Tz (as ) Tj 0.797222 0 Td 59.143519 Tz (nanoreac ) Tj 51.428571 0 0 51.428571 0 1129.485437 Tm 6.338889 0 Td 42.12963 Tz (tors. ) Tj 1.516667 0 Td 69.675926 Tz (Many ) Tj 1.944444 0 Td 51.851852 Tz (metal ) Tj 1.827778 0 Td 49.109687 Tz (nanoparticles ) Tj 4.063889 0 Td 61.574074 Tz (showed ) Tj 2.411111 0 Td 46.254209 Tz (significant ) Tj 3.286111 0 Td 45.010288 Tz (catalytic ) Tj 51.428571 0 0 51.428571 0 1086.801779 Tm 6.358333 0 Td 42.12963 Tz (activity. ) Tj 2.547222 0 Td 35.648148 Tz (It ) Tj 0.661111 0 Td 38.888889 Tz (is ) Tj 0.680556 0 Td 55.092593 Tz (hard ) Tj 1.516667 0 Td 46.990741 Tz (to ) Tj 0.816667 0 Td 48.070988 Tz (create ) Tj 1.983333 0 Td 45.37037 Tz (catalytic ) Tj 2.683333 0 Td 50.925926 Tz (devices ) Tj 2.372222 0 Td 57.523148 Tz (from ) Tj 1.652778 0 Td 60.648148 Tz (nanopar ) Tj 51.428571 0 0 51.428571 0 1044.47914 Tm 6.338889 0 Td 43.209877 Tz (ticles ) Tj 1.808333 0 Td 55.555556 Tz (because ) Tj 2.605556 0 Td 49.358974 Tz (nanoparticles ) Tj 4.122222 0 Td 52.662037 Tz (tend ) Tj 1.536111 0 Td 48.611111 Tz (to ) Tj 0.816667 0 Td 52.572016 Tz (aggregate ) Tj 3.130556 0 Td 57.253086 Tz (due ) Tj 1.302778 0 Td 45.37037 Tz (to ) Tj 0.816667 0 Td 46.018519 Tz (their ) Tj 51.428571 0 0 51.428571 0 1004.614994 Tm 6.338889 0 Td 54.282407 Tz (high ) Tj 1.652778 0 Td 49.537037 Tz (Surface ) Tj 2.372222 0 Td 51.041667 Tz (area ) Tj 1.516667 0 Td 59.41358 Tz (and ) Tj 1.380556 0 Td 53.347578 Tz (corresponding ) Tj 4.452778 0 Td 53.472222 Tz (high ) Tj 1.613889 0 Td 50 Tz (Surface ) Tj 2.391667 0 Td 49.537037 Tz (energy. ) Tj 51.428571 0 0 51.428571 0 960.896552 Tm 6.358333 0 Td 61.574074 Tz (They ) Tj 1.672222 0 Td 56.712963 Tz (need ) Tj 1.516667 0 Td 43.75 Tz (to ) Tj 0.7 0 Td 58.333333 Tz (be ) Tj 0.875 0 Td 46.342593 Tz (stabilized ) Tj 2.936111 0 Td 59.953704 Tz (by ) Tj 0.894444 0 Td 46.450617 Tz (either ) Tj 1.808333 0 Td 53.324916 Tz (surrounding ) Tj 3.675 0 Td 59.953704 Tz (them ) Tj 1.633333 0 Td 52.662037 Tz (with ) Tj 1.438889 0 Td 55.092593 Tz (a ) Tj 51.428571 0 0 51.428571 0 920.545455 Tm 6.377778 0 Td 47.638889 Tz (Surfactant ) Tj 3.091667 0 Td 52.391975 Tz (matrix ) Tj 2.119444 0 Td 59.953704 Tz (of ) Tj 0.855556 0 Td 58.333333 Tz (by ) Tj 0.933333 0 Td 60.493827 Tz (embedding ) Tj 3.480556 0 Td 60.763889 Tz (them ) Tj 1.730556 0 Td 45.37037 Tz (in ) Tj 0.777778 0 Td 52.932099 Tz (polymers. ) Tj 3.111111 0 Td 64.814815 Tz (As ) Tj 1.030556 0 Td 55.092593 Tz (a ) Tj 51.428571 0 0 51.428571 0 877.910843 Tm 6.358333 0 Td 42.592593 Tz (result, ) Tj 1.963889 0 Td 51.851852 Tz (they ) Tj 1.419444 0 Td 46.990741 Tz (either ) Tj 1.847222 0 Td 49.421296 Tz (lose ) Tj 1.341667 0 Td 66.435185 Tz (much ) Tj 1.75 0 Td 59.953704 Tz (of ) Tj 0.797222 0 Td 46.018519 Tz (their ) Tj 1.516667 0 Td 45.37037 Tz (catalytic ) Tj 2.625 0 Td 45.37037 Tz (activity ) Tj 2.333333 0 Td 52.932099 Tz (and/or ) Tj 51.428571 0 0 51.428571 0 835.853012 Tm 6.377778 0 Td 59.953704 Tz (show ) Tj 1.691667 0 Td 54.282407 Tz (slow ) Tj 1.536111 0 Td 46.720679 Tz (interactions ) Tj 3.538889 0 Td 53.472222 Tz (with ) Tj 1.497222 0 Td 45.37037 Tz (Substrates. ) Tj 3.227778 0 Td 53.472222 Tz (Entrapping ) Tj 3.402778 0 Td 60.648148 Tz (nanopar ) Tj 51.428571 0 0 51.428571 0 796.608158 Tm 6.338889 0 Td 43.209877 Tz (ticles ) Tj 1.788889 0 Td 45.37037 Tz (in ) Tj 0.777778 0 Td 55.092593 Tz (hollow ) Tj 2.294444 0 Td 53.914141 Tz (nanocapsule ) Tj 3.772222 0 Td 55.092593 Tz (keeps ) Tj 1.886111 0 Td 49.691358 Tz (the ) Tj 1.166667 0 Td 56.388889 Tz (naked ) Tj 1.944444 0 Td 49.358974 Tz (nanoparticles ) Tj 51.428571 0 0 51.428571 0 754.792128 Tm 6.358333 0 Td 47.962963 Tz (apart ) Tj 1.633333 0 Td 59.41358 Tz (and ) Tj 1.225 0 Td 52.256944 Tz (provides ) Tj 2.702778 0 Td 58.873457 Tz (enough ) Tj 2.333333 0 Td 59.62963 Tz (empty ) Tj 2.002778 0 Td 53.796296 Tz (space ) Tj 1.788889 0 Td 56.712963 Tz (around ) Tj 2.197222 0 Td 60.763889 Tz (them ) Tj 1.672222 0 Td 48.611111 Tz (for ) Tj 1.030556 0 Td 49.691358 Tz (the ) Tj 51.428571 0 0 51.428571 0 711.502283 Tm 6.358333 0 Td 51.851852 Tz (flow ) Tj 1.458333 0 Td 58.333333 Tz (of ) Tj 0.816667 0 Td 47.314815 Tz (substrates ) Tj 3.013889 0 Td 59.41358 Tz (and ) Tj 1.244444 0 Td 49.331276 Tz (products. ) Tj 51.428571 0 0 51.428571 0 670.699164 Tm 7.097222 0 Td 66.435185 Tz (As ) Tj 1.147222 0 Td 52.314815 Tz (another ) Tj 2.527778 0 Td 54.6875 Tz (example, ) Tj 2.975 0 Td 49.691358 Tz (the ) Tj 1.263889 0 Td 53.20216 Tz (nanocapsules ) Tj 4.2 0 Td 55.092593 Tz (can ) Tj 1.341667 0 Td 58.333333 Tz (be ) Tj 1.05 0 Td 55.092593 Tz (used ) Tj 1.652778 0 Td 50.231481 Tz (in ) Tj 51.428571 0 0 51.428571 0 629.118963 Tm 6.358333 0 Td 51.58179 Tz (nanosensors. ) Tj 3.869444 0 Td 48.611111 Tz (Silver ) Tj 1.905556 0 Td 49.109687 Tz (nanoparticles ) Tj 3.966667 0 Td 56.712963 Tz (have ) Tj 1.458333 0 Td 57.523148 Tz (been ) Tj 1.516667 0 Td 55.902778 Tz (used ) Tj 1.497222 0 Td 43.75 Tz (in ) Tj 0.641667 0 Td 54.282407 Tz (recently ) Tj 51.428571 0 0 51.428571 0 586.533643 Tm 6.358333 0 Td 59.259259 Tz (emerged ) Tj 2.644444 0 Td 52.864583 Tz (surface-enhanced ) Tj 5.172222 0 Td 60.925926 Tz (raman ) Tj 1.983333 0 Td 46.990741 Tz (scattering ) Tj 2.955556 0 Td 62.114198 Tz (\(SERS\) ) Tj 2.372222 0 Td 55.092593 Tz (method. ) Tj 51.428571 0 0 51.428571 0 545.02267 Tm 6.358333 0 Td 54.768519 Tz (Adsorption ) Tj 3.538889 0 Td 58.333333 Tz (of ) Tj 0.894444 0 Td 54.012346 Tz (molecules ) Tj 3.227778 0 Td 56.712963 Tz (on ) Tj 0.952778 0 Td 50.771605 Tz (the ) Tj 1.186111 0 Td 49.537037 Tz (Surface ) Tj 2.372222 0 Td 56.712963 Tz (of ) Tj 0.855556 0 Td 45.37037 Tz (silver ) Tj 1.886111 0 Td 60.648148 Tz (nanopar ) Tj 51.428571 0 0 51.428571 0 503.0882 Tm 6.338889 0 Td 43.209877 Tz (ticles ) Tj 1.711111 0 Td 45.37037 Tz (result ) Tj 1.808333 0 Td 43.75 Tz (in ) Tj 0.719444 0 Td 52.662037 Tz (dramatic ) Tj 2.722222 0 Td 47.530864 Tz (signal ) Tj 1.847222 0 Td 56.17284 Tz (enhancement, ) Tj 4.2 0 Td 53.06713 Tz (allowing ) Tj 2.702778 0 Td 58.981481 Tz (detec ) Tj 51.428571 0 0 51.428571 0 463.328963 Tm 6.338889 0 Td 47.800926 Tz (tion ) Tj 1.283333 0 Td 55.092593 Tz (of ) Tj 0.738889 0 Td 53.472222 Tz (very ) Tj 1.419444 0 Td 51.851852 Tz (small ) Tj 1.672222 0 Td 58.796296 Tz (amounts ) Tj 2.625 0 Td 55.092593 Tz (of ) Tj 0.738889 0 Td 46.8107 Tz (analytes. ) Tj 2.663889 0 Td 52.662037 Tz (Analysis ) Tj 2.663889 0 Td 55.092593 Tz (of ) Tj 0.738889 0 Td 55.092593 Tz (a ) Tj 0.466667 0 Td 59.259259 Tz (complex ) Tj 51.428571 0 0 51.428571 0 420.831943 Tm 6.358333 0 Td 54.166667 Tz (mixture ) Tj 2.45 0 Td 37.268519 Tz (is ) Tj 0.641667 0 Td 53.914141 Tz (complicated ) Tj 3.694444 0 Td 52.777778 Tz (though, ) Tj 2.372222 0 Td 55.555556 Tz (because ) Tj 2.488889 0 Td 39.969136 Tz (all ) Tj 0.913889 0 Td 54.012346 Tz (molecules ) Tj 3.091667 0 Td 61.574074 Tz (would ) Tj 51.428571 0 0 51.428571 0 380.271663 Tm 6.338889 0 Td 57.523148 Tz (have ) Tj 1.477778 0 Td 51.131687 Tz (increased ) Tj 2.858333 0 Td 45.37037 Tz (signals. ) Tj 2.352778 0 Td 38.888889 Tz (If ) Tj 0.544444 0 Td 45.910494 Tz (silver ) Tj 1.769444 0 Td 49.109687 Tz (nanoparticles ) Tj 3.947222 0 Td 49.691358 Tz (are ) Tj 1.011111 0 Td 52.932099 Tz (entrapped ) Tj 2.975 0 Td 48.611111 Tz (in ) Tj 51.428571 0 0 51.428571 0 338.55 Tm 6.358333 0 Td 53.742284 Tz (nanocapsules ) Tj 4.2 0 Td 52.662037 Tz (with ) Tj 1.594444 0 Td 46.450617 Tz (selective ) Tj 2.780556 0 Td 48.611111 Tz (pores, ) Tj 2.061111 0 Td 53.472222 Tz (only ) Tj 1.594444 0 Td 46.759259 Tz (certain ) Tj 2.313889 0 Td 54.012346 Tz (molecules ) Tj 51.428571 0 0 51.428571 0 295.990196 Tm 6.338889 0 Td 61.574074 Tz (would ) Tj 2.002778 0 Td 54.012346 Tz (adsorb ) Tj 2.158333 0 Td 59.953704 Tz (on ) Tj 0.933333 0 Td 48.611111 Tz (the ) Tj 1.108333 0 Td 47.685185 Tz (nanoparticles. ) Tj 4.180556 0 Td 54.282407 Tz (This ) Tj 1.536111 0 Td 58.981481 Tz (would ) Tj 1.963889 0 Td 53.472222 Tz (permit ) Tj 2.138889 0 Td 61.574074 Tz (more ) Tj 51.428571 0 0 51.428571 0 252.93765 Tm 6.358333 0 Td 50.636574 Tz (accurate ) Tj 2.683333 0 Td 56.983025 Tz (measurements ) Tj 4.316667 0 Td 58.333333 Tz (of ) Tj 0.816667 0 Td 52.5 Tz (Small ) Tj 1.808333 0 Td 54.372428 Tz (molecules ) Tj 3.15 0 Td 45.37037 Tz (in ) Tj 0.758333 0 Td 50.356125 Tz (physiological ) Tj 51.428571 0 0 51.428571 0 212.020942 Tm 6.358333 0 Td 44.830247 Tz (fluids ) Tj 1.944444 0 Td 47.800926 Tz (\(blood\), ) Tj 2.625 0 Td 58.981481 Tz (where ) Tj 2.1 0 Td 47.314815 Tz (large ) Tj 1.769444 0 Td 53.652263 Tz (molecules ) Tj 3.227778 0 Td 54.282407 Tz (such ) Tj 1.613889 0 Td 50.231481 Tz (as ) Tj 0.933333 0 Td 48.611111 Tz (proteins ) Tj 2.663889 0 Td 51.851852 Tz (or ) Tj 51.428571 0 0 51.428571 0 170.990769 Tm 6.377778 0 Td 85.339506 Tz (DNA ) Tj 1.711111 0 Td 60.925926 Tz (would ) Tj 2.002778 0 Td 56.712963 Tz (be ) Tj 0.875 0 Td 42.939815 Tz (filtered ) Tj 2.236111 0 Td 51.851852 Tz (out ) Tj 1.108333 0 Td 59.953704 Tz (by ) Tj 0.933333 0 Td 48.611111 Tz (the ) Tj 1.069444 0 Td 51.353276 Tz (nanocapsules. ) Tj 30 0 0 30 0 2547 Tm 41.666667 0 Td 75 Tz (10 ) Tj 30 0 0 30 0 2339 Tm 41.666667 0 Td 72.222222 Tz (15 ) Tj 30 0 0 30 0 1923 Tm 41.6 0 Td 77.777778 Tz (25 ) Tj 30 0 0 30 0 1716 Tm 41.6 0 Td 80.555556 Tz (30 ) Tj 30 0 0 30 0 1507 Tm 41.6 0 Td 77.777778 Tz (35 ) Tj 30 0 0 30 0 1299 Tm 41.566667 0 Td 83.333333 Tz (40 ) Tj 30 0 0 30 0 1091 Tm 41.566667 0 Td 80.555556 Tz (45 ) Tj 30 0 0 30 0 883 Tm 41.6 0 Td 80.555556 Tz (50 ) Tj 30 0 0 30 0 675 Tm 41.6 0 Td 77.777778 Tz (55 ) Tj 30 0 0 30 0 467 Tm 41.633333 0 Td 77.777778 Tz (60 ) Tj 30 0 0 30 0 259 Tm 41.633333 0 Td 75 Tz (65 ) Tj 51.428571 0 0 51.428571 0 2969 Tm 33.775 0 Td 77.777778 Tz (4 ) Tj 51.428571 0 0 51.428571 0 2919.299371 Tm 26.016667 0 Td 56.17284 Tz (Nanocapsules ) Tj 4.258333 0 Td 51.851852 Tz (entrapping ) Tj 3.325 0 Td 53.148148 Tz (metal ) Tj 1.827778 0 Td 49.358974 Tz (nanoparticles ) Tj 4.083333 0 Td 54.012346 Tz (can ) Tj 1.166667 0 Td 59.953704 Tz (be ) Tj 0.913889 0 Td 64.814815 Tz (pre ) Tj 51.428571 0 0 51.428571 0 2872.934726 Tm 25.297222 0 Td 49.691358 Tz (pared, ) Tj 2.061111 0 Td 41.481481 Tz (e.g., ) Tj 1.497222 0 Td 51.851852 Tz (as ) Tj 0.913889 0 Td 51.49177 Tz (described ) Tj 3.033333 0 Td 47.222222 Tz (herein. ) Tj 2.333333 0 Td 57.523148 Tz (Here ) Tj 1.652778 0 Td 71.296296 Tz (we ) Tj 1.127778 0 Td 60.763889 Tz (show ) Tj 1.769444 0 Td 58.333333 Tz (a ) Tj 0.622222 0 Td 50.636574 Tz (one-step ) Tj 51.428571 0 0 51.428571 0 2831.273159 Tm 25.316667 0 Td 48.971193 Tz (synthesis ) Tj 2.8 0 Td 56.712963 Tz (of ) Tj 0.758333 0 Td 55.092593 Tz (hollow ) Tj 2.158333 0 Td 58.796296 Tz (polymer ) Tj 2.625 0 Td 53.472222 Tz (nanocapsules ) Tj 4.025 0 Td 45.37037 Tz (that ) Tj 1.225 0 Td 50.771605 Tz (entrap ) Tj 2.022222 0 Td 60.925926 Tz (simul ) Tj 51.428571 0 0 51.428571 0 2786.820633 Tm 25.277778 0 Td 51.851852 Tz (taneously ) Tj 2.955556 0 Td 57.79321 Tz (formed ) Tj 2.197222 0 Td 45.37037 Tz (silver ) Tj 1.769444 0 Td 47.314815 Tz (nano-particles. ) Tj 4.355556 0 Td 79.398148 Tz (We ) Tj 1.088889 0 Td 55.092593 Tz (used ) Tj 1.438889 0 Td 54.372428 Tz (liposomes ) Tj 3.072222 0 Td 50.231481 Tz (as ) Tj 51.428571 0 0 51.428571 0 2740.384615 Tm 25.277778 0 Td 50.771605 Tz (the ) Tj 1.088889 0 Td 48.206019 Tz (scaffold ) Tj 2.508333 0 Td 49.691358 Tz (for ) Tj 1.05 0 Td 49.691358 Tz (the ) Tj 1.088889 0 Td 48.611111 Tz (synthesis ) Tj 2.838889 0 Td 51.851852 Tz (\(FIG. ) Tj 1.808333 0 Td 39.969136 Tz (1\). ) Tj 0.952778 0 Td 54.282407 Tz (FIG. ) Tj 1.555556 0 Td 48.611111 Tz (1 ) Tj 0.505556 0 Td 37.268519 Tz (is ) Tj 0.641667 0 Td 55.092593 Tz (a ) Tj 0.544444 0 Td 53.292181 Tz (schematic ) Tj 51.428571 0 0 51.428571 0 2702.022327 Tm 25.297222 0 Td 50.05144 Tz (depiction ) Tj 2.838889 0 Td 55.092593 Tz (of ) Tj 0.738889 0 Td 58.333333 Tz (a ) Tj 0.486111 0 Td 48.611111 Tz (synthesis ) Tj 2.8 0 Td 55.092593 Tz (of ) Tj 0.719444 0 Td 58.333333 Tz (a ) Tj 0.447222 0 Td 59.259259 Tz (polymer ) Tj 2.605556 0 Td 54.208754 Tz (nanocapsule ) Tj 3.694444 0 Td 52.175926 Tz (entrapping ) Tj 51.428571 0 0 51.428571 0 2656.702422 Tm 25.316667 0 Td 44.830247 Tz (silver ) Tj 1.788889 0 Td 47.685185 Tz (nanoparticles. ) Tj 51.428571 0 0 51.428571 0 2611.549215 Tm 26.036111 0 Td 48.611111 Tz (In ) Tj 1.127778 0 Td 46.296296 Tz (certain ) Tj 2.45 0 Td 57.253086 Tz (embodiments, ) Tj 4.647222 0 Td 55.092593 Tz (a ) Tj 0.816667 0 Td 58.796296 Tz (polymer ) Tj 2.975 0 Td 54.208754 Tz (nanocapsule ) Tj 4.102778 0 Td 50.231481 Tz (as ) Tj 48.571429 0 0 48.571429 0 2566 Tm 26.785294 0 Td 54.901961 Tz (described ) Tj 3.108824 0 Td 53.75817 Tz (herein ) Tj 2.161765 0 Td 39.460784 Tz (is ) Tj 0.658824 0 Td 58.333333 Tz (about ) Tj 1.914706 0 Td 66.911765 Tz (40 ) Tj 1.008824 0 Td 77.205882 Tz (nm ) Tj 1.132353 0 Td 48.039216 Tz (to ) Tj 0.782353 0 Td 57.647059 Tz (about ) Tj 1.914706 0 Td 65.196078 Tz (50 ) Tj 0.988235 0 Td 57.843137 Tz (microns ) Tj 2.614706 0 Td 49.754902 Tz (in ) Tj 0.823529 0 Td 45.294118 Tz (size; ) Tj 48.571429 0 0 48.571429 0 2522 Tm 26.785294 0 Td 48.039216 Tz (in ) Tj 0.741176 0 Td 50 Tz (certain ) Tj 2.264706 0 Td 60.620915 Tz (embodiments, ) Tj 4.55 0 Td 60.906863 Tz (from ) Tj 1.626471 0 Td 57.647059 Tz (about ) Tj 1.873529 0 Td 66.911765 Tz (40 ) Tj 0.988235 0 Td 77.205882 Tz (nm ) Tj 1.111765 0 Td 49.754902 Tz (to ) Tj 0.761765 0 Td 57.647059 Tz (about ) Tj 1.955882 0 Td 61.764706 Tz (1000 ) Tj 1.647059 0 Td 54.901961 Tz (nm. ) Tj 48.571429 0 0 48.571429 0 2479 Tm 26.785294 0 Td 48.039216 Tz (in ) Tj 0.823529 0 Td 45.980392 Tz (size; ) Tj 1.647059 0 Td 46.323529 Tz (in ) Tj 0.782353 0 Td 49.509804 Tz (certain ) Tj 2.326471 0 Td 60.04902 Tz (embodiments, ) Tj 4.55 0 Td 61.764706 Tz (from ) Tj 1.708824 0 Td 57.647059 Tz (about ) Tj 1.935294 0 Td 66.911765 Tz (40 ) Tj 1.029412 0 Td 77.205882 Tz (nm ) Tj 1.173529 0 Td 48.039216 Tz (to ) Tj 0.782353 0 Td 58.333333 Tz (about ) Tj 48.571429 0 0 48.571429 0 2435 Tm 26.785294 0 Td 64.052288 Tz (250 ) Tj 1.338235 0 Td 77.205882 Tz (nm ) Tj 1.091176 0 Td 48.039216 Tz (in ) Tj 0.741176 0 Td 45.294118 Tz (size; ) Tj 1.544118 0 Td 43.464052 Tz (or, ) Tj 0.947059 0 Td 48.039216 Tz (in ) Tj 0.741176 0 Td 49.019608 Tz (certain ) Tj 2.223529 0 Td 60.334967 Tz (embodiments, ) Tj 4.488235 0 Td 60.906863 Tz (from ) Tj 1.626471 0 Td 57.647059 Tz (about ) Tj 1.832353 0 Td 66.911765 Tz (40 ) Tj 0.947059 0 Td 54.901961 Tz (nm. ) Tj 51.428571 0 0 51.428571 0 2390.997478 Tm 25.277778 0 Td 45.37037 Tz (to ) Tj 0.738889 0 Td 55.092593 Tz (about ) Tj 1.866667 0 Td 58.333333 Tz (120 ) Tj 1.244444 0 Td 72.916667 Tz (nm ) Tj 1.069444 0 Td 46.990741 Tz (in ) Tj 0.719444 0 Td 43.425926 Tz (size. ) Tj 1.458333 0 Td 64.814815 Tz (The ) Tj 1.341667 0 Td 46.990741 Tz (size ) Tj 1.283333 0 Td 58.333333 Tz (of ) Tj 0.777778 0 Td 49.691358 Tz (the ) Tj 1.108333 0 Td 49.358974 Tz (nanoparticles ) Tj 4.005556 0 Td 55.092593 Tz (can ) Tj 1.186111 0 Td 58.333333 Tz (be ) Tj 51.428571 0 0 51.428571 0 2350.231293 Tm 25.297222 0 Td 50.231481 Tz (varied ) Tj 1.963889 0 Td 61.574074 Tz (by ) Tj 0.952778 0 Td 55.092593 Tz (changing ) Tj 2.8 0 Td 50.771605 Tz (the ) Tj 1.108333 0 Td 55.497685 Tz (liposome ) Tj 2.838889 0 Td 49.331276 Tz (diameter. ) Tj 51.428571 0 0 51.428571 0 2305.260813 Tm 26.016667 0 Td 63.734568 Tz (The ) Tj 1.419444 0 Td 58.333333 Tz (polymer ) Tj 2.722222 0 Td 54.503367 Tz (nanocapsule ) Tj 3.869444 0 Td 50.231481 Tz (as ) Tj 0.894444 0 Td 51.851852 Tz (described ) Tj 3.052778 0 Td 51.311728 Tz (herein ) Tj 2.119444 0 Td 48.611111 Tz (defines ) Tj 2.333333 0 Td 58.333333 Tz (a ) Tj 51.428571 0 0 51.428571 0 2260.338462 Tm 25.316667 0 Td 44.722222 Tz (shell ) Tj 1.633333 0 Td 51.851852 Tz (or ) Tj 0.855556 0 Td 51.041667 Tz (wall ) Tj 1.497222 0 Td 51.851852 Tz (enclosing ) Tj 3.033333 0 Td 58.333333 Tz (a ) Tj 0.583333 0 Td 55.632716 Tz (hollow ) Tj 2.275 0 Td 45.37037 Tz (interior ) Tj 2.391667 0 Td 54.444444 Tz (space ) Tj 1.886111 0 Td 55.092593 Tz (\(which ) Tj 2.275 0 Td 57.253086 Tz (can ) Tj 51.428571 0 0 51.428571 0 2217.512821 Tm 25.297222 0 Td 61.279461 Tz (accommodate ) Tj 4.336111 0 Td 55.092593 Tz (a ) Tj 0.622222 0 Td 53.148148 Tz (metal ) Tj 1.925 0 Td 49.421296 Tz (nanoparticle ) Tj 3.830556 0 Td 59.41358 Tz (and ) Tj 1.4 0 Td 66.975309 Tz (may ) Tj 1.477778 0 Td 61.574074 Tz (be ) Tj 0.991667 0 Td 44.074074 Tz (filed ) Tj 1.594444 0 Td 54.282407 Tz (with ) Tj 51.428571 0 0 51.428571 0 2172.116279 Tm 25.316667 0 Td 49.537037 Tz (solvent ) Tj 2.352778 0 Td 58.333333 Tz (and ) Tj 1.361111 0 Td 49.691358 Tz (the ) Tj 1.205556 0 Td 41.049383 Tz (like\). ) Tj 1.788889 0 Td 62.654321 Tz (The ) Tj 1.438889 0 Td 45.37037 Tz (shell ) Tj 1.633333 0 Td 55.092593 Tz (or ) Tj 0.933333 0 Td 51.041667 Tz (wall ) Tj 1.555556 0 Td 55.092593 Tz (can ) Tj 1.283333 0 Td 59.953704 Tz (be ) Tj 0.991667 0 Td 55.092593 Tz (porous ) Tj 2.294444 0 Td 53.472222 Tz (or ) Tj 51.428571 0 0 51.428571 0 2131.130982 Tm 25.297222 0 Td 53.472222 Tz (permeable; ) Tj 3.441667 0 Td 49.691358 Tz (the ) Tj 1.108333 0 Td 46.990741 Tz (size ) Tj 1.341667 0 Td 56.712963 Tz (of ) Tj 0.777778 0 Td 58.333333 Tz (any ) Tj 1.263889 0 Td 52.5 Tz (pores ) Tj 1.808333 0 Td 54.012346 Tz (should ) Tj 2.119444 0 Td 58.333333 Tz (be ) Tj 0.894444 0 Td 52.5 Tz (small ) Tj 1.788889 0 Td 59.41358 Tz (enough ) Tj 2.352778 0 Td 45.37037 Tz (to ) Tj 51.428571 0 0 51.428571 0 2086.909091 Tm 25.297222 0 Td 45.37037 Tz (retain ) Tj 1.808333 0 Td 50.771605 Tz (the ) Tj 1.108333 0 Td 52.5 Tz (metal ) Tj 1.769444 0 Td 49.421296 Tz (nanoparticle ) Tj 3.772222 0 Td 35.648148 Tz (\(i.e., ) Tj 1.438889 0 Td 46.990741 Tz (to ) Tj 0.719444 0 Td 52.314815 Tz (prevent ) Tj 2.352778 0 Td 49.691358 Tz (the ) Tj 1.069444 0 Td 53.148148 Tz (metal ) Tj 1.808333 0 Td 67.24537 Tz (nano ) Tj 51.428571 0 0 51.428571 0 2044.195122 Tm 25.297222 0 Td 45.775463 Tz (particle ) Tj 2.372222 0 Td 57.523148 Tz (from ) Tj 1.575 0 Td 52.314815 Tz (passing ) Tj 2.391667 0 Td 50.771605 Tz (out ) Tj 1.108333 0 Td 55.092593 Tz (of ) Tj 0.758333 0 Td 49.691358 Tz (the ) Tj 1.088889 0 Td 44.965278 Tz (interior ) Tj 2.313889 0 Td 56.712963 Tz (of ) Tj 0.777778 0 Td 49.691358 Tz (the ) Tj 1.088889 0 Td 50.854701 Tz (nanocapsule\). ) Tj 51.428571 0 0 51.428571 0 1999.089392 Tm 25.277778 0 Td 52.932099 Tz (but ) Tj 1.069444 0 Td 55.092593 Tz (can ) Tj 1.108333 0 Td 58.333333 Tz (be ) Tj 0.836111 0 Td 47.314815 Tz (large ) Tj 1.536111 0 Td 59.41358 Tz (enough ) Tj 2.236111 0 Td 48.611111 Tz (to ) Tj 0.7 0 Td 53.148148 Tz (allow ) Tj 1.730556 0 Td 43.930041 Tz (efficient ) Tj 2.488889 0 Td 57.118056 Tz (exchange ) Tj 2.858333 0 Td 55.092593 Tz (of ) Tj 0.738889 0 Td 44.965278 Tz (solutes, ) Tj 51.428571 0 0 51.428571 0 1956.178615 Tm 25.297222 0 Td 48.251029 Tz (reagents, ) Tj 2.819444 0 Td 45.959596 Tz (Substrates, ) Tj 3.247222 0 Td 47.530864 Tz (analytes, ) Tj 2.780556 0 Td 51.851852 Tz (or ) Tj 0.797222 0 Td 51.203704 Tz (other ) Tj 1.730556 0 Td 51.851852 Tz (Small ) Tj 1.808333 0 Td 53.652263 Tz (molecular ) Tj 3.091667 0 Td 65.895062 Tz (spe ) Tj 51.428571 0 0 51.428571 0 1910.519497 Tm 25.297222 0 Td 46.990741 Tz (cies ) Tj 1.341667 0 Td 45.37037 Tz (to ) Tj 0.738889 0 Td 51.851852 Tz (pass ) Tj 1.458333 0 Td 50.231481 Tz (across ) Tj 2.041667 0 Td 48.611111 Tz (the ) Tj 1.088889 0 Td 50.231481 Tz (wall ) Tj 1.419444 0 Td 57.407407 Tz (between ) Tj 2.605556 0 Td 50.771605 Tz (the ) Tj 1.088889 0 Td 54.282407 Tz (bulk ) Tj 1.477778 0 Td 48.611111 Tz (solution ) Tj 2.527778 0 Td 56.388889 Tz (phase ) Tj 51.428571 0 0 51.428571 0 1870.397605 Tm 25.297222 0 Td 58.333333 Tz (and ) Tj 1.205556 0 Td 50.771605 Tz (the ) Tj 1.088889 0 Td 44.965278 Tz (interior ) Tj 2.313889 0 Td 56.712963 Tz (of ) Tj 0.777778 0 Td 49.691358 Tz (the ) Tj 1.069444 0 Td 51.851852 Tz (nanocapsule. ) Tj 3.966667 0 Td 50.898693 Tz (Bilayer-templated ) Tj 5.425 0 Td 67.24537 Tz (nano ) Tj 51.428571 0 0 51.428571 0 1827.062802 Tm 25.297222 0 Td 51.041667 Tz (capsules ) Tj 2.663889 0 Td 54.012346 Tz (can ) Tj 1.147222 0 Td 59.953704 Tz (be ) Tj 0.894444 0 Td 52.572016 Tz (imprinted ) Tj 3.033333 0 Td 52.662037 Tz (with ) Tj 1.497222 0 Td 54.372428 Tz (nanopores ) Tj 3.130556 0 Td 54.552469 Tz (having ) Tj 2.158333 0 Td 49.259259 Tz (controlled ) Tj 58.571429 0 0 58.571429 0 1779.256068 Tm 22.229268 0 Td 37.560976 Tz (size, ) Tj 1.280488 0 Td 40.904472 Tz (density, ) Tj 2.1 0 Td 53.116531 Tz (and ) Tj 1.109756 0 Td 47.662602 Tz (chemical ) Tj 2.441463 0 Td 46.714092 Tz (environment. ) Tj 3.773171 0 Td 49.006323 Tz (Formation ) Tj 2.8 0 Td 49.796748 Tz (of ) Tj 0.682927 0 Td 62.601626 Tz (nan ) Tj 51.428571 0 0 51.428571 0 1740.416342 Tm 25.297222 0 Td 53.472222 Tz (opores ) Tj 2.255556 0 Td 38.888889 Tz (is ) Tj 0.777778 0 Td 59.953704 Tz (done ) Tj 1.75 0 Td 51.851852 Tz (using ) Tj 1.866667 0 Td 54.012346 Tz (pore-forming ) Tj 4.180556 0 Td 51.49177 Tz (templates ) Tj 3.111111 0 Td 46.180556 Tz (that ) Tj 1.4 0 Td 49.691358 Tz (are ) Tj 1.186111 0 Td 77.777778 Tz (co ) Tj 51.428571 0 0 51.428571 0 1692.014493 Tm 25.297222 0 Td 50.771605 Tz (dissolved ) Tj 2.916667 0 Td 52.662037 Tz (with ) Tj 1.458333 0 Td 63.599537 Tz (monomers ) Tj 3.247222 0 Td 49.691358 Tz (within ) Tj 2.002778 0 Td 49.691358 Tz (the ) Tj 1.05 0 Td 48.611111 Tz (bilayer ) Tj 2.197222 0 Td 44.965278 Tz (interior ) Tj 2.275 0 Td 59.41358 Tz (and ) Tj 1.244444 0 Td 45.37037 Tz (that ) Tj 60 0 0 60 0 1650.026316 Tm 21.683333 0 Td 42.592593 Tz (are ) Tj 0.916667 0 Td 51.984127 Tz (removed ) Tj 2.3 0 Td 40 Tz (after ) Tj 1.333333 0 Td 41.666667 Tz (the ) Tj 0.866667 0 Td 44.074074 Tz (polymerization. ) Tj 51.428571 0 0 51.428571 0 1606.066339 Tm 26.036111 0 Td 48.611111 Tz (In ) Tj 0.719444 0 Td 46.759259 Tz (certain ) Tj 2.1 0 Td 56.983025 Tz (embodiments, ) Tj 4.238889 0 Td 50.771605 Tz (the ) Tj 1.011111 0 Td 58.796296 Tz (polymer ) Tj 2.586111 0 Td 54.503367 Tz (nanocapsule ) Tj 3.713889 0 Td 40.509259 Tz (is ) Tj 0.641667 0 Td 57.037037 Tz (cross ) Tj 51.428571 0 0 51.428571 0 1562.230955 Tm 25.297222 0 Td 46.759259 Tz (linked. ) Tj 2.138889 0 Td 64.814815 Tz (The ) Tj 1.322222 0 Td 54.012346 Tz (degree ) Tj 2.1 0 Td 55.092593 Tz (of ) Tj 0.719444 0 Td 49.358974 Tz (cross-linking ) Tj 4.005556 0 Td 55.092593 Tz (can ) Tj 1.147222 0 Td 59.953704 Tz (be ) Tj 0.894444 0 Td 49.691358 Tz (varied ) Tj 1.944444 0 Td 58.333333 Tz (by ) Tj 0.894444 0 Td 54.62963 Tz (control ) Tj 51.428571 0 0 51.428571 0 1515.585859 Tm 25.297222 0 Td 46.990741 Tz (ling ) Tj 1.361111 0 Td 49.691358 Tz (the ) Tj 1.127778 0 Td 50.356125 Tz (concentration ) Tj 4.2 0 Td 56.712963 Tz (of ) Tj 0.797222 0 Td 50.771605 Tz (the ) Tj 1.166667 0 Td 65.740741 Tz (monomer ) Tj 3.013889 0 Td 50.231481 Tz (or ) Tj 0.836111 0 Td 63.194444 Tz (monomers ) Tj 3.286111 0 Td 45.37037 Tz (in ) Tj 0.777778 0 Td 50.771605 Tz (the ) Tj 51.428571 0 0 51.428571 0 1473.680751 Tm 25.297222 0 Td 44.074074 Tz (lipid ) Tj 1.458333 0 Td 44.965278 Tz (bilayer, ) Tj 2.275 0 Td 49.691358 Tz (the ) Tj 0.991667 0 Td 51.103989 Tz (concentration ) Tj 4.083333 0 Td 55.092593 Tz (of ) Tj 0.738889 0 Td 48.611111 Tz (the ) Tj 0.991667 0 Td 46.450617 Tz (free-radical ) Tj 3.480556 0 Td 40.509259 Tz (initiator, ) Tj 2.566667 0 Td 49.691358 Tz (the ) Tj 51.428571 0 0 51.428571 0 1433.08642 Tm 25.297222 0 Td 50.231481 Tz (length ) Tj 2.080556 0 Td 58.333333 Tz (of ) Tj 0.855556 0 Td 54.282407 Tz (time ) Tj 1.555556 0 Td 50.771605 Tz (the ) Tj 1.166667 0 Td 48.611111 Tz (cross-linking ) Tj 4.025 0 Td 52.546296 Tz (polymerization ) Tj 4.686111 0 Td 48.611111 Tz (reaction ) Tj 2.605556 0 Td 40.509259 Tz (is ) Tj 51.428571 0 0 51.428571 0 1387.811912 Tm 25.297222 0 Td 54.73251 Tz (perfumed, ) Tj 3.130556 0 Td 59.41358 Tz (and ) Tj 1.244444 0 Td 51.851852 Tz (the ) Tj 1.069444 0 Td 41.481481 Tz (like. ) Tj 51.428571 0 0 51.428571 0 1344.345455 Tm 26.036111 0 Td 50.231481 Tz (In ) Tj 0.7 0 Td 46.759259 Tz (certain ) Tj 2.1 0 Td 56.983025 Tz (embodiments, ) Tj 4.2 0 Td 58.333333 Tz (a ) Tj 0.466667 0 Td 48.206019 Tz (metallic ) Tj 2.469444 0 Td 49.421296 Tz (nanoparticle ) Tj 3.675 0 Td 52.5 Tz (\(entrapped ) Tj 51.428571 0 0 51.428571 0 1301.614232 Tm 25.297222 0 Td 45.37037 Tz (in ) Tj 0.777778 0 Td 58.333333 Tz (a ) Tj 0.583333 0 Td 58.796296 Tz (polymer ) Tj 2.702778 0 Td 52.662037 Tz (nanocapsule\) ) Tj 4.025 0 Td 50.231481 Tz (as ) Tj 0.875 0 Td 51.49177 Tz (described ) Tj 2.994444 0 Td 51.311728 Tz (herein ) Tj 2.080556 0 Td 38.888889 Tz (is ) Tj 0.719444 0 Td 50.411523 Tz (generally ) Tj 51.428571 0 0 51.428571 0 1254.462366 Tm 25.297222 0 Td 58.333333 Tz (from ) Tj 1.652778 0 Td 54.444444 Tz (about ) Tj 1.866667 0 Td 48.611111 Tz (0.5 ) Tj 1.147222 0 Td 74.537037 Tz (nm ) Tj 1.147222 0 Td 45.37037 Tz (to ) Tj 0.777778 0 Td 55.092593 Tz (about ) Tj 1.905556 0 Td 59.953704 Tz (50 ) Tj 0.952778 0 Td 74.537037 Tz (nm ) Tj 1.147222 0 Td 46.990741 Tz (in ) Tj 0.836111 0 Td 46.180556 Tz (size ) Tj 1.341667 0 Td 52.932099 Tz (\(on ) Tj 1.205556 0 Td 48.971193 Tz (average\); ) Tj 2.916667 0 Td 48.611111 Tz (in ) Tj 48.571429 0 0 48.571429 0 1212 Tm 26.785294 0 Td 49.509804 Tz (certain ) Tj 2.223529 0 Td 60.334967 Tz (embodiments, ) Tj 4.488235 0 Td 60.906863 Tz (from ) Tj 1.585294 0 Td 58.333333 Tz (about ) Tj 1.914706 0 Td 41.176471 Tz (1 ) Tj 0.494118 0 Td 77.205882 Tz (nm ) Tj 1.070588 0 Td 49.754902 Tz (to ) Tj 0.7 0 Td 58.333333 Tz (about ) Tj 1.852941 0 Td 65.196078 Tz (20 ) Tj 0.926471 0 Td 78.921569 Tz (nm ) Tj 1.091176 0 Td 49.754902 Tz (in ) Tj 0.761765 0 Td 45.294118 Tz (size; ) Tj 48.571429 0 0 48.571429 0 1168 Tm 26.785294 0 Td 48.039216 Tz (in ) Tj 0.782353 0 Td 50 Tz (certain ) Tj 2.285294 0 Td 60.620915 Tz (embodiments, ) Tj 4.591176 0 Td 60.906863 Tz (from ) Tj 1.667647 0 Td 57.647059 Tz (about ) Tj 1.894118 0 Td 65.196078 Tz (2 ) Tj 0.658824 0 Td 77.205882 Tz (nm ) Tj 1.152941 0 Td 48.039216 Tz (to ) Tj 0.782353 0 Td 57.647059 Tz (about ) Tj 1.997059 0 Td 60.04902 Tz (10 ) Tj 0.905882 0 Td 78.921569 Tz (nm ) Tj 1.194118 0 Td 49.754902 Tz (in ) Tj 51.428571 0 0 51.428571 0 1124 Tm 25.316667 0 Td 42.777778 Tz (size; ) Tj 1.594444 0 Td 41.049383 Tz (or, ) Tj 0.991667 0 Td 46.990741 Tz (in ) Tj 0.855556 0 Td 46.759259 Tz (certain ) Tj 2.216667 0 Td 56.983025 Tz (embodiments, ) Tj 4.355556 0 Td 54.444444 Tz (about ) Tj 1.905556 0 Td 48.611111 Tz (5.5 ) Tj 1.166667 0 Td 74.537037 Tz (nm ) Tj 1.186111 0 Td 45.37037 Tz (in ) Tj 0.816667 0 Td 46.990741 Tz (size ) Tj 1.380556 0 Td 55.092593 Tz (\(on ) Tj 51.428571 0 0 51.428571 0 1086.173967 Tm 25.297222 0 Td 48.251029 Tz (average\). ) Tj 2.877778 0 Td 63.734568 Tz (The ) Tj 1.380556 0 Td 46.990741 Tz (size ) Tj 1.361111 0 Td 59.953704 Tz (of ) Tj 0.836111 0 Td 49.691358 Tz (the ) Tj 1.166667 0 Td 47.800926 Tz (metallic ) Tj 2.586111 0 Td 49.421296 Tz (nanoparticle ) Tj 3.811111 0 Td 57.79321 Tz (formed ) Tj 2.333333 0 Td 46.180556 Tz (will ) Tj 51.428571 0 0 51.428571 0 1042.792173 Tm 25.297222 0 Td 58.333333 Tz (depend ) Tj 2.352778 0 Td 46.990741 Tz (at ) Tj 0.836111 0 Td 44.722222 Tz (least ) Tj 1.613889 0 Td 45.37037 Tz (in ) Tj 0.836111 0 Td 46.990741 Tz (part ) Tj 1.4 0 Td 58.333333 Tz (on ) Tj 1.011111 0 Td 46.759259 Tz (factors ) Tj 2.255556 0 Td 54.282407 Tz (such ) Tj 1.594444 0 Td 50.231481 Tz (as ) Tj 0.875 0 Td 50.771605 Tz (the ) Tj 1.186111 0 Td 60.493827 Tz (amount ) Tj 2.45 0 Td 59.41358 Tz (and ) Tj 51.428571 0 0 51.428571 0 1002.164948 Tm 25.297222 0 Td 50.605413 Tz (concentration ) Tj 4.219444 0 Td 56.712963 Tz (of ) Tj 0.836111 0 Td 49.691358 Tz (the ) Tj 1.147222 0 Td 53.148148 Tz (metal ) Tj 1.847222 0 Td 42.939815 Tz (salt ) Tj 1.263889 0 Td 43.75 Tz (in ) Tj 0.797222 0 Td 49.691358 Tz (the ) Tj 1.108333 0 Td 56.944444 Tz (aqueous ) Tj 2.625 0 Td 56.388889 Tz (phase ) Tj 1.944444 0 Td 43.75 Tz (in ) Tj 0.777778 0 Td 50.771605 Tz (the ) Tj 51.428571 0 0 51.428571 0 958.737235 Tm 25.297222 0 Td 45.37037 Tz (interior ) Tj 2.313889 0 Td 59.953704 Tz (of ) Tj 0.797222 0 Td 49.691358 Tz (the ) Tj 1.088889 0 Td 47.222222 Tz (vesicle ) Tj 2.158333 0 Td 47.962963 Tz (prior ) Tj 1.613889 0 Td 43.75 Tz (to ) Tj 0.758333 0 Td 50.05144 Tz (reduction ) Tj 2.897222 0 Td 58.333333 Tz (of ) Tj 0.777778 0 Td 49.691358 Tz (the ) Tj 1.108333 0 Td 52.5 Tz (metal ) Tj 1.769444 0 Td 45.37037 Tz (ion; ) Tj 1.283333 0 Td 50.771605 Tz (the ) Tj 51.428571 0 0 51.428571 0 918.398802 Tm 25.316667 0 Td 46.990741 Tz (size ) Tj 1.225 0 Td 55.092593 Tz (of ) Tj 0.738889 0 Td 48.611111 Tz (the ) Tj 0.991667 0 Td 45.37037 Tz (vesicle; ) Tj 2.333333 0 Td 48.611111 Tz (the ) Tj 0.991667 0 Td 48.206019 Tz (reaction ) Tj 2.45 0 Td 54.282407 Tz (time ) Tj 1.419444 0 Td 46.450617 Tz (for ) Tj 0.913889 0 Td 50.771605 Tz (the ) Tj 1.05 0 Td 54.444444 Tz (redox ) Tj 1.75 0 Td 52.572016 Tz (chemistry ) Tj 2.994444 0 Td 56.712963 Tz (of ) Tj 51.428571 0 0 51.428571 0 877.029412 Tm 25.277778 0 Td 50.771605 Tz (the ) Tj 1.088889 0 Td 51.851852 Tz (metal ) Tj 1.691667 0 Td 46.990741 Tz (to ) Tj 0.738889 0 Td 48.611111 Tz (occur, ) Tj 1.866667 0 Td 59.41358 Tz (and ) Tj 1.205556 0 Td 50.771605 Tz (the ) Tj 1.05 0 Td 40.833333 Tz (like. ) Tj 1.419444 0 Td 45.37037 Tz (In ) Tj 0.7 0 Td 48.206019 Tz (general, ) Tj 2.469444 0 Td 47.530864 Tz (larger ) Tj 1.827778 0 Td 47.395833 Tz (vesicles ) Tj 2.411111 0 Td 57.253086 Tz (can ) Tj 51.428571 0 0 51.428571 0 837.409207 Tm 25.297222 0 Td 61.279461 Tz (accommodate ) Tj 4.413889 0 Td 47.530864 Tz (larger ) Tj 2.080556 0 Td 52.5 Tz (metal ) Tj 2.002778 0 Td 47.916667 Tz (nanoparticles; ) Tj 4.433333 0 Td 48.611111 Tz (for ) Tj 1.186111 0 Td 55.092593 Tz (example, ) Tj 3.033333 0 Td 55.092593 Tz (a ) Tj 51.428571 0 0 51.428571 0 793.991968 Tm 25.297222 0 Td 48.611111 Tz (metallic ) Tj 2.644444 0 Td 50.231481 Tz (nanoparticle ) Tj 3.888889 0 Td 61.574074 Tz (50 ) Tj 1.011111 0 Td 74.537037 Tz (nm ) Tj 1.225 0 Td 43.75 Tz (in ) Tj 0.836111 0 Td 46.990741 Tz (size ) Tj 1.4 0 Td 54.444444 Tz (could ) Tj 1.905556 0 Td 58.333333 Tz (be ) Tj 0.991667 0 Td 58.333333 Tz (formed ) Tj 2.411111 0 Td 43.75 Tz (in ) Tj 0.816667 0 Td 55.092593 Tz (a ) Tj 40 0 0 40 0 758 Tm 32.525 0 Td 61.904762 Tz (vesicle ) Tj 2.925 0 Td 70.833333 Tz (10 ) Tj 1.1 0 Td 70.238095 Tz (microns ) Tj 3.2 0 Td 60.416667 Tz (in ) Tj 1 0 Td 54.166667 Tz (size. ) Tj 51.428571 0 0 51.428571 0 713 Tm 26.036111 0 Td 58.693416 Tz (Liposomes ) Tj 3.286111 0 Td 57.523148 Tz (have ) Tj 1.516667 0 Td 59.41358 Tz (two ) Tj 1.205556 0 Td 44.965278 Tz (distinct ) Tj 2.275 0 Td 48.206019 Tz (regions: ) Tj 2.45 0 Td 50.771605 Tz (the ) Tj 1.030556 0 Td 56.944444 Tz (aqueous ) Tj 2.527778 0 Td 52.662037 Tz (core ) Tj 1.361111 0 Td 60.493827 Tz (and ) Tj 51.428571 0 0 51.428571 0 672.812808 Tm 25.277778 0 Td 50.771605 Tz (the ) Tj 1.186111 0 Td 55.681818 Tz (hydrophobic ) Tj 3.986111 0 Td 49.074074 Tz (bilayer ) Tj 2.333333 0 Td 41.769547 Tz (interior. ) Tj 2.547222 0 Td 63.734568 Tz (The ) Tj 1.419444 0 Td 55.681818 Tz (hydrophobic ) Tj 3.986111 0 Td 49.074074 Tz (bilayer ) Tj 51.428571 0 0 51.428571 0 629.066667 Tm 25.297222 0 Td 45.37037 Tz (interior ) Tj 2.411111 0 Td 56.712963 Tz (of ) Tj 0.836111 0 Td 55.092593 Tz (a ) Tj 0.563889 0 Td 55.902778 Tz (liposome ) Tj 2.916667 0 Td 55.092593 Tz (can ) Tj 1.263889 0 Td 56.712963 Tz (be ) Tj 0.952778 0 Td 55.092593 Tz (used ) Tj 1.575 0 Td 47.530864 Tz (for ) Tj 1.069444 0 Td 52.175926 Tz (templating ) Tj 3.363889 0 Td 58.333333 Tz (of ) Tj 0.894444 0 Td 67.24537 Tz (nano ) Tj 58.571429 0 0 58.571429 0 585.418114 Tm 22.212195 0 Td 45.172764 Tz (capsules ) Tj 2.42439 0 Td 52.168022 Tz (and ) Tj 1.195122 0 Td 41.869919 Tz (related ) Tj 1.997561 0 Td 41.150719 Tz (structures.'" ) Tj 3.517073 0 Td 41.260163 Tz (Ultra-fast ) Tj 2.731707 0 Td 51.930894 Tz (mass ) Tj 1.536585 0 Td 40.904472 Tz (transfer ) Tj 51.428571 0 0 51.428571 0 543.560048 Tm 25.297222 0 Td 50.231481 Tz (across ) Tj 1.963889 0 Td 52.546296 Tz (nanometer-thin ) Tj 4.55 0 Td 50.555556 Tz (walls ) Tj 1.672222 0 Td 52.932099 Tz (has ) Tj 1.108333 0 Td 56.712963 Tz (been ) Tj 1.516667 0 Td 55.092593 Tz (used ) Tj 1.458333 0 Td 48.611111 Tz (for ) Tj 0.991667 0 Td 48.316498 Tz (controlling ) Tj 3.305556 0 Td 50.771605 Tz (the ) Tj 51.428571 0 0 51.428571 0 503.827423 Tm 25.316667 0 Td 46.990741 Tz (size ) Tj 1.225 0 Td 60.493827 Tz (and ) Tj 1.244444 0 Td 53.877315 Tz (chemical ) Tj 2.722222 0 Td 55.681818 Tz (environment ) Tj 3.830556 0 Td 55.092593 Tz (of ) Tj 0.738889 0 Td 55.452675 Tz (nanopores ) Tj 3.130556 0 Td 52.211934 Tz (imprinted ) Tj 2.975 0 Td 46.990741 Tz (in ) Tj 0.661111 0 Td 51.851852 Tz (the ) Tj 58.571429 0 0 58.571429 0 464.716364 Tm 22.195122 0 Td 44.021999 Tz (bilayer-templated ) Tj 4.660976 0 Td 43.315266 Tz (capsules. ) Tj 2.74878 0 Td 64.02439 Tz (An ) Tj 0.887805 0 Td 50.406504 Tz (aqueous ) Tj 2.270732 0 Td 46.239837 Tz (core ) Tj 1.246341 0 Td 47.425474 Tz (has ) Tj 0.990244 0 Td 51.219512 Tz (been ) Tj 1.382927 0 Td 49.085366 Tz (used ) Tj 57.142857 0 0 57.142857 0 423.380952 Tm 22.7675 0 Td 44.722222 Tz (for ) Tj 0.9275 0 Td 46.375 Tz (templating ) Tj 2.9575 0 Td 51.041667 Tz (of ) Tj 0.7 0 Td 52.5 Tz (a ) Tj 0.455 0 Td 49.583333 Tz (broad ) Tj 1.6625 0 Td 49 Tz (range ) Tj 1.6275 0 Td 52.5 Tz (of ) Tj 0.7175 0 Td 43.541667 Tz (nanoparticles. ) Tj 51.428571 0 0 51.428571 0 377.780025 Tm 26.016667 0 Td 63.734568 Tz (The ) Tj 1.263889 0 Td 50.462963 Tz (present ) Tj 2.275 0 Td 49.691358 Tz (invention ) Tj 2.819444 0 Td 43.344907 Tz (relates, ) Tj 2.216667 0 Td 45.37037 Tz (at ) Tj 0.7 0 Td 44.074074 Tz (least ) Tj 1.438889 0 Td 46.990741 Tz (in ) Tj 0.7 0 Td 43.425926 Tz (part, ) Tj 1.438889 0 Td 48.611111 Tz (to ) Tj 0.719444 0 Td 50.771605 Tz (the ) Tj 1.05 0 Td 58.873457 Tz (discov ) Tj 51.428571 0 0 51.428571 0 340.04 Tm 25.297222 0 Td 50.771605 Tz (ery ) Tj 1.147222 0 Td 46.180556 Tz (that ) Tj 1.302778 0 Td 49.691358 Tz (the ) Tj 1.108333 0 Td 49.331276 Tz (synthesis ) Tj 2.897222 0 Td 56.712963 Tz (of ) Tj 0.816667 0 Td 45.37037 Tz (silver ) Tj 1.847222 0 Td 49.358974 Tz (nanoparticles ) Tj 4.083333 0 Td 45.37037 Tz (in ) Tj 0.777778 0 Td 49.691358 Tz (the ) Tj 1.108333 0 Td 56.481481 Tz (aqueous ) Tj 51.428571 0 0 51.428571 0 295.969072 Tm 25.297222 0 Td 52.662037 Tz (core ) Tj 1.516667 0 Td 61.574074 Tz (of ) Tj 0.933333 0 Td 54.372428 Tz (liposomes ) Tj 3.208333 0 Td 57.253086 Tz (can ) Tj 1.322222 0 Td 59.953704 Tz (be ) Tj 0.991667 0 Td 60.358796 Tz (combined ) Tj 3.169444 0 Td 52.662037 Tz (with ) Tj 1.594444 0 Td 48.611111 Tz (the ) Tj 1.166667 0 Td 49.331276 Tz (synthesis ) Tj 2.955556 0 Td 58.333333 Tz (of ) Tj 51.428571 0 0 51.428571 0 257.669856 Tm 25.297222 0 Td 57.87037 Tz (polymer ) Tj 2.625 0 Td 53.472222 Tz (nanocapsules ) Tj 4.063889 0 Td 50.771605 Tz (within ) Tj 2.061111 0 Td 48.611111 Tz (the ) Tj 1.030556 0 Td 45.37037 Tz (bilayer. ) Tj 2.411111 0 Td 48.316498 Tz (Previously, ) Tj 3.363889 0 Td 63.518519 Tz (photo ) Tj 48.571429 0 0 48.571429 0 212 Tm 26.785294 0 Td 57.904412 Tz (chemical ) Tj 3.108824 0 Td 52.995643 Tz (reduction ) Tj 3.191176 0 Td 60.04902 Tz (of ) Tj 0.947059 0 Td 44.117647 Tz (silver, ) Tj 2.141176 0 Td 53.186275 Tz (as ) Tj 0.967647 0 Td 54.044118 Tz (well ) Tj 1.585294 0 Td 54.901961 Tz (as ) Tj 0.988235 0 Td 53.529412 Tz (other ) Tj 1.914706 0 Td 50.980392 Tz (metals, ) Tj 2.470588 0 Td 65.196078 Tz (was ) Tj 58.571429 0 0 58.571429 0 170.802685 Tm 22.195122 0 Td 42.366757 Tz (reported. ) Tj 2.868293 0 Td 68.292683 Tz (We ) Tj 1.109756 0 Td 49.796748 Tz (have ) Tj 1.485366 0 Td 59.756098 Tz (now ) Tj 1.382927 0 Td 49.512195 Tz (found ) Tj 1.77561 0 Td 39.837398 Tz (that ) Tj 1.229268 0 Td 51.219512 Tz (a ) Tj 0.614634 0 Td 40.54878 Tz (free-radical ) Tj 3.209756 0 Td 55.772358 Tz (photo ) Tj ET Q endstream endobj 156 0 obj << /Length 1 >> stream q endstream endobj 157 0 obj << /Length 50437 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 62.857143 0 0 62.857143 0 3023 Tm 17.325 0 Td 83.522727 Tz (US ) Tj 1.209091 0 Td 57.744108 Tz (9.248,441 ) Tj 3.420455 0 Td 74.242424 Tz (B2 ) Tj 51.428571 0 0 51.428571 0 2968 Tm 14.875 0 Td 74.537037 Tz (5 ) Tj 51.428571 0 0 51.428571 0 2915.953995 Tm 6.358333 0 Td 54.6875 Tz (chemical ) Tj 2.8 0 Td 40.833333 Tz (initiator, ) Tj 2.625 0 Td 58.981481 Tz (which ) Tj 1.983333 0 Td 37.268519 Tz (is ) Tj 0.641667 0 Td 55.902778 Tz (used ) Tj 1.497222 0 Td 48.611111 Tz (to ) Tj 0.738889 0 Td 57.87037 Tz (promote ) Tj 2.605556 0 Td 50.771605 Tz (the ) Tj 1.069444 0 Td 58.333333 Tz (polymeriza ) Tj 51.428571 0 0 51.428571 0 2876.033058 Tm 6.338889 0 Td 48.611111 Tz (tion ) Tj 1.244444 0 Td 50.771605 Tz (the ) Tj 1.011111 0 Td 45.37037 Tz (bilayer, ) Tj 2.313889 0 Td 47.800926 Tz (also ) Tj 1.302778 0 Td 42.424242 Tz (facilitates ) Tj 2.916667 0 Td 49.691358 Tz (the ) Tj 1.011111 0 Td 56.17284 Tz (growth ) Tj 2.158333 0 Td 55.092593 Tz (of ) Tj 0.738889 0 Td 48.842593 Tz (nano-particles ) Tj 4.238889 0 Td 48.611111 Tz (in ) Tj 51.428571 0 0 51.428571 0 2834.033058 Tm 6.338889 0 Td 50.771605 Tz (the ) Tj 1.088889 0 Td 56.481481 Tz (aqueous ) Tj 2.566667 0 Td 47.314815 Tz (core. ) Tj 51.428571 0 0 51.428571 0 2792.090546 Tm 7.097222 0 Td 62.654321 Tz (The ) Tj 1.4 0 Td 58.333333 Tz (polymer ) Tj 2.722222 0 Td 53.472222 Tz (nanocapsules ) Tj 4.141667 0 Td 58.333333 Tz (of ) Tj 0.855556 0 Td 51.851852 Tz (the ) Tj 1.205556 0 Td 49.331276 Tz (invention ) Tj 2.975 0 Td 55.092593 Tz (can ) Tj 1.263889 0 Td 59.953704 Tz (be ) Tj 0.991667 0 Td 64.814815 Tz (pre ) Tj 51.428571 0 0 51.428571 0 2749.544578 Tm 6.358333 0 Td 53.796296 Tz (pared ) Tj 1.75 0 Td 52.5 Tz (using ) Tj 1.711111 0 Td 51.851852 Tz (a ) Tj 0.505556 0 Td 46.296296 Tz (variety ) Tj 2.1 0 Td 55.092593 Tz (of ) Tj 0.719444 0 Td 49.826389 Tz (material ) Tj 2.508333 0 Td 58.333333 Tz (and ) Tj 1.244444 0 Td 54.282407 Tz (methods, ) Tj 2.741667 0 Td 64.814815 Tz (Some ) Tj 1.691667 0 Td 51.851852 Tz (of ) Tj 0.7 0 Td 60.277778 Tz (which ) Tj 51.428571 0 0 51.428571 0 2709.501901 Tm 6.358333 0 Td 49.691358 Tz (are ) Tj 1.127778 0 Td 64.814815 Tz (known ) Tj 2.197222 0 Td 45.37037 Tz (in ) Tj 0.777778 0 Td 50.771605 Tz (the ) Tj 1.108333 0 Td 39.699074 Tz (art. ) Tj 1.225 0 Td 46.990741 Tz (In ) Tj 0.797222 0 Td 48.611111 Tz (general, ) Tj 2.586111 0 Td 58.333333 Tz (polymer ) Tj 2.663889 0 Td 53.472222 Tz (nanocapsules ) Tj 4.102778 0 Td 49.691358 Tz (are ) Tj 51.428571 0 0 51.428571 0 2666.473068 Tm 6.358333 0 Td 58.333333 Tz (formed ) Tj 2.216667 0 Td 58.333333 Tz (by ) Tj 0.816667 0 Td 52.777778 Tz (polymerization ) Tj 4.530556 0 Td 53.472222 Tz (of ) Tj 0.719444 0 Td 57.253086 Tz (one ) Tj 1.186111 0 Td 50.231481 Tz (or ) Tj 0.7 0 Td 62.384259 Tz (more ) Tj 1.613889 0 Td 59.773663 Tz (monomers, ) Tj 3.344444 0 Td 56.481481 Tz (wherein ) Tj 51.428571 0 0 51.428571 0 2623.694344 Tm 6.338889 0 Td 50.771605 Tz (the ) Tj 1.05 0 Td 58.333333 Tz (one ) Tj 1.186111 0 Td 53.472222 Tz (or ) Tj 0.758333 0 Td 62.384259 Tz (more ) Tj 1.652778 0 Td 63.599537 Tz (monomers ) Tj 3.169444 0 Td 49.691358 Tz (are ) Tj 1.030556 0 Td 47.43266 Tz (distributed ) Tj 3.266667 0 Td 43.75 Tz (in ) Tj 0.661111 0 Td 55.092593 Tz (a ) Tj 0.466667 0 Td 44.722222 Tz (lipid ) Tj 1.458333 0 Td 49.537037 Tz (bilayer ) Tj 2.177778 0 Td 58.333333 Tz (of ) Tj 51.428571 0 0 51.428571 0 2583.880803 Tm 6.358333 0 Td 55.092593 Tz (a ) Tj 0.486111 0 Td 46.450617 Tz (scaffold, ) Tj 2.702778 0 Td 54.282407 Tz (such ) Tj 1.477778 0 Td 50.231481 Tz (as ) Tj 0.758333 0 Td 58.333333 Tz (a ) Tj 0.544444 0 Td 47.222222 Tz (vesicle ) Tj 2.158333 0 Td 39.969136 Tz (\(e.g., ) Tj 1.633333 0 Td 55.092593 Tz (a ) Tj 0.525 0 Td 44.074074 Tz (lipid ) Tj 1.497222 0 Td 44.965278 Tz (vesicle, ) Tj 2.313889 0 Td 58.333333 Tz (a ) Tj 0.525 0 Td 52.211934 Tz (liposome, ) Tj 51.428571 0 0 51.428571 0 2543.52987 Tm 6.358333 0 Td 39.969136 Tz (etc.\). ) Tj 1.730556 0 Td 72.916667 Tz (An ) Tj 1.186111 0 Td 56.481481 Tz (aqueous ) Tj 2.683333 0 Td 55.740741 Tz (phase ) Tj 1.963889 0 Td 51.527778 Tz (containing ) Tj 3.402778 0 Td 46.990741 Tz (vesicles ) Tj 2.566667 0 Td 55.092593 Tz (such ) Tj 1.633333 0 Td 50.231481 Tz (as ) Tj 0.952778 0 Td 55.902778 Tz (lipo ) Tj 51.428571 0 0 51.428571 0 2501.615385 Tm 6.377778 0 Td 59.62963 Tz (Somes ) Tj 1.983333 0 Td 40.509259 Tz (is ) Tj 0.680556 0 Td 50.05144 Tz (prepared, ) Tj 2.916667 0 Td 40.833333 Tz (e.g., ) Tj 1.4 0 Td 61.574074 Tz (by ) Tj 0.952778 0 Td 51.49177 Tz (hydrating ) Tj 2.975 0 Td 44.290123 Tz (lipids ) Tj 1.827778 0 Td 50.231481 Tz (or ) Tj 0.777778 0 Td 50.555556 Tz (other ) Tj 1.691667 0 Td 53.240741 Tz (vesicle ) Tj 51.428571 0 0 51.428571 0 2461.003901 Tm 6.358333 0 Td 56.018519 Tz (forming ) Tj 2.761111 0 Td 48.251029 Tz (reagents; ) Tj 3.072222 0 Td 63.194444 Tz (monomers ) Tj 3.461111 0 Td 47.530864 Tz (for ) Tj 1.244444 0 Td 52.314815 Tz (polymerization ) Tj 4.822222 0 Td 55.092593 Tz (can ) Tj 1.4 0 Td 59.953704 Tz (be ) Tj 51.428571 0 0 51.428571 0 2416.002442 Tm 6.358333 0 Td 58.333333 Tz (added ) Tj 1.886111 0 Td 45.37037 Tz (to ) Tj 0.7 0 Td 50.771605 Tz (the ) Tj 1.05 0 Td 44.830247 Tz (lipids ) Tj 1.769444 0 Td 51.851852 Tz (or ) Tj 0.758333 0 Td 55.092593 Tz (a ) Tj 0.486111 0 Td 49.421296 Tz (separate ) Tj 2.508333 0 Td 48.611111 Tz (Solution ) Tj 2.508333 0 Td 56.712963 Tz (of ) Tj 0.758333 0 Td 63.194444 Tz (monomers ) Tj 3.188889 0 Td 56.17284 Tz (can ) Tj 1.147222 0 Td 59.953704 Tz (be ) Tj 51.428571 0 0 51.428571 0 2377.766585 Tm 6.358333 0 Td 58.333333 Tz (added ) Tj 1.944444 0 Td 45.37037 Tz (to ) Tj 0.758333 0 Td 51.851852 Tz (a ) Tj 0.525 0 Td 54.768519 Tz (pre-formed ) Tj 3.480556 0 Td 55.497685 Tz (liposome ) Tj 2.858333 0 Td 48.341049 Tz (preparation. ) Tj 3.694444 0 Td 56.388889 Tz (Metal ) Tj 1.905556 0 Td 50.231481 Tz (ions ) Tj 1.419444 0 Td 49.691358 Tz (are ) Tj 51.428571 0 0 51.428571 0 2335.844501 Tm 6.358333 0 Td 50.771605 Tz (dissolved ) Tj 2.975 0 Td 45.37037 Tz (in ) Tj 0.777778 0 Td 49.691358 Tz (the ) Tj 1.108333 0 Td 56.018519 Tz (aqueous ) Tj 2.605556 0 Td 55.092593 Tz (phase ) Tj 1.866667 0 Td 40.509259 Tz (\(e.g., ) Tj 1.672222 0 Td 61.574074 Tz (by ) Tj 0.972222 0 Td 57.613169 Tz (combining ) Tj 3.325 0 Td 51.851852 Tz (a ) Tj 0.583333 0 Td 52.5 Tz (metal ) Tj 51.428571 0 0 51.428571 0 2291.525672 Tm 6.377778 0 Td 42.12963 Tz (salt ) Tj 1.127778 0 Td 51.851852 Tz (or ) Tj 0.738889 0 Td 42.777778 Tz (salts ) Tj 1.419444 0 Td 53.472222 Tz (with ) Tj 1.4 0 Td 50.771605 Tz (the ) Tj 1.05 0 Td 44.290123 Tz (lipids ) Tj 1.730556 0 Td 47.962963 Tz (prior ) Tj 1.536111 0 Td 46.990741 Tz (to ) Tj 0.719444 0 Td 52.572016 Tz (formation ) Tj 2.994444 0 Td 53.472222 Tz (of ) Tj 0.719444 0 Td 47.800926 Tz (vesicles ) Tj 2.45 0 Td 43.75 Tz (in ) Tj 0.680556 0 Td 49.691358 Tz (the ) Tj 51.428571 0 0 51.428571 0 2251.651282 Tm 6.358333 0 Td 56.481481 Tz (aqueous ) Tj 2.586111 0 Td 51.311728 Tz (phase, ) Tj 2.061111 0 Td 53.472222 Tz (or ) Tj 0.797222 0 Td 59.953704 Tz (by ) Tj 0.972222 0 Td 55.092593 Tz (adding ) Tj 2.177778 0 Td 50.771605 Tz (the ) Tj 1.147222 0 Td 52.5 Tz (metal ) Tj 1.788889 0 Td 39.537037 Tz (salt, ) Tj 1.438889 0 Td 50.231481 Tz (or ) Tj 0.797222 0 Td 55.092593 Tz (a ) Tj 0.544444 0 Td 48.206019 Tz (solution ) Tj 2.566667 0 Td 56.712963 Tz (of ) Tj 51.428571 0 0 51.428571 0 2211.314217 Tm 6.358333 0 Td 53.796296 Tz (metal ) Tj 1.788889 0 Td 39.537037 Tz (salt, ) Tj 1.322222 0 Td 48.611111 Tz (to ) Tj 0.738889 0 Td 50.771605 Tz (the ) Tj 1.05 0 Td 55.092593 Tz (pre-formed ) Tj 3.461111 0 Td 55.902778 Tz (liposome ) Tj 2.819444 0 Td 48.341049 Tz (preparation. ) Tj 3.636111 0 Td 64.814815 Tz (The ) Tj 1.302778 0 Td 74.537037 Tz (pho ) Tj 51.428571 0 0 51.428571 0 2167.705882 Tm 6.338889 0 Td 44.191919 Tz (toinitiator ) Tj 3.111111 0 Td 55.092593 Tz (can ) Tj 1.225 0 Td 58.333333 Tz (be ) Tj 0.894444 0 Td 58.333333 Tz (added ) Tj 1.983333 0 Td 48.611111 Tz (separately ) Tj 3.15 0 Td 53.472222 Tz (or ) Tj 0.797222 0 Td 51.041667 Tz (together ) Tj 2.625 0 Td 53.472222 Tz (with ) Tj 1.516667 0 Td 52.777778 Tz (another ) Tj 51.428571 0 0 51.428571 0 2126.338583 Tm 6.358333 0 Td 60.133745 Tz (component ) Tj 3.538889 0 Td 39.969136 Tz (\(e.g., ) Tj 1.75 0 Td 41.589506 Tz (lipid, ) Tj 1.827778 0 Td 52.5 Tz (metal ) Tj 1.886111 0 Td 38.888889 Tz (salt, ) Tj 1.438889 0 Td 59.41358 Tz (and ) Tj 1.322222 0 Td 51.851852 Tz (the ) Tj 1.225 0 Td 40.509259 Tz (like\). ) Tj 1.769444 0 Td 64.00463 Tz (Once ) Tj 1.827778 0 Td 49.691358 Tz (the ) Tj 51.428571 0 0 51.428571 0 2088.054334 Tm 6.358333 0 Td 49.331276 Tz (vesicle-containing ) Tj 5.813889 0 Td 49.789562 Tz (preparation ) Tj 3.791667 0 Td 42.12963 Tz (is ) Tj 0.991667 0 Td 53.703704 Tz (formed, ) Tj 2.741667 0 Td 51.131687 Tz (including ) Tj 3.247222 0 Td 49.691358 Tz (the ) Tj 51.428571 0 0 51.428571 0 2042.188387 Tm 6.358333 0 Td 56.565657 Tz (monomer\(s\), ) Tj 4.063889 0 Td 50.771605 Tz (the ) Tj 1.283333 0 Td 51.851852 Tz (metal ) Tj 1.905556 0 Td 39.537037 Tz (salt, ) Tj 1.516667 0 Td 58.333333 Tz (and ) Tj 1.380556 0 Td 50.771605 Tz (the ) Tj 1.244444 0 Td 45.802469 Tz (photoinitiator, ) Tj 4.472222 0 Td 53.148148 Tz (metal ) Tj 51.428571 0 0 51.428571 0 2005.820839 Tm 6.358333 0 Td 49.608262 Tz (nanoparticles ) Tj 4.238889 0 Td 53.292181 Tz (entrapped ) Tj 3.227778 0 Td 45.37037 Tz (in ) Tj 0.933333 0 Td 58.333333 Tz (polymer ) Tj 2.8 0 Td 53.472222 Tz (nanocapsules ) Tj 4.219444 0 Td 55.092593 Tz (can ) Tj 1.341667 0 Td 59.953704 Tz (be ) Tj 51.428571 0 0 51.428571 0 1959.790932 Tm 6.358333 0 Td 58.333333 Tz (formed ) Tj 2.313889 0 Td 59.953704 Tz (by ) Tj 0.952778 0 Td 45.664983 Tz (irradiation ) Tj 3.266667 0 Td 52.662037 Tz (with ) Tj 1.497222 0 Td 44.722222 Tz (light ) Tj 1.555556 0 Td 45.37037 Tz (at ) Tj 0.738889 0 Td 51.851852 Tz (a ) Tj 0.544444 0 Td 55.416667 Tz (wavelength ) Tj 3.558333 0 Td 46.990741 Tz (suitable ) Tj 2.469444 0 Td 46.990741 Tz (to ) Tj 51.428571 0 0 51.428571 0 1918.361502 Tm 6.358333 0 Td 46.990741 Tz (activate ) Tj 2.333333 0 Td 50.771605 Tz (the ) Tj 0.991667 0 Td 47.916667 Tz (photoinitiator ) Tj 4.141667 0 Td 39.969136 Tz (\(e.g., ) Tj 1.575 0 Td 45.075758 Tz (ultraviolet ) Tj 3.091667 0 Td 64.00463 Tz (\(UV\) ) Tj 1.652778 0 Td 41.589506 Tz (light, ) Tj 1.613889 0 Td 55.092593 Tz (such ) Tj 1.458333 0 Td 50.231481 Tz (as ) Tj 51.428571 0 0 51.428571 0 1878.048662 Tm 6.358333 0 Td 44.722222 Tz (light ) Tj 1.477778 0 Td 46.990741 Tz (at ) Tj 0.719444 0 Td 54.444444 Tz (about ) Tj 1.788889 0 Td 60.493827 Tz (254 ) Tj 1.283333 0 Td 53.472222 Tz (nm\). ) Tj 1.458333 0 Td 63.734568 Tz (The ) Tj 1.322222 0 Td 53.148148 Tz (metal ) Tj 1.788889 0 Td 49.358974 Tz (nanoparticles ) Tj 4.005556 0 Td 53.652263 Tz (entrapped ) Tj 3.072222 0 Td 48.611111 Tz (in ) Tj 51.428571 0 0 51.428571 0 1836.450063 Tm 6.358333 0 Td 58.333333 Tz (polymer ) Tj 2.741667 0 Td 53.20216 Tz (nanocapsules ) Tj 4.122222 0 Td 55.092593 Tz (can ) Tj 1.244444 0 Td 52.662037 Tz (then ) Tj 1.536111 0 Td 58.333333 Tz (be ) Tj 0.972222 0 Td 47.395833 Tz (isolated ) Tj 2.547222 0 Td 58.333333 Tz (and ) Tj 1.322222 0 Td 47.395833 Tz (purified ) Tj 2.527778 0 Td 45.37037 Tz (if ) Tj 48.571429 0 0 48.571429 0 1793 Tm 6.732353 0 Td 50.183824 Tz (desired, ) Tj 2.614706 0 Td 51.470588 Tz (as ) Tj 0.844118 0 Td 54.520697 Tz (described ) Tj 3.129412 0 Td 50 Tz (herein. ) Tj 51.428571 0 0 51.428571 0 1750.981651 Tm 7.116667 0 Td 49.421296 Tz (Suitable ) Tj 2.644444 0 Td 63.194444 Tz (monomers ) Tj 3.305556 0 Td 55.092593 Tz (can ) Tj 1.263889 0 Td 47.530864 Tz (be, ) Tj 1.127778 0 Td 48.611111 Tz (for ) Tj 1.088889 0 Td 55.092593 Tz (example, ) Tj 2.897222 0 Td 57.253086 Tz (any ) Tj 1.341667 0 Td 63.194444 Tz (monomers ) Tj 51.428571 0 0 51.428571 0 1712.110831 Tm 6.338889 0 Td 56.712963 Tz (used ) Tj 1.711111 0 Td 47.530864 Tz (for ) Tj 1.166667 0 Td 46.450617 Tz (free-radical ) Tj 3.675 0 Td 50.987654 Tz (polymerization, ) Tj 4.958333 0 Td 55.092593 Tz (Such ) Tj 1.672222 0 Td 51.851852 Tz (as ) Tj 0.952778 0 Td 61.934156 Tz (compounds ) Tj 51.428571 0 0 51.428571 0 1667.572139 Tm 6.358333 0 Td 51.203704 Tz (containing ) Tj 3.325 0 Td 59.41358 Tz (one ) Tj 1.302778 0 Td 53.472222 Tz (or ) Tj 0.913889 0 Td 60.763889 Tz (more ) Tj 1.711111 0 Td 53.347578 Tz (carbon-carbon ) Tj 4.452778 0 Td 55.092593 Tz (double ) Tj 2.236111 0 Td 52.932099 Tz (bonds; ) Tj 2.197222 0 Td 55.902778 Tz (Such ) Tj 52.857143 0 0 52.857143 0 1628.600967 Tm 6.186486 0 Td 49.099099 Tz (alkenyl ) Tj 2.232432 0 Td 59.90991 Tz (compounds ) Tj 3.424324 0 Td 54.654655 Tz (can ) Tj 1.172973 0 Td 56.756757 Tz (be ) Tj 0.813514 0 Td 51.764264 Tz (polymerized, ) Tj 3.897297 0 Td 40.36036 Tz (e.g., ) Tj 1.362162 0 Td 59.90991 Tz (by ) Tj 0.889189 0 Td 46.509009 Tz (free ) Tj 1.286486 0 Td 45.495495 Tz (radical ) Tj 51.428571 0 0 51.428571 0 1589.709637 Tm 6.358333 0 Td 52.314815 Tz (polymerization ) Tj 4.783333 0 Td 46.990741 Tz (to ) Tj 0.933333 0 Td 52.777778 Tz (prepare ) Tj 2.566667 0 Td 54.73251 Tz (polymeric ) Tj 3.363889 0 Td 49.583333 Tz (\(including ) Tj 3.383333 0 Td 57.87037 Tz (co-poly ) Tj 51.428571 0 0 51.428571 0 1545.359801 Tm 6.358333 0 Td 52.391975 Tz (meric\) ) Tj 2.333333 0 Td 51.602564 Tz (nanocapsules. ) Tj 4.491667 0 Td 57.973251 Tz (Exemplary ) Tj 3.577778 0 Td 60.853909 Tz (monomeric ) Tj 3.713889 0 Td 61.934156 Tz (compounds ) Tj 51.428571 0 0 51.428571 0 1504.049102 Tm 6.358333 0 Td 51.388889 Tz (include ) Tj 2.313889 0 Td 58.333333 Tz (a ) Tj 0.544444 0 Td 50 Tz (styrene ) Tj 2.275 0 Td 53.472222 Tz (or ) Tj 0.797222 0 Td 50.462963 Tz (styrene ) Tj 2.313889 0 Td 47.314815 Tz (derivative ) Tj 3.033333 0 Td 49.907407 Tz (\(including ) Tj 3.15 0 Td 50.555556 Tz (t-butylsty ) Tj 51.428571 0 0 51.428571 0 1461.484561 Tm 6.358333 0 Td 52.662037 Tz (rene ) Tj 1.380556 0 Td 59.41358 Tz (and ) Tj 1.186111 0 Td 51.419753 Tz (divinylbenzene\) ) Tj 4.783333 0 Td 59.41358 Tz (and ) Tj 1.186111 0 Td 47.890947 Tz (acrylates ) Tj 2.722222 0 Td 51.851852 Tz (\(such ) Tj 1.711111 0 Td 48.611111 Tz (as ) Tj 0.738889 0 Td 46.759259 Tz (acrylic ) Tj 2.1 0 Td 45.910494 Tz (esters ) Tj 51.428571 0 0 51.428571 0 1420.589436 Tm 6.358333 0 Td 58.333333 Tz (and ) Tj 1.341667 0 Td 51.262626 Tz (methacrylic ) Tj 3.616667 0 Td 46.450617 Tz (esters ) Tj 1.944444 0 Td 50.771605 Tz (including ) Tj 2.955556 0 Td 50.898693 Tz (butylmethacylate, ) Tj 5.444444 0 Td 51.388889 Tz (tert-bu ) Tj 51.428571 0 0 51.428571 0 1380.983648 Tm 6.338889 0 Td 49.21875 Tz (tylmethacrylate, ) Tj 5.133333 0 Td 51.446759 Tz (ethylene ) Tj 2.877778 0 Td 50.231481 Tz (glycol ) Tj 2.216667 0 Td 49.907407 Tz (dimethacrylate, ) Tj 4.9 0 Td 59.41358 Tz (and ) Tj 1.477778 0 Td 49.691358 Tz (the ) Tj 51.428571 0 0 51.428571 0 1336.852459 Tm 6.358333 0 Td 41.049383 Tz (like\). ) Tj 1.672222 0 Td 58.738426 Tz (Examples ) Tj 2.936111 0 Td 55.092593 Tz (of ) Tj 0.738889 0 Td 46.990741 Tz (suitable ) Tj 2.352778 0 Td 51.311728 Tz (binary ) Tj 1.983333 0 Td 57.973251 Tz (copolymer ) Tj 3.247222 0 Td 54.166667 Tz (systems ) Tj 2.411111 0 Td 50.925926 Tz (include ) Tj 51.428571 0 0 51.428571 0 1298.485649 Tm 6.338889 0 Td 47.276688 Tz (tert-butylstyrene ) Tj 4.977778 0 Td 60.493827 Tz (and ) Tj 1.283333 0 Td 50.771605 Tz (divinylbenzene, ) Tj 4.783333 0 Td 48.905724 Tz (tert-butylmethacrylate ) Tj 51.428571 0 0 51.428571 0 1255.939759 Tm 6.358333 0 Td 58.333333 Tz (and ) Tj 1.302778 0 Td 51.851852 Tz (ethylene ) Tj 2.741667 0 Td 50.231481 Tz (glycol ) Tj 2.119444 0 Td 49.475309 Tz (dimethacrylate, ) Tj 4.725 0 Td 51.470588 Tz (butylmethacrylate ) Tj 5.522222 0 Td 60.493827 Tz (and ) Tj 51.428571 0 0 51.428571 0 1213.766497 Tm 6.358333 0 Td 51.446759 Tz (ethylene ) Tj 2.780556 0 Td 49.691358 Tz (glycol ) Tj 2.119444 0 Td 50.123457 Tz (dimethacrylate, ) Tj 4.802778 0 Td 59.41358 Tz (and ) Tj 1.380556 0 Td 49.691358 Tz (the ) Tj 1.205556 0 Td 40.833333 Tz (like. ) Tj 1.536111 0 Td 54.166667 Tz (Ternary ) Tj 2.586111 0 Td 60.493827 Tz (and ) Tj 51.428571 0 0 51.428571 0 1171.878136 Tm 6.338889 0 Td 52.932099 Tz (higher ) Tj 2.061111 0 Td 56.388889 Tz (copolymers ) Tj 3.577778 0 Td 55.092593 Tz (can ) Tj 1.166667 0 Td 49.421296 Tz (also ) Tj 1.380556 0 Td 58.333333 Tz (be ) Tj 0.875 0 Td 49.691358 Tz (prepared. ) Tj 51.428571 0 0 51.428571 0 1127.067669 Tm 7.116667 0 Td 52.314815 Tz (Polymerization ) Tj 4.588889 0 Td 58.333333 Tz (of ) Tj 0.777778 0 Td 64.00463 Tz (monomers ) Tj 3.247222 0 Td 55.092593 Tz (can ) Tj 1.186111 0 Td 58.333333 Tz (be ) Tj 0.855556 0 Td 44.290123 Tz (initiated ) Tj 2.586111 0 Td 51.851852 Tz (using ) Tj 1.75 0 Td 47.530864 Tz (initia ) Tj 51.428571 0 0 51.428571 0 1085.157635 Tm 6.338889 0 Td 46.180556 Tz (tors ) Tj 1.302778 0 Td 55.092593 Tz (such ) Tj 1.497222 0 Td 51.851852 Tz (as ) Tj 0.816667 0 Td 47.800926 Tz (free ) Tj 1.322222 0 Td 47.222222 Tz (radical ) Tj 2.197222 0 Td 42.453704 Tz (initiators ) Tj 2.741667 0 Td 53.472222 Tz (or ) Tj 0.777778 0 Td 47.314815 Tz (photoinitiators ) Tj 4.452778 0 Td 51.851852 Tz (\(such ) Tj 1.769444 0 Td 50.231481 Tz (as ) Tj 51.428571 0 0 51.428571 0 1046.666267 Tm 6.358333 0 Td 53.11214 Tz (2,2-dimethoxy-2-phenylacetophenone\). ) Tj 11.9 0 Td 56.388889 Tz (Other ) Tj 2.080556 0 Td 46.180556 Tz (free ) Tj 1.555556 0 Td 45.833333 Tz (radical ) Tj 51.428571 0 0 51.428571 0 1002.293194 Tm 6.358333 0 Td 43.101852 Tz (initiators ) Tj 2.877778 0 Td 53.472222 Tz (or ) Tj 0.894444 0 Td 47.314815 Tz (photoinitiators ) Tj 4.530556 0 Td 65.462963 Tz (known ) Tj 2.294444 0 Td 43.75 Tz (in ) Tj 0.816667 0 Td 50.771605 Tz (the ) Tj 1.205556 0 Td 43.209877 Tz (art ) Tj 1.069444 0 Td 54.012346 Tz (can ) Tj 1.263889 0 Td 59.953704 Tz (be ) Tj 0.991667 0 Td 49.907407 Tz (used. ) Tj 51.428571 0 0 51.428571 0 959.767333 Tm 6.358333 0 Td 52.10114 Tz (Water-soluble ) Tj 4.2 0 Td 42.777778 Tz (initiators ) Tj 2.702778 0 Td 53.472222 Tz (or ) Tj 0.738889 0 Td 55.387205 Tz (hydrophobic ) Tj 3.830556 0 Td 42.777778 Tz (initiators ) Tj 2.702778 0 Td 55.092593 Tz (can ) Tj 1.127778 0 Td 58.333333 Tz (be ) Tj 0.836111 0 Td 56.712963 Tz (used ) Tj 51.428571 0 0 51.428571 0 919.763819 Tm 6.358333 0 Td 45.37037 Tz (in ) Tj 0.836111 0 Td 51.203704 Tz (order ) Tj 1.730556 0 Td 48.611111 Tz (to ) Tj 0.836111 0 Td 52.599715 Tz (independently ) Tj 4.394444 0 Td 51.851852 Tz (vary ) Tj 1.516667 0 Td 50.356125 Tz (concentration ) Tj 4.180556 0 Td 59.41358 Tz (and ) Tj 1.341667 0 Td 49.691358 Tz (nature ) Tj 2.041667 0 Td 56.712963 Tz (of ) Tj 51.428571 0 0 51.428571 0 878.143577 Tm 6.358333 0 Td 50.231481 Tz (ions ) Tj 1.438889 0 Td 43.75 Tz (in ) Tj 0.758333 0 Td 49.691358 Tz (the ) Tj 1.088889 0 Td 56.944444 Tz (aqueous ) Tj 2.625 0 Td 51.851852 Tz (core ) Tj 1.458333 0 Td 58.333333 Tz (and ) Tj 1.244444 0 Td 55.681818 Tz (hydrophobic ) Tj 3.927778 0 Td 63.194444 Tz (monomers ) Tj 3.286111 0 Td 43.75 Tz (in ) Tj 0.758333 0 Td 49.691358 Tz (the ) Tj 51.428571 0 0 51.428571 0 836.263835 Tm 6.338889 0 Td 44.965278 Tz (bilayer. ) Tj 2.45 0 Td 63.734568 Tz (The ) Tj 1.419444 0 Td 60.493827 Tz (amount ) Tj 2.430556 0 Td 59.953704 Tz (of ) Tj 0.894444 0 Td 47.685185 Tz (photoinitiator ) Tj 4.277778 0 Td 43.75 Tz (to ) Tj 0.816667 0 Td 55.092593 Tz (use ) Tj 1.263889 0 Td 55.092593 Tz (can ) Tj 1.263889 0 Td 59.953704 Tz (be ) Tj 0.991667 0 Td 55.740741 Tz (deter ) Tj 51.428571 0 0 51.428571 0 793.661146 Tm 6.358333 0 Td 60.925926 Tz (mined ) Tj 2.002778 0 Td 59.953704 Tz (by ) Tj 0.933333 0 Td 59.41358 Tz (one ) Tj 1.244444 0 Td 58.333333 Tz (of ) Tj 0.797222 0 Td 51.041667 Tz (ordinary ) Tj 2.683333 0 Td 40.833333 Tz (skill ) Tj 1.438889 0 Td 45.37037 Tz (in ) Tj 0.777778 0 Td 48.611111 Tz (the ) Tj 1.069444 0 Td 38.888889 Tz (art; ) Tj 1.166667 0 Td 45.37037 Tz (in ) Tj 0.758333 0 Td 46.759259 Tz (certain ) Tj 2.177778 0 Td 66.975309 Tz (embodi ) Tj 51.428571 0 0 51.428571 0 751.72549 Tm 6.358333 0 Td 52.932099 Tz (ments, ) Tj 2.1 0 Td 49.691358 Tz (the ) Tj 1.088889 0 Td 45.775463 Tz (starting ) Tj 2.391667 0 Td 54.890046 Tz (monomerinitiator ) Tj 5.444444 0 Td 43.425926 Tz (ratio ) Tj 1.497222 0 Td 54.012346 Tz (can ) Tj 1.186111 0 Td 48.611111 Tz (be, ) Tj 1.05 0 Td 40.833333 Tz (e.g., ) Tj 1.419444 0 Td 51.041667 Tz (50:1 ) Tj 51.428571 0 0 51.428571 0 711.315789 Tm 6.338889 0 Td 46.990741 Tz (to ) Tj 0.777778 0 Td 50.771605 Tz (500:1, ) Tj 2.041667 0 Td 61.574074 Tz (more ) Tj 1.652778 0 Td 49.907407 Tz (preferably ) Tj 3.169444 0 Td 54.444444 Tz (about ) Tj 1.769444 0 Td 51.311728 Tz (200:1. ) Tj 51.428571 0 0 51.428571 0 671.911582 Tm 7.116667 0 Td 50.084175 Tz (Preparation ) Tj 3.519444 0 Td 56.712963 Tz (of ) Tj 0.777778 0 Td 58.333333 Tz (polymer ) Tj 2.644444 0 Td 53.20216 Tz (nanocapsules ) Tj 4.005556 0 Td 58.333333 Tz (of ) Tj 0.777778 0 Td 50.771605 Tz (the ) Tj 1.088889 0 Td 49.691358 Tz (invention ) Tj 2.877778 0 Td 58.333333 Tz (can ) Tj 51.428571 0 0 51.428571 0 631.79243 Tm 6.338889 0 Td 59.953704 Tz (be ) Tj 0.894444 0 Td 56.17284 Tz (performed ) Tj 3.188889 0 Td 45.37037 Tz (at ) Tj 0.719444 0 Td 56.17284 Tz (any ) Tj 1.205556 0 Td 46.990741 Tz (suitable ) Tj 2.45 0 Td 50.771605 Tz (temperature, ) Tj 3.811111 0 Td 40.833333 Tz (e.g., ) Tj 1.438889 0 Td 43.75 Tz (at ) Tj 0.680556 0 Td 58.333333 Tz (a ) Tj 0.486111 0 Td 62.037037 Tz (tempera ) Tj 51.428571 0 0 51.428571 0 585.498783 Tm 6.338889 0 Td 48.611111 Tz (ture ) Tj 1.322222 0 Td 57.523148 Tz (from ) Tj 1.555556 0 Td 53.796296 Tz (about ) Tj 1.788889 0 Td 59.143519 Tz (0C. ) Tj 1.594444 0 Td 46.990741 Tz (to ) Tj 0.719444 0 Td 54.444444 Tz (about ) Tj 1.827778 0 Td 55.092593 Tz (100C., ) Tj 2.508333 0 Td 61.574074 Tz (more ) Tj 1.594444 0 Td 49.907407 Tz (preferably ) Tj 3.169444 0 Td 59.143519 Tz (from ) Tj 51.428571 0 0 51.428571 0 543.816327 Tm 6.358333 0 Td 54.444444 Tz (about ) Tj 1.827778 0 Td 56.17284 Tz (20 ) Tj 1.263889 0 Td 53.472222 Tz (C. ) Tj 0.894444 0 Td 45.37037 Tz (to ) Tj 0.758333 0 Td 55.092593 Tz (about ) Tj 1.866667 0 Td 55.092593 Tz (50 ) Tj 1.225 0 Td 55.092593 Tz (C. ) Tj 0.855556 0 Td 64.814815 Tz (The ) Tj 1.4 0 Td 52.441077 Tz (temperature ) Tj 3.694444 0 Td 48.611111 Tz (selected ) Tj 2.527778 0 Td 47.800926 Tz (will ) Tj 51.428571 0 0 51.428571 0 503.926594 Tm 6.358333 0 Td 58.333333 Tz (depend ) Tj 2.236111 0 Td 59.953704 Tz (on ) Tj 0.855556 0 Td 46.759259 Tz (factors ) Tj 2.119444 0 Td 55.092593 Tz (such ) Tj 1.458333 0 Td 50.231481 Tz (as ) Tj 0.738889 0 Td 49.691358 Tz (the ) Tj 1.069444 0 Td 58.333333 Tz (monomer\(s\) ) Tj 3.655556 0 Td 45.37037 Tz (to ) Tj 0.680556 0 Td 58.333333 Tz (be ) Tj 0.816667 0 Td 52.932099 Tz (polymerized, ) Tj 51.428571 0 0 51.428571 0 463.361011 Tm 6.338889 0 Td 50.771605 Tz (the ) Tj 1.088889 0 Td 49.537037 Tz (solvent ) Tj 2.236111 0 Td 55.632716 Tz (system ) Tj 2.216667 0 Td 48.206019 Tz (selected ) Tj 2.488889 0 Td 40.509259 Tz (\(e.g., ) Tj 1.613889 0 Td 50.771605 Tz (the ) Tj 1.05 0 Td 53.030303 Tz (temperature ) Tj 3.655556 0 Td 46.990741 Tz (will ) Tj 1.283333 0 Td 61.574074 Tz (gener ) Tj 51.428571 0 0 51.428571 0 421.901682 Tm 6.358333 0 Td 45.37037 Tz (ally ) Tj 1.341667 0 Td 58.333333 Tz (be ) Tj 0.933333 0 Td 56.944444 Tz (between ) Tj 2.702778 0 Td 48.611111 Tz (the ) Tj 1.127778 0 Td 49.826389 Tz (freezing ) Tj 2.625 0 Td 58.333333 Tz (and ) Tj 1.302778 0 Td 49.074074 Tz (boiling ) Tj 2.294444 0 Td 49.691358 Tz (points ) Tj 2.022222 0 Td 61.574074 Tz (of ) Tj 0.913889 0 Td 48.611111 Tz (the ) Tj 1.127778 0 Td 59.41358 Tz (sol ) Tj 51.428571 0 0 51.428571 0 380.1728 Tm 6.358333 0 Td 45.910494 Tz (Vent\), ) Tj 1.847222 0 Td 50.771605 Tz (the ) Tj 1.088889 0 Td 55.497685 Tz (liposome ) Tj 2.858333 0 Td 55.681818 Tz (components, ) Tj 3.830556 0 Td 60.493827 Tz (and ) Tj 1.244444 0 Td 50.771605 Tz (the ) Tj 1.088889 0 Td 41.481481 Tz (like. ) Tj 51.428571 0 0 51.428571 0 340.042607 Tm 7.116667 0 Td 46.990741 Tz (In ) Tj 0.719444 0 Td 48.611111 Tz (general, ) Tj 2.488889 0 Td 58.333333 Tz (polymer ) Tj 2.625 0 Td 53.20216 Tz (nanocapsules ) Tj 3.986111 0 Td 56.712963 Tz (of ) Tj 0.758333 0 Td 50.771605 Tz (the ) Tj 1.069444 0 Td 49.691358 Tz (invention ) Tj 2.838889 0 Td 49.691358 Tz (are ) Tj 1.05 0 Td 64.814815 Tz (pre ) Tj 51.428571 0 0 51.428571 0 299.923636 Tm 6.358333 0 Td 53.796296 Tz (pared ) Tj 1.75 0 Td 53.148148 Tz (using ) Tj 1.730556 0 Td 55.092593 Tz (a ) Tj 0.486111 0 Td 43.425926 Tz (lipid ) Tj 1.419444 0 Td 49.074074 Tz (bilayer ) Tj 2.158333 0 Td 51.851852 Tz (as ) Tj 0.758333 0 Td 58.333333 Tz (a ) Tj 0.486111 0 Td 52.932099 Tz (template ) Tj 3.305556 0 Td 47.530864 Tz (for ) Tj 0.952778 0 Td 53.009259 Tz (polymerization ) Tj 51.428571 0 0 51.428571 0 253.44898 Tm 6.358333 0 Td 56.712963 Tz (of ) Tj 0.758333 0 Td 49.691358 Tz (the ) Tj 1.069444 0 Td 54.503367 Tz (nanocapsule ) Tj 3.733333 0 Td 45.37037 Tz (shell'. ) Tj 2.411111 0 Td 45.37037 Tz (In ) Tj 0.7 0 Td 47.222222 Tz (certain ) Tj 2.158333 0 Td 56.712963 Tz (embodiments, ) Tj 4.277778 0 Td 48.611111 Tz (the ) Tj 1.030556 0 Td 45.37037 Tz (lipid ) Tj 51.428571 0 0 51.428571 0 214.070707 Tm 6.338889 0 Td 49.537037 Tz (bilayer ) Tj 2.236111 0 Td 40.509259 Tz (is ) Tj 0.680556 0 Td 55.092593 Tz (a ) Tj 0.544444 0 Td 44.074074 Tz (lipid ) Tj 1.497222 0 Td 49.074074 Tz (bilayer ) Tj 2.255556 0 Td 55.092593 Tz (of ) Tj 0.777778 0 Td 55.092593 Tz (a ) Tj 0.544444 0 Td 47.222222 Tz (vesicle ) Tj 2.177778 0 Td 45.37037 Tz (in ) Tj 0.738889 0 Td 58.333333 Tz (an ) Tj 0.913889 0 Td 56.481481 Tz (aqueous ) Tj 2.566667 0 Td 46.8107 Tz (solution; ) Tj 51.428571 0 0 51.428571 0 171.283117 Tm 6.358333 0 Td 47.395833 Tz (vesicles ) Tj 2.644444 0 Td 51.388889 Tz (include ) Tj 2.508333 0 Td 52.211934 Tz (liposome. ) Tj 3.169444 0 Td 63.734568 Tz (The ) Tj 1.516667 0 Td 53.472222 Tz (term ) Tj 1.652778 0 Td 55.416667 Tz (liposome' ) Tj 3.655556 0 Td 51.851852 Tz (as ) Tj 1.011111 0 Td 55.902778 Tz (used ) Tj 30 0 0 30 0 2547 Tm 41.666667 0 Td 75 Tz (10 ) Tj 30 0 0 30 0 2339 Tm 41.666667 0 Td 72.222222 Tz (15 ) Tj 30 0 0 30 0 1923 Tm 41.6 0 Td 77.777778 Tz (25 ) Tj 30 0 0 30 0 1716 Tm 41.6 0 Td 80.555556 Tz (30 ) Tj 30 0 0 30 0 1507 Tm 41.6 0 Td 77.777778 Tz (35 ) Tj 30 0 0 30 0 1299 Tm 41.566667 0 Td 83.333333 Tz (40 ) Tj 30 0 0 30 0 1091 Tm 41.566667 0 Td 80.555556 Tz (45 ) Tj 30 0 0 30 0 883 Tm 41.6 0 Td 80.555556 Tz (50 ) Tj 30 0 0 30 0 675 Tm 41.6 0 Td 77.777778 Tz (55 ) Tj 30 0 0 30 0 467 Tm 41.633333 0 Td 77.777778 Tz (60 ) Tj 30 0 0 30 0 259 Tm 41.633333 0 Td 75 Tz (65 ) Tj 52.857143 0 0 52.857143 0 2968 Tm 32.9 0 Td 69.369369 Tz (6 ) Tj 51.428571 0 0 51.428571 0 2915.456547 Tm 25.277778 0 Td 50.771605 Tz (herein ) Tj 1.963889 0 Td 50.231481 Tz (includes ) Tj 2.547222 0 Td 51.311728 Tz (conventional ) Tj 3.830556 0 Td 50.968013 Tz (unilamellar ) Tj 3.422222 0 Td 54.372428 Tz (liposomes ) Tj 3.091667 0 Td 52.777778 Tz (\(having ) Tj 2.313889 0 Td 55.092593 Tz (a ) Tj 51.428571 0 0 51.428571 0 2874.015686 Tm 25.297222 0 Td 44.722222 Tz (lipid ) Tj 1.633333 0 Td 48.611111 Tz (bilayer ) Tj 2.294444 0 Td 59.41358 Tz (and ) Tj 1.361111 0 Td 56.712963 Tz (an ) Tj 0.952778 0 Td 57.407407 Tz (aqueous ) Tj 2.702778 0 Td 55.740741 Tz (phase ) Tj 1.963889 0 Td 45.37037 Tz (in ) Tj 0.836111 0 Td 50.771605 Tz (the ) Tj 1.225 0 Td 41.805556 Tz (interior\). ) Tj 2.838889 0 Td 56.388889 Tz (Other ) Tj 51.428571 0 0 51.428571 0 2828.557895 Tm 25.277778 0 Td 49.074074 Tz (bilayer ) Tj 2.411111 0 Td 45.910494 Tz (vesicle-like ) Tj 3.616667 0 Td 46.990741 Tz (structures ) Tj 3.188889 0 Td 54.012346 Tz (can ) Tj 1.322222 0 Td 56.712963 Tz (be ) Tj 1.030556 0 Td 55.092593 Tz (used ) Tj 1.633333 0 Td 50.231481 Tz (as ) Tj 0.913889 0 Td 58.333333 Tz (a ) Tj 0.680556 0 Td 49.331276 Tz (template, ) Tj 51.428571 0 0 51.428571 0 2788.297674 Tm 25.297222 0 Td 51.49177 Tz (including ) Tj 2.877778 0 Td 59.143519 Tz (polymersomes ) Tj 4.394444 0 Td 53.472222 Tz (prepared ) Tj 2.741667 0 Td 56.712963 Tz (from ) Tj 1.555556 0 Td 52.314815 Tz (diblock ) Tj 2.313889 0 Td 53.914141 Tz (copolymers. ) Tj 51.428571 0 0 51.428571 0 2727.591512 Tm 26.036111 0 Td 48.611111 Tz (In ) Tj 0.894444 0 Td 46.296296 Tz (certain ) Tj 2.216667 0 Td 57.253086 Tz (embodiments, ) Tj 4.433333 0 Td 46.990741 Tz (vesicles ) Tj 2.547222 0 Td 54.282407 Tz (such ) Tj 1.594444 0 Td 51.851852 Tz (as ) Tj 0.933333 0 Td 54.012346 Tz (liposomes ) Tj 3.208333 0 Td 50.771605 Tz (are ) Tj 51.428571 0 0 51.428571 0 2685.207824 Tm 25.297222 0 Td 53.06713 Tz (prepared ) Tj 2.722222 0 Td 58.333333 Tz (by ) Tj 0.913889 0 Td 57.87037 Tz (methods ) Tj 2.605556 0 Td 65.462963 Tz (known ) Tj 2.158333 0 Td 45.37037 Tz (in ) Tj 0.7 0 Td 51.851852 Tz (the ) Tj 1.069444 0 Td 39.699074 Tz (art. ) Tj 1.186111 0 Td 57.973251 Tz (Exemplary ) Tj 3.305556 0 Td 48.148148 Tz (classes ) Tj 2.216667 0 Td 56.712963 Tz (of ) Tj 51.428571 0 0 51.428571 0 2644.170388 Tm 25.297222 0 Td 44.722222 Tz (lipid ) Tj 1.477778 0 Td 58.657407 Tz (components ) Tj 3.655556 0 Td 46.990741 Tz (that ) Tj 1.283333 0 Td 57.523148 Tz (form ) Tj 1.575 0 Td 51.527778 Tz (liposomes, ) Tj 3.266667 0 Td 50.771605 Tz (including ) Tj 2.897222 0 Td 50.673401 Tz (unilamellar ) Tj 51.428571 0 0 51.428571 0 2597.731001 Tm 25.297222 0 Td 52.175926 Tz (liposomes, ) Tj 3.286111 0 Td 45.37037 Tz (in ) Tj 0.7 0 Td 56.481481 Tz (aqueous ) Tj 2.527778 0 Td 54.552469 Tz (environments ) Tj 4.083333 0 Td 49.691358 Tz (are ) Tj 1.05 0 Td 64.814815 Tz (known ) Tj 2.119444 0 Td 43.75 Tz (in ) Tj 0.7 0 Td 50.771605 Tz (the ) Tj 1.011111 0 Td 44.290123 Tz (art ) Tj 0.933333 0 Td 59.41358 Tz (and ) Tj 51.428571 0 0 51.428571 0 2553.568032 Tm 25.297222 0 Td 55.092593 Tz (can ) Tj 1.225 0 Td 59.953704 Tz (be ) Tj 0.952778 0 Td 48.611111 Tz (selected ) Tj 2.566667 0 Td 58.333333 Tz (by ) Tj 0.952778 0 Td 58.333333 Tz (one ) Tj 1.283333 0 Td 58.333333 Tz (of ) Tj 0.836111 0 Td 51.041667 Tz (ordinary ) Tj 2.722222 0 Td 40.833333 Tz (skill ) Tj 1.458333 0 Td 46.990741 Tz (in ) Tj 0.777778 0 Td 51.851852 Tz (the ) Tj 1.127778 0 Td 44.290123 Tz (art ) Tj 1.030556 0 Td 52.5 Tz (using ) Tj 1.827778 0 Td 56.712963 Tz (no ) Tj 51.428571 0 0 51.428571 0 2513.284848 Tm 25.297222 0 Td 62.384259 Tz (more ) Tj 1.711111 0 Td 51.851852 Tz (than ) Tj 1.516667 0 Td 48.611111 Tz (routine ) Tj 2.255556 0 Td 50.636574 Tz (experimentation. ) Tj 5.152778 0 Td 59.143519 Tz (Examples ) Tj 3.111111 0 Td 55.092593 Tz (of ) Tj 0.816667 0 Td 60.358796 Tz (liposome ) Tj 51.428571 0 0 51.428571 0 2468.096386 Tm 25.297222 0 Td 56.018519 Tz (forming ) Tj 2.644444 0 Td 48.611111 Tz (materials ) Tj 2.916667 0 Td 50.925926 Tz (include ) Tj 2.391667 0 Td 51.851852 Tz (phosphatidylcholine ) Tj 6.144444 0 Td 60.493827 Tz (and ) Tj 1.341667 0 Td 56.17284 Tz (deriva ) Tj 51.428571 0 0 51.428571 0 2422.99455 Tm 25.277778 0 Td 42.669753 Tz (tives, ) Tj 1.963889 0 Td 54.282407 Tz (such ) Tj 1.711111 0 Td 48.611111 Tz (as ) Tj 1.011111 0 Td 73.240741 Tz (DMPC, ) Tj 2.625 0 Td 58.333333 Tz (and ) Tj 1.438889 0 Td 50.555556 Tz (other ) Tj 1.886111 0 Td 53.914141 Tz (amphiphiles ) Tj 3.966667 0 Td 45.37037 Tz (that ) Tj 1.458333 0 Td 59.953704 Tz (form ) Tj 51.428571 0 0 51.428571 0 2382.788018 Tm 25.297222 0 Td 47.395833 Tz (vesicles ) Tj 2.488889 0 Td 49.907407 Tz (\(including ) Tj 3.169444 0 Td 56.893004 Tz (dioctadecyldimethylammonium ) Tj 9.430556 0 Td 49.826389 Tz (chloride ) Tj 51.428571 0 0 51.428571 0 2338.1712 Tm 25.297222 0 Td 58.333333 Tz (and ) Tj 1.225 0 Td 51.851852 Tz (other ) Tj 1.711111 0 Td 56.924316 Tz (dialkyldimethylammonium ) Tj 8.069444 0 Td 40.277778 Tz (salts\). ) Tj 51.428571 0 0 51.428571 0 2281.904821 Tm 26.016667 0 Td 63.734568 Tz (The ) Tj 1.263889 0 Td 50.378788 Tz (preparation ) Tj 3.5 0 Td 55.092593 Tz (of ) Tj 0.719444 0 Td 50.771605 Tz (the ) Tj 1.030556 0 Td 58.796296 Tz (polymer ) Tj 2.605556 0 Td 53.472222 Tz (nanocapsules ) Tj 4.044444 0 Td 53.472222 Tz (of ) Tj 0.7 0 Td 50.771605 Tz (the ) Tj 1.069444 0 Td 60.277778 Tz (inven ) Tj 51.428571 0 0 51.428571 0 2236.031123 Tm 25.277778 0 Td 46.990741 Tz (tion ) Tj 1.536111 0 Td 55.092593 Tz (can ) Tj 1.380556 0 Td 58.333333 Tz (be ) Tj 1.069444 0 Td 56.532922 Tz (performed ) Tj 3.441667 0 Td 43.75 Tz (in ) Tj 0.913889 0 Td 56.944444 Tz (aqueous ) Tj 2.8 0 Td 46.342593 Tz (Solutions, ) Tj 3.169444 0 Td 58.981481 Tz (which ) Tj 2.158333 0 Td 57.253086 Tz (can ) Tj 51.428571 0 0 51.428571 0 2192.427071 Tm 25.297222 0 Td 48.935185 Tz (optionally ) Tj 3.072222 0 Td 50.925926 Tz (include ) Tj 2.275 0 Td 50.925926 Tz (water-miscible ) Tj 4.413889 0 Td 50.462963 Tz (organic ) Tj 2.255556 0 Td 46.8107 Tz (solvents, ) Tj 2.663889 0 Td 58.981481 Tz (which ) Tj 1.905556 0 Td 49.691358 Tz (are ) Tj 51.428571 0 0 51.428571 0 2150.456996 Tm 25.297222 0 Td 49.691358 Tz (generally ) Tj 3.072222 0 Td 49.016204 Tz (selected ) Tj 2.722222 0 Td 45.37037 Tz (to ) Tj 0.952778 0 Td 52.256944 Tz (maintain ) Tj 2.897222 0 Td 55.902778 Tz (complete ) Tj 3.072222 0 Td 46.548822 Tz (miscibility ) Tj 3.461111 0 Td 54.282407 Tz (with ) Tj 51.428571 0 0 51.428571 0 2106.565707 Tm 25.277778 0 Td 55.092593 Tz (water ) Tj 1.886111 0 Td 46.759259 Tz (\(single ) Tj 2.216667 0 Td 46.990741 Tz (liquid ) Tj 1.925 0 Td 55.740741 Tz (phase ) Tj 1.925 0 Td 51.851852 Tz (or ) Tj 0.855556 0 Td 58.981481 Tz (monophase\) ) Tj 3.811111 0 Td 55.092593 Tz (under ) Tj 1.866667 0 Td 49.691358 Tz (the ) Tj 1.147222 0 Td 61.574074 Tz (condi ) Tj 51.428571 0 0 51.428571 0 2060.457286 Tm 25.277778 0 Td 47.314815 Tz (tions ) Tj 1.633333 0 Td 51.388889 Tz (chosen, ) Tj 2.352778 0 Td 40.833333 Tz (e.g., ) Tj 1.419444 0 Td 53.472222 Tz (over ) Tj 1.438889 0 Td 49.691358 Tz (the ) Tj 1.069444 0 Td 46.990741 Tz (entire ) Tj 1.866667 0 Td 53.148148 Tz (range ) Tj 1.788889 0 Td 56.712963 Tz (from ) Tj 1.575 0 Td 53.796296 Tz (about ) Tj 1.788889 0 Td 49.421296 Tz (0.01 ) Tj 1.477778 0 Td 43.75 Tz (Vol. ) Tj 51.428571 0 0 51.428571 0 2017.811594 Tm 25.297222 0 Td 97.222222 Tz (% ) Tj 0.738889 0 Td 59.953704 Tz (up ) Tj 0.894444 0 Td 43.75 Tz (to ) Tj 0.661111 0 Td 55.092593 Tz (about ) Tj 1.788889 0 Td 59.953704 Tz (60 ) Tj 0.894444 0 Td 54.552469 Tz (vol.%. ) Tj 2.177778 0 Td 58.333333 Tz (Examples ) Tj 2.936111 0 Td 56.712963 Tz (of ) Tj 0.758333 0 Td 51.388889 Tz (water-miscible ) Tj 4.452778 0 Td 50.925926 Tz (organic ) Tj 51.428571 0 0 51.428571 0 1974.414545 Tm 25.316667 0 Td 48.611111 Tz (Solvents ) Tj 2.547222 0 Td 51.388889 Tz (include ) Tj 2.333333 0 Td 50.636574 Tz (alcohols ) Tj 2.625 0 Td 60.493827 Tz (and ) Tj 1.283333 0 Td 47.685185 Tz (aprotic ) Tj 2.216667 0 Td 46.450617 Tz (solvents. ) Tj 2.780556 0 Td 59.143519 Tz (Examples ) Tj 3.072222 0 Td 56.712963 Tz (of ) Tj 51.428571 0 0 51.428571 0 1929.744516 Tm 25.297222 0 Td 50.925926 Tz (alcohol ) Tj 2.586111 0 Td 49.016204 Tz (Solvents ) Tj 2.819444 0 Td 50.925926 Tz (include ) Tj 2.605556 0 Td 52.932099 Tz (methanol, ) Tj 3.305556 0 Td 47.800926 Tz (ethanol. ) Tj 2.838889 0 Td 49.789562 Tz (1-propanol, ) Tj 51.428571 0 0 51.428571 0 1888.869159 Tm 25.297222 0 Td 50.968013 Tz (2-propanol, ) Tj 3.538889 0 Td 49.259259 Tz (2-butanol, ) Tj 3.130556 0 Td 45.619658 Tz (tert-butanol, ) Tj 3.713889 0 Td 51.851852 Tz (ethylene ) Tj 2.625 0 Td 48.148148 Tz (glycol, ) Tj 2.197222 0 Td 53.703704 Tz (diethyl ) Tj 51.428571 0 0 51.428571 0 1847.87703 Tm 25.297222 0 Td 56.17284 Tz (ene ) Tj 1.108333 0 Td 47.685185 Tz (glycol, ) Tj 2.119444 0 Td 54.012346 Tz (propylene ) Tj 2.994444 0 Td 47.685185 Tz (glycol, ) Tj 2.1 0 Td 47.530864 Tz (glycerol, ) Tj 2.741667 0 Td 51.244213 Tz (methylcelloSolve ) Tj 5.055556 0 Td 55.902778 Tz (\(eth ) Tj 51.428571 0 0 51.428571 0 1804.088968 Tm 25.277778 0 Td 53.148148 Tz (ylene ) Tj 1.788889 0 Td 50.231481 Tz (glycol ) Tj 2.061111 0 Td 60.601852 Tz (monomethyl ) Tj 3.85 0 Td 44.444444 Tz (ether\), ) Tj 2.1 0 Td 50 Tz (methylcarbitol ) Tj 4.413889 0 Td 49.789562 Tz (\(diethylene ) Tj 51.428571 0 0 51.428571 0 1755.714976 Tm 25.297222 0 Td 50.231481 Tz (glycol ) Tj 2.002778 0 Td 60.925926 Tz (monomethyl ) Tj 3.811111 0 Td 48.070988 Tz (ether\) ) Tj 1.866667 0 Td 59.41358 Tz (and ) Tj 1.263889 0 Td 48.611111 Tz (the ) Tj 1.05 0 Td 40.833333 Tz (like. ) Tj 1.438889 0 Td 54.372428 Tz (Methanol, ) Tj 3.091667 0 Td 51.388889 Tz (ethanol ) Tj 2.333333 0 Td 53.472222 Tz (or ) Tj 51.428571 0 0 51.428571 0 1714.17896 Tm 25.277778 0 Td 46.990741 Tz (tert-butanol ) Tj 3.616667 0 Td 49.691358 Tz (are ) Tj 1.108333 0 Td 47.962963 Tz (preferred, ) Tj 3.111111 0 Td 46.180556 Tz (particularly ) Tj 3.577778 0 Td 48.206019 Tz (ethanol. ) Tj 2.547222 0 Td 52.314815 Tz (Aprotic ) Tj 2.430556 0 Td 60.493827 Tz (sol ) Tj 48.571429 0 0 48.571429 0 1668 Tm 26.785294 0 Td 53.529412 Tz (vents ) Tj 1.811765 0 Td 53.921569 Tz (include ) Tj 2.45 0 Td 60.04902 Tz (an ) Tj 0.885294 0 Td 48.039216 Tz (ether, ) Tj 1.914706 0 Td 60.04902 Tz (an ) Tj 0.905882 0 Td 45.179739 Tz (ester, ) Tj 1.811765 0 Td 54.901961 Tz (a ) Tj 0.535294 0 Td 53.431373 Tz (ketone, ) Tj 2.408824 0 Td 61.764706 Tz (a ) Tj 0.576471 0 Td 41.605392 Tz (nitrile, ) Tj 2.182353 0 Td 60.04902 Tz (an ) Tj 0.926471 0 Td 57.189542 Tz (amide, ) Tj 52.857143 0 0 52.857143 0 1624.984516 Tm 24.613514 0 Td 52.027027 Tz (or ) Tj 0.87027 0 Td 53.603604 Tz (a ) Tj 0.643243 0 Td 46.351351 Tz (sulfoxide. ) Tj 3.083784 0 Td 62.012012 Tz (The ) Tj 1.4 0 Td 46.846847 Tz (aprotic ) Tj 2.27027 0 Td 49.099099 Tz (solvent ) Tj 2.345946 0 Td 37.837838 Tz (is ) Tj 0.756757 0 Td 48.558559 Tz (preferably ) Tj 3.216216 0 Td 50.45045 Tz (ethylene ) Tj 51.428571 0 0 51.428571 0 1584.396135 Tm 25.297222 0 Td 50.231481 Tz (glycol ) Tj 2.002778 0 Td 53.472222 Tz (dimethyl ) Tj 2.761111 0 Td 44.830247 Tz (ether, ) Tj 1.788889 0 Td 51.446759 Tz (ethylene ) Tj 2.663889 0 Td 50.231481 Tz (glycol ) Tj 2.002778 0 Td 47.222222 Tz (diethyl ) Tj 2.177778 0 Td 44.830247 Tz (ether, ) Tj 1.827778 0 Td 53.240741 Tz (diethyl ) Tj 51.428571 0 0 51.428571 0 1538.865882 Tm 25.297222 0 Td 51.851852 Tz (eneglycol ) Tj 3.013889 0 Td 53.06713 Tz (dimethyl ) Tj 2.722222 0 Td 44.830247 Tz (ether, ) Tj 1.788889 0 Td 51.851852 Tz (dioxane, ) Tj 2.644444 0 Td 49.016204 Tz (tetrahydrofuran, ) Tj 4.9 0 Td 49.421296 Tz (acetone, ) Tj 51.428571 0 0 51.428571 0 1495.427918 Tm 25.297222 0 Td 51.671811 Tz (methylethylketone, ) Tj 5.697222 0 Td 44.373219 Tz (acetonitrile, ) Tj 3.577778 0 Td 55.092593 Tz (dimethylformamide, ) Tj 6.086111 0 Td 53.472222 Tz (or ) Tj 0.738889 0 Td 75.617284 Tz (dim ) Tj 51.428571 0 0 51.428571 0 1450.749373 Tm 25.297222 0 Td 47.962963 Tz (ethylsulfoxide. ) Tj 4.647222 0 Td 56.388889 Tz (Other ) Tj 1.983333 0 Td 49.016204 Tz (solvents ) Tj 2.683333 0 Td 51.388889 Tz (include ) Tj 2.469444 0 Td 56.712963 Tz (amines ) Tj 2.391667 0 Td 39.429012 Tz (\(e.g., ) Tj 1.75 0 Td 64.00463 Tz (buty ) Tj 51.428571 0 0 51.428571 0 1404.950197 Tm 25.297222 0 Td 52.777778 Tz (lamine\) ) Tj 2.527778 0 Td 59.41358 Tz (and ) Tj 1.380556 0 Td 51.388889 Tz (organic ) Tj 2.488889 0 Td 49.259259 Tz (acids ) Tj 1.827778 0 Td 40.509259 Tz (\(e.g., ) Tj 1.769444 0 Td 47.530864 Tz (acetic ) Tj 2.002778 0 Td 45.37037 Tz (acid\). ) Tj 2.022222 0 Td 45.37037 Tz (In ) Tj 0.855556 0 Td 47.530864 Tz (addition, ) Tj 51.428571 0 0 51.428571 0 1360.267925 Tm 25.277778 0 Td 48.611111 Tz (buffers ) Tj 2.236111 0 Td 59.41358 Tz (and ) Tj 1.244444 0 Td 49.907407 Tz (other ) Tj 1.633333 0 Td 48.251029 Tz (additives ) Tj 2.838889 0 Td 66.975309 Tz (may ) Tj 1.380556 0 Td 58.333333 Tz (be ) Tj 0.875 0 Td 50.555556 Tz (used, ) Tj 1.691667 0 Td 41.481481 Tz (e.g., ) Tj 1.4 0 Td 51.851852 Tz (as ) Tj 0.816667 0 Td 37.268519 Tz (is ) Tj 0.661111 0 Td 64.814815 Tz (known ) Tj 2.158333 0 Td 46.990741 Tz (in ) Tj 40 0 0 40 0 1324 Tm 32.5 0 Td 65.277778 Tz (the ) Tj 1.4 0 Td 48.958333 Tz (art. ) Tj 51.428571 0 0 51.428571 0 1262.998675 Tm 26.016667 0 Td 63.734568 Tz (The ) Tj 1.380556 0 Td 53.148148 Tz (metal ) Tj 1.866667 0 Td 49.421296 Tz (nanoparticle ) Tj 3.772222 0 Td 54.012346 Tz (can ) Tj 1.225 0 Td 58.333333 Tz (be ) Tj 0.913889 0 Td 49.016204 Tz (selected ) Tj 2.586111 0 Td 57.523148 Tz (from ) Tj 1.633333 0 Td 51.851852 Tz (a ) Tj 0.583333 0 Td 46.296296 Tz (variety ) Tj 2.158333 0 Td 59.953704 Tz (of ) Tj 51.428571 0 0 51.428571 0 1221.336516 Tm 25.297222 0 Td 49.537037 Tz (metals, ) Tj 2.216667 0 Td 40.833333 Tz (e.g., ) Tj 1.361111 0 Td 41.666667 Tz (silver, ) Tj 1.886111 0 Td 51.131687 Tz (platinum, ) Tj 2.897222 0 Td 51.851852 Tz (palladium, ) Tj 3.247222 0 Td 58.333333 Tz (and ) Tj 1.166667 0 Td 48.611111 Tz (gold. ) Tj 1.672222 0 Td 45.37037 Tz (In ) Tj 0.680556 0 Td 48.206019 Tz (general, ) Tj 51.428571 0 0 51.428571 0 1175.088916 Tm 25.297222 0 Td 51.851852 Tz (a ) Tj 0.505556 0 Td 49.537037 Tz (desired ) Tj 2.255556 0 Td 52.5 Tz (metal ) Tj 1.788889 0 Td 49.691358 Tz (nanoparticle ) Tj 3.733333 0 Td 56.17284 Tz (can ) Tj 1.166667 0 Td 58.333333 Tz (be ) Tj 0.875 0 Td 58.333333 Tz (formed ) Tj 2.255556 0 Td 53.877315 Tz (provided ) Tj 2.741667 0 Td 46.180556 Tz (that ) Tj 1.244444 0 Td 50.771605 Tz (the ) Tj 51.428571 0 0 51.428571 0 1130.845399 Tm 25.297222 0 Td 52.211934 Tz (elemental ) Tj 3.033333 0 Td 52.5 Tz (metal ) Tj 1.769444 0 Td 53.472222 Tz (does ) Tj 1.516667 0 Td 50.771605 Tz (not ) Tj 1.088889 0 Td 46.866097 Tz (substantially ) Tj 3.888889 0 Td 46.018519 Tz (react ) Tj 1.555556 0 Td 52.662037 Tz (with ) Tj 1.477778 0 Td 48.611111 Tz (the ) Tj 1.069444 0 Td 49.537037 Tz (solvent ) Tj 51.428571 0 0 51.428571 0 1088.084088 Tm 25.316667 0 Td 51.851852 Tz (system, ) Tj 2.45 0 Td 40.833333 Tz (e.g., ) Tj 1.516667 0 Td 54.282407 Tz (does ) Tj 1.613889 0 Td 49.691358 Tz (not ) Tj 1.147222 0 Td 47.314815 Tz (react ) Tj 1.691667 0 Td 52.662037 Tz (with ) Tj 1.536111 0 Td 55.092593 Tz (water ) Tj 1.905556 0 Td 50.231481 Tz (or ) Tj 0.836111 0 Td 56.944444 Tz (aqueous ) Tj 2.663889 0 Td 50 Tz (solvent ) Tj 51.428571 0 0 51.428571 0 1043.528967 Tm 25.316667 0 Td 50.636574 Tz (systems. ) Tj 2.625 0 Td 69.135802 Tz (One ) Tj 1.419444 0 Td 56.712963 Tz (of ) Tj 0.777778 0 Td 51.041667 Tz (ordinary ) Tj 2.663889 0 Td 40.833333 Tz (skill ) Tj 1.438889 0 Td 43.75 Tz (in ) Tj 0.719444 0 Td 48.611111 Tz (the ) Tj 1.05 0 Td 43.209877 Tz (art ) Tj 0.952778 0 Td 56.17284 Tz (can ) Tj 1.225 0 Td 44.830247 Tz (select ) Tj 1.788889 0 Td 55.092593 Tz (a ) Tj 0.525 0 Td 47.395833 Tz (suitable ) Tj 51.428571 0 0 51.428571 0 1001.995221 Tm 25.297222 0 Td 53.796296 Tz (metal ) Tj 1.730556 0 Td 53.652263 Tz (according ) Tj 3.033333 0 Td 45.37037 Tz (to ) Tj 0.680556 0 Td 50.771605 Tz (the ) Tj 1.05 0 Td 52.256944 Tz (intended ) Tj 2.644444 0 Td 55.092593 Tz (use ) Tj 1.127778 0 Td 55.092593 Tz (of ) Tj 0.719444 0 Td 50.771605 Tz (the ) Tj 1.088889 0 Td 51.353276 Tz (nanocapsules, ) Tj 4.141667 0 Td 40.833333 Tz (e.g., ) Tj 51.428571 0 0 51.428571 0 957.961259 Tm 25.297222 0 Td 50.231481 Tz (as ) Tj 0.738889 0 Td 44.722222 Tz (catalysts, ) Tj 2.819444 0 Td 51.851852 Tz (as ) Tj 0.758333 0 Td 48.905724 Tz (therapeutic ) Tj 3.383333 0 Td 48.611111 Tz (agents, ) Tj 2.158333 0 Td 51.851852 Tz (as ) Tj 0.777778 0 Td 48.206019 Tz (sensors, ) Tj 2.430556 0 Td 60.493827 Tz (and ) Tj 1.225 0 Td 49.691358 Tz (the ) Tj 1.05 0 Td 40.833333 Tz (like. ) Tj 1.361111 0 Td 61.574074 Tz (To ) Tj 51.428571 0 0 51.428571 0 915.973072 Tm 25.297222 0 Td 52.314815 Tz (prepare ) Tj 2.430556 0 Td 51.851852 Tz (metal ) Tj 1.808333 0 Td 49.109687 Tz (nanoparticles ) Tj 4.025 0 Td 53.652263 Tz (entrapped ) Tj 3.111111 0 Td 45.37037 Tz (in ) Tj 0.758333 0 Td 51.851852 Tz (a ) Tj 0.525 0 Td 54.372428 Tz (polymeric ) Tj 3.188889 0 Td 67.24537 Tz (nano ) Tj 51.428571 0 0 51.428571 0 870.906057 Tm 25.297222 0 Td 49.016204 Tz (capsule, ) Tj 2.508333 0 Td 51.851852 Tz (the ) Tj 1.108333 0 Td 53.148148 Tz (metal ) Tj 1.769444 0 Td 40.509259 Tz (is ) Tj 0.641667 0 Td 50.411523 Tz (generally ) Tj 2.877778 0 Td 54.282407 Tz (provided ) Tj 2.780556 0 Td 48.611111 Tz (as ) Tj 0.777778 0 Td 55.092593 Tz (a ) Tj 0.525 0 Td 51.851852 Tz (metal ) Tj 1.769444 0 Td 42.12963 Tz (salt ) Tj 1.166667 0 Td 51.851852 Tz (\(with ) Tj 51.428571 0 0 51.428571 0 825.03423 Tm 25.297222 0 Td 55.092593 Tz (a ) Tj 0.486111 0 Td 52.5 Tz (metal ) Tj 1.75 0 Td 47.222222 Tz (cation\) ) Tj 2.119444 0 Td 46.990741 Tz (in ) Tj 0.719444 0 Td 49.691358 Tz (the ) Tj 1.011111 0 Td 56.481481 Tz (aqueous ) Tj 2.508333 0 Td 55.740741 Tz (phase ) Tj 1.808333 0 Td 47.800926 Tz (\(the ) Tj 1.283333 0 Td 53.148148 Tz (metal ) Tj 1.75 0 Td 42.12963 Tz (salt ) Tj 1.147222 0 Td 58.333333 Tz (must ) Tj 1.536111 0 Td 56.712963 Tz (have ) Tj 51.428571 0 0 51.428571 0 780.548077 Tm 25.297222 0 Td 43.75 Tz (at ) Tj 0.661111 0 Td 41.319444 Tz (lest ) Tj 1.127778 0 Td 64.00463 Tz (some ) Tj 1.652778 0 Td 54.444444 Tz (water ) Tj 1.730556 0 Td 43.479938 Tz (solubility\). ) Tj 3.266667 0 Td 64.814815 Tz (The ) Tj 1.302778 0 Td 54.282407 Tz (metalion ) Tj 2.741667 0 Td 40.509259 Tz (is ) Tj 0.622222 0 Td 51.851852 Tz (then ) Tj 1.380556 0 Td 54.62963 Tz (reduced ) Tj 2.391667 0 Td 46.990741 Tz (to ) Tj 51.428571 0 0 51.428571 0 739.096774 Tm 25.297222 0 Td 56.712963 Tz (an ) Tj 0.933333 0 Td 52.572016 Tz (elemental ) Tj 3.130556 0 Td 52.5 Tz (metal ) Tj 1.886111 0 Td 49.691358 Tz (nanoparticle ) Tj 3.869444 0 Td 43.75 Tz (in ) Tj 0.816667 0 Td 42.939815 Tz (situ ) Tj 1.302778 0 Td 53.703704 Tz (through ) Tj 2.527778 0 Td 50.771605 Tz (the ) Tj 1.147222 0 Td 55.092593 Tz (use ) Tj 1.263889 0 Td 56.712963 Tz (of ) Tj 51.428571 0 0 51.428571 0 694.064209 Tm 25.297222 0 Td 46.450617 Tz (free-radical ) Tj 3.519444 0 Td 53.796296 Tz (redox ) Tj 1.730556 0 Td 49.583333 Tz (chemistry. ) Tj 3.091667 0 Td 63.734568 Tz (The ) Tj 1.283333 0 Td 53.148148 Tz (metal ) Tj 1.711111 0 Td 42.939815 Tz (salt ) Tj 1.147222 0 Td 48.206019 Tz (selected ) Tj 2.469444 0 Td 45.37037 Tz (will ) Tj 1.283333 0 Td 51.851852 Tz (vary ) Tj 51.428571 0 0 51.428571 0 651.338346 Tm 25.297222 0 Td 53.292181 Tz (according ) Tj 3.091667 0 Td 46.990741 Tz (to ) Tj 0.816667 0 Td 46.759259 Tz (factors ) Tj 2.236111 0 Td 54.282407 Tz (such ) Tj 1.555556 0 Td 50.231481 Tz (as ) Tj 0.836111 0 Td 49.691358 Tz (the ) Tj 1.127778 0 Td 50.462963 Tz (desired ) Tj 2.372222 0 Td 53.148148 Tz (metal ) Tj 1.847222 0 Td 49.96142 Tz (nanoparticle ) Tj 51.428571 0 0 51.428571 0 608.977591 Tm 25.297222 0 Td 58.333333 Tz (and ) Tj 1.4 0 Td 49.691358 Tz (the ) Tj 1.263889 0 Td 45.37037 Tz (solubility ) Tj 3.111111 0 Td 58.333333 Tz (of ) Tj 0.952778 0 Td 49.691358 Tz (the ) Tj 1.263889 0 Td 42.12963 Tz (salt ) Tj 1.380556 0 Td 45.37037 Tz (in ) Tj 0.894444 0 Td 49.691358 Tz (the ) Tj 1.244444 0 Td 56.944444 Tz (aqueous ) Tj 2.761111 0 Td 49.691358 Tz (phase. ) Tj 2.236111 0 Td 55.092593 Tz (For ) Tj 51.428571 0 0 51.428571 0 564.038605 Tm 25.297222 0 Td 54.6875 Tz (example, ) Tj 2.858333 0 Td 45.37037 Tz (silver ) Tj 1.847222 0 Td 43.981481 Tz (nitrate ) Tj 2.041667 0 Td 55.092593 Tz (can ) Tj 1.225 0 Td 58.333333 Tz (be ) Tj 0.913889 0 Td 55.902778 Tz (used ) Tj 1.555556 0 Td 48.611111 Tz (for ) Tj 1.05 0 Td 50.084175 Tz (preparation ) Tj 3.558333 0 Td 56.712963 Tz (of ) Tj 0.836111 0 Td 44.830247 Tz (silver ) Tj 51.428571 0 0 51.428571 0 520.306024 Tm 25.297222 0 Td 48.148148 Tz (nanoparticles; ) Tj 4.238889 0 Td 54.282407 Tz (gold ) Tj 1.458333 0 Td 42.777778 Tz (salts ) Tj 1.477778 0 Td 54.282407 Tz (such ) Tj 1.458333 0 Td 51.851852 Tz (as ) Tj 0.758333 0 Td 55.092593 Tz (gold ) Tj 1.477778 0 Td 49.826389 Tz (chloride ) Tj 2.566667 0 Td 67.592593 Tz (\(HAuCl\) ) Tj 3.013889 0 Td 57.253086 Tz (can ) Tj 51.428571 0 0 51.428571 0 478.492462 Tm 25.277778 0 Td 59.953704 Tz (be ) Tj 0.952778 0 Td 55.902778 Tz (used ) Tj 1.555556 0 Td 46.990741 Tz (to ) Tj 0.816667 0 Td 52.314815 Tz (prepare ) Tj 2.411111 0 Td 55.092593 Tz (gold ) Tj 1.575 0 Td 47.916667 Tz (nanoparticles. ) Tj 4.316667 0 Td 62.222222 Tz (Mixed ) Tj 2.158333 0 Td 47.800926 Tz (metallic ) Tj 2.547222 0 Td 63.734568 Tz (par ) Tj 51.428571 0 0 51.428571 0 431.702128 Tm 25.277778 0 Td 42.669753 Tz (ticles ) Tj 1.730556 0 Td 55.092593 Tz (can ) Tj 1.186111 0 Td 47.800926 Tz (also ) Tj 1.361111 0 Td 56.712963 Tz (be ) Tj 0.836111 0 Td 53.472222 Tz (prepared ) Tj 2.722222 0 Td 61.574074 Tz (by ) Tj 0.952778 0 Td 52.932099 Tz (use ) Tj 1.127778 0 Td 56.712963 Tz (of ) Tj 0.777778 0 Td 53.06713 Tz (mixtures ) Tj 2.761111 0 Td 55.092593 Tz (of ) Tj 0.797222 0 Td 52.5 Tz (metal ) Tj 1.75 0 Td 40.509259 Tz (salts. ) Tj 51.428571 0 0 51.428571 0 377.725095 Tm 26.036111 0 Td 49.691358 Tz (Selection ) Tj 2.877778 0 Td 56.712963 Tz (of ) Tj 0.777778 0 Td 55.092593 Tz (an ) Tj 0.855556 0 Td 50.378788 Tz (appropriate ) Tj 3.480556 0 Td 46.180556 Tz (free-radical ) Tj 3.519444 0 Td 43.209877 Tz (initiator ) Tj 2.508333 0 Td 47.530864 Tz (for ) Tj 0.991667 0 Td 55.092593 Tz (use ) Tj 1.166667 0 Td 46.990741 Tz (in ) Tj 51.428571 0 0 51.428571 0 337.300126 Tm 25.277778 0 Td 50.771605 Tz (the ) Tj 1.166667 0 Td 54.444444 Tz (redox ) Tj 1.827778 0 Td 53.292181 Tz (chemistry ) Tj 3.111111 0 Td 59.953704 Tz (of ) Tj 0.836111 0 Td 49.691358 Tz (the ) Tj 1.166667 0 Td 51.851852 Tz (metal ) Tj 1.788889 0 Td 59.41358 Tz (and ) Tj 1.283333 0 Td 48.611111 Tz (for ) Tj 1.088889 0 Td 43.425926 Tz (initiation ) Tj 2.838889 0 Td 59.953704 Tz (of ) Tj 0.816667 0 Td 64.814815 Tz (poly ) Tj 51.428571 0 0 51.428571 0 294.192308 Tm 25.297222 0 Td 51.527778 Tz (merization ) Tj 3.227778 0 Td 38.888889 Tz (is ) Tj 0.602778 0 Td 46.990741 Tz (also ) Tj 1.283333 0 Td 50.231481 Tz (possible ) Tj 2.508333 0 Td 47.530864 Tz (for ) Tj 0.933333 0 Td 50.771605 Tz (the ) Tj 1.011111 0 Td 46.296296 Tz (skilled ) Tj 2.061111 0 Td 46.296296 Tz (artisan ) Tj 2.041667 0 Td 45.37037 Tz (in ) Tj 0.7 0 Td 55.902778 Tz (view ) Tj 1.497222 0 Td 53.472222 Tz (of ) Tj 0.719444 0 Td 49.691358 Tz (the ) Tj 51.428571 0 0 51.428571 0 252.261614 Tm 25.297222 0 Td 49.259259 Tz (disclosure ) Tj 3.111111 0 Td 47.222222 Tz (herein. ) Tj 2.197222 0 Td 52.256944 Tz (Separate ) Tj 2.683333 0 Td 42.777778 Tz (initiators ) Tj 2.741667 0 Td 56.17284 Tz (can ) Tj 1.186111 0 Td 58.333333 Tz (be ) Tj 0.875 0 Td 55.902778 Tz (used ) Tj 1.516667 0 Td 48.611111 Tz (for ) Tj 1.011111 0 Td 49.691358 Tz (the ) Tj 1.069444 0 Td 59.41358 Tz (for ) Tj 51.428571 0 0 51.428571 0 213.276753 Tm 25.297222 0 Td 55.632716 Tz (mation ) Tj 2.216667 0 Td 56.712963 Tz (of ) Tj 0.797222 0 Td 51.851852 Tz (metal ) Tj 1.808333 0 Td 49.109687 Tz (nanoparticles ) Tj 4.005556 0 Td 59.41358 Tz (and ) Tj 1.263889 0 Td 47.530864 Tz (for ) Tj 1.011111 0 Td 49.691358 Tz (the ) Tj 1.088889 0 Td 48.971193 Tz (synthesis ) Tj 2.858333 0 Td 55.092593 Tz (of ) Tj 0.797222 0 Td 67.24537 Tz (nano ) Tj 51.428571 0 0 51.428571 0 171.885714 Tm 25.297222 0 Td 48.971193 Tz (capsules, ) Tj 2.819444 0 Td 45.37037 Tz (if ) Tj 0.641667 0 Td 46.990741 Tz (desired. ) Tj ET Q endstream endobj 158 0 obj << /Length 1 >> stream q endstream endobj 159 0 obj << /Length 47343 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 62.857143 0 0 62.857143 0 3023 Tm 17.325 0 Td 83.522727 Tz (US ) Tj 1.209091 0 Td 57.744108 Tz (9.248,441 ) Tj 3.420455 0 Td 74.242424 Tz (B2 ) Tj 51.428571 0 0 51.428571 0 2968 Tm 14.875 0 Td 77.777778 Tz (7 ) Tj 38.571429 0 0 38.571429 0 2921 Tm 17.577778 0 Td 105.864198 Tz (EXAMPLES ) Tj 40 0 0 40 0 2834 Tm 8.175 0 Td 73.148148 Tz (Chemicals ) Tj 51.428571 0 0 51.428571 0 2787.871959 Tm 7.097222 0 Td 50.771605 Tz (All ) Tj 1.166667 0 Td 49.016204 Tz (solvents ) Tj 2.586111 0 Td 55.902778 Tz (used ) Tj 1.575 0 Td 59.143519 Tz (were ) Tj 1.691667 0 Td 75.347222 Tz (HPLC ) Tj 2.041667 0 Td 49.691358 Tz (grade. ) Tj 2.1 0 Td 51.49177 Tz (1,2-dimyristoyl-sn ) Tj 51.428571 0 0 51.428571 0 2748.356265 Tm 6.358333 0 Td 53.06713 Tz (glycero-3-phosphocholine ) Tj 8.108333 0 Td 70.216049 Tz (\(DMPC\) ) Tj 2.994444 0 Td 60.493827 Tz (was ) Tj 1.536111 0 Td 54.73251 Tz (purchased ) Tj 3.422222 0 Td 57.523148 Tz (from ) Tj 2.002778 0 Td 38.888889 Tz (5 ) Tj 51.428571 0 0 51.428571 0 2706.254321 Tm 6.358333 0 Td 52.932099 Tz (Avanti ) Tj 2.138889 0 Td 51.203704 Tz (Polar ) Tj 1.730556 0 Td 48.148148 Tz (Lipids, ) Tj 2.255556 0 Td 43.75 Tz (Inc. ) Tj 1.283333 0 Td 50.231481 Tz (as ) Tj 0.816667 0 Td 51.851852 Tz (a ) Tj 0.544444 0 Td 54.012346 Tz (dry ) Tj 1.147222 0 Td 54.62963 Tz (powder. ) Tj 2.508333 0 Td 52.662037 Tz (p-divinylbenzene ) Tj 51.428571 0 0 51.428571 0 2663.883212 Tm 6.377778 0 Td 59.953704 Tz (\(DVB\), ) Tj 2.45 0 Td 48.420479 Tz (tert-Butylstyrene ) Tj 5.230556 0 Td 48.206019 Tz (\(tBuSt\), ) Tj 2.644444 0 Td 55.497685 Tz (methanol ) Tj 2.936111 0 Td 60.493827 Tz (and ) Tj 1.380556 0 Td 58.738426 Tz (Sephadex ) Tj 51.428571 0 0 51.428571 0 2621.699758 Tm 6.358333 0 Td 62.384259 Tz (G-50 ) Tj 1.711111 0 Td 59.953704 Tz (\(medium\) ) Tj 3.111111 0 Td 58.333333 Tz (were ) Tj 1.594444 0 Td 55.092593 Tz (purchased ) Tj 3.188889 0 Td 59.143519 Tz (from ) Tj 1.652778 0 Td 53.009259 Tz (Sigma-Aldrich. ) Tj 4.744444 0 Td 79.938272 Tz (DVB ) Tj 51.428571 0 0 51.428571 0 2578.066986 Tm 6.358333 0 Td 58.333333 Tz (and ) Tj 1.186111 0 Td 55.740741 Tz (tRuSt ) Tj 1.808333 0 Td 58.333333 Tz (were ) Tj 1.536111 0 Td 54.012346 Tz (passed ) Tj 2.061111 0 Td 53.703704 Tz (through ) Tj 2.411111 0 Td 55.092593 Tz (an ) Tj 0.816667 0 Td 56.018519 Tz (alumina ) Tj 2.469444 0 Td 60.493827 Tz (column ) Tj 2.294444 0 Td 48.611111 Tz (to ) Tj 0.738889 0 Td 59.953704 Tz (remove ) Tj 51.428571 0 0 51.428571 0 2536.65614 Tm 6.338889 0 Td 50.771605 Tz (the ) Tj 1.030556 0 Td 43.75 Tz (inhibitor. ) Tj 2.8 0 Td 58.333333 Tz (Sephadex ) Tj 2.916667 0 Td 63.194444 Tz (G-50 ) Tj 1.633333 0 Td 55.092593 Tz (\(10 ) Tj 1.069444 0 Td 53.472222 Tz (g\) ) Tj 0.758333 0 Td 61.574074 Tz (was ) Tj 1.263889 0 Td 52.777778 Tz (swollen ) Tj 2.372222 0 Td 45.37037 Tz (in ) Tj 0.758333 0 Td 57.253086 Tz (120 ) Tj 1.166667 0 Td 82.638889 Tz (mL ) Tj 1.108333 0 Td 59.953704 Tz (of ) Tj 1.088889 0 Td 43.75 Tz (10 ) Tj 51.428571 0 0 51.428571 0 2495.814628 Tm 6.338889 0 Td 55.092593 Tz (water ) Tj 1.827778 0 Td 45.37037 Tz (in ) Tj 0.738889 0 Td 58.333333 Tz (a ) Tj 0.525 0 Td 48.611111 Tz (glass ) Tj 1.691667 0 Td 55.092593 Tz (screw-capped ) Tj 4.161111 0 Td 46.450617 Tz (bottle ) Tj 1.886111 0 Td 48.611111 Tz (for ) Tj 1.011111 0 Td 45.37037 Tz (at ) Tj 0.738889 0 Td 44.722222 Tz (least ) Tj 1.516667 0 Td 58.333333 Tz (5 ) Tj 0.544444 0 Td 62.654321 Tz (hat ) Tj 1.302778 0 Td 64.00463 Tz (room ) Tj 51.428571 0 0 51.428571 0 2455.131783 Tm 6.338889 0 Td 53.030303 Tz (temperature ) Tj 3.752778 0 Td 59.41358 Tz (and ) Tj 1.341667 0 Td 49.151235 Tz (stored ) Tj 2.002778 0 Td 46.990741 Tz (at ) Tj 0.836111 0 Td 64.00463 Tz (4C. ) Tj 1.847222 0 Td 44.074074 Tz (until ) Tj 1.633333 0 Td 49.826389 Tz (required ) Tj 2.644444 0 Td 48.611111 Tz (for ) Tj 1.127778 0 Td 46.180556 Tz (use. ) Tj 1.380556 0 Td 50.771605 Tz (All ) Tj 51.428571 0 0 51.428571 0 2411.301808 Tm 6.358333 0 Td 51.203704 Tz (other ) Tj 1.672222 0 Td 53.652263 Tz (chemicals ) Tj 3.111111 0 Td 58.333333 Tz (were ) Tj 1.613889 0 Td 50.771605 Tz (not ) Tj 1.108333 0 Td 47.222222 Tz (further ) Tj 2.119444 0 Td 47.395833 Tz (purified ) Tj 2.45 0 Td 51.851852 Tz (before ) Tj 2.061111 0 Td 46.180556 Tz (use. ) Tj 51.428571 0 0 51.428571 0 2370.65 Tm 6.358333 0 Td 64.166667 Tz (X-Ray ) Tj 2.138889 0 Td 48.316498 Tz (Diffraction ) Tj 3.402778 0 Td 58.603395 Tz (Measurements ) Tj 51.428571 0 0 51.428571 0 2331.70229 Tm 7.116667 0 Td 55.092593 Tz (For ) Tj 1.225 0 Td 86.419753 Tz (XRD ) Tj 1.827778 0 Td 51.851852 Tz (study ) Tj 1.866667 0 Td 53.20216 Tz (nanocapsules ) Tj 4.141667 0 Td 58.333333 Tz (were ) Tj 1.672222 0 Td 54.503367 Tz (resuspended ) Tj 3.869444 0 Td 43.75 Tz (in ) Tj 0.816667 0 Td 54.282407 Tz (ben- ) Tj 1.75 0 Td 43.75 Tz (15 ) Tj 48.571429 0 0 48.571429 0 2287 Tm 6.732353 0 Td 53.529412 Tz (Zene, ) Tj 1.791176 0 Td 64.052288 Tz (and ) Tj 1.338235 0 Td 49.358974 Tz (freeze-dried. ) Tj 51.428571 0 0 51.428571 0 2245.169655 Tm 7.097222 0 Td 84.259259 Tz (XRD ) Tj 1.847222 0 Td 49.074074 Tz (spectra ) Tj 2.391667 0 Td 59.143519 Tz (were ) Tj 1.730556 0 Td 49.331276 Tz (collected ) Tj 2.975 0 Td 58.333333 Tz (on ) Tj 1.05 0 Td 51.851852 Tz (a ) Tj 0.680556 0 Td 55.632716 Tz (Bruker ) Tj 2.352778 0 Td 69.675926 Tz (D8 ) Tj 1.127778 0 Td 61.574074 Tz (Advance ) Tj 51.428571 0 0 51.428571 0 2203.665835 Tm 6.358333 0 Td 56.388889 Tz (X-ray ) Tj 1.905556 0 Td 49.537037 Tz (diffractometer ) Tj 4.336111 0 Td 51.851852 Tz (using ) Tj 1.730556 0 Td 69.675926 Tz (Cu ) Tj 1.069444 0 Td 66.435185 Tz (Ka ) Tj 1.011111 0 Td 47.530864 Tz (radiation ) Tj 2.741667 0 Td 45.37037 Tz (at ) Tj 0.719444 0 Td 63.194444 Tz (40 ) Tj 0.933333 0 Td 71.296296 Tz (kV ) Tj 1.030556 0 Td 60.493827 Tz (and ) Tj 1.263889 0 Td 61.574074 Tz (40 ) Tj 51.428571 0 0 51.428571 0 2162.21181 Tm 6.358333 0 Td 69.135802 Tz (mA. ) Tj 1.497222 0 Td 64.814815 Tz (The ) Tj 1.419444 0 Td 45.959596 Tz (diffraction ) Tj 3.305556 0 Td 47.800926 Tz (patterns ) Tj 2.547222 0 Td 59.143519 Tz (were ) Tj 1.672222 0 Td 52.256944 Tz (obtained ) Tj 2.761111 0 Td 46.990741 Tz (in ) Tj 0.836111 0 Td 49.691358 Tz (the ) Tj 1.127778 0 Td 59.953704 Tz (20 ) Tj 1.030556 0 Td 54.282407 Tz (scan ) Tj 51.428571 0 0 51.428571 0 2121.692494 Tm 6.358333 0 Td 54.444444 Tz (range ) Tj 1.769444 0 Td 55.092593 Tz (30-75 ) Tj 2.158333 0 Td 52.662037 Tz (with ) Tj 1.419444 0 Td 55.092593 Tz (a ) Tj 0.525 0 Td 46.990741 Tz (step ) Tj 1.302778 0 Td 47.800926 Tz (size ) Tj 1.283333 0 Td 58.333333 Tz (of ) Tj 0.777778 0 Td 51.851852 Tz (0.05 ) Tj 1.419444 0 Td 59.41358 Tz (and ) Tj 1.186111 0 Td 55.092593 Tz (a ) Tj 0.525 0 Td 48.971193 Tz (time/step ) Tj 2.780556 0 Td 58.333333 Tz (of ) Tj 0.797222 0 Td 49.691358 Tz (0.2 ) Tj 1.05 0 Td 37.268519 Tz (s. ) Tj 0.933333 0 Td 45.37037 Tz (20 ) Tj 51.428571 0 0 51.428571 0 2080.361526 Tm 6.358333 0 Td 53.742284 Tz (Transmission ) Tj 4.141667 0 Td 49.826389 Tz (Electron ) Tj 2.586111 0 Td 57.685185 Tz (Microscopy ) Tj 3.655556 0 Td 66.759259 Tz (\(TEM\) ) Tj 51.428571 0 0 51.428571 0 2038.510638 Tm 7.097222 0 Td 84.259259 Tz (TEM ) Tj 1.847222 0 Td 56.712963 Tz (images ) Tj 2.372222 0 Td 59.143519 Tz (were ) Tj 1.691667 0 Td 53.06713 Tz (acquired ) Tj 2.819444 0 Td 63.194444 Tz (on ) Tj 1.05 0 Td 58.333333 Tz (a ) Tj 0.661111 0 Td 56.388889 Tz (JEOL, ) Tj 1.983333 0 Td 65.109428 Tz (JEM1200EXII ) Tj 51.428571 0 0 51.428571 0 1999.670644 Tm 6.358333 0 Td 53.324916 Tz (microscope. ) Tj 3.733333 0 Td 57.407407 Tz (Samples ) Tj 2.625 0 Td 58.333333 Tz (were ) Tj 1.594444 0 Td 48.611111 Tz (negatively ) Tj 3.130556 0 Td 49.074074 Tz (stained ) Tj 2.216667 0 Td 53.472222 Tz (with ) Tj 1.458333 0 Td 64.351852 Tz (phospho ) Tj 51.428571 0 0 51.428571 0 1956.761996 Tm 6.338889 0 Td 48.206019 Tz (tungstic ) Tj 2.488889 0 Td 51.851852 Tz (acid ) Tj 1.419444 0 Td 62.654321 Tz (\(pH ) Tj 1.302778 0 Td 47.800926 Tz (5.9\) ) Tj 1.341667 0 Td 58.333333 Tz (on ) Tj 0.913889 0 Td 55.092593 Tz (a ) Tj 0.525 0 Td 54.012346 Tz (carbon ) Tj 2.138889 0 Td 44.074074 Tz (grid. ) Tj 51.428571 0 0 51.428571 0 1917.35141 Tm 6.377778 0 Td 62.962963 Tz (Dynamic ) Tj 2.877778 0 Td 51.203704 Tz (Light ) Tj 1.730556 0 Td 48.935185 Tz (Scattering ) Tj 3.111111 0 Td 61.574074 Tz (\(DLS\) ) Tj 51.428571 0 0 51.428571 0 1873.814304 Tm 7.116667 0 Td 60.223765 Tz (Hydrodynamic ) Tj 4.647222 0 Td 53.06713 Tz (diameter ) Tj 2.858333 0 Td 57.523148 Tz (measurements ) Tj 4.452778 0 Td 59.143519 Tz (were ) Tj 1.730556 0 Td 56.532922 Tz (performed ) Tj 51.428571 0 0 51.428571 0 1828 Tm 6.358333 0 Td 61.574074 Tz (on ) Tj 0.894444 0 Td 55.092593 Tz (a ) Tj 0.505556 0 Td 58.333333 Tz (Malvern ) Tj 2.644444 0 Td 62.962963 Tz (Nano-ZS ) Tj 2.838889 0 Td 47.530864 Tz (Zetasizer ) Tj 2.722222 0 Td 55.497685 Tz (\(Malvern ) Tj 2.916667 0 Td 51.262626 Tz (Instruments ) Tj 3.597222 0 Td 44.074074 Tz (Ltd., ) Tj 51.428571 0 0 51.428571 0 1787.765133 Tm 6.358333 0 Td 50.123457 Tz (Worcestershire, ) Tj 4.705556 0 Td 50.231481 Tz (U.K.\). ) Tj 1.983333 0 Td 63.734568 Tz (The ) Tj 1.322222 0 Td 60.395623 Tz (Helium-Neon ) Tj 4.161111 0 Td 41.589506 Tz (laser, ) Tj 1.691667 0 Td 58.333333 Tz (4 ) Tj 0.583333 0 Td 81.018519 Tz (m ) Tj 0.563889 0 Td 61.574074 Tz (W, ) Tj 0.913889 0 Td 64.00463 Tz (oper ) Tj 51.428571 0 0 51.428571 0 1745.847059 Tm 6.358333 0 Td 46.990741 Tz (ates ) Tj 1.341667 0 Td 43.75 Tz (at ) Tj 0.777778 0 Td 56.17284 Tz (633 ) Tj 1.283333 0 Td 59.41358 Tz (nm, ) Tj 1.283333 0 Td 53.472222 Tz (with ) Tj 1.516667 0 Td 48.611111 Tz (the ) Tj 1.069444 0 Td 46.296296 Tz (scatter ) Tj 2.119444 0 Td 52.5 Tz (angle ) Tj 1.769444 0 Td 48.611111 Tz (fixed ) Tj 1.633333 0 Td 46.990741 Tz (at ) Tj 0.836111 0 Td 61.574074 Tz (173, ) Tj 1.672222 0 Td 59.41358 Tz (and ) Tj 1.283333 0 Td 49.691358 Tz (the ) Tj 51.428571 0 0 51.428571 0 1706.157895 Tm 6.338889 0 Td 53.030303 Tz (temperature ) Tj 3.733333 0 Td 46.990741 Tz (at ) Tj 0.816667 0 Td 55.092593 Tz (25 ) Tj 1.263889 0 Td 53.472222 Tz (C. ) Tj 0.933333 0 Td 63.194444 Tz (80 ) Tj 1.05 0 Td 63.194444 Tz (uL ) Tj 1.011111 0 Td 55.555556 Tz (samples ) Tj 2.625 0 Td 58.333333 Tz (were ) Tj 1.652778 0 Td 51.851852 Tz (taken ) Tj 1.847222 0 Td 57.523148 Tz (from ) Tj 1.672222 0 Td 49.691358 Tz (the ) Tj 51.428571 0 0 51.428571 0 1665.380711 Tm 6.358333 0 Td 48.611111 Tz (reaction ) Tj 2.625 0 Td 44.074074 Tz (vials ) Tj 1.575 0 Td 52.662037 Tz (with ) Tj 1.497222 0 Td 58.333333 Tz (a ) Tj 0.563889 0 Td 48.611111 Tz (pipet ) Tj 1.711111 0 Td 58.333333 Tz (and ) Tj 1.302778 0 Td 58.333333 Tz (were ) Tj 1.594444 0 Td 53.472222 Tz (placed ) Tj 2.158333 0 Td 46.990741 Tz (into ) Tj 1.361111 0 Td 51.527778 Tz (disposable ) Tj 52.857143 0 0 52.857143 0 1619.915663 Tm 6.186486 0 Td 48.085586 Tz (cuvettes ) Tj 2.440541 0 Td 51.801802 Tz (without ) Tj 2.308108 0 Td 45.326577 Tz (dilution ) Tj 2.327027 0 Td 52.552553 Tz (\(70 ) Tj 1.135135 0 Td 49.399399 Tz (uL, ) Tj 1.021622 0 Td 49.399399 Tz (8.5 ) Tj 1.059459 0 Td 88.288288 Tz (mm ) Tj 1.210811 0 Td 48.873874 Tz (center ) Tj 1.835135 0 Td 49.924925 Tz (height ) Tj 1.986486 0 Td 56.756757 Tz (Brand ) Tj 51.428571 0 0 51.428571 0 1578 Tm 6.358333 0 Td 58.009259 Tz (UV-Cuvette ) Tj 3.752778 0 Td 49.537037 Tz (micro\). ) Tj 2.333333 0 Td 61.574074 Tz (At ) Tj 0.991667 0 Td 44.722222 Tz (least ) Tj 1.672222 0 Td 53.472222 Tz (10 ) Tj 0.913889 0 Td 51.851852 Tz (scans ) Tj 1.827778 0 Td 59.143519 Tz (were ) Tj 1.672222 0 Td 48.611111 Tz (collected ) Tj 2.897222 0 Td 59.143519 Tz (from ) Tj 51.428571 0 0 51.428571 0 1541.010989 Tm 6.358333 0 Td 55.092593 Tz (each ) Tj 1.516667 0 Td 52.777778 Tz (sample. ) Tj 51.428571 0 0 51.428571 0 1498.926829 Tm 6.338889 0 Td 68.055556 Tz (UV/VIS ) Tj 2.625 0 Td 54.552469 Tz (Spectroscopy ) Tj 51.428571 0 0 51.428571 0 1457.260536 Tm 7.097222 0 Td 85.87963 Tz (UV ) Tj 1.263889 0 Td 48.611111 Tz (spectra ) Tj 2.275 0 Td 58.333333 Tz (were ) Tj 1.633333 0 Td 52.662037 Tz (recorded ) Tj 2.741667 0 Td 59.953704 Tz (on ) Tj 0.894444 0 Td 52.314815 Tz (Agilent ) Tj 2.372222 0 Td 53.742284 Tz (Technologies ) Tj 4.083333 0 Td 59.953704 Tz (8453 ) Tj 51.428571 0 0 51.428571 0 1415.324582 Tm 6.358333 0 Td 85.87963 Tz (UV ) Tj 1.186111 0 Td 53.376906 Tz (spectrophotometer ) Tj 5.541667 0 Td 45.37037 Tz (in ) Tj 0.719444 0 Td 49.691358 Tz (quartz ) Tj 1.925 0 Td 49.537037 Tz (cuvette ) Tj 2.236111 0 Td 43.75 Tz (in ) Tj 0.680556 0 Td 49.691358 Tz (the ) Tj 1.05 0 Td 52.5 Tz (range ) Tj 1.730556 0 Td 57.407407 Tz (200-700 ) Tj 51.428571 0 0 51.428571 0 1372.606965 Tm 6.358333 0 Td 60.493827 Tz (nm. ) Tj 1.438889 0 Td 60.277778 Tz (Molar ) Tj 2.080556 0 Td 48.287037 Tz (extinction ) Tj 3.208333 0 Td 46.254209 Tz (coefficient ) Tj 3.344444 0 Td 45.37037 Tz (\(e\) ) Tj 1.127778 0 Td 48.611111 Tz (for ) Tj 1.166667 0 Td 53.06713 Tz (2,2-dimethoxy-2- ) Tj 51.428571 0 0 51.428571 0 1331.498575 Tm 6.358333 0 Td 55.272634 Tz (phenylacetophenone ) Tj 6.727778 0 Td 45.37037 Tz (in ) Tj 1.302778 0 Td 83.449074 Tz (MeCH ) Tj 2.8 0 Td 60.493827 Tz (was ) Tj 1.866667 0 Td 54.444444 Tz (determined ) Tj 4.005556 0 Td 43.209877 Tz (\(at ) Tj 57.142857 0 0 57.142857 0 1287 Tm 5.985 0 Td 60.833333 Tz (max=253 ) Tj 2.73 0 Td 59.305556 Tz (nm\) ) Tj 1.2425 0 Td 39.375 Tz (to ) Tj 0.63 0 Td 52.5 Tz (be ) Tj 0.84 0 Td 54.444444 Tz (12200+100 ) Tj 3.115 0 Td 58.333333 Tz (L ) Tj 0.5425 0 Td 61.979167 Tz (mol' ) Tj 1.6975 0 Td 81.666667 Tz (cm. ) Tj 30 0 0 30 0 1923 Tm 41.6 0 Td 77.777778 Tz (25 ) Tj 30 0 0 30 0 1716 Tm 41.6 0 Td 80.555556 Tz (30 ) Tj 30 0 0 30 0 1507 Tm 41.6 0 Td 77.777778 Tz (35 ) Tj 30 0 0 30 0 1299 Tm 41.566667 0 Td 83.333333 Tz (40 ) Tj 51.428571 0 0 51.428571 0 1215.333333 Tm 13.552778 0 Td 61.111111 Tz (Example ) Tj 2.8 0 Td 38.888889 Tz (1 ) Tj 51.428571 0 0 51.428571 0 1130.166466 Tm 6.377778 0 Td 51.131687 Tz (Synthesis ) Tj 2.975 0 Td 58.333333 Tz (of ) Tj 0.855556 0 Td 55.632716 Tz (Nanocapsules ) Tj 4.258333 0 Td 51.851852 Tz (with ) Tj 1.516667 0 Td 54.73251 Tz (Entrapped ) Tj 3.169444 0 Td 48.611111 Tz (Silver ) Tj 1.963889 0 Td 64.351852 Tz (Nanopar ) Tj 40 0 0 40 0 1091 Tm 8.15 0 Td 55.555556 Tz (ticles ) Tj 51.428571 0 0 51.428571 0 1046.720207 Tm 7.097222 0 Td 55.902778 Tz (Nanocapsules ) Tj 4.355556 0 Td 52.662037 Tz (with ) Tj 1.613889 0 Td 53.292181 Tz (entrapped ) Tj 3.227778 0 Td 44.830247 Tz (silver ) Tj 1.944444 0 Td 49.109687 Tz (nanoparticles ) Tj 4.2 0 Td 58.333333 Tz (were ) Tj 51.428571 0 0 51.428571 0 1007.090465 Tm 6.358333 0 Td 53.06713 Tz (prepared ) Tj 2.780556 0 Td 59.953704 Tz (by ) Tj 1.011111 0 Td 47.530864 Tz (the ) Tj 1.127778 0 Td 51.851852 Tz (following ) Tj 3.033333 0 Td 51.527778 Tz (procedure: ) Tj 3.363889 0 Td 48.420479 Tz (tert-Butylstyrene ) Tj 5.191667 0 Td 52.932099 Tz (\(24 ) Tj 58.571429 0 0 58.571429 0 961.214286 Tm 5.617073 0 Td 45.528455 Tz (uL, ) Tj 1.178049 0 Td 49.593496 Tz (1.33x10 ) Tj 2.868293 0 Td 44.390244 Tz (mol\), ) Tj 1.639024 0 Td 46.239837 Tz (p-divinylbenzene ) Tj 4.695122 0 Td 47.425474 Tz (\(19 ) Tj 1.195122 0 Td 44.579946 Tz (ul, ) Tj 1.160976 0 Td 50 Tz (1.33x10 ) Tj 51.428571 0 0 51.428571 0 922.595152 Tm 6.358333 0 Td 51.851852 Tz (mol\), ) Tj 2.002778 0 Td 60.493827 Tz (and ) Tj 1.536111 0 Td 53.425926 Tz (2,2-dimethoxy-2-phenylacetophenone, ) Tj 11.725 0 Td 72.592593 Tz (DMPA, ) Tj 58.571429 0 0 58.571429 0 875.640449 Tm 5.6 0 Td 62.601626 Tz (\(UV ) Tj 1.297561 0 Td 35.853659 Tz (initiator, ) Tj 2.339024 0 Td 45.528455 Tz (0.33 ) Tj 1.263415 0 Td 54.065041 Tz (mg, ) Tj 1.195122 0 Td 53.252033 Tz (1.3x10" ) Tj 2.407317 0 Td 50.50813 Tz (mol\) ) Tj 1.34878 0 Td 52.642276 Tz (were ) Tj 1.4 0 Td 51.788618 Tz (added ) Tj 1.690244 0 Td 41.260163 Tz (to ) Tj 0.665854 0 Td 48.373984 Tz (a ) Tj 0.426829 0 Td 53.353659 Tz (solu ) Tj 58.571429 0 0 58.571429 0 833.621079 Tm 5.565854 0 Td 42.682927 Tz (tion ) Tj 1.143902 0 Td 49.796748 Tz (of ) Tj 0.665854 0 Td 75.406504 Tz (DMPC ) Tj 1.946341 0 Td 47.425474 Tz (\(60 ) Tj 0.990244 0 Td 52.168022 Tz (mg, ) Tj 1.07561 0 Td 51.219512 Tz (8.85x10 ) Tj 2.765854 0 Td 49.796748 Tz (mol\) ) Tj 1.331707 0 Td 41.260163 Tz (in ) Tj 0.631707 0 Td 62.601626 Tz (CHC1. ) Tj 1.997561 0 Td 55.96206 Tz (The ) Tj 1.143902 0 Td 69.004065 Tz (mono ) Tj 51.428571 0 0 51.428571 0 793.94155 Tm 6.358333 0 Td 58.333333 Tz (mers ) Tj 1.652778 0 Td 58.333333 Tz (were ) Tj 1.613889 0 Td 47.395833 Tz (purified ) Tj 2.508333 0 Td 56.712963 Tz (on ) Tj 0.894444 0 Td 58.333333 Tz (a ) Tj 0.563889 0 Td 60.493827 Tz (column ) Tj 2.411111 0 Td 56.712963 Tz (of ) Tj 0.855556 0 Td 47.222222 Tz (neutral ) Tj 2.197222 0 Td 56.018519 Tz (alumina ) Tj 2.566667 0 Td 47.962963 Tz (prior ) Tj 1.633333 0 Td 46.990741 Tz (to ) Tj 51.428571 0 0 51.428571 0 753.15212 Tm 6.358333 0 Td 47.170782 Tz (addition. ) Tj 2.741667 0 Td 62.654321 Tz (The ) Tj 1.322222 0 Td 73.726852 Tz (CHCl ) Tj 2.158333 0 Td 61.574074 Tz (was ) Tj 1.283333 0 Td 53.148148 Tz (evaporated ) Tj 3.383333 0 Td 51.851852 Tz (using ) Tj 1.75 0 Td 55.092593 Tz (a ) Tj 0.525 0 Td 52.391975 Tz (stream ) Tj 2.119444 0 Td 56.712963 Tz (of ) Tj 0.777778 0 Td 58.333333 Tz (puri ) Tj 51.428571 0 0 51.428571 0 712.359354 Tm 6.358333 0 Td 46.180556 Tz (fied ) Tj 1.361111 0 Td 55.092593 Tz (argon ) Tj 1.944444 0 Td 45.37037 Tz (to ) Tj 0.855556 0 Td 57.523148 Tz (form ) Tj 1.672222 0 Td 55.092593 Tz (a ) Tj 0.622222 0 Td 56.588319 Tz (lipid-monomer ) Tj 4.666667 0 Td 46.990741 Tz (film ) Tj 1.419444 0 Td 59.953704 Tz (on ) Tj 1.011111 0 Td 49.691358 Tz (the ) Tj 1.186111 0 Td 51.041667 Tz (wall ) Tj 1.516667 0 Td 59.953704 Tz (of ) Tj 0.894444 0 Td 55.092593 Tz (a ) Tj 40 0 0 40 0 675 Tm 8.175 0 Td 61.904762 Tz (culture ) Tj 2.825 0 Td 60 Tz (tube. ) Tj 2 0 Td 81.944444 Tz (The ) Tj 1.7 0 Td 60.416667 Tz (film ) Tj 1.725 0 Td 77.777778 Tz (was ) Tj 1.625 0 Td 61.309524 Tz (further ) Tj 2.75 0 Td 64.166667 Tz (dried ) Tj 2.125 0 Td 72.5 Tz (under ) Tj 2.35 0 Td 80.555556 Tz (vacuum ) Tj 3.125 0 Td 62.5 Tz (for ) Tj 1.275 0 Td 81.25 Tz (30 ) Tj 52.857143 0 0 52.857143 0 626.286236 Tm 6.186486 0 Td 59.90991 Tz (minto ) Tj 1.986486 0 Td 58.333333 Tz (remove ) Tj 2.27027 0 Td 45.720721 Tz (traces ) Tj 1.816216 0 Td 53.603604 Tz (of ) Tj 0.737838 0 Td 69.369369 Tz (CHC1. ) Tj 2.27027 0 Td 60.960961 Tz (The ) Tj 1.267568 0 Td 48.558559 Tz (dried ) Tj 1.608108 0 Td 46.509009 Tz (film ) Tj 1.286486 0 Td 60.960961 Tz (was ) Tj 1.286486 0 Td 52.027027 Tz (hydrated ) Tj 58.571429 0 0 58.571429 0 585.988636 Tm 5.565854 0 Td 47.662602 Tz (with ) Tj 1.314634 0 Td 51.219512 Tz (10 ) Tj 1.246341 0 Td 54.065041 Tz (mol ) Tj 1.092683 0 Td 43.038618 Tz (solution ) Tj 2.202439 0 Td 45.528455 Tz (of ) Tj 0.614634 0 Td 63.170732 Tz (AgNO, ) Tj 2.065854 0 Td 39.837398 Tz (in ) Tj 0.597561 0 Td 46.160795 Tz (deionized ) Tj 2.595122 0 Td 48.373984 Tz (water ) Tj 1.553659 0 Td 38.414634 Tz (to ) Tj 0.580488 0 Td 45.528455 Tz (give ) Tj 1.195122 0 Td 51.219512 Tz (a ) Tj 51.428571 0 0 51.428571 0 543.426573 Tm 6.358333 0 Td 49.583333 Tz (dispersion ) Tj 3.111111 0 Td 55.092593 Tz (of ) Tj 0.738889 0 Td 50.356125 Tz (multilamellar ) Tj 4.025 0 Td 45.37037 Tz (vesicles, ) Tj 2.586111 0 Td 58.981481 Tz (which ) Tj 1.866667 0 Td 61.574074 Tz (was ) Tj 1.244444 0 Td 51.041667 Tz (then ) Tj 1.361111 0 Td 53.472222 Tz (extruded ) Tj 51.428571 0 0 51.428571 0 506.142125 Tm 6.358333 0 Td 45.37037 Tz (at ) Tj 0.855556 0 Td 55.092593 Tz (35 ) Tj 1.302778 0 Td 55.092593 Tz (C. ) Tj 1.030556 0 Td 53.240741 Tz (through ) Tj 2.566667 0 Td 51.851852 Tz (a ) Tj 0.641667 0 Td 52.849003 Tz (polycarbonate ) Tj 4.452778 0 Td 56.712963 Tz (Nucleopore ) Tj 3.733333 0 Td 48.611111 Tz (track-etch ) Tj 51.428571 0 0 51.428571 0 461.376738 Tm 6.358333 0 Td 64.00463 Tz (membrane ) Tj 3.325 0 Td 61.213992 Tz (\(Whatman\) ) Tj 3.597222 0 Td 52.662037 Tz (with ) Tj 1.555556 0 Td 55.740741 Tz (0.1-m ) Tj 1.925 0 Td 55.092593 Tz (pore ) Tj 1.575 0 Td 47.800926 Tz (size ) Tj 1.380556 0 Td 53.148148 Tz (using ) Tj 1.827778 0 Td 58.333333 Tz (a ) Tj 0.641667 0 Td 55.092593 Tz (Lipex ) Tj 51.428571 0 0 51.428571 0 420.44878 Tm 6.377778 0 Td 45.010288 Tz (stainless ) Tj 2.644444 0 Td 44.722222 Tz (steel ) Tj 1.536111 0 Td 51.041667 Tz (extruder ) Tj 2.644444 0 Td 52.572016 Tz (\(Northern ) Tj 3.072222 0 Td 46.585648 Tz (Lipids\). ) Tj 2.508333 0 Td 47.962963 Tz (Prior ) Tj 1.613889 0 Td 46.990741 Tz (to ) Tj 0.777778 0 Td 62.962963 Tz (polymer ) Tj 48.571429 0 0 48.571429 0 378 Tm 6.732353 0 Td 47.610294 Tz (ization, ) Tj 2.491176 0 Td 58.333333 Tz (unloaded ) Tj 2.985294 0 Td 47.46732 Tz (silver ) Tj 1.852941 0 Td 53.186275 Tz (ions ) Tj 1.482353 0 Td 61.764706 Tz (were ) Tj 1.647059 0 Td 63.235294 Tz (removed ) Tj 2.861765 0 Td 60.906863 Tz (from ) Tj 1.688235 0 Td 51.470588 Tz (the ) Tj 1.132353 0 Td 56.372549 Tz (mixture ) Tj 51.428571 0 0 51.428571 0 339.206388 Tm 6.338889 0 Td 61.574074 Tz (by ) Tj 1.030556 0 Td 49.305556 Tz (size-exclusion ) Tj 4.413889 0 Td 56.712963 Tz (chromatography ) Tj 5.036111 0 Td 59.953704 Tz (on ) Tj 1.011111 0 Td 58.738426 Tz (Sephadex ) Tj 3.091667 0 Td 63.194444 Tz (G-50 ) Tj 1.769444 0 Td 62.654321 Tz (col ) Tj 51.428571 0 0 51.428571 0 298.531915 Tm 6.338889 0 Td 61.574074 Tz (umn. ) Tj 1.613889 0 Td 63.734568 Tz (Oxygen ) Tj 2.45 0 Td 60.493827 Tz (was ) Tj 1.244444 0 Td 59.722222 Tz (removed ) Tj 2.625 0 Td 58.333333 Tz (by ) Tj 0.836111 0 Td 52.314815 Tz (passing ) Tj 2.313889 0 Td 46.990741 Tz (purified ) Tj 2.372222 0 Td 54.444444 Tz (argon ) Tj 1.75 0 Td 54.62963 Tz (through ) Tj 51.428571 0 0 51.428571 0 252.136786 Tm 6.338889 0 Td 50.771605 Tz (the ) Tj 1.225 0 Td 46.090535 Tz (solution. ) Tj 2.819444 0 Td 62.654321 Tz (The ) Tj 1.419444 0 Td 57.79321 Tz (sample ) Tj 2.372222 0 Td 61.574074 Tz (was ) Tj 1.438889 0 Td 46.342593 Tz (irradiated ) Tj 3.111111 0 Td 70 Tz (\(v254 ) Tj 2.45 0 Td 64.814815 Tz (nm\) ) Tj 1.458333 0 Td 45.37037 Tz (in ) Tj 0.875 0 Td 55.092593 Tz (a ) Tj 51.428571 0 0 51.428571 0 214.232503 Tm 6.358333 0 Td 54.843305 Tz (photochemical ) Tj 4.452778 0 Td 47.685185 Tz (reactor ) Tj 2.1 0 Td 55.497685 Tz (equipped ) Tj 2.8 0 Td 52.662037 Tz (with ) Tj 1.380556 0 Td 55.092593 Tz (a ) Tj 0.466667 0 Td 42.12963 Tz (stirrer ) Tj 1.866667 0 Td 54.012346 Tz (\(10 ) Tj 1.088889 0 Td 57.685185 Tz (lamps ) Tj 1.847222 0 Td 55.092593 Tz (of ) Tj 0.738889 0 Td 59.953704 Tz (32 ) Tj 51.428571 0 0 51.428571 0 170.07 Tm 6.358333 0 Td 106.944444 Tz (W ) Tj 0.875 0 Td 50.555556 Tz (each; ) Tj 1.788889 0 Td 58.981481 Tz (10-cm ) Tj 2.002778 0 Td 49.421296 Tz (distance ) Tj 2.547222 0 Td 57.87037 Tz (between ) Tj 2.644444 0 Td 48.611111 Tz (the ) Tj 1.05 0 Td 57.685185 Tz (lamps ) Tj 1.944444 0 Td 58.333333 Tz (and ) Tj 1.225 0 Td 48.611111 Tz (the ) Tj 1.088889 0 Td 54.62963 Tz (sample\) ) Tj 30 0 0 30 0 1091 Tm 41.566667 0 Td 80.555556 Tz (45 ) Tj 30 0 0 30 0 883 Tm 41.6 0 Td 80.555556 Tz (50 ) Tj 30 0 0 30 0 675 Tm 41.6 0 Td 77.777778 Tz (55 ) Tj 30 0 0 30 0 467 Tm 41.633333 0 Td 77.777778 Tz (60 ) Tj 30 0 0 30 0 259 Tm 41.633333 0 Td 75 Tz (65 ) Tj 52.857143 0 0 52.857143 0 2968 Tm 32.881081 0 Td 72.522523 Tz (8 ) Tj 51.428571 0 0 51.428571 0 2914.55122 Tm 25.297222 0 Td 49.691358 Tz (for ) Tj 1.030556 0 Td 59.953704 Tz (60 ) Tj 0.894444 0 Td 51.851852 Tz (min. ) Tj 1.438889 0 Td 57.523148 Tz (Methanol ) Tj 2.916667 0 Td 55.092593 Tz (\(10 ) Tj 1.147222 0 Td 69.135802 Tz (mL\) ) Tj 1.380556 0 Td 61.574074 Tz (was ) Tj 1.244444 0 Td 54.012346 Tz (added, ) Tj 2.080556 0 Td 59.41358 Tz (and ) Tj 1.244444 0 Td 48.611111 Tz (the ) Tj 0.991667 0 Td 46.843434 Tz (precipitate ) Tj 40 0 0 40 0 2880 Tm 32.5 0 Td 80.555556 Tz (was ) Tj 1.65 0 Td 77.083333 Tz (washed ) Tj 2.875 0 Td 69.444444 Tz (3-5 ) Tj 1.425 0 Td 66.666667 Tz (times ) Tj 2.2 0 Td 68.75 Tz (with ) Tj 1.8 0 Td 67.592593 Tz (methanol. ) Tj 3.85 0 Td 72.222222 Tz (For ) Tj 1.45 0 Td 95.833333 Tz (DLS ) Tj 1.925 0 Td 73.611111 Tz (measurements ) Tj 51.428571 0 0 51.428571 0 2835.845387 Tm 25.297222 0 Td 58.333333 Tz (and ) Tj 1.438889 0 Td 55.308642 Tz (UV-spectroscopy ) Tj 5.327778 0 Td 53.877315 Tz (prepared ) Tj 2.975 0 Td 53.20216 Tz (nanocapsules ) Tj 4.219444 0 Td 59.143519 Tz (were ) Tj 1.769444 0 Td 57.685185 Tz (resus ) Tj 51.428571 0 0 51.428571 0 2789.507097 Tm 25.297222 0 Td 58.333333 Tz (pended ) Tj 2.333333 0 Td 46.990741 Tz (in ) Tj 0.777778 0 Td 49.691358 Tz (Triton ) Tj 2.041667 0 Td 62.222222 Tz (X-100 ) Tj 2.1 0 Td 48.611111 Tz (solution ) Tj 2.586111 0 Td 45.37037 Tz (in ) Tj 0.816667 0 Td 53.148148 Tz (water ) Tj 1.808333 0 Td 47.800926 Tz (\(0.5 ) Tj 1.419444 0 Td 64.814815 Tz (mL, ) Tj 1.4 0 Td 68.055556 Tz (2%\) ) Tj 1.438889 0 Td 61.574074 Tz (by ) Tj 51.428571 0 0 51.428571 0 2751.523077 Tm 25.316667 0 Td 43.344907 Tz (stirring ) Tj 2.255556 0 Td 49.691358 Tz (for ) Tj 1.088889 0 Td 38.888889 Tz (1 ) Tj 0.466667 0 Td 61.574074 Tz (h ) Tj 0.563889 0 Td 45.37037 Tz (at ) Tj 0.719444 0 Td 56.018519 Tz (ambient ) Tj 2.508333 0 Td 50.501543 Tz (temperature. ) Tj 51.428571 0 0 51.428571 0 2708.082294 Tm 26.016667 0 Td 66.435185 Tz (As ) Tj 0.972222 0 Td 51.851852 Tz (described ) Tj 2.936111 0 Td 52.932099 Tz (above, ) Tj 2.080556 0 Td 54.372428 Tz (liposomes ) Tj 3.111111 0 Td 51.203704 Tz (containing ) Tj 3.286111 0 Td 62.789352 Tz (monomers ) Tj 3.208333 0 Td 44.560185 Tz (\(1:1 ) Tj 51.428571 0 0 51.428571 0 2669.311005 Tm 25.297222 0 Td 54.166667 Tz (mixture ) Tj 2.45 0 Td 59.953704 Tz (of ) Tj 0.816667 0 Td 47.086057 Tz (tert-butylstyrene ) Tj 4.997222 0 Td 58.333333 Tz (and ) Tj 1.263889 0 Td 51.635802 Tz (divinylbenzene\) ) Tj 4.822222 0 Td 60.493827 Tz (and ) Tj 1.244444 0 Td 55.092593 Tz (a ) Tj 0.525 0 Td 74.537037 Tz (pho ) Tj 51.428571 0 0 51.428571 0 2627.523364 Tm 25.277778 0 Td 44.191919 Tz (toinitiator ) Tj 3.286111 0 Td 53.20216 Tz (\(2,2-dimethoxy-2-phenylacetophenone, ) Tj 11.958333 0 Td 74.537037 Tz (DMPA\) ) Tj 51.428571 0 0 51.428571 0 2584.518834 Tm 25.297222 0 Td 45.37037 Tz (in ) Tj 0.7 0 Td 50.771605 Tz (the ) Tj 1.030556 0 Td 49.074074 Tz (bilayer ) Tj 2.158333 0 Td 59.41358 Tz (and ) Tj 1.225 0 Td 45.37037 Tz (silver ) Tj 1.769444 0 Td 48.611111 Tz (ions ) Tj 1.341667 0 Td 45.37037 Tz (in ) Tj 0.680556 0 Td 50.771605 Tz (the ) Tj 1.030556 0 Td 56.944444 Tz (aqueous ) Tj 2.547222 0 Td 52.662037 Tz (core ) Tj 1.380556 0 Td 50.771605 Tz (are ) Tj 1.030556 0 Td 53.877315 Tz (prepared ) Tj 51.428571 0 0 51.428571 0 2541.794157 Tm 25.277778 0 Td 61.574074 Tz (by ) Tj 1.069444 0 Td 51.49177 Tz (hydrating ) Tj 3.072222 0 Td 58.333333 Tz (a ) Tj 0.7 0 Td 53.240741 Tz (mixture ) Tj 2.547222 0 Td 56.712963 Tz (of ) Tj 0.913889 0 Td 44.290123 Tz (lipids ) Tj 1.905556 0 Td 60.493827 Tz (and ) Tj 1.419444 0 Td 63.194444 Tz (monomers ) Tj 3.383333 0 Td 51.851852 Tz (with ) Tj 1.575 0 Td 49.691358 Tz (the ) Tj 51.428571 0 0 51.428571 0 2498.52657 Tm 25.297222 0 Td 56.481481 Tz (aqueous ) Tj 2.566667 0 Td 48.206019 Tz (solution ) Tj 2.488889 0 Td 59.953704 Tz (of ) Tj 0.816667 0 Td 44.830247 Tz (silver ) Tj 1.788889 0 Td 43.518519 Tz (nitrate ) Tj 2.022222 0 Td 53.06713 Tz (followed ) Tj 2.722222 0 Td 58.333333 Tz (by ) Tj 0.875 0 Td 47.638889 Tz (extrusion. ) Tj 3.052778 0 Td 63.734568 Tz (The ) Tj 51.428571 0 0 51.428571 0 2457.810143 Tm 25.316667 0 Td 56.712963 Tz (sample ) Tj 2.294444 0 Td 38.888889 Tz (is ) Tj 0.738889 0 Td 51.041667 Tz (then ) Tj 1.477778 0 Td 46.666667 Tz (irradiated ) Tj 3.033333 0 Td 53.472222 Tz (with ) Tj 1.555556 0 Td 84.259259 Tz (UV ) Tj 1.263889 0 Td 44.722222 Tz (light ) Tj 1.594444 0 Td 45.37037 Tz (to ) Tj 0.797222 0 Td 42.12963 Tz (initiate ) Tj 2.236111 0 Td 54.282407 Tz (both ) Tj 1.555556 0 Td 50.771605 Tz (the ) Tj 51.428571 0 0 51.428571 0 2418.163462 Tm 25.297222 0 Td 52.314815 Tz (polymerization ) Tj 4.608333 0 Td 60.493827 Tz (and ) Tj 1.302778 0 Td 52.932099 Tz (formation ) Tj 3.111111 0 Td 56.712963 Tz (of ) Tj 0.836111 0 Td 47.916667 Tz (nanoparticles. ) Tj 4.238889 0 Td 64.814815 Tz (The ) Tj 1.4 0 Td 65.462963 Tz (forma ) Tj 51.428571 0 0 51.428571 0 2376.353584 Tm 25.277778 0 Td 46.990741 Tz (tion ) Tj 1.302778 0 Td 58.333333 Tz (of ) Tj 0.777778 0 Td 48.611111 Tz (nano-particles ) Tj 4.238889 0 Td 40.509259 Tz (is ) Tj 0.622222 0 Td 55.092593 Tz (evidenced ) Tj 3.111111 0 Td 58.333333 Tz (by ) Tj 0.894444 0 Td 48.611111 Tz (the ) Tj 1.011111 0 Td 53.472222 Tz (yellow ) Tj 2.1 0 Td 51.203704 Tz (color ) Tj 1.672222 0 Td 58.333333 Tz (due ) Tj 1.186111 0 Td 45.37037 Tz (to ) Tj 51.428571 0 0 51.428571 0 2335.819876 Tm 25.316667 0 Td 49.537037 Tz (Surface ) Tj 2.411111 0 Td 58.796296 Tz (plasmon ) Tj 2.8 0 Td 50.87963 Tz (resonance. ) Tj 3.480556 0 Td 52.314815 Tz (Polymerization ) Tj 4.763889 0 Td 60.493827 Tz (was ) Tj 1.419444 0 Td 47.530864 Tz (typically ) Tj 51.428571 0 0 51.428571 0 2293.544794 Tm 25.297222 0 Td 55.902778 Tz (complete ) Tj 2.819444 0 Td 51.311728 Tz (within ) Tj 2.041667 0 Td 57.253086 Tz (one ) Tj 1.166667 0 Td 49.259259 Tz (hour. ) Tj 1.633333 0 Td 62.654321 Tz (The ) Tj 1.322222 0 Td 44.560185 Tz (rate ) Tj 1.225 0 Td 55.092593 Tz (of ) Tj 0.738889 0 Td 52.777778 Tz (polymerization ) Tj 4.608333 0 Td 37.268519 Tz (is ) Tj 0.622222 0 Td 71.296296 Tz (con ) Tj 51.428571 0 0 51.428571 0 2252.088235 Tm 25.316667 0 Td 43.981481 Tz (sistent ) Tj 2.061111 0 Td 53.472222 Tz (with ) Tj 1.516667 0 Td 51.851852 Tz (previous ) Tj 2.702778 0 Td 47.222222 Tz (kinetic ) Tj 2.255556 0 Td 47.222222 Tz (studies ) Tj 2.255556 0 Td 55.092593 Tz (of ) Tj 0.836111 0 Td 49.537037 Tz (styrene ) Tj 2.275 0 Td 58.981481 Tz (polymeriza ) Tj 58.571429 0 0 58.571429 0 2208.282767 Tm 22.195122 0 Td 41.971545 Tz (tion ) Tj 1.195122 0 Td 39.837398 Tz (in ) Tj 0.64878 0 Td 47.615176 Tz (micro-emulsions ) Tj 4.439024 0 Td 51.219512 Tz (and ) Tj 1.07561 0 Td 45.325203 Tz (self-assembled ) Tj 3.978049 0 Td 49.559621 Tz (monolayers." ) Tj 51.428571 0 0 51.428571 0 2168.647355 Tm 26.036111 0 Td 48.611111 Tz (In ) Tj 0.758333 0 Td 51.203704 Tz (these ) Tj 1.730556 0 Td 56.17284 Tz (Examples, ) Tj 3.208333 0 Td 50.771605 Tz (the ) Tj 1.069444 0 Td 44.074074 Tz (total ) Tj 1.497222 0 Td 61.574074 Tz (amount ) Tj 2.391667 0 Td 58.333333 Tz (of ) Tj 0.777778 0 Td 47.685185 Tz (photoinitiator ) Tj 4.161111 0 Td 62.654321 Tz (was ) Tj 51.428571 0 0 51.428571 0 2126.012865 Tm 25.297222 0 Td 53.596866 Tz (approximately ) Tj 4.375 0 Td 46.450617 Tz (1.5 ) Tj 0.952778 0 Td 52.5 Tz (times ) Tj 1.672222 0 Td 49.537037 Tz (greater ) Tj 2.138889 0 Td 53.472222 Tz (than ) Tj 1.380556 0 Td 49.691358 Tz (the ) Tj 0.972222 0 Td 61.574074 Tz (amount ) Tj 2.333333 0 Td 53.472222 Tz (of ) Tj 0.719444 0 Td 48.611111 Tz (silverions ) Tj 51.428571 0 0 51.428571 0 2085.971631 Tm 25.297222 0 Td 53.292181 Tz (entrapped ) Tj 3.072222 0 Td 51.311728 Tz (within ) Tj 2.061111 0 Td 51.851852 Tz (liposomes. ) Tj 3.325 0 Td 63.734568 Tz (The ) Tj 1.341667 0 Td 45.37037 Tz (starting ) Tj 2.411111 0 Td 55.092593 Tz (monomerinitiator ) Tj 40 0 0 40 0 2048 Tm 32.525 0 Td 56.666667 Tz (ratio ) Tj 1.95 0 Td 79.166667 Tz (was ) Tj 1.65 0 Td 65.277778 Tz (200:1. ) Tj 51.428571 0 0 51.428571 0 2001.659631 Tm 26.016667 0 Td 52.5 Tz (After ) Tj 1.788889 0 Td 48.611111 Tz (the ) Tj 1.088889 0 Td 47.314815 Tz (synthesis, ) Tj 3.052778 0 Td 49.691358 Tz (the ) Tj 1.108333 0 Td 44.722222 Tz (lipid ) Tj 1.575 0 Td 48.206019 Tz (scaffold ) Tj 2.527778 0 Td 55.092593 Tz (can ) Tj 1.225 0 Td 58.333333 Tz (be ) Tj 0.952778 0 Td 59.259259 Tz (removed ) Tj 2.702778 0 Td 59.953704 Tz (by ) Tj 51.428571 0 0 51.428571 0 1961.26601 Tm 25.297222 0 Td 46.990741 Tz (either ) Tj 1.866667 0 Td 47.115385 Tz (precipitation ) Tj 3.888889 0 Td 59.41358 Tz (and ) Tj 1.283333 0 Td 57.87037 Tz (washing ) Tj 2.644444 0 Td 53.472222 Tz (with ) Tj 1.516667 0 Td 55.902778 Tz (methanol ) Tj 2.916667 0 Td 53.472222 Tz (or ) Tj 0.797222 0 Td 61.574074 Tz (by ) Tj 0.972222 0 Td 52.5 Tz (using ) Tj 51.428571 0 0 51.428571 0 1916.141451 Tm 25.316667 0 Td 45.910494 Tz (surfactants, ) Tj 3.519444 0 Td 54.282407 Tz (such ) Tj 1.497222 0 Td 50.231481 Tz (as ) Tj 0.797222 0 Td 49.691358 Tz (Triton ) Tj 2.002778 0 Td 62.87037 Tz (X-100 ) Tj 2.061111 0 Td 53.472222 Tz (or ) Tj 0.816667 0 Td 58.333333 Tz (sodium ) Tj 2.352778 0 Td 53.703704 Tz (dodecyl ) Tj 2.488889 0 Td 45.833333 Tz (sulfate ) Tj 51.428571 0 0 51.428571 0 1874 Tm 25.316667 0 Td 54.012346 Tz (\(SDS\). ) Tj 51.428571 0 0 51.428571 0 1833.955774 Tm 26.016667 0 Td 72.106481 Tz (When ) Tj 1.905556 0 Td 47.138047 Tz (Surfactants ) Tj 3.227778 0 Td 50.771605 Tz (are ) Tj 1.05 0 Td 49.907407 Tz (used, ) Tj 1.652778 0 Td 53.742284 Tz (nanocapsules ) Tj 4.005556 0 Td 50.771605 Tz (are ) Tj 1.011111 0 Td 48.611111 Tz (solubilized ) Tj 3.325 0 Td 48.611111 Tz (in ) Tj 51.428571 0 0 51.428571 0 1793.44504 Tm 25.277778 0 Td 48.611111 Tz (water. ) Tj 2.197222 0 Td 47.364672 Tz (Precipitation ) Tj 4.122222 0 Td 57.523148 Tz (from ) Tj 1.827778 0 Td 55.902778 Tz (methanol ) Tj 3.111111 0 Td 55.092593 Tz (can ) Tj 1.419444 0 Td 58.333333 Tz (be ) Tj 1.108333 0 Td 53.472222 Tz (followed ) Tj 2.955556 0 Td 61.574074 Tz (by ) Tj 51.428571 0 0 51.428571 0 1754.33969 Tm 25.297222 0 Td 50.356125 Tz (freeze-drying ) Tj 4.102778 0 Td 58.333333 Tz (from ) Tj 1.594444 0 Td 57.407407 Tz (benzene ) Tj 2.566667 0 Td 58.333333 Tz (and ) Tj 1.283333 0 Td 53.796296 Tz (Subsequent ) Tj 3.422222 0 Td 51.851852 Tz (resuspension ) Tj 3.947222 0 Td 46.990741 Tz (in ) Tj 51.428571 0 0 51.428571 0 1710.355769 Tm 25.297222 0 Td 51.388889 Tz (organic ) Tj 2.313889 0 Td 46.8107 Tz (solvents. ) Tj 2.722222 0 Td 54.282407 Tz (Capsules ) Tj 2.780556 0 Td 54.012346 Tz (can ) Tj 1.147222 0 Td 58.333333 Tz (be ) Tj 0.875 0 Td 48.611111 Tz (freeze-dried ) Tj 3.636111 0 Td 59.41358 Tz (and ) Tj 1.205556 0 Td 49.691358 Tz (stored ) Tj 1.963889 0 Td 47.530864 Tz (for ) Tj 51.428571 0 0 51.428571 0 1670.005019 Tm 25.297222 0 Td 56.712963 Tz (an ) Tj 0.933333 0 Td 54.282407 Tz (extended ) Tj 2.877778 0 Td 51.851852 Tz (period ) Tj 2.119444 0 Td 58.333333 Tz (of ) Tj 0.836111 0 Td 55.092593 Tz (time ) Tj 1.555556 0 Td 52.391975 Tz (before ) Tj 2.138889 0 Td 52.121914 Tz (resuspension ) Tj 4.025 0 Td 45.37037 Tz (in ) Tj 0.836111 0 Td 50.925926 Tz (organic ) Tj 48.571429 0 0 48.571429 0 1631 Tm 26.805882 0 Td 51.89951 Tz (solvents ) Tj 2.676471 0 Td 58.333333 Tz (or ) Tj 0.844118 0 Td 51.470588 Tz (water. ) Tj 51.428571 0 0 51.428571 0 1588.337382 Tm 26.016667 0 Td 85.339506 Tz (TEM ) Tj 1.983333 0 Td 57.253086 Tz (images ) Tj 2.547222 0 Td 60.763889 Tz (show ) Tj 1.925 0 Td 58.796296 Tz (polymer ) Tj 2.916667 0 Td 53.20216 Tz (nanocapsules ) Tj 4.316667 0 Td 50.87963 Tz (containing ) Tj 51.428571 0 0 51.428571 0 1543.72071 Tm 25.297222 0 Td 53.796296 Tz (metal ) Tj 1.788889 0 Td 48.860399 Tz (nanoparticles ) Tj 3.986111 0 Td 55.092593 Tz (\(FIGS. ) Tj 2.158333 0 Td 55.632716 Tz (2A-C\). ) Tj 2.197222 0 Td 61.574074 Tz (Most ) Tj 1.652778 0 Td 53.20216 Tz (nanocapsules ) Tj 3.986111 0 Td 57.037037 Tz (found ) Tj 51.428571 0 0 51.428571 0 1501.257732 Tm 25.277778 0 Td 53.472222 Tz (here ) Tj 1.516667 0 Td 50.771605 Tz (are ) Tj 1.186111 0 Td 46.990741 Tz (in ) Tj 0.836111 0 Td 48.611111 Tz (the ) Tj 1.127778 0 Td 58.333333 Tz (40-120 ) Tj 2.372222 0 Td 72.916667 Tz (nm ) Tj 1.205556 0 Td 48.611111 Tz (range, ) Tj 2.002778 0 Td 48.935185 Tz (consistent ) Tj 3.188889 0 Td 53.472222 Tz (with ) Tj 1.536111 0 Td 52.256944 Tz (previous ) Tj 47.142857 0 0 47.142857 0 1465 Tm 27.618182 0 Td 49.494949 Tz (studies. ) Tj 51.428571 0 0 51.428571 0 1418.434194 Tm 26.036111 0 Td 43.308081 Tz (Statistical ) Tj 2.975 0 Td 49.016204 Tz (analysis ) Tj 2.488889 0 Td 55.092593 Tz (of ) Tj 0.738889 0 Td 84.259259 Tz (TEM ) Tj 1.652778 0 Td 51.041667 Tz (data ) Tj 1.302778 0 Td 51.388889 Tz (yielded ) Tj 2.313889 0 Td 49.691358 Tz (the ) Tj 0.991667 0 Td 54.166667 Tz (average ) Tj 2.391667 0 Td 47.800926 Tz (size ) Tj 1.244444 0 Td 59.953704 Tz (of ) Tj 51.428571 0 0 51.428571 0 1377.945205 Tm 25.316667 0 Td 44.830247 Tz (silver ) Tj 1.866667 0 Td 49.358974 Tz (nanoparticles ) Tj 4.102778 0 Td 46.990741 Tz (to ) Tj 0.816667 0 Td 58.333333 Tz (be ) Tj 0.952778 0 Td 53.240741 Tz (5.5+2.0 ) Tj 2.488889 0 Td 59.41358 Tz (nm. ) Tj 1.380556 0 Td 48.070988 Tz (Silver ) Tj 1.983333 0 Td 49.358974 Tz (nanoparticles ) Tj 51.428571 0 0 51.428571 0 1333.207729 Tm 25.277778 0 Td 59.953704 Tz (were ) Tj 1.613889 0 Td 47.222222 Tz (further ) Tj 2.119444 0 Td 49.85755 Tz (characterized ) Tj 4.044444 0 Td 59.953704 Tz (by ) Tj 0.875 0 Td 57.037037 Tz (X-ray ) Tj 1.886111 0 Td 45.959596 Tz (diffraction ) Tj 3.247222 0 Td 51.203704 Tz (\(FIG. ) Tj 1.75 0 Td 52.662037 Tz (2D\). ) Tj 1.438889 0 Td 87.5 Tz (A ) Tj 51.428571 0 0 51.428571 0 1292.835234 Tm 25.297222 0 Td 58.333333 Tz (peak ) Tj 1.516667 0 Td 46.990741 Tz (at ) Tj 0.7 0 Td 61.574074 Tz (37 ) Tj 1.186111 0 Td 37.268519 Tz (is ) Tj 0.641667 0 Td 46.064815 Tz (characteristic ) Tj 4.044444 0 Td 58.333333 Tz (of ) Tj 0.797222 0 Td 44.830247 Tz (silver ) Tj 1.75 0 Td 58.333333 Tz (and ) Tj 1.205556 0 Td 40.509259 Tz (is ) Tj 0.680556 0 Td 50.771605 Tz (not ) Tj 1.05 0 Td 50.462963 Tz (present ) Tj 2.294444 0 Td 43.75 Tz (in ) Tj 0.7 0 Td 50.771605 Tz (the ) Tj 51.428571 0 0 51.428571 0 1252.30303 Tm 25.277778 0 Td 54.444444 Tz (blank ) Tj 1.925 0 Td 53.20216 Tz (nanocapsules ) Tj 4.122222 0 Td 51.203704 Tz (\(FIG. ) Tj 1.827778 0 Td 53.472222 Tz (2D\). ) Tj 1.536111 0 Td 63.734568 Tz (The ) Tj 1.419444 0 Td 46.180556 Tz (size ) Tj 1.341667 0 Td 59.953704 Tz (of ) Tj 0.894444 0 Td 44.830247 Tz (silver ) Tj 1.886111 0 Td 60.185185 Tz (nanopar ) Tj 51.428571 0 0 51.428571 0 1211.552201 Tm 25.277778 0 Td 42.669753 Tz (ticles ) Tj 1.788889 0 Td 54.012346 Tz (has ) Tj 1.205556 0 Td 57.523148 Tz (been ) Tj 1.633333 0 Td 51.49177 Tz (estimated ) Tj 3.013889 0 Td 59.953704 Tz (by ) Tj 0.991667 0 Td 51.851852 Tz (using ) Tj 1.827778 0 Td 47.530864 Tz (the ) Tj 1.147222 0 Td 54.62963 Tz (Debye-Scherrer ) Tj 4.802778 0 Td 59.41358 Tz (for ) Tj 58.571429 0 0 58.571429 0 1168.832425 Tm 22.212195 0 Td 52.168022 Tz (mula.' ) Tj 2.270732 0 Td 56.910569 Tz (The ) Tj 1.34878 0 Td 47.560976 Tz (average ) Tj 2.321951 0 Td 40.54878 Tz (particle ) Tj 2.270732 0 Td 42.682927 Tz (size ) Tj 1.365854 0 Td 55.01355 Tz (was ) Tj 1.34878 0 Td 43.252033 Tz (calculated ) Tj 2.970732 0 Td 38.414634 Tz (to ) Tj 0.836585 0 Td 51.219512 Tz (be ) Tj 51.428571 0 0 51.428571 0 1127.610706 Tm 25.297222 0 Td 53.596866 Tz (approximately ) Tj 4.375 0 Td 58.333333 Tz (5 ) Tj 0.563889 0 Td 59.41358 Tz (nm, ) Tj 1.263889 0 Td 43.75 Tz (in ) Tj 0.7 0 Td 48.971193 Tz (excellent ) Tj 2.8 0 Td 56.17284 Tz (agreement ) Tj 3.208333 0 Td 53.472222 Tz (with ) Tj 1.438889 0 Td 85.339506 Tz (TEM ) Tj 1.730556 0 Td 45.37037 Tz (data. ) Tj 51.428571 0 0 51.428571 0 1085.062893 Tm 26.016667 0 Td 63.734568 Tz (The ) Tj 1.341667 0 Td 46.180556 Tz (role ) Tj 1.263889 0 Td 58.333333 Tz (of ) Tj 0.777778 0 Td 49.691358 Tz (the ) Tj 1.069444 0 Td 46.180556 Tz (free-radical ) Tj 3.5 0 Td 47.453704 Tz (photoinitiator ) Tj 4.161111 0 Td 43.75 Tz (in ) Tj 0.7 0 Td 48.611111 Tz (the ) Tj 1.069444 0 Td 53.652263 Tz (formation ) Tj 51.428571 0 0 51.428571 0 1048.089351 Tm 25.297222 0 Td 58.333333 Tz (of ) Tj 0.894444 0 Td 49.109687 Tz (nanoparticles ) Tj 4.122222 0 Td 61.574074 Tz (was ) Tj 1.380556 0 Td 47.800926 Tz (investigated ) Tj 3.713889 0 Td 59.953704 Tz (by ) Tj 1.011111 0 Td 51.851852 Tz (studying ) Tj 2.761111 0 Td 49.96142 Tz (nanoparticle ) Tj 51.428571 0 0 51.428571 0 1002.965435 Tm 25.277778 0 Td 52.175926 Tz (templating ) Tj 3.286111 0 Td 45.37037 Tz (in ) Tj 0.7 0 Td 54.012346 Tz (liposomes ) Tj 3.072222 0 Td 45.37037 Tz (in ) Tj 0.7 0 Td 49.691358 Tz (the ) Tj 1.030556 0 Td 54.62963 Tz (absence ) Tj 2.430556 0 Td 55.092593 Tz (of ) Tj 0.738889 0 Td 59.773663 Tz (monomers. ) Tj 3.422222 0 Td 70 Tz (Forma ) Tj 51.428571 0 0 51.428571 0 962.565901 Tm 25.277778 0 Td 46.990741 Tz (tion ) Tj 1.361111 0 Td 56.712963 Tz (of ) Tj 0.816667 0 Td 49.109687 Tz (nanoparticles ) Tj 4.025 0 Td 61.574074 Tz (was ) Tj 1.322222 0 Td 55.092593 Tz (monitored ) Tj 3.169444 0 Td 52.5 Tz (using ) Tj 1.769444 0 Td 84.259259 Tz (UV ) Tj 1.244444 0 Td 52.391975 Tz (spectroscopy ) Tj 51.428571 0 0 51.428571 0 920.152709 Tm 25.277778 0 Td 61.574074 Tz (by ) Tj 0.933333 0 Td 49.907407 Tz (increasing ) Tj 3.169444 0 Td 55.092593 Tz (absorbance ) Tj 3.461111 0 Td 46.990741 Tz (at ) Tj 0.738889 0 Td 60.493827 Tz (405 ) Tj 1.322222 0 Td 72.916667 Tz (nm ) Tj 1.108333 0 Td 58.333333 Tz (due ) Tj 1.225 0 Td 46.990741 Tz (to ) Tj 0.777778 0 Td 50.462963 Tz (Surface ) Tj 2.275 0 Td 59.259259 Tz (plasmon ) Tj 51.428571 0 0 51.428571 0 877.796117 Tm 25.297222 0 Td 54.372428 Tz (resonance ) Tj 3.072222 0 Td 51.851852 Tz (\(FIG. ) Tj 1.730556 0 Td 52.662037 Tz (3A\). ) Tj 1.458333 0 Td 51.602564 Tz (Nanoparticles ) Tj 4.2 0 Td 52.5 Tz (begin ) Tj 1.769444 0 Td 43.75 Tz (to ) Tj 0.7 0 Td 58.333333 Tz (form ) Tj 1.555556 0 Td 51.311728 Tz (within ) Tj 2.061111 0 Td 49.691358 Tz (1-2 ) Tj 51.428571 0 0 51.428571 0 834.066667 Tm 25.297222 0 Td 50.636574 Tz (minutes. ) Tj 2.625 0 Td 52.5 Tz (After ) Tj 1.711111 0 Td 48.611111 Tz (the ) Tj 1.069444 0 Td 37.592593 Tz (first ) Tj 1.341667 0 Td 58.333333 Tz (10 ) Tj 0.875 0 Td 51.041667 Tz (minutes, ) Tj 2.625 0 Td 48.611111 Tz (there ) Tj 1.633333 0 Td 61.574074 Tz (was ) Tj 1.302778 0 Td 36.728395 Tz (little ) Tj 1.458333 0 Td 58.333333 Tz (change ) Tj 2.255556 0 Td 50.231481 Tz (in ) Tj 51.428571 0 0 51.428571 0 795.76 Tm 25.277778 0 Td 50.771605 Tz (the ) Tj 1.147222 0 Td 51.203704 Tz (absorption ) Tj 3.325 0 Td 42.12963 Tz (at ) Tj 0.777778 0 Td 58.333333 Tz (405 ) Tj 1.341667 0 Td 58.333333 Tz (nm. ) Tj 1.302778 0 Td 63.734568 Tz (The ) Tj 1.380556 0 Td 52.932099 Tz (formation ) Tj 3.111111 0 Td 59.953704 Tz (of ) Tj 0.855556 0 Td 58.873457 Tz (liposome-tem ) Tj 51.428571 0 0 51.428571 0 753.315589 Tm 25.297222 0 Td 49.691358 Tz (plated ) Tj 2.061111 0 Td 49.109687 Tz (nanoparticles ) Tj 4.122222 0 Td 60.493827 Tz (was ) Tj 1.341667 0 Td 54.73251 Tz (confirmed ) Tj 3.188889 0 Td 61.574074 Tz (by ) Tj 0.972222 0 Td 85.339506 Tz (TEM ) Tj 1.827778 0 Td 51.203704 Tz (\(FIG. ) Tj 1.808333 0 Td 52.662037 Tz (3B\). ) Tj 1.555556 0 Td 50.231481 Tz (In ) Tj 51.428571 0 0 51.428571 0 712.262045 Tm 25.297222 0 Td 49.074074 Tz (control ) Tj 2.216667 0 Td 51.58179 Tz (experiments, ) Tj 3.869444 0 Td 56.17284 Tz (performed ) Tj 3.188889 0 Td 55.740741 Tz (under ) Tj 1.808333 0 Td 46.090535 Tz (identical ) Tj 2.663889 0 Td 49.907407 Tz (conditions ) Tj 3.169444 0 Td 48.611111 Tz (in ) Tj 51.428571 0 0 51.428571 0 668.931707 Tm 25.277778 0 Td 50.771605 Tz (the ) Tj 1.088889 0 Td 55.092593 Tz (absence ) Tj 2.508333 0 Td 56.712963 Tz (of ) Tj 0.758333 0 Td 58.333333 Tz (a ) Tj 0.544444 0 Td 46.450617 Tz (free-radical ) Tj 3.558333 0 Td 40.185185 Tz (initiator, ) Tj 2.663889 0 Td 56.712963 Tz (no ) Tj 0.894444 0 Td 49.358974 Tz (nanoparticles ) Tj 4.083333 0 Td 58.333333 Tz (were ) Tj 51.428571 0 0 51.428571 0 629.110112 Tm 25.297222 0 Td 57.037037 Tz (found ) Tj 1.866667 0 Td 59.953704 Tz (by ) Tj 0.894444 0 Td 85.339506 Tz (TEM ) Tj 1.730556 0 Td 58.333333 Tz (and ) Tj 1.244444 0 Td 82.638889 Tz (UV ) Tj 1.205556 0 Td 48.971193 Tz (analyses. ) Tj 51.428571 0 0 51.428571 0 586.346667 Tm 26.036111 0 Td 54.843305 Tz (Disappearance ) Tj 4.588889 0 Td 56.712963 Tz (of ) Tj 0.913889 0 Td 50.771605 Tz (the ) Tj 1.205556 0 Td 43.209877 Tz (initiator ) Tj 2.644444 0 Td 60.493827 Tz (was ) Tj 1.438889 0 Td 55.092593 Tz (monitored ) Tj 3.266667 0 Td 53.472222 Tz (with ) Tj 1.633333 0 Td 85.87963 Tz (UV ) Tj 51.428571 0 0 51.428571 0 547.273854 Tm 25.316667 0 Td 52.121914 Tz (spectroscopy ) Tj 3.947222 0 Td 59.953704 Tz (by ) Tj 0.972222 0 Td 51.851852 Tz (following ) Tj 2.975 0 Td 51.203704 Tz (absorption ) Tj 3.266667 0 Td 46.990741 Tz (at ) Tj 0.777778 0 Td 57.253086 Tz (253 ) Tj 1.283333 0 Td 74.537037 Tz (nm ) Tj 1.127778 0 Td 51.851852 Tz (\(FIG. ) Tj 1.769444 0 Td 54.282407 Tz (3A\). ) Tj 51.428571 0 0 51.428571 0 503.830467 Tm 25.297222 0 Td 63.734568 Tz (The ) Tj 1.341667 0 Td 44.560185 Tz (rate ) Tj 1.244444 0 Td 59.953704 Tz (of ) Tj 0.816667 0 Td 49.691358 Tz (nanoparticle ) Tj 3.752778 0 Td 56.17284 Tz (growth ) Tj 2.216667 0 Td 46.990741 Tz (correlates ) Tj 3.033333 0 Td 51.041667 Tz (well ) Tj 1.438889 0 Td 52.662037 Tz (with ) Tj 1.458333 0 Td 49.691358 Tz (the ) Tj 1.088889 0 Td 45.37037 Tz (rate ) Tj 51.428571 0 0 51.428571 0 462.80344 Tm 25.297222 0 Td 58.333333 Tz (of ) Tj 0.816667 0 Td 42.849794 Tz (initiator ) Tj 2.469444 0 Td 52.849003 Tz (disappearance ) Tj 4.297222 0 Td 52.5 Tz (\(FIG. ) Tj 1.788889 0 Td 51.851852 Tz (3C\). ) Tj 1.477778 0 Td 48.611111 Tz (In ) Tj 0.777778 0 Td 55.092593 Tz (our ) Tj 1.166667 0 Td 46.990741 Tz (setup, ) Tj 1.905556 0 Td 49.691358 Tz (the ) Tj 1.088889 0 Td 57.037037 Tz (major ) Tj 51.428571 0 0 51.428571 0 420.190955 Tm 25.297222 0 Td 49.537037 Tz (portion ) Tj 2.313889 0 Td 59.953704 Tz (of ) Tj 0.855556 0 Td 49.691358 Tz (the ) Tj 1.127778 0 Td 42.849794 Tz (initiator ) Tj 2.547222 0 Td 83.449074 Tz (DMPA ) Tj 2.236111 0 Td 38.888889 Tz (is ) Tj 0.7 0 Td 50 Tz (located ) Tj 2.313889 0 Td 51.311728 Tz (within ) Tj 2.1 0 Td 49.691358 Tz (the ) Tj 1.088889 0 Td 44.965278 Tz (bilayer. ) Tj 51.428571 0 0 51.428571 0 378.943396 Tm 25.297222 0 Td 61.111111 Tz (Aqueous ) Tj 2.975 0 Td 45.694444 Tz (solubility ) Tj 3.130556 0 Td 61.574074 Tz (of ) Tj 1.05 0 Td 48.611111 Tz (the ) Tj 1.283333 0 Td 42.849794 Tz (initiator ) Tj 2.683333 0 Td 61.574074 Tz (was ) Tj 1.497222 0 Td 52.211934 Tz (estimated ) Tj 3.208333 0 Td 46.990741 Tz (to ) Tj 0.952778 0 Td 58.333333 Tz (be ) Tj 57.142857 0 0 57.142857 0 338.645833 Tm 22.7675 0 Td 48.237179 Tz (approximately ) Tj 4.1125 0 Td 55.416667 Tz (1.5x10" ) Tj 2.6075 0 Td 93.333333 Tz (M ) Tj 0.8575 0 Td 51.770833 Tz (from ) Tj 1.54 0 Td 44.722222 Tz (the ) Tj 1.085 0 Td 77.291667 Tz (UV ) Tj 1.2075 0 Td 49.21875 Tz (spectrum ) Tj 2.6775 0 Td 53.958333 Tz (of ) Tj 0.8225 0 Td 44.722222 Tz (the ) Tj 51.428571 0 0 51.428571 0 294.214198 Tm 25.316667 0 Td 48.251029 Tz (saturated ) Tj 2.8 0 Td 57.407407 Tz (aqueous ) Tj 2.663889 0 Td 47.800926 Tz (solution ) Tj 2.547222 0 Td 58.333333 Tz (of ) Tj 0.836111 0 Td 72.592593 Tz (DMPA. ) Tj 2.411111 0 Td 53.472222 Tz (This ) Tj 1.497222 0 Td 50.605413 Tz (concentration ) Tj 4.219444 0 Td 38.888889 Tz (is ) Tj 40 0 0 40 0 259 Tm 32.575 0 Td 83.333333 Tz (much ) Tj 2.325 0 Td 71.666667 Tz (lower ) Tj 2.4 0 Td 66.666667 Tz (than ) Tj 1.95 0 Td 62.5 Tz (the ) Tj 1.4 0 Td 65.064103 Tz (concentration ) Tj 5.4 0 Td 75 Tz (of ) Tj 1.1 0 Td 57.638889 Tz (silver ) Tj 2.375 0 Td 63.541667 Tz (ions ) Tj 1.825 0 Td 71.875 Tz (used ) Tj 2.025 0 Td 67.708333 Tz (here ) Tj 51.428571 0 0 51.428571 0 210.618454 Tm 25.316667 0 Td 47.314815 Tz (\(0.01 ) Tj 1.672222 0 Td 58.333333 Tz (M\). ) Tj 1.283333 0 Td 83.449074 Tz (DMPA ) Tj 2.197222 0 Td 50.771605 Tz (dissolved ) Tj 2.936111 0 Td 43.75 Tz (in ) Tj 0.719444 0 Td 54.444444 Tz (water ) Tj 1.827778 0 Td 66.975309 Tz (may ) Tj 1.419444 0 Td 53.472222 Tz (seed ) Tj 1.477778 0 Td 48.611111 Tz (the ) Tj 1.069444 0 Td 52.932099 Tz (formation ) Tj 51.428571 0 0 51.428571 0 170.191489 Tm 25.297222 0 Td 58.333333 Tz (of ) Tj 0.913889 0 Td 47.685185 Tz (nanoparticles. ) Tj 4.336111 0 Td 61.574074 Tz (Most ) Tj 1.769444 0 Td 58.333333 Tz (of ) Tj 0.875 0 Td 50.771605 Tz (the ) Tj 1.205556 0 Td 48.611111 Tz (data ) Tj 1.477778 0 Td 45.37037 Tz (in ) Tj 0.875 0 Td 53.472222 Tz (FIG. ) Tj 1.594444 0 Td 71.296296 Tz (3C ) Tj 1.147222 0 Td 64.814815 Tz (come ) Tj 1.866667 0 Td 59.143519 Tz (from ) Tj ET Q endstream endobj 160 0 obj << /Length 1 >> stream q endstream endobj 161 0 obj << /Length 48954 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 62.857143 0 0 62.857143 0 3023 Tm 17.325 0 Td 83.522727 Tz (US ) Tj 1.209091 0 Td 57.744108 Tz (9.248,441 ) Tj 3.420455 0 Td 74.242424 Tz (B2 ) Tj 51.428571 0 0 51.428571 0 2915.482436 Tm 6.377778 0 Td 84.259259 Tz (DMPA ) Tj 2.119444 0 Td 50.555556 Tz (associated ) Tj 3.130556 0 Td 52.662037 Tz (with ) Tj 1.361111 0 Td 50.771605 Tz (the ) Tj 1.030556 0 Td 44.155093 Tz (bilayer. ) Tj 2.255556 0 Td 79.398148 Tz (We ) Tj 1.05 0 Td 56.712963 Tz (have ) Tj 1.458333 0 Td 50.555556 Tz (previously ) Tj 3.169444 0 Td 63.518519 Tz (shown ) Tj 51.428571 0 0 51.428571 0 2872.828087 Tm 6.338889 0 Td 46.990741 Tz (that ) Tj 1.283333 0 Td 48.611111 Tz (the ) Tj 1.05 0 Td 48.611111 Tz (release ) Tj 2.158333 0 Td 58.333333 Tz (of ) Tj 0.797222 0 Td 55.092593 Tz (hydrophobic ) Tj 3.830556 0 Td 54.012346 Tz (molecules ) Tj 3.111111 0 Td 56.712963 Tz (from ) Tj 1.555556 0 Td 49.691358 Tz (the ) Tj 1.030556 0 Td 48.611111 Tz (bilayer ) Tj 2.197222 0 Td 38.888889 Tz (is ) Tj 58.571429 0 0 58.571429 0 2830.483061 Tm 5.6 0 Td 43.252033 Tz (slow. ) Tj 1.809756 0 Td 49.186992 Tz (Without ) Tj 2.185366 0 Td 47.96748 Tz (wishing ) Tj 2.15122 0 Td 41.260163 Tz (to ) Tj 0.597561 0 Td 51.219512 Tz (be ) Tj 0.734146 0 Td 53.495935 Tz (bound ) Tj 1.707317 0 Td 52.642276 Tz (by ) Tj 0.768293 0 Td 50.271003 Tz (any ) Tj 1.02439 0 Td 41.869919 Tz (theory, ) Tj 1.878049 0 Td 28.455285 Tz (it ) Tj 0.478049 0 Td 34.146341 Tz (is ) Tj 0.529268 0 Td 40.785908 Tz (likely ) Tj 51.428571 0 0 51.428571 0 2783.846154 Tm 6.338889 0 Td 46.990741 Tz (that ) Tj 1.225 0 Td 48.611111 Tz (electron ) Tj 2.469444 0 Td 46.585648 Tz (transfer ) Tj 2.333333 0 Td 43.75 Tz (at ) Tj 0.661111 0 Td 48.611111 Tz (the ) Tj 0.991667 0 Td 49.358974 Tz (water/bilayer ) Tj 3.947222 0 Td 46.8107 Tz (interface ) Tj 2.644444 0 Td 48.611111 Tz (contributes ) Tj 47.857143 0 0 47.857143 0 2745.183486 Tm 6.81194 0 Td 50.497512 Tz (to ) Tj 0.814925 0 Td 54.560531 Tz (the ) Tj 1.149254 0 Td 60.945274 Tz (growth ) Tj 2.402985 0 Td 62.686567 Tz (of ) Tj 0.877612 0 Td 51.243781 Tz (nanoparticles. ) Tj 14.167164 0 Td 45.273632 Tz (5 ) Tj 51.428571 0 0 51.428571 0 2697.710744 Tm 7.097222 0 Td 62.654321 Tz (The ) Tj 1.516667 0 Td 55.092593 Tz (scope ) Tj 2.041667 0 Td 58.333333 Tz (of ) Tj 1.011111 0 Td 52.932099 Tz (simultaneous ) Tj 4.2 0 Td 52.175926 Tz (templating ) Tj 3.5 0 Td 56.17284 Tz (can ) Tj 1.4 0 Td 58.333333 Tz (be ) Tj 1.108333 0 Td 47.222222 Tz (further ) Tj 51.428571 0 0 51.428571 0 2653.701031 Tm 6.358333 0 Td 57.928241 Tz (expanded ) Tj 3.091667 0 Td 61.574074 Tz (by ) Tj 1.088889 0 Td 52.5 Tz (using ) Tj 1.925 0 Td 50.356125 Tz (water-soluble ) Tj 4.258333 0 Td 42.777778 Tz (initiators ) Tj 2.916667 0 Td 45.37037 Tz (in ) Tj 0.875 0 Td 49.826389 Tz (addition ) Tj 2.741667 0 Td 46.990741 Tz (to ) Tj 51.428571 0 0 51.428571 0 2612.493947 Tm 6.338889 0 Td 55.681818 Tz (hydrophobic ) Tj 3.888889 0 Td 55.092593 Tz (ones ) Tj 1.516667 0 Td 45.37037 Tz (in ) Tj 0.758333 0 Td 51.851852 Tz (order ) Tj 1.730556 0 Td 45.37037 Tz (to ) Tj 0.738889 0 Td 52.849003 Tz (independently ) Tj 4.355556 0 Td 51.041667 Tz (vary ) Tj 1.419444 0 Td 56.893004 Tz (concentra ) Tj 51.428571 0 0 51.428571 0 2567.091358 Tm 6.338889 0 Td 47.800926 Tz (tion ) Tj 1.341667 0 Td 58.333333 Tz (and ) Tj 1.244444 0 Td 50.231481 Tz (nature ) Tj 2.002778 0 Td 56.712963 Tz (of ) Tj 0.777778 0 Td 49.421296 Tz (ions ) Tj 1.380556 0 Td 46.990741 Tz (in ) Tj 0.738889 0 Td 50.771605 Tz (the ) Tj 1.069444 0 Td 56.944444 Tz (aqueous ) Tj 2.605556 0 Td 51.851852 Tz (core ) Tj 1.4 0 Td 59.41358 Tz (and ) Tj 1.225 0 Td 55.976431 Tz (hydrophobic ) Tj 51.428571 0 0 51.428571 0 2523.461347 Tm 6.358333 0 Td 64.409722 Tz (monomers ) Tj 3.286111 0 Td 45.37037 Tz (in ) Tj 0.777778 0 Td 49.691358 Tz (the ) Tj 1.088889 0 Td 44.560185 Tz (bilayer. ) Tj 2.372222 0 Td 85.87963 Tz (UV ) Tj 1.263889 0 Td 49.074074 Tz (spectra ) Tj 2.294444 0 Td 47.530864 Tz (reveal ) Tj 1.944444 0 Td 48.611111 Tz (the ) Tj 1.088889 0 Td 53.06713 Tz (presence ) Tj 2.741667 0 Td 58.333333 Tz (of ) Tj 51.428571 0 0 51.428571 0 2483.122249 Tm 6.358333 0 Td 49.608262 Tz (nanoparticles ) Tj 4.161111 0 Td 45.37037 Tz (in ) Tj 0.836111 0 Td 50.771605 Tz (the ) Tj 1.166667 0 Td 53.472222 Tz (nanocapsules ) Tj 4.141667 0 Td 46.018519 Tz (after ) Tj 1.594444 0 Td 49.691358 Tz (the ) Tj 1.147222 0 Td 53.009259 Tz (polymerization ) Tj 51.428571 0 0 51.428571 0 2437.86392 Tm 6.377778 0 Td 51.851852 Tz (\(FIG. ) Tj 1.866667 0 Td 54.282407 Tz (3D\). ) Tj 1.652778 0 Td 54.444444 Tz (Dried ) Tj 1.925 0 Td 53.472222 Tz (nanocapsules ) Tj 4.161111 0 Td 51.203704 Tz (containing ) Tj 3.383333 0 Td 44.830247 Tz (silver ) Tj 1.905556 0 Td 60.648148 Tz (nanopar ) Tj 51.428571 0 0 51.428571 0 2390.862485 Tm 6.338889 0 Td 43.209877 Tz (ticles ) Tj 1.711111 0 Td 48.611111 Tz (exhibit ) Tj 2.177778 0 Td 46.064815 Tz (characteristic ) Tj 4.063889 0 Td 52.932099 Tz (yellow ) Tj 2.119444 0 Td 50.555556 Tz (color ) Tj 1.691667 0 Td 42.12963 Tz (in ) Tj 0.680556 0 Td 48.611111 Tz (contrast ) Tj 2.508333 0 Td 45.37037 Tz (to ) Tj 0.7 0 Td 61.574074 Tz (empty ) Tj 51.428571 0 0 51.428571 0 2349.727059 Tm 6.358333 0 Td 53.472222 Tz (nanocapsules ) Tj 4.063889 0 Td 52.5 Tz (\(FIG. ) Tj 1.75 0 Td 60.493827 Tz (3D, ) Tj 1.302778 0 Td 41.666667 Tz (inset\). ) Tj 51.428571 0 0 51.428571 0 2306.521739 Tm 7.116667 0 Td 58.333333 Tz (Based ) Tj 2.177778 0 Td 56.712963 Tz (on ) Tj 1.108333 0 Td 46.666667 Tz (sizes ) Tj 1.808333 0 Td 58.333333 Tz (of ) Tj 1.05 0 Td 53.20216 Tz (nanocapsules ) Tj 4.219444 0 Td 60.493827 Tz (and ) Tj 1.516667 0 Td 47.685185 Tz (nanoparticles, ) Tj 4.433333 0 Td 34.027778 Tz (it ) Tj 51.428571 0 0 51.428571 0 2262.197829 Tm 6.358333 0 Td 52.777778 Tz (appears ) Tj 2.352778 0 Td 46.990741 Tz (that ) Tj 1.263889 0 Td 45.37037 Tz (less ) Tj 1.244444 0 Td 51.851852 Tz (than ) Tj 1.4 0 Td 79.398148 Tz (5% ) Tj 1.147222 0 Td 55.092593 Tz (of ) Tj 0.758333 0 Td 54.208754 Tz (nanocapsule ) Tj 3.733333 0 Td 59.41358 Tz (Volume ) Tj 2.333333 0 Td 37.268519 Tz (is ) Tj 0.602778 0 Td 55.497685 Tz (occupied ) Tj 51.428571 0 0 51.428571 0 2218.937122 Tm 6.338889 0 Td 61.574074 Tz (by ) Tj 0.894444 0 Td 48.611111 Tz (a ) Tj 0.486111 0 Td 49.691358 Tz (nanoparticle ) Tj 3.733333 0 Td 58.333333 Tz (and ) Tj 1.205556 0 Td 61.574074 Tz (more ) Tj 1.652778 0 Td 50.231481 Tz (than ) Tj 1.380556 0 Td 72.376543 Tz (95% ) Tj 1.477778 0 Td 56.712963 Tz (of ) Tj 0.758333 0 Td 54.503367 Tz (nanocapsule ) Tj 3.752778 0 Td 59.953704 Tz (volume ) Tj 51.428571 0 0 51.428571 0 2175.704762 Tm 6.358333 0 Td 38.888889 Tz (is ) Tj 0.622222 0 Td 48.251029 Tz (available ) Tj 2.722222 0 Td 48.611111 Tz (for ) Tj 0.991667 0 Td 54.095442 Tz (co-entrapment ) Tj 4.355556 0 Td 51.851852 Tz (of ) Tj 0.7 0 Td 51.203704 Tz (other ) Tj 1.652778 0 Td 49.537037 Tz (species ) Tj 2.236111 0 Td 40.509259 Tz (\(e.g., ) Tj 1.594444 0 Td 51.311728 Tz (drugs\) ) Tj 2.002778 0 Td 51.851852 Tz (or ) Tj 51.428571 0 0 51.428571 0 2129.521092 Tm 6.358333 0 Td 49.691358 Tz (for ) Tj 1.088889 0 Td 53.06713 Tz (allowing ) Tj 2.8 0 Td 54.444444 Tz (unhindered ) Tj 3.519444 0 Td 52.662037 Tz (flow ) Tj 1.536111 0 Td 58.333333 Tz (of ) Tj 0.836111 0 Td 49.826389 Tz (analytes ) Tj 2.644444 0 Td 55.092593 Tz (or ) Tj 0.894444 0 Td 47.314815 Tz (substrates ) Tj 3.072222 0 Td 61.574074 Tz (and ) Tj 51.428571 0 0 51.428571 0 2089.183922 Tm 6.358333 0 Td 49.331276 Tz (products. ) Tj 2.916667 0 Td 50.555556 Tz (Sizes ) Tj 1.75 0 Td 56.712963 Tz (of ) Tj 0.797222 0 Td 54.282407 Tz (both ) Tj 1.555556 0 Td 53.472222 Tz (nanocapsules ) Tj 4.063889 0 Td 59.41358 Tz (and ) Tj 1.322222 0 Td 49.109687 Tz (nanoparticles ) Tj 4.044444 0 Td 58.333333 Tz (can ) Tj 51.428571 0 0 51.428571 0 2042.991556 Tm 6.338889 0 Td 59.953704 Tz (be ) Tj 0.913889 0 Td 49.151235 Tz (varied ) Tj 1.905556 0 Td 59.953704 Tz (by ) Tj 0.952778 0 Td 55.092593 Tz (changing ) Tj 2.819444 0 Td 50.771605 Tz (the ) Tj 1.069444 0 Td 55.497685 Tz (liposome ) Tj 2.819444 0 Td 53.472222 Tz (diameter ) Tj 2.722222 0 Td 58.333333 Tz (and ) Tj 1.205556 0 Td 56.893004 Tz (concentra ) Tj 51.428571 0 0 51.428571 0 2000.652553 Tm 6.338889 0 Td 47.800926 Tz (tion ) Tj 1.438889 0 Td 55.092593 Tz (of ) Tj 0.855556 0 Td 53.148148 Tz (metal ) Tj 1.866667 0 Td 39.969136 Tz (salts. ) Tj 1.75 0 Td 51.279956 Tz (Bilayer-templated ) Tj 5.502778 0 Td 53.472222 Tz (nanocapsules ) Tj 4.141667 0 Td 54.012346 Tz (can ) Tj 1.225 0 Td 59.953704 Tz (be ) Tj 51.428571 0 0 51.428571 0 1957.826138 Tm 6.358333 0 Td 52.572016 Tz (imprinted ) Tj 2.975 0 Td 53.472222 Tz (with ) Tj 1.4 0 Td 55.092593 Tz (nanopores ) Tj 3.091667 0 Td 55.632716 Tz (having ) Tj 2.119444 0 Td 48.935185 Tz (controlled ) Tj 3.052778 0 Td 43.425926 Tz (size, ) Tj 1.419444 0 Td 46.585648 Tz (density, ) Tj 2.352778 0 Td 60.493827 Tz (and ) Tj 58.571429 0 0 58.571429 0 1912.783572 Tm 5.582927 0 Td 48.018293 Tz (chemical ) Tj 2.629268 0 Td 46.476965 Tz (environment. ) Tj 3.978049 0 Td 48.057814 Tz (Formation ) Tj 2.953659 0 Td 49.796748 Tz (of ) Tj 0.870732 0 Td 48.057814 Tz (nanopores ) Tj 2.936585 0 Td 34.146341 Tz (is ) Tj 0.734146 0 Td 51.930894 Tz (done ) Tj 51.428571 0 0 51.428571 0 1874.351592 Tm 6.338889 0 Td 53.148148 Tz (using ) Tj 1.963889 0 Td 54.282407 Tz (pore-forming ) Tj 4.258333 0 Td 51.851852 Tz (templates ) Tj 3.169444 0 Td 46.180556 Tz (that ) Tj 1.477778 0 Td 49.691358 Tz (are ) Tj 1.302778 0 Td 50.771605 Tz (co-dissolved ) Tj 4.025 0 Td 54.282407 Tz (with ) Tj 51.428571 0 0 51.428571 0 1829.044776 Tm 6.358333 0 Td 64.409722 Tz (monomers ) Tj 3.325 0 Td 50.771605 Tz (within ) Tj 2.119444 0 Td 48.611111 Tz (the ) Tj 1.108333 0 Td 48.611111 Tz (bilayer ) Tj 2.255556 0 Td 45.775463 Tz (interior ) Tj 2.372222 0 Td 59.41358 Tz (and ) Tj 1.322222 0 Td 45.37037 Tz (that ) Tj 1.302778 0 Td 50.771605 Tz (are ) Tj 1.166667 0 Td 60.185185 Tz (removed ) Tj 57.142857 0 0 57.142857 0 1790.88 Tm 5.7225 0 Td 40.833333 Tz (after ) Tj 1.505 0 Td 44.722222 Tz (the ) Tj 1.085 0 Td 46.083333 Tz (polymerization. ) Tj 4.7425 0 Td 44.607843 Tz (Functionalization ) Tj 4.8475 0 Td 52.5 Tz (of ) Tj 0.8925 0 Td 48.935185 Tz (nanopores ) Tj 51.428571 0 0 51.428571 0 1752.247944 Tm 6.358333 0 Td 56.388889 Tz (opens ) Tj 1.886111 0 Td 48.611111 Tz (opportunities ) Tj 3.986111 0 Td 47.530864 Tz (for ) Tj 1.011111 0 Td 48.611111 Tz (regulating ) Tj 3.052778 0 Td 51.311728 Tz (permeability ) Tj 3.85 0 Td 58.333333 Tz (of ) Tj 0.777778 0 Td 60.358796 Tz (nano-cap ) Tj 51.428571 0 0 51.428571 0 1705.806658 Tm 6.377778 0 Td 44.830247 Tz (Sules, ) Tj 2.002778 0 Td 51.131687 Tz (including ) Tj 3.130556 0 Td 53.472222 Tz (response ) Tj 2.916667 0 Td 48.611111 Tz (to ) Tj 0.972222 0 Td 48.611111 Tz (external ) Tj 2.722222 0 Td 45.37037 Tz (stimuli. ) Tj 2.586111 0 Td 52.5 Tz (Controlled ) Tj 51.428571 0 0 51.428571 0 1664.389744 Tm 6.358333 0 Td 64.409722 Tz (membrane ) Tj 3.383333 0 Td 47.890947 Tz (transport ) Tj 2.877778 0 Td 56.17284 Tz (can ) Tj 1.302778 0 Td 59.953704 Tz (be ) Tj 1.030556 0 Td 48.070988 Tz (useful ) Tj 2.080556 0 Td 47.530864 Tz (for ) Tj 1.127778 0 Td 46.8107 Tz (selective ) Tj 2.819444 0 Td 54.012346 Tz (uptake ) Tj 2.236111 0 Td 58.333333 Tz (of ) Tj 52.857143 0 0 52.857143 0 1622.321519 Tm 6.186486 0 Td 48.085586 Tz (analytes ) Tj 2.497297 0 Td 56.756757 Tz (and ) Tj 1.210811 0 Td 46.036036 Tz (substrates ) Tj 2.97027 0 Td 50.45045 Tz (or ) Tj 0.775676 0 Td 46.246246 Tz (for ) Tj 0.964865 0 Td 49.399399 Tz (the ) Tj 1.059459 0 Td 46.846847 Tz (release ) Tj 2.156757 0 Td 55.18018 Tz (of ) Tj 0.775676 0 Td 46.396396 Tz (nanoparticles. ) Tj 51.428571 0 0 51.428571 0 1583.009986 Tm 7.097222 0 Td 87.5 Tz (A ) Tj 1.011111 0 Td 54.012346 Tz (simple ) Tj 2.488889 0 Td 58.873457 Tz (method ) Tj 2.644444 0 Td 48.611111 Tz (for ) Tj 1.341667 0 Td 51.131687 Tz (obtaining ) Tj 3.286111 0 Td 52.5 Tz (metal ) Tj 2.119444 0 Td 49.109687 Tz (nanoparticles ) Tj 51.428571 0 0 51.428571 0 1540.749415 Tm 6.358333 0 Td 53.292181 Tz (entrapped ) Tj 3.013889 0 Td 43.75 Tz (in ) Tj 0.641667 0 Td 55.092593 Tz (hollow ) Tj 2.138889 0 Td 58.333333 Tz (polymer ) Tj 2.547222 0 Td 51.041667 Tz (capsules ) Tj 2.586111 0 Td 54.282407 Tz (with ) Tj 1.438889 0 Td 48.935185 Tz (controlled ) Tj 3.013889 0 Td 69.351852 Tz (perme ) Tj 51.428571 0 0 51.428571 0 1498.920455 Tm 6.358333 0 Td 43.981481 Tz (ability ) Tj 2.605556 0 Td 54.6875 Tz (promises ) Tj 3.363889 0 Td 50.605413 Tz (technological ) Tj 4.686111 0 Td 55.092593 Tz (advances ) Tj 3.422222 0 Td 45.37037 Tz (in ) Tj 1.322222 0 Td 49.537037 Tz (diverse ) Tj 58.571429 0 0 58.571429 0 1455.159091 Tm 5.582927 0 Td 41.588493 Tz (applications, ) Tj 3.44878 0 Td 47.662602 Tz (such ) Tj 1.34878 0 Td 44.105691 Tz (as ) Tj 0.7 0 Td 43.038618 Tz (creation ) Tj 2.270732 0 Td 49.796748 Tz (of ) Tj 0.7 0 Td 42.165558 Tz (theranostic ) Tj 2.987805 0 Td 42.682927 Tz (devices, ) Tj 2.765854 0 Td 61.653117 Tz (nan ) Tj 58.571429 0 0 58.571429 0 1411.700865 Tm 5.582927 0 Td 41.13082 Tz (oreactors,' ) Tj 3.192683 0 Td 48.373984 Tz (or ) Tj 0.75122 0 Td 42.327236 Tz (sensors, ) Tj 2.236585 0 Td 35.853659 Tz (e.g., ) Tj 1.297561 0 Td 46.239837 Tz (Surface-enhanced ) Tj 4.643902 0 Td 59.756098 Tz (Raman ) Tj 2.031707 0 Td 49.085366 Tz (scat ) Tj 57.142857 0 0 57.142857 0 1373.214286 Tm 5.705 0 Td 43.75 Tz (tering ) Tj 1.7325 0 Td 48.854167 Tz (\(SERS\)." ) Tj 51.428571 0 0 51.428571 0 1330.741191 Tm 7.116667 0 Td 46.990741 Tz (In ) Tj 0.680556 0 Td 58.738426 Tz (Summary, ) Tj 2.955556 0 Td 71.296296 Tz (we ) Tj 0.952778 0 Td 56.712963 Tz (have ) Tj 1.497222 0 Td 54.282407 Tz (demonstrated ) Tj 4.005556 0 Td 53.20216 Tz (simultaneous ) Tj 3.947222 0 Td 49.331276 Tz (synthesis ) Tj 51.428571 0 0 51.428571 0 1291.541317 Tm 6.358333 0 Td 58.333333 Tz (of ) Tj 0.777778 0 Td 55.632716 Tz (hollow ) Tj 2.216667 0 Td 58.796296 Tz (polymer ) Tj 2.644444 0 Td 53.472222 Tz (nanocapsules ) Tj 4.044444 0 Td 59.41358 Tz (and ) Tj 1.244444 0 Td 53.652263 Tz (entrapped ) Tj 3.091667 0 Td 45.37037 Tz (silver ) Tj 1.827778 0 Td 67.24537 Tz (nano ) Tj 51.428571 0 0 51.428571 0 1249.061538 Tm 6.358333 0 Td 43.75 Tz (particles. ) Tj 2.858333 0 Td 54.282407 Tz (This ) Tj 1.575 0 Td 59.953704 Tz (method ) Tj 2.430556 0 Td 66.975309 Tz (may ) Tj 1.438889 0 Td 59.953704 Tz (be ) Tj 0.933333 0 Td 54.166667 Tz (adapted ) Tj 2.488889 0 Td 46.990741 Tz (to ) Tj 0.797222 0 Td 58.333333 Tz (a ) Tj 0.563889 0 Td 56.388889 Tz (broad ) Tj 1.944444 0 Td 53.148148 Tz (range ) Tj 1.847222 0 Td 56.712963 Tz (of ) Tj 51.428571 0 0 51.428571 0 1206.055556 Tm 6.358333 0 Td 52.391975 Tz (metals ) Tj 1.983333 0 Td 60.493827 Tz (and ) Tj 1.225 0 Td 59.053498 Tz (monomers. ) Tj 3.325 0 Td 63.518519 Tz (Newly ) Tj 2.002778 0 Td 53.877315 Tz (prepared ) Tj 2.663889 0 Td 53.472222 Tz (hybrid ) Tj 2.041667 0 Td 50.231481 Tz (nanostructures ) Tj 51.428571 0 0 51.428571 0 1169.510638 Tm 6.358333 0 Td 58.333333 Tz (open ) Tj 1.594444 0 Td 48.611111 Tz (exciting ) Tj 2.527778 0 Td 48.860399 Tz (opportunities ) Tj 4.005556 0 Td 49.691358 Tz (for ) Tj 1.011111 0 Td 46.8107 Tz (practical ) Tj 2.722222 0 Td 46.866097 Tz (applications. ) Tj 30 0 0 30 0 2547 Tm 41.666667 0 Td 75 Tz (10 ) Tj 30 0 0 30 0 2339 Tm 41.666667 0 Td 72.222222 Tz (15 ) Tj 30 0 0 30 0 1923 Tm 41.6 0 Td 77.777778 Tz (25 ) Tj 30 0 0 30 0 1716 Tm 41.6 0 Td 80.555556 Tz (30 ) Tj 30 0 0 30 0 1507 Tm 41.6 0 Td 77.777778 Tz (35 ) Tj 30 0 0 30 0 1299 Tm 41.566667 0 Td 83.333333 Tz (40 ) Tj 35.714286 0 0 35.714286 0 1091 Tm 16.772 0 Td 109.2 Tz (REFERENCES ) Tj 6.86 0 Td 101.733333 Tz (CITED ) Tj 11.284 0 Td 67.666667 Tz (45 ) Tj 51.428571 0 0 51.428571 0 1001.040559 Tm 6.436111 0 Td 37.268519 Tz (1. ) Tj 0.738889 0 Td 45.37037 Tz (\(a\) ) Tj 1.069444 0 Td 46.990741 Tz (S. ) Tj 0.836111 0 Td 37.268519 Tz (J. ) Tj 0.758333 0 Td 50.231481 Tz (Li ) Tj 0.894444 0 Td 58.333333 Tz (and ) Tj 1.322222 0 Td 46.990741 Tz (S. ) Tj 0.836111 0 Td 60.277778 Tz (Gong, ) Tj 2.041667 0 Td 56.712963 Tz (Adv. ) Tj 1.691667 0 Td 49.151235 Tz (Funct. ) Tj 2.061111 0 Td 56.712963 Tz (Mater, ) Tj 2.352778 0 Td 53.148148 Tz (2009, ) Tj 1.925 0 Td 46.450617 Tz (19, ) Tj 51.428571 0 0 51.428571 0 958.994413 Tm 7.097222 0 Td 55.416667 Tz (2601-2606; ) Tj 3.577778 0 Td 47.530864 Tz (\(b\) ) Tj 1.05 0 Td 40.509259 Tz (J. ) Tj 0.719444 0 Td 38.888889 Tz (P. ) Tj 0.758333 0 Td 57.685185 Tz (Deng, ) Tj 1.963889 0 Td 61.574074 Tz (W. ) Tj 0.972222 0 Td 56.712963 Tz (C. ) Tj 0.913889 0 Td 54.282407 Tz (Shih ) Tj 1.555556 0 Td 59.41358 Tz (and ) Tj 1.283333 0 Td 55.092593 Tz (C. ) Tj 0.816667 0 Td 51.851852 Tz (Y. ) Tj 0.875 0 Td 64.00463 Tz (Mou, ) Tj 1.769444 0 Td 37.268519 Tz (J. ) Tj 51.428571 0 0 51.428571 0 918.707071 Tm 7.097222 0 Td 51.851852 Tz (Phys. ) Tj 1.711111 0 Td 64.166667 Tz (Chem. ) Tj 2.080556 0 Td 55.092593 Tz (C, ) Tj 0.816667 0 Td 53.796296 Tz (2007, ) Tj 1.847222 0 Td 55.555556 Tz (111,9723-9728; ) Tj 4.841667 0 Td 49.259259 Tz (\(c\)Y. ) Tj 1.672222 0 Td 57.685185 Tz (Deng, ) Tj 1.808333 0 Td 50.231481 Tz (Y. ) Tj 0.758333 0 Td 48.611111 Tz (Cai, ) Tj 51.428571 0 0 51.428571 0 875.930988 Tm 7.097222 0 Td 48.611111 Tz (Z. ) Tj 0.758333 0 Td 54.282407 Tz (Sun, ) Tj 1.419444 0 Td 38.888889 Tz (J. ) Tj 0.641667 0 Td 48.611111 Tz (Liu, ) Tj 1.322222 0 Td 53.472222 Tz (C. ) Tj 0.836111 0 Td 47.800926 Tz (Liu, ) Tj 1.302778 0 Td 35.648148 Tz (J. ) Tj 0.602778 0 Td 54.282407 Tz (Wei, ) Tj 1.438889 0 Td 63.194444 Tz (W. ) Tj 0.952778 0 Td 43.209877 Tz (Li, ) Tj 0.933333 0 Td 55.092593 Tz (C. ) Tj 0.836111 0 Td 48.611111 Tz (Liu, ) Tj 1.244444 0 Td 48.611111 Tz (Y. ) Tj 0.738889 0 Td 69.675926 Tz (Wang ) Tj 1.788889 0 Td 59.41358 Tz (and ) Tj 1.244444 0 Td 53.472222 Tz (D. ) Tj 48.571429 0 0 48.571429 0 835 Tm 7.514706 0 Td 58.333333 Tz (Zhao, ) Tj 1.935294 0 Td 42.892157 Tz (J. ) Tj 0.679412 0 Td 73.202614 Tz (Am. ) Tj 1.523529 0 Td 67.941176 Tz (Chem. ) Tj 2.223529 0 Td 51.470588 Tz (Soc., ) Tj 1.729412 0 Td 57.647059 Tz (2010, ) Tj 1.997059 0 Td 53.186275 Tz (132, ) Tj 1.461765 0 Td 58.676471 Tz (8466-8473. ) Tj 51.428571 0 0 51.428571 0 793.496183 Tm 6.358333 0 Td 43.75 Tz (2. ) Tj 0.738889 0 Td 44.290123 Tz (\(a\) ) Tj 0.933333 0 Td 58.333333 Tz (X. ) Tj 0.894444 0 Td 55.092593 Tz (N. ) Tj 0.855556 0 Td 59.41358 Tz (Xu, ) Tj 1.225 0 Td 63.194444 Tz (W. ) Tj 0.952778 0 Td 37.268519 Tz (J. ) Tj 0.661111 0 Td 57.973251 Tz (Brownlow, ) Tj 3.325 0 Td 53.472222 Tz (S.V. ) Tj 1.477778 0 Td 52.932099 Tz (Kyriacou, ) Tj 3.013889 0 Td 56.712963 Tz (Q. ) Tj 0.875 0 Td 72.376543 Tz (Wan ) Tj 1.458333 0 Td 59.41358 Tz (and ) Tj 51.428571 0 0 51.428571 0 752.178947 Tm 7.097222 0 Td 37.268519 Tz (J. ) Tj 0.661111 0 Td 37.268519 Tz (J. ) Tj 0.680556 0 Td 48.070988 Tz (Viola, ) Tj 1.983333 0 Td 51.602564 Tz (Biochemistry, ) Tj 4.238889 0 Td 55.092593 Tz (2004, ) Tj 1.866667 0 Td 49.691358 Tz (43, ) Tj 1.225 0 Td 55.092593 Tz (10400-10413; ) Tj 4.219444 0 Td 47.530864 Tz (\(b\) ) Tj 1.069444 0 Td 63.194444 Tz (W. ) Tj 51.428571 0 0 51.428571 0 712.080395 Tm 7.116667 0 Td 53.472222 Tz (Sun, ) Tj 1.555556 0 Td 58.333333 Tz (G. ) Tj 0.991667 0 Td 61.574074 Tz (Wang, ) Tj 2.138889 0 Td 56.712963 Tz (N. ) Tj 0.991667 0 Td 59.953704 Tz (Fang ) Tj 1.691667 0 Td 59.41358 Tz (and ) Tj 1.419444 0 Td 45.37037 Tz (E. ) Tj 0.836111 0 Td 46.990741 Tz (S. ) Tj 0.836111 0 Td 56.17284 Tz (Yeung, ) Tj 2.275 0 Td 51.851852 Tz (Anal. ) Tj 1.866667 0 Td 69.351852 Tz (Chem. ) Tj 51.428571 0 0 51.428571 0 668.358491 Tm 7.097222 0 Td 53.796296 Tz (2009, ) Tj 1.827778 0 Td 49.691358 Tz (81, ) Tj 1.069444 0 Td 55.740741 Tz (9203-9208; ) Tj 3.577778 0 Td 44.290123 Tz (\(c\) ) Tj 0.972222 0 Td 55.092593 Tz (C. ) Tj 0.875 0 Td 38.888889 Tz (J. ) Tj 0.680556 0 Td 58.333333 Tz (Murphy, ) Tj 2.605556 0 Td 56.712963 Tz (A. ) Tj 0.913889 0 Td 68.055556 Tz (M. ) Tj 1.030556 0 Td 51.851852 Tz (Gole, ) Tj 1.769444 0 Td 48.611111 Tz (S. ) Tj 0.816667 0 Td 46.990741 Tz (E. ) Tj 51.428571 0 0 51.428571 0 628.800515 Tm 7.116667 0 Td 55.092593 Tz (Hunyadi, ) Tj 2.761111 0 Td 37.268519 Tz (J. ) Tj 0.602778 0 Td 63.194444 Tz (W. ) Tj 0.933333 0 Td 50.231481 Tz (Stone, ) Tj 1.963889 0 Td 53.472222 Tz (P.N. ) Tj 1.438889 0 Td 48.070988 Tz (Sisco, ) Tj 1.866667 0 Td 55.092593 Tz (A. ) Tj 0.797222 0 Td 48.971193 Tz (Alkilany, ) Tj 2.838889 0 Td 48.611111 Tz (B. ) Tj 0.797222 0 Td 43.75 Tz (E. ) Tj 0.719444 0 Td 56.17284 Tz (Kinard ) Tj 48.571429 0 0 48.571429 0 586 Tm 7.514706 0 Td 61.764706 Tz (and ) Tj 1.317647 0 Td 41.176471 Tz (P. ) Tj 0.741176 0 Td 56.617647 Tz (Hankins, ) Tj 2.902941 0 Td 67.254902 Tz (Chem. ) Tj 2.223529 0 Td 67.769608 Tz (Commun., ) Tj 3.458824 0 Td 57.647059 Tz (2008, ) Tj 1.935294 0 Td 56.617647 Tz (544-557. ) Tj 51.428571 0 0 51.428571 0 545.084088 Tm 6.358333 0 Td 43.75 Tz (3. ) Tj 0.719444 0 Td 45.37037 Tz (T. ) Tj 0.777778 0 Td 57.253086 Tz (Huang, ) Tj 2.275 0 Td 38.888889 Tz (P. ) Tj 0.7 0 Td 53.472222 Tz (D. ) Tj 0.855556 0 Td 56.565657 Tz (Nallathamby ) Tj 3.927778 0 Td 58.333333 Tz (and ) Tj 1.225 0 Td 56.712963 Tz (X. ) Tj 0.894444 0 Td 56.712963 Tz (N. ) Tj 0.875 0 Td 59.41358 Tz (Xu, ) Tj 1.244444 0 Td 37.268519 Tz (J. ) Tj 0.622222 0 Td 68.055556 Tz (Am. ) Tj 1.419444 0 Td 63.518519 Tz (Chem. ) Tj 47.142857 0 0 47.142857 0 503 Tm 7.763636 0 Td 51.616162 Tz (Soc., ) Tj 1.760606 0 Td 59.393939 Tz (2008, ) Tj 2.015152 0 Td 55.681818 Tz (130, ) Tj 1.612121 0 Td 60.395623 Tz (17095-17105. ) Tj 51.428571 0 0 51.428571 0 459 Tm 6.358333 0 Td 43.75 Tz (4. ) Tj 0.719444 0 Td 43.209877 Tz (\(a\) ) Tj 0.933333 0 Td 46.666667 Tz (J.-H. ) Tj 1.594444 0 Td 49.259259 Tz (Park, ) Tj 1.613889 0 Td 58.333333 Tz (G. ) Tj 0.913889 0 Td 57.253086 Tz (von ) Tj 1.225 0 Td 53.292181 Tz (Maltzahn, ) Tj 3.091667 0 Td 46.990741 Tz (E. ) Tj 0.797222 0 Td 48.611111 Tz (Ruoslahti, ) Tj 3.091667 0 Td 45.37037 Tz (S. ) Tj 0.719444 0 Td 56.712963 Tz (N. ) Tj 0.913889 0 Td 51.851852 Tz (Bhatia ) Tj 51.428571 0 0 51.428571 0 419.179283 Tm 7.097222 0 Td 58.333333 Tz (and ) Tj 1.225 0 Td 66.435185 Tz (M. ) Tj 1.011111 0 Td 35.648148 Tz (J. ) Tj 0.661111 0 Td 44.444444 Tz (Sailor, ) Tj 2.041667 0 Td 59.953704 Tz (Angew. ) Tj 2.372222 0 Td 69.351852 Tz (Chem. ) Tj 2.294444 0 Td 39.699074 Tz (Int. ) Tj 1.225 0 Td 46.180556 Tz (Ed., ) Tj 1.283333 0 Td 54.444444 Tz (2008, ) Tj 1.847222 0 Td 48.611111 Tz (47, ) Tj 1.069444 0 Td 70.486111 Tz (7284 ) Tj 51.428571 0 0 51.428571 0 378.569571 Tm 7.097222 0 Td 53.796296 Tz (7288; ) Tj 1.847222 0 Td 47.530864 Tz (\(b\) ) Tj 1.030556 0 Td 56.712963 Tz (G. ) Tj 0.875 0 Td 53.364198 Tz (Gopalakrishnan, ) Tj 5.016667 0 Td 53.472222 Tz (C. ) Tj 0.875 0 Td 54.282407 Tz (Danelon, ) Tj 2.838889 0 Td 38.888889 Tz (P. ) Tj 0.719444 0 Td 51.851852 Tz (Izewska, ) Tj 2.702778 0 Td 66.435185 Tz (M. ) Tj 51.428571 0 0 51.428571 0 336.427822 Tm 7.116667 0 Td 58.738426 Tz (Prummer, ) Tj 3.072222 0 Td 55.092593 Tz (P-Y. ) Tj 1.613889 0 Td 48.971193 Tz (Bolinger, ) Tj 2.936111 0 Td 29.166667 Tz (I. ) Tj 0.602778 0 Td 50.231481 Tz (Geissbuhler, ) Tj 3.869444 0 Td 55.092593 Tz (D. ) Tj 0.952778 0 Td 54.73251 Tz (Demurtas, ) Tj 3.188889 0 Td 37.268519 Tz (J. ) Tj 51.428571 0 0 51.428571 0 295.117647 Tm 7.116667 0 Td 58.738426 Tz (Dubochet ) Tj 2.936111 0 Td 59.41358 Tz (and ) Tj 1.244444 0 Td 51.851852 Tz (H. ) Tj 0.797222 0 Td 51.311728 Tz (Vogel, ) Tj 1.983333 0 Td 60.493827 Tz (Angew. ) Tj 2.313889 0 Td 70 Tz (Chem. ) Tj 2.313889 0 Td 38.888889 Tz (Int. ) Tj 1.147222 0 Td 46.990741 Tz (Ed., ) Tj 1.283333 0 Td 53.796296 Tz (2006, ) Tj 1.769444 0 Td 49.691358 Tz (45, ) Tj 51.428571 0 0 51.428571 0 251 Tm 7.116667 0 Td 55.092593 Tz (5478-5483; ) Tj 3.519444 0 Td 44.290123 Tz (\(c\) ) Tj 0.972222 0 Td 53.472222 Tz (B. ) Tj 0.855556 0 Td 48.935185 Tz (Dubertret, ) Tj 3.111111 0 Td 38.888889 Tz (P. ) Tj 0.680556 0 Td 50.87963 Tz (Skourides, ) Tj 3.286111 0 Td 53.472222 Tz (D.J. ) Tj 1.516667 0 Td 47.222222 Tz (Norris, ) Tj 2.177778 0 Td 46.990741 Tz (V. ) Tj 48.571429 0 0 48.571429 0 212 Tm 7.514706 0 Td 56.427015 Tz (Noireaux, ) Tj 3.376471 0 Td 58.333333 Tz (A. ) Tj 1.152941 0 Td 54.901961 Tz (H. ) Tj 1.070588 0 Td 55.283224 Tz (Brivanlou ) Tj 3.335294 0 Td 64.052288 Tz (and ) Tj 1.441176 0 Td 60.04902 Tz (A. ) Tj 1.132353 0 Td 54.215686 Tz (Libchaber, ) Tj 3.644118 0 Td 52.757353 Tz (Science, ) Tj 47.142857 0 0 47.142857 0 170 Tm 7.742424 0 Td 58.686869 Tz (2002, ) Tj 1.972727 0 Td 57.449495 Tz (298, ) Tj 1.654545 0 Td 59.040404 Tz (1759-1762. ) Tj 30 0 0 30 0 883 Tm 41.6 0 Td 80.555556 Tz (50 ) Tj 30 0 0 30 0 675 Tm 41.6 0 Td 77.777778 Tz (55 ) Tj 30 0 0 30 0 467 Tm 41.633333 0 Td 77.777778 Tz (60 ) Tj 30 0 0 30 0 259 Tm 41.633333 0 Td 75 Tz (65 ) Tj 52.857143 0 0 52.857143 0 2968 Tm 32.672973 0 Td 74.099099 Tz (10 ) Tj 51.428571 0 0 51.428571 0 2914.14741 Tm 25.316667 0 Td 42.12963 Tz (5. ) Tj 0.719444 0 Td 43.209877 Tz (\(a\) ) Tj 0.972222 0 Td 66.435185 Tz (M. ) Tj 1.05 0 Td 59.953704 Tz (Kim, ) Tj 1.633333 0 Td 55.092593 Tz (K. ) Tj 0.894444 0 Td 55.092593 Tz (Sohn, ) Tj 1.886111 0 Td 53.472222 Tz (H. ) Tj 0.875 0 Td 51.851852 Tz (B. ) Tj 0.816667 0 Td 69.675926 Tz (Na ) Tj 1.030556 0 Td 58.333333 Tz (and ) Tj 1.225 0 Td 43.75 Tz (T. ) Tj 0.758333 0 Td 58.333333 Tz (Hyeon, ) Tj 2.313889 0 Td 64.00463 Tz (Nano ) Tj 1.75 0 Td 49.907407 Tz (Lett. ) Tj 51.428571 0 0 51.428571 0 2870 Tm 26.016667 0 Td 54.444444 Tz (2002, ) Tj 1.827778 0 Td 45.37037 Tz (2, ) Tj 0.816667 0 Td 55.092593 Tz (1383-1387; ) Tj 3.5 0 Td 47.530864 Tz (\(b\) ) Tj 1.05 0 Td 56.712963 Tz (K. ) Tj 0.913889 0 Td 66.435185 Tz (M. ) Tj 0.972222 0 Td 54.282407 Tz (Yeo, ) Tj 1.497222 0 Td 40.509259 Tz (J. ) Tj 0.680556 0 Td 55.902778 Tz (Shin ) Tj 1.516667 0 Td 60.493827 Tz (and ) Tj 1.302778 0 Td 32.407407 Tz (I. ) Tj 0.583333 0 Td 50.231481 Tz (S. ) Tj 0.836111 0 Td 51.041667 Tz (Lee, ) Tj 48.571429 0 0 48.571429 0 2828 Tm 27.547059 0 Td 67.254902 Tz (Chem. ) Tj 2.223529 0 Td 67.769608 Tz (Commun., ) Tj 3.458824 0 Td 57.647059 Tz (2010, ) Tj 1.914706 0 Td 53.75817 Tz (46, ) Tj 1.173529 0 Td 54.330065 Tz (64-66. ) Tj 51.428571 0 0 51.428571 0 2783.553299 Tm 25.316667 0 Td 42.12963 Tz (6. ) Tj 0.7 0 Td 43.209877 Tz (\(a\) ) Tj 0.952778 0 Td 56.712963 Tz (S.A. ) Tj 1.594444 0 Td 55.092593 Tz (Dergunov, ) Tj 3.169444 0 Td 50.231481 Tz (B. ) Tj 0.777778 0 Td 55.632716 Tz (Miksa, ) Tj 2.216667 0 Td 48.611111 Tz (B. ) Tj 0.758333 0 Td 56.712963 Tz (Ganus, ) Tj 2.255556 0 Td 45.37037 Tz (E. ) Tj 0.758333 0 Td 54.62963 Tz (Lindner ) Tj 2.411111 0 Td 59.41358 Tz (and ) Tj 1.263889 0 Td 46.990741 Tz (E. ) Tj 51.428571 0 0 51.428571 0 2739 Tm 26.036111 0 Td 50.378788 Tz (Pinkhassik, ) Tj 3.480556 0 Td 62.87037 Tz (Chem. ) Tj 2.061111 0 Td 63.599537 Tz (Commun., ) Tj 3.227778 0 Td 54.444444 Tz (2010, ) Tj 1.788889 0 Td 49.691358 Tz (46, ) Tj 1.127778 0 Td 54.12037 Tz (1485-1487; ) Tj 3.441667 0 Td 48.611111 Tz (\(b\) ) Tj 1.030556 0 Td 45.37037 Tz (S. ) Tj 51.428571 0 0 51.428571 0 2697.843707 Tm 26.036111 0 Td 59.143519 Tz (Dergunov ) Tj 3.208333 0 Td 59.41358 Tz (and ) Tj 1.419444 0 Td 48.611111 Tz (E. ) Tj 0.991667 0 Td 49.789562 Tz (Pinkhassik, ) Tj 3.616667 0 Td 59.953704 Tz (Angew. ) Tj 2.527778 0 Td 69.351852 Tz (Chem. ) Tj 2.488889 0 Td 38.888889 Tz (Int. ) Tj 1.341667 0 Td 46.180556 Tz (Ed., ) Tj 51.428571 0 0 51.428571 0 2651 Tm 26.016667 0 Td 54.444444 Tz (2008, ) Tj 1.827778 0 Td 49.691358 Tz (47, ) Tj 1.127778 0 Td 55.740741 Tz (8264-8267; ) Tj 3.558333 0 Td 45.37037 Tz (\(c\) ) Tj 1.030556 0 Td 55.902778 Tz (D.C. ) Tj 1.594444 0 Td 49.074074 Tz (Danila, ) Tj 2.313889 0 Td 48.611111 Tz (L. ) Tj 0.758333 0 Td 46.990741 Tz (T. ) Tj 0.797222 0 Td 52.777778 Tz (Banner, ) Tj 2.469444 0 Td 50.231481 Tz (E. ) Tj 0.797222 0 Td 37.268519 Tz (J. ) Tj 51.428571 0 0 51.428571 0 2609.953144 Tm 26.036111 0 Td 56.532922 Tz (Karimova, ) Tj 3.208333 0 Td 54.12037 Tz (L.Tsurkan, ) Tj 3.363889 0 Td 56.712963 Tz (X. ) Tj 0.836111 0 Td 69.675926 Tz (Wang ) Tj 1.75 0 Td 59.41358 Tz (and ) Tj 1.205556 0 Td 48.611111 Tz (E. ) Tj 0.758333 0 Td 49.789562 Tz (Pinkhassik, ) Tj 3.402778 0 Td 60.493827 Tz (Angew. ) Tj 51.428571 0 0 51.428571 0 2564 Tm 26.016667 0 Td 69.351852 Tz (Chem. ) Tj 2.275 0 Td 38.888889 Tz (Int. ) Tj 1.127778 0 Td 46.990741 Tz (Ed., ) Tj 1.244444 0 Td 55.092593 Tz (2008, ) Tj 1.788889 0 Td 55.840456 Tz (47,7036-7039; ) Tj 4.511111 0 Td 48.611111 Tz (\(d\) ) Tj 0.991667 0 Td 48.611111 Tz (S. ) Tj 0.680556 0 Td 60.493827 Tz (Tekobo ) Tj 2.294444 0 Td 59.41358 Tz (and ) Tj 1.244444 0 Td 46.990741 Tz (E. ) Tj 51.428571 0 0 51.428571 0 2520 Tm 26.036111 0 Td 50.378788 Tz (Pinkhassik, ) Tj 3.519444 0 Td 62.87037 Tz (Chem. ) Tj 2.1 0 Td 64.00463 Tz (Commun., ) Tj 3.305556 0 Td 52.5 Tz (2009, ) Tj 1.886111 0 Td 54.12037 Tz (1112-1114; ) Tj 3.480556 0 Td 44.290123 Tz (\(e\) ) Tj 0.991667 0 Td 45.37037 Tz (S. ) Tj 0.758333 0 Td 55.092593 Tz (A. ) Tj 51.428571 0 0 51.428571 0 2479.427307 Tm 26.036111 0 Td 55.452675 Tz (Dergunov, ) Tj 3.169444 0 Td 53.472222 Tz (K. ) Tj 0.816667 0 Td 50.231481 Tz (Kesterson, ) Tj 3.15 0 Td 63.194444 Tz (W. ) Tj 0.933333 0 Td 43.209877 Tz (Li, ) Tj 0.894444 0 Td 51.851852 Tz (Z. ) Tj 0.738889 0 Td 69.675926 Tz (Wang ) Tj 1.769444 0 Td 59.41358 Tz (and ) Tj 1.225 0 Td 45.37037 Tz (E. ) Tj 0.719444 0 Td 49.789562 Tz (Pinkhassik, ) Tj 51.428571 0 0 51.428571 0 2434.484211 Tm 26.016667 0 Td 55.95679 Tz (Macromolecules, ) Tj 5.308333 0 Td 53.796296 Tz (2000, ) Tj 1.866667 0 Td 50.771605 Tz (accepted: ) Tj 3.033333 0 Td 39.969136 Tz (\(f\) ) Tj 0.972222 0 Td 48.611111 Tz (L. ) Tj 0.836111 0 Td 46.990741 Tz (T. ) Tj 0.894444 0 Td 52.314815 Tz (Banner, ) Tj 2.488889 0 Td 55.092593 Tz (D.C. ) Tj 51.428571 0 0 51.428571 0 2391.838384 Tm 26.036111 0 Td 50 Tz (Danila, ) Tj 2.275 0 Td 55.452675 Tz (K.Sharpe, ) Tj 3.15 0 Td 64.814815 Tz (M. ) Tj 0.972222 0 Td 52.314815 Tz (Durkin, ) Tj 2.391667 0 Td 50.231481 Tz (B. ) Tj 0.758333 0 Td 51.446759 Tz (Clayton, ) Tj 2.663889 0 Td 48.611111 Tz (B. ) Tj 0.7 0 Td 55.812757 Tz (Anderson, ) Tj 3.130556 0 Td 55.092593 Tz (A. ) Tj 51.428571 0 0 51.428571 0 2347.649264 Tm 26.036111 0 Td 51.388889 Tz (Richter ) Tj 2.411111 0 Td 58.333333 Tz (and ) Tj 1.380556 0 Td 46.990741 Tz (E. ) Tj 0.875 0 Td 49.789562 Tz (Pinkhassik, ) Tj 3.616667 0 Td 55.452675 Tz (Langmuir, ) Tj 3.286111 0 Td 53.796296 Tz (2008, ) Tj 1.925 0 Td 48.611111 Tz (24, ) Tj 1.244444 0 Td 66.111111 Tz (11464 ) Tj 38.571429 0 0 38.571429 0 2310 Tm 34.766667 0 Td 71.296296 Tz (11473. ) Tj 51.428571 0 0 51.428571 0 2259.542416 Tm 25.297222 0 Td 43.75 Tz (7. ) Tj 0.738889 0 Td 44.290123 Tz (\(a\) ) Tj 0.952778 0 Td 56.712963 Tz (N. ) Tj 0.913889 0 Td 49.016204 Tz (Poulain, ) Tj 2.586111 0 Td 46.990741 Tz (E. ) Tj 0.758333 0 Td 56.712963 Tz (Nakache, ) Tj 2.858333 0 Td 56.712963 Tz (A. ) Tj 0.913889 0 Td 51.851852 Tz (Pina ) Tj 1.419444 0 Td 59.41358 Tz (and ) Tj 1.225 0 Td 56.712963 Tz (G. ) Tj 0.875 0 Td 37.268519 Tz (J. ) Tj 0.661111 0 Td 54.012346 Tz (Levesque, ) Tj 3.091667 0 Td 37.268519 Tz (J. ) Tj 51.428571 0 0 51.428571 0 2216.1278 Tm 26.016667 0 Td 57.79321 Tz (Polym. ) Tj 2.275 0 Td 42.777778 Tz (Sci., ) Tj 1.555556 0 Td 51.446759 Tz (1996.34, ) Tj 2.683333 0 Td 54.282407 Tz (729-737; ) Tj 2.838889 0 Td 46.450617 Tz (\(b\) ) Tj 0.991667 0 Td 40.509259 Tz (J. ) Tj 0.719444 0 Td 56.712963 Tz (Hotz ) Tj 1.575 0 Td 58.333333 Tz (and ) Tj 1.263889 0 Td 61.574074 Tz (W. ) Tj 0.972222 0 Td 51.311728 Tz (Meier, ) Tj 51.428571 0 0 51.428571 0 2172.648936 Tm 26.016667 0 Td 55.812757 Tz (Langmuir, ) Tj 3.305556 0 Td 51.203704 Tz (1998, ) Tj 1.808333 0 Td 46.450617 Tz (14, ) Tj 1.127778 0 Td 54.12037 Tz (1031-1036; ) Tj 3.480556 0 Td 45.37037 Tz (\(c\) ) Tj 0.972222 0 Td 55.092593 Tz (C. ) Tj 0.894444 0 Td 51.851852 Tz (Nardin, ) Tj 2.352778 0 Td 46.990741 Tz (T. ) Tj 0.816667 0 Td 44.074074 Tz (Hirt, ) Tj 1.516667 0 Td 37.268519 Tz (J. ) Tj 51.428571 0 0 51.428571 0 2128.555556 Tm 26.016667 0 Td 59.41358 Tz (Leukeland ) Tj 3.402778 0 Td 61.574074 Tz (W. ) Tj 0.933333 0 Td 51.851852 Tz (Meier, ) Tj 2.041667 0 Td 55.452675 Tz (Langmuir, ) Tj 3.15 0 Td 53.796296 Tz (2000, ) Tj 1.847222 0 Td 47.530864 Tz (16, ) Tj 1.069444 0 Td 54.768519 Tz (1035-1041; ) Tj 3.461111 0 Td 46.450617 Tz (\(d\) ) Tj 51.428571 0 0 51.428571 0 2084.982456 Tm 26.016667 0 Td 37.268519 Tz (J. ) Tj 0.680556 0 Td 49.151235 Tz (Kurja, ) Tj 2.022222 0 Td 48.611111 Tz (R. ) Tj 0.758333 0 Td 37.268519 Tz (J. ) Tj 0.641667 0 Td 66.435185 Tz (M. ) Tj 1.011111 0 Td 49.537037 Tz (Noelte, ) Tj 2.294444 0 Td 32.407407 Tz (I. ) Tj 0.544444 0 Td 58.333333 Tz (A. ) Tj 0.875 0 Td 61.111111 Tz (Maxwell ) Tj 2.741667 0 Td 58.333333 Tz (and ) Tj 1.186111 0 Td 56.712963 Tz (A. ) Tj 0.913889 0 Td 30.787037 Tz (I. ) Tj 0.525 0 Td 60.185185 Tz (German, ) Tj 51.428571 0 0 51.428571 0 2043.056995 Tm 26.016667 0 Td 54.282407 Tz (Polymer, ) Tj 2.858333 0 Td 51.851852 Tz (1993, ) Tj 1.730556 0 Td 50.771605 Tz (34, ) Tj 1.088889 0 Td 55.740741 Tz (2045-2049; ) Tj 3.519444 0 Td 45.37037 Tz (\(e\) ) Tj 0.972222 0 Td 51.851852 Tz (C. ) Tj 0.816667 0 Td 56.712963 Tz (A. ) Tj 0.855556 0 Td 57.973251 Tz (McKelvey, ) Tj 3.363889 0 Td 48.611111 Tz (E. ) Tj 0.758333 0 Td 63.194444 Tz (W. ) Tj 51.428571 0 0 51.428571 0 1997.720207 Tm 26.036111 0 Td 48.611111 Tz (Kaler, ) Tj 1.905556 0 Td 37.268519 Tz (J. ) Tj 0.583333 0 Td 56.712963 Tz (A. ) Tj 0.875 0 Td 50.501543 Tz (Zasadzinski, ) Tj 3.830556 0 Td 51.851852 Tz (B. ) Tj 0.797222 0 Td 55.555556 Tz (Coldren ) Tj 2.469444 0 Td 60.493827 Tz (and ) Tj 1.283333 0 Td 53.472222 Tz (H. ) Tj 0.777778 0 Td 48.611111 Tz (T. ) Tj 0.738889 0 Td 51.203704 Tz (Jung, ) Tj 1.769444 0 Td 70.486111 Tz (Lang ) Tj 51.428571 0 0 51.428571 0 1953.818653 Tm 26.016667 0 Td 51.203704 Tz (muir, ) Tj 1.672222 0 Td 53.796296 Tz (2000, ) Tj 1.847222 0 Td 55.34188 Tz (16,8285-8290; ) Tj 4.472222 0 Td 39.969136 Tz (\(f\) ) Tj 0.875 0 Td 68.055556 Tz (M. ) Tj 0.952778 0 Td 51.203704 Tz (Jung, ) Tj 1.730556 0 Td 55.092593 Tz (D. ) Tj 0.855556 0 Td 55.092593 Tz (H. ) Tj 0.816667 0 Td 63.194444 Tz (W. ) Tj 0.952778 0 Td 53.472222 Tz (Huber, ) Tj 2.080556 0 Td 38.888889 Tz (P. ) Tj 51.428571 0 0 51.428571 0 1912.496774 Tm 26.016667 0 Td 58.333333 Tz (H. ) Tj 0.875 0 Td 55.092593 Tz (H. ) Tj 0.816667 0 Td 60.185185 Tz (Bomans, ) Tj 2.683333 0 Td 37.268519 Tz (P. ) Tj 0.602778 0 Td 66.435185 Tz (M. ) Tj 0.991667 0 Td 47.530864 Tz (Frederic, ) Tj 2.683333 0 Td 38.888889 Tz (J. ) Tj 0.602778 0 Td 52.211934 Tz (Meuldijk, ) Tj 2.936111 0 Td 56.712963 Tz (A. ) Tj 0.816667 0 Td 66.435185 Tz (M. ) Tj 0.952778 0 Td 57.253086 Tz (van ) Tj 1.186111 0 Td 52.5 Tz (Herk, ) Tj 51.428571 0 0 51.428571 0 1871.655914 Tm 26.036111 0 Td 55.092593 Tz (H. ) Tj 0.952778 0 Td 50.925926 Tz (Fischer ) Tj 2.294444 0 Td 61.574074 Tz (and ) Tj 1.244444 0 Td 56.712963 Tz (A. ) Tj 0.952778 0 Td 30.787037 Tz (I. ) Tj 0.622222 0 Td 59.722222 Tz (German, ) Tj 2.761111 0 Td 55.452675 Tz (Langmuir, ) Tj 3.266667 0 Td 51.851852 Tz (1997, ) Tj 1.886111 0 Td 44.290123 Tz (13, ) Tj 1.088889 0 Td 68.865741 Tz (6877 ) Tj 51.428571 0 0 51.428571 0 1828.462988 Tm 26.036111 0 Td 53.796296 Tz (6880; ) Tj 1.827778 0 Td 46.450617 Tz (\(g\) ) Tj 0.972222 0 Td 38.888889 Tz (J. ) Tj 0.661111 0 Td 40.509259 Tz (F. ) Tj 0.719444 0 Td 37.268519 Tz (P. ) Tj 0.641667 0 Td 42.12963 Tz (d. ) Tj 0.7 0 Td 46.990741 Tz (S. ) Tj 0.738889 0 Td 62.114198 Tz (Gomes, ) Tj 2.372222 0 Td 56.712963 Tz (A. ) Tj 0.913889 0 Td 40.185185 Tz (F.-P. ) Tj 1.419444 0 Td 55.555556 Tz (Sonnen, ) Tj 2.469444 0 Td 56.712963 Tz (A. ) Tj 0.894444 0 Td 66.435185 Tz (Kronen ) Tj 51.428571 0 0 51.428571 0 1788.083333 Tm 25.997222 0 Td 48.148148 Tz (berger, ) Tj 2.158333 0 Td 37.268519 Tz (J. ) Tj 0.641667 0 Td 42.669753 Tz (Fritz, ) Tj 1.711111 0 Td 64.814815 Tz (M. ) Tj 0.933333 0 Td 53.472222 Tz (A. ) Tj 0.836111 0 Td 56.712963 Tz (N. ) Tj 0.855556 0 Td 53.703704 Tz (Coelho, ) Tj 2.45 0 Td 55.092593 Tz (D. ) Tj 0.875 0 Td 47.890947 Tz (Fournier, ) Tj 2.761111 0 Td 51.851852 Tz (C. ) Tj 0.836111 0 Td 56.30787 Tz (Fournier ) Tj 51.428571 0 0 51.428571 0 1746.595828 Tm 26.016667 0 Td 53.148148 Tz (Noel, ) Tj 1.847222 0 Td 66.435185 Tz (M. ) Tj 1.069444 0 Td 63.734568 Tz (Mauzac ) Tj 2.527778 0 Td 59.41358 Tz (and ) Tj 1.302778 0 Td 66.435185 Tz (M. ) Tj 1.069444 0 Td 48.361823 Tz (Winterhalter, ) Tj 4.063889 0 Td 55.092593 Tz (Langmuir, ) Tj 3.227778 0 Td 53.796296 Tz (2006, ) Tj 47.142857 0 0 47.142857 0 1705 Tm 28.381818 0 Td 55.387205 Tz (22, ) Tj 1.187879 0 Td 60.454545 Tz (7755-7759. ) Tj 51.428571 0 0 51.428571 0 1662 Tm 25.316667 0 Td 42.12963 Tz (8. ) Tj 0.661111 0 Td 44.290123 Tz (\(a\) ) Tj 0.952778 0 Td 40.509259 Tz (P. ) Tj 0.680556 0 Td 69.675926 Tz (He ) Tj 0.933333 0 Td 60.493827 Tz (and ) Tj 1.225 0 Td 58.333333 Tz (X. ) Tj 0.855556 0 Td 55.902778 Tz (Zhu, ) Tj 1.497222 0 Td 51.851852 Tz (Mater. ) Tj 2.022222 0 Td 51.851852 Tz (Res. ) Tj 1.419444 0 Td 43.75 Tz (Bull., ) Tj 1.730556 0 Td 53.796296 Tz (2008, ) Tj 1.769444 0 Td 55.681818 Tz (43,625-630; ) Tj 52.857143 0 0 52.857143 0 1621.52982 Tm 25.332432 0 Td 46.246246 Tz (\(b\) ) Tj 1.097297 0 Td 52.027027 Tz (K. ) Tj 0.927027 0 Td 56.756757 Tz (Hong, ) Tj 2.005405 0 Td 50.45045 Tz (D. ) Tj 0.851351 0 Td 47.647648 Tz (S.Friend, ) Tj 2.837838 0 Td 52.027027 Tz (C. ) Tj 0.87027 0 Td 56.756757 Tz (G. ) Tj 0.927027 0 Td 57.387387 Tz (Glabe ) Tj 1.948649 0 Td 56.756757 Tz (and ) Tj 1.286486 0 Td 53.603604 Tz (D. ) Tj 0.908108 0 Td 62.162162 Tz (Papahad ) Tj 51.428571 0 0 51.428571 0 1580.65679 Tm 25.977778 0 Td 50.05144 Tz (jopoulos, ) Tj 2.897222 0 Td 54.6875 Tz (Biochim. ) Tj 2.838889 0 Td 52.662037 Tz (Biophys. ) Tj 2.644444 0 Td 51.203704 Tz (Acta, ) Tj 1.75 0 Td 51.851852 Tz (1983, ) Tj 1.691667 0 Td 55.632716 Tz (732,320-323; ) Tj 4.161111 0 Td 44.290123 Tz (\(c\) ) Tj 51.428571 0 0 51.428571 0 1538.540027 Tm 26.016667 0 Td 50.231481 Tz (V. ) Tj 0.855556 0 Td 38.888889 Tz (P. ) Tj 0.719444 0 Td 47.314815 Tz (Torchilin, ) Tj 3.111111 0 Td 49.421296 Tz (Nat. ) Tj 1.497222 0 Td 51.851852 Tz (Rev. ) Tj 1.516667 0 Td 62.384259 Tz (Drug ) Tj 1.75 0 Td 50.87963 Tz (Discovery, ) Tj 3.305556 0 Td 53.796296 Tz (2005, ) Tj 1.866667 0 Td 45.37037 Tz (4, ) Tj 0.836111 0 Td 71.296296 Tz (145 ) Tj 38.571429 0 0 38.571429 0 1502 Tm 34.766667 0 Td 65.895062 Tz (16O. ) Tj 51.428571 0 0 51.428571 0 1453 Tm 25.316667 0 Td 42.12963 Tz (9. ) Tj 0.719444 0 Td 43.209877 Tz (\(a\) ) Tj 0.991667 0 Td 55.092593 Tz (H. ) Tj 0.894444 0 Td 55.740741 Tz (Hada, ) Tj 1.788889 0 Td 48.611111 Tz (Y. ) Tj 0.738889 0 Td 57.973251 Tz (Yonezawa, ) Tj 3.286111 0 Td 55.092593 Tz (A. ) Tj 0.816667 0 Td 55.092593 Tz (Yoshida ) Tj 2.508333 0 Td 58.333333 Tz (and ) Tj 1.186111 0 Td 56.712963 Tz (A. ) Tj 0.913889 0 Td 54.73251 Tz (Kurakake, ) Tj 3.130556 0 Td 37.268519 Tz (J. ) Tj 51.428571 0 0 51.428571 0 1411.827586 Tm 26.016667 0 Td 52.5 Tz (Phys. ) Tj 1.788889 0 Td 58.333333 Tz (Chem., ) Tj 2.352778 0 Td 52.5 Tz (1976, ) Tj 1.769444 0 Td 57.086895 Tz (80,2728-2731; ) Tj 4.647222 0 Td 48.611111 Tz (\(b\) ) Tj 1.05 0 Td 66.435185 Tz (M. ) Tj 1.030556 0 Td 56.532922 Tz (Sakamoto, ) Tj 3.286111 0 Td 66.435185 Tz (M. ) Tj 51.428571 0 0 51.428571 0 1372.840108 Tm 26.036111 0 Td 49.691358 Tz (Fujistuka ) Tj 3.013889 0 Td 58.333333 Tz (and ) Tj 1.322222 0 Td 46.990741 Tz (T. ) Tj 0.933333 0 Td 57.407407 Tz (Majima, ) Tj 2.722222 0 Td 37.268519 Tz (J. ) Tj 0.816667 0 Td 56.712963 Tz (Photochem. ) Tj 3.752778 0 Td 52.5 Tz (Photobiol. ) Tj 3.5 0 Td 53.472222 Tz (C. ) Tj 51.428571 0 0 51.428571 0 1328 Tm 26.016667 0 Td 54.444444 Tz (2009, ) Tj 1.847222 0 Td 52.932099 Tz (10,33-56; ) Tj 3.033333 0 Td 45.37037 Tz (\(c\) ) Tj 0.933333 0 Td 48.611111 Tz (S. ) Tj 0.758333 0 Td 56.712963 Tz (K. ) Tj 0.836111 0 Td 57.253086 Tz (Ghosh, ) Tj 2.216667 0 Td 46.990741 Tz (S. ) Tj 0.719444 0 Td 59.953704 Tz (Kundu, ) Tj 2.313889 0 Td 66.435185 Tz (M. ) Tj 0.952778 0 Td 56.944444 Tz (Mandal, ) Tj 2.547222 0 Td 46.990741 Tz (S. ) Tj 51.428571 0 0 51.428571 0 1288.516005 Tm 25.997222 0 Td 59.143519 Tz (Nath ) Tj 1.575 0 Td 58.333333 Tz (and ) Tj 1.166667 0 Td 46.990741 Tz (T. ) Tj 0.738889 0 Td 45.37037 Tz (Pal, ) Tj 1.244444 0 Td 37.268519 Tz (J. ) Tj 0.602778 0 Td 53.292181 Tz (Nanopart. ) Tj 3.052778 0 Td 47.962963 Tz (Res., ) Tj 1.594444 0 Td 53.796296 Tz (2003, ) Tj 1.769444 0 Td 55.092593 Tz (5,577-587; ) Tj 3.480556 0 Td 45.37037 Tz (\(d\) ) Tj 0.952778 0 Td 46.990741 Tz (T. ) Tj 51.428571 0 0 51.428571 0 1247.971114 Tm 26.036111 0 Td 46.180556 Tz (Itakura, ) Tj 2.547222 0 Td 53.472222 Tz (K. ) Tj 0.894444 0 Td 54.166667 Tz (Torigoe ) Tj 2.527778 0 Td 58.333333 Tz (and ) Tj 1.380556 0 Td 51.851852 Tz (K. ) Tj 0.991667 0 Td 55.092593 Tz (Esumi, ) Tj 2.313889 0 Td 55.092593 Tz (Langmuir, ) Tj 3.325 0 Td 51.851852 Tz (1995, ) Tj 1.905556 0 Td 45.37037 Tz (11, ) Tj 51.428571 0 0 51.428571 0 1206.013405 Tm 26.016667 0 Td 55.416667 Tz (4129-4134; ) Tj 3.655556 0 Td 44.290123 Tz (\(e\) ) Tj 1.05 0 Td 68.055556 Tz (M. ) Tj 1.108333 0 Td 57.744108 Tz (Sangermano, ) Tj 4.044444 0 Td 46.990741 Tz (Y. ) Tj 0.816667 0 Td 55.092593 Tz (Yagci ) Tj 1.905556 0 Td 59.41358 Tz (and ) Tj 1.322222 0 Td 58.333333 Tz (G. ) Tj 1.05 0 Td 49.151235 Tz (Rizza, ) Tj 48.571429 0 0 48.571429 0 1164 Tm 27.547059 0 Td 59.248366 Tz (Macromolecules, ) Tj 5.497059 0 Td 58.333333 Tz (2007, ) Tj 1.935294 0 Td 60.180995 Tz (40,8827-8829: ) Tj 51.428571 0 0 51.428571 0 1120 Tm 25.316667 0 Td 38.888889 Tz (\(f\) ) Tj 1.011111 0 Td 53.472222 Tz (K. ) Tj 0.991667 0 Td 55.632716 Tz (Esumi, ) Tj 2.236111 0 Td 46.990741 Tz (T. ) Tj 0.894444 0 Td 57.685185 Tz (Matsumoto, ) Tj 3.694444 0 Td 48.611111 Tz (Y. ) Tj 0.894444 0 Td 52.662037 Tz (Seto ) Tj 1.555556 0 Td 58.333333 Tz (and ) Tj 1.302778 0 Td 45.37037 Tz (T. ) Tj 0.797222 0 Td 55.092593 Tz (Yoshimura, ) Tj 3.597222 0 Td 37.268519 Tz (J. ) Tj 48.571429 0 0 48.571429 0 1081 Tm 27.547059 0 Td 55.392157 Tz (Colloid ) Tj 2.532353 0 Td 50.326797 Tz (Interface ) Tj 2.902941 0 Td 45.294118 Tz (Sci., ) Tj 1.564706 0 Td 57.647059 Tz (2005, ) Tj 1.914706 0 Td 55.759804 Tz (284, ) Tj 1.585294 0 Td 56.188725 Tz (199-203. ) Tj 51.428571 0 0 51.428571 0 1037 Tm 25.375 0 Td 44.290123 Tz (10. ) Tj 1.011111 0 Td 43.209877 Tz (\(a\) ) Tj 0.952778 0 Td 55.092593 Tz (P-L. ) Tj 1.555556 0 Td 65.895062 Tz (Kuo ) Tj 1.322222 0 Td 59.41358 Tz (and ) Tj 1.225 0 Td 56.712963 Tz (N. ) Tj 0.855556 0 Td 37.268519 Tz (J. ) Tj 0.602778 0 Td 50.231481 Tz (Turro, ) Tj 2.002778 0 Td 55.524691 Tz (Macromolecules, ) Tj 5.230556 0 Td 51.851852 Tz (1987, ) Tj 1.730556 0 Td 48.611111 Tz (20, ) Tj 51.428571 0 0 51.428571 0 996 Tm 26.094444 0 Td 54.12037 Tz (1216-1221; ) Tj 3.441667 0 Td 48.611111 Tz (\(b\) ) Tj 1.05 0 Td 50.231481 Tz (R. ) Tj 0.797222 0 Td 54.282407 Tz (Schmidt, ) Tj 2.741667 0 Td 46.990741 Tz (T. ) Tj 0.758333 0 Td 55.740741 Tz (Zhao, ) Tj 1.847222 0 Td 44.722222 Tz (J.-B. ) Tj 1.516667 0 Td 59.62963 Tz (Green ) Tj 1.963889 0 Td 58.333333 Tz (and ) Tj 1.244444 0 Td 53.472222 Tz (D. ) Tj 0.836111 0 Td 37.268519 Tz (J. ) Tj 51.428571 0 0 51.428571 0 957.577358 Tm 26.016667 0 Td 53.796296 Tz (Dyer, ) Tj 1.808333 0 Td 55.452675 Tz (Langmuir, ) Tj 3.169444 0 Td 55.092593 Tz (2002, ) Tj 1.925 0 Td 45.37037 Tz (18, ) Tj 1.088889 0 Td 53.796296 Tz (1281-1287. ) Tj 51.428571 0 0 51.428571 0 912.965309 Tm 25.355556 0 Td 46.450617 Tz (11. ) Tj 0.991667 0 Td 56.712963 Tz (A. ) Tj 0.933333 0 Td 46.990741 Tz (L. ) Tj 0.777778 0 Td 47.314815 Tz (Patterson, ) Tj 3.072222 0 Td 51.851852 Tz (Phys. ) Tj 1.769444 0 Td 47.962963 Tz (Rev., ) Tj 1.711111 0 Td 51.203704 Tz (1939, ) Tj 1.769444 0 Td 48.611111 Tz (56, ) Tj 1.069444 0 Td 53.472222 Tz (978-982. ) Tj 51.428571 0 0 51.428571 0 871.914894 Tm 25.375 0 Td 44.290123 Tz (12. ) Tj 1.030556 0 Td 37.268519 Tz (J. ) Tj 0.661111 0 Td 55.740741 Tz (Yang, ) Tj 1.886111 0 Td 53.796296 Tz (C.-H. ) Tj 1.886111 0 Td 51.041667 Tz (Lee, ) Tj 1.516667 0 Td 44.722222 Tz (H.-J. ) Tj 1.633333 0 Td 56.17284 Tz (Ko, ) Tj 1.244444 0 Td 42.12963 Tz (J.-S. ) Tj 1.536111 0 Td 53.472222 Tz (Suh, ) Tj 1.536111 0 Td 53.796296 Tz (H.-G. ) Tj 1.827778 0 Td 56.388889 Tz (Yoon, ) Tj 1.944444 0 Td 55.092593 Tz (K. ) Tj 51.428571 0 0 51.428571 0 830.253147 Tm 26.036111 0 Td 51.851852 Tz (Lee, ) Tj 1.477778 0 Td 55.740741 Tz (Y.-M. ) Tj 2.022222 0 Td 65.895062 Tz (Huh ) Tj 1.477778 0 Td 59.41358 Tz (and ) Tj 1.380556 0 Td 45.37037 Tz (S. ) Tj 0.875 0 Td 62.87037 Tz (Haam, ) Tj 2.158333 0 Td 60.493827 Tz (Angew. ) Tj 2.488889 0 Td 69.351852 Tz (Chem. ) Tj 2.430556 0 Td 38.888889 Tz (Int. ) Tj 1.283333 0 Td 46.180556 Tz (Ed., ) Tj 47.142857 0 0 47.142857 0 790 Tm 28.381818 0 Td 59.393939 Tz (2007, ) Tj 1.993939 0 Td 61.460761 Tz (46,8836-8839. ) Tj 51.428571 0 0 51.428571 0 746 Tm 25.375 0 Td 44.290123 Tz (13. ) Tj 1.05 0 Td 45.37037 Tz (\(a\) ) Tj 1.030556 0 Td 55.092593 Tz (X. ) Tj 0.972222 0 Td 52.932099 Tz (Liu ) Tj 1.186111 0 Td 59.41358 Tz (and ) Tj 1.244444 0 Td 56.712963 Tz (A. ) Tj 0.972222 0 Td 53.148148 Tz (Basu, ) Tj 1.827778 0 Td 35.648148 Tz (J. ) Tj 0.641667 0 Td 69.135802 Tz (Am. ) Tj 1.477778 0 Td 64.166667 Tz (Chem. ) Tj 2.158333 0 Td 48.611111 Tz (Soc., ) Tj 1.711111 0 Td 53.148148 Tz (2009, ) Tj 1.925 0 Td 48.611111 Tz (131, ) Tj 51.428571 0 0 51.428571 0 707.562025 Tm 26.036111 0 Td 55.092593 Tz (5718-5719; ) Tj 3.461111 0 Td 47.530864 Tz (\(b\) ) Tj 0.952778 0 Td 40.509259 Tz (J. ) Tj 0.661111 0 Td 56.388889 Tz (Deng, ) Tj 1.769444 0 Td 55.092593 Tz (Y.Yu, ) Tj 1.769444 0 Td 50.231481 Tz (S. ) Tj 0.758333 0 Td 68.055556 Tz (Dun ) Tj 1.322222 0 Td 61.574074 Tz (and ) Tj 1.186111 0 Td 63.194444 Tz (W. ) Tj 0.855556 0 Td 55.092593 Tz (Yang, ) Tj 1.788889 0 Td 37.268519 Tz (J. ) Tj 0.602778 0 Td 52.5 Tz (Phys. ) Tj 51.428571 0 0 51.428571 0 663.868874 Tm 26.016667 0 Td 63.518519 Tz (Chem. ) Tj 2.158333 0 Td 51.851852 Tz (B, ) Tj 0.797222 0 Td 54.444444 Tz (2010, ) Tj 1.886111 0 Td 50.231481 Tz (114, ) Tj 1.4 0 Td 55.740741 Tz (2593-2601; ) Tj 3.538889 0 Td 45.37037 Tz (\(c\) ) Tj 0.991667 0 Td 58.333333 Tz (X. ) Tj 0.933333 0 Td 53.148148 Tz (Feng, ) Tj 1.769444 0 Td 55.092593 Tz (C. ) Tj 0.855556 0 Td 63.194444 Tz (Mao, ) Tj 1.711111 0 Td 56.712963 Tz (G. ) Tj 51.428571 0 0 51.428571 0 623.616011 Tm 26.016667 0 Td 56.388889 Tz (Yang, ) Tj 1.925 0 Td 63.194444 Tz (W. ) Tj 1.05 0 Td 68.055556 Tz (Hou ) Tj 1.477778 0 Td 58.333333 Tz (and ) Tj 1.283333 0 Td 37.592593 Tz (J.-J. ) Tj 1.438889 0 Td 55.092593 Tz (Zhu, ) Tj 1.594444 0 Td 55.452675 Tz (Langmuir, ) Tj 3.266667 0 Td 53.796296 Tz (2006, ) Tj 1.866667 0 Td 48.611111 Tz (22, ) Tj 1.166667 0 Td 69.675926 Tz (4384 ) Tj 38.571429 0 0 38.571429 0 588 Tm 34.688889 0 Td 59.773663 Tz (4.389. ) Tj 51.428571 0 0 51.428571 0 538 Tm 25.375 0 Td 44.290123 Tz (14. ) Tj 1.030556 0 Td 44.290123 Tz (\(a\) ) Tj 0.972222 0 Td 55.092593 Tz (D. ) Tj 0.875 0 Td 59.722222 Tz (Graham, ) Tj 2.722222 0 Td 55.092593 Tz (K. ) Tj 0.894444 0 Td 51.851852 Tz (Faulds ) Tj 2.061111 0 Td 58.333333 Tz (and ) Tj 1.205556 0 Td 64.814815 Tz (W. ) Tj 1.030556 0 Td 45.37037 Tz (E. ) Tj 0.758333 0 Td 52.932099 Tz (Smith, ) Tj 2.080556 0 Td 63.518519 Tz (Chem. ) Tj 2.1 0 Td 91.820988 Tz (Com ) Tj 51.428571 0 0 51.428571 0 497 Tm 26.016667 0 Td 55.092593 Tz (mun., ) Tj 1.808333 0 Td 55.092593 Tz (2006, ) Tj 1.808333 0 Td 55.740741 Tz (4363-4371; ) Tj 3.538889 0 Td 45.37037 Tz (\(b\) ) Tj 1.011111 0 Td 66.435185 Tz (M. ) Tj 0.952778 0 Td 51.419753 Tz (Sanles-Sobrido, ) Tj 4.802778 0 Td 63.194444 Tz (W. ) Tj 0.952778 0 Td 51.311728 Tz (Exner, ) Tj 51.428571 0 0 51.428571 0 461.566845 Tm 26.036111 0 Td 48.611111 Tz (L. ) Tj 1.030556 0 Td 53.832305 Tz (Rodriguez-Lorenzo, ) Tj 6.261111 0 Td 48.611111 Tz (B. ) Tj 1.030556 0 Td 53.72807 Tz (Rodriguez-Gonzalez, ) Tj 6.552778 0 Td 64.814815 Tz (M. ) Tj 1.166667 0 Td 55.092593 Tz (A. ) Tj 48.571429 0 0 48.571429 0 416 Tm 27.547059 0 Td 55.147059 Tz (Correa-Duarte, ) Tj 4.9 0 Td 53.186275 Tz (R. ) Tj 0.864706 0 Td 58.333333 Tz (A. ) Tj 0.905882 0 Td 56.617647 Tz (Alvarez-Puebla ) Tj 4.961765 0 Td 62.908497 Tz (and ) Tj 1.358824 0 Td 49.754902 Tz (L. ) Tj 0.864706 0 Td 68.627451 Tz (M. ) Tj 1.111765 0 Td 65.686275 Tz (Liz-Mar ) Tj 48.571429 0 0 48.571429 0 374 Tm 27.547059 0 Td 51.470588 Tz (Zan, ) Tj 1.461765 0 Td 41.176471 Tz (J. ) Tj 0.638235 0 Td 74.346405 Tz (Am. ) Tj 1.564706 0 Td 66.568627 Tz (Chem. ) Tj 2.223529 0 Td 50.784314 Tz (Soc., ) Tj 1.708824 0 Td 56.960784 Tz (2009, ) Tj 1.997059 0 Td 53.186275 Tz (131, ) Tj 1.461765 0 Td 58.676471 Tz (2699-2705. ) Tj 38.571429 0 0 38.571429 0 301 Tm 40.107407 0 Td 106.296296 Tz (OTHER ) Tj 3.448148 0 Td 107.239057 Tz (EMBODIMENTS ) Tj 51.428571 0 0 51.428571 0 214.815013 Tm 26.036111 0 Td 64.00463 Tz (From ) Tj 1.847222 0 Td 50.771605 Tz (the ) Tj 1.166667 0 Td 52.211934 Tz (foregoing ) Tj 3.111111 0 Td 46.990741 Tz (description, ) Tj 3.694444 0 Td 32.407407 Tz (it ) Tj 0.680556 0 Td 46.180556 Tz (will ) Tj 1.380556 0 Td 58.333333 Tz (be ) Tj 0.952778 0 Td 52.662037 Tz (apparent ) Tj 2.780556 0 Td 46.990741 Tz (that ) Tj 51.428571 0 0 51.428571 0 168.631579 Tm 25.297222 0 Td 47.314815 Tz (variations ) Tj 3.072222 0 Td 59.41358 Tz (and ) Tj 1.322222 0 Td 50.605413 Tz (modifications ) Tj 4.2 0 Td 68.055556 Tz (may ) Tj 1.477778 0 Td 58.333333 Tz (be ) Tj 0.972222 0 Td 64.00463 Tz (made ) Tj 1.75 0 Td 48.611111 Tz (to ) Tj 0.816667 0 Td 50.771605 Tz (the ) Tj 1.166667 0 Td 50.05144 Tz (invention ) Tj ET Q endstream 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41.206395 Tz (in ) Tj 0.69593 0 Td 51.889535 Tz (a ) Tj 0.512791 0 Td 54.94186 Tz (polymer ) Tj 2.472384 0 Td 59.738372 Tz (nanocap ) Tj 53.015873 0 0 53.015873 0 1472.669196 Tm 6.167964 0 Td 42.754491 Tz (Sule, ) Tj 1.471257 0 Td 50.748503 Tz (prepare ) Tj 2.301198 0 Td 51.696607 Tz (according ) Tj 2.961377 0 Td 45.583832 Tz (to ) Tj 0.716766 0 Td 49.251497 Tz (the ) Tj 1.07515 0 Td 58.682635 Tz (method ) Tj 2.282335 0 Td 55.01497 Tz (of ) Tj 0.754491 0 Td 50.928144 Tz (claim ) Tj 1.754192 0 Td 40.868263 Tz (1. ) Tj 30 0 0 30 0 2547 Tm 41.666667 0 Td 75 Tz (10 ) Tj 30 0 0 30 0 2339 Tm 41.633333 0 Td 75 Tz (15 ) Tj 30 0 0 30 0 1923 Tm 41.566667 0 Td 80.555556 Tz (25 ) Tj 30 0 0 30 0 1716 Tm 41.6 0 Td 80.555556 Tz (30 ) Tj 51.428571 0 0 51.428571 0 2969 Tm 33.6 0 Td 72.916667 Tz (12 ) Tj 54.444444 0 0 54.444444 0 2916.782101 Tm 24.593878 0 Td 46.938776 Tz (10. ) Tj 1.010204 0 Td 61.22449 Tz (The ) Tj 1.304082 0 Td 49.591837 Tz (metal ) Tj 1.744898 0 Td 46.428571 Tz (nanoparticle ) Tj 3.526531 0 Td 50.680272 Tz (entrapped ) Tj 2.957143 0 Td 41.326531 Tz (in ) Tj 0.697959 0 Td 48.979592 Tz (a ) Tj 0.495918 0 Td 55.539359 Tz (polymer ) Tj 2.534694 0 Td 63.520408 Tz (nano ) Tj 54.545455 0 0 54.545455 0 2875.78202 Tm 23.851667 0 Td 49.325397 Tz (capsule ) Tj 2.2 0 Td 55 Tz (of ) Tj 0.733333 0 Td 50.111111 Tz (claim ) Tj 1.65 0 Td 44.305556 Tz (9, ) Tj 0.696667 0 Td 52.380952 Tz (wherein ) Tj 2.365 0 Td 46.851852 Tz (the ) Tj 1.026667 0 Td 49.5 Tz (metal ) Tj 1.686667 0 Td 46.597222 Tz (nanoparticle ) Tj 3.538333 0 Td 35.138889 Tz (is ) Tj 0.568333 0 Td 51.944444 Tz (a ) Tj 0.495 0 Td 50.111111 Tz (metal ) Tj 54.444444 0 0 54.444444 0 2837.353865 Tm 23.895918 0 Td 46.30102 Tz (Selected ) Tj 2.369388 0 Td 55.102041 Tz (from ) Tj 1.487755 0 Td 46.938776 Tz (the ) Tj 1.010204 0 Td 52.653061 Tz (group ) Tj 1.781633 0 Td 46.530612 Tz (consisting ) Tj 2.938776 0 Td 53.571429 Tz (of ) Tj 0.716327 0 Td 39.358601 Tz (silver, ) Tj 1.855102 0 Td 47.619048 Tz (platinum, ) Tj 2.755102 0 Td 52.653061 Tz (palla ) Tj 51.904762 0 0 51.904762 0 2797.803738 Tm 25.045872 0 Td 54.587156 Tz (dium, ) Tj 1.849541 0 Td 57.798165 Tz (and ) Tj 1.213761 0 Td 48.165138 Tz (gold. ) Tj 54.444444 0 0 54.444444 0 2758.75323 Tm 24.612245 0 Td 45.918367 Tz (11. ) Tj 0.991837 0 Td 61.22449 Tz (The ) Tj 1.304082 0 Td 50.816327 Tz (metal ) Tj 1.744898 0 Td 46.428571 Tz (nanoparticle ) Tj 3.544898 0 Td 50.340136 Tz (entrapped ) Tj 2.938776 0 Td 42.857143 Tz (in ) Tj 0.697959 0 Td 52.040816 Tz (a ) Tj 0.514286 0 Td 55.539359 Tz (polymer ) Tj 2.516327 0 Td 64.285714 Tz (nano ) Tj 54.571429 0 0 54.571429 0 2717.764059 Tm 23.840314 0 Td 49.30192 Tz (capsule ) Tj 2.235602 0 Td 51.919721 Tz (of ) Tj 0.696335 0 Td 50.08726 Tz (claim ) Tj 1.722513 0 Td 43.775451 Tz (10, ) Tj 0.989529 0 Td 52.356021 Tz (wherein ) Tj 2.34555 0 Td 46.829552 Tz (the ) Tj 1.007853 0 Td 50.08726 Tz (metal ) Tj 1.704188 0 Td 46.829552 Tz (nanoparticle ) Tj 3.518325 0 Td 36.649215 Tz (is ) Tj 0.586387 0 Td 39.267016 Tz (silver. ) Tj 54.444444 0 0 54.444444 0 2679.758085 Tm 24.612245 0 Td 45.918367 Tz (12. ) Tj 0.991837 0 Td 61.22449 Tz (The ) Tj 1.304082 0 Td 50.816327 Tz (metal ) Tj 1.744898 0 Td 46.428571 Tz (nanoparticle ) Tj 3.544898 0 Td 50.340136 Tz (entrapped ) Tj 2.938776 0 Td 42.857143 Tz (in ) Tj 0.697959 0 Td 52.040816 Tz (a ) Tj 0.514286 0 Td 55.539359 Tz (polymer ) Tj 2.516327 0 Td 63.520408 Tz (nano ) Tj 54.571429 0 0 54.571429 0 2640.126615 Tm 23.840314 0 Td 49.30192 Tz (capsule ) Tj 2.308901 0 Td 54.973822 Tz (of ) Tj 0.842932 0 Td 49.47644 Tz (claim ) Tj 1.740838 0 Td 44.284468 Tz (9, ) Tj 0.824607 0 Td 51.919721 Tz (wherein ) Tj 2.437173 0 Td 46.829552 Tz (the ) Tj 1.081152 0 Td 55.410122 Tz (polymer ) Tj 2.602094 0 Td 50.809139 Tz (nanocapsule ) Tj 3.628272 0 Td 35.122164 Tz (is ) Tj 0.696335 0 Td 51.919721 Tz (a ) Tj 52.857143 0 0 52.857143 0 2603.154093 Tm 24.613514 0 Td 56.756757 Tz (copolymer ) Tj 3.197297 0 Td 56.756757 Tz (of ) Tj 0.756757 0 Td 56.756757 Tz (a ) Tj 0.52973 0 Td 48.198198 Tz (styrene ) Tj 2.213514 0 Td 51.238739 Tz (with ) Tj 1.418919 0 Td 49.399399 Tz (divinylbenzene. ) Tj 54.444444 0 0 54.444444 0 2561.777202 Tm 24.612245 0 Td 45.918367 Tz (13. ) Tj 0.991837 0 Td 61.22449 Tz (The ) Tj 1.304082 0 Td 49.591837 Tz (metal ) Tj 1.744898 0 Td 46.428571 Tz (nanoparticle ) Tj 3.526531 0 Td 50.680272 Tz (entrapped ) Tj 2.957143 0 Td 42.857143 Tz (in ) Tj 0.697959 0 Td 52.040816 Tz (a ) Tj 0.495918 0 Td 55.539359 Tz (polymer ) Tj 2.534694 0 Td 63.520408 Tz (nano ) Tj 54.571429 0 0 54.571429 0 2521.045455 Tm 23.840314 0 Td 49.30192 Tz (capsule ) Tj 2.290576 0 Td 53.446771 Tz (of ) Tj 0.769634 0 Td 49.47644 Tz (claim ) Tj 1.777487 0 Td 45.811518 Tz (12, ) Tj 1.062827 0 Td 51.919721 Tz (wherein ) Tj 2.400524 0 Td 47.847586 Tz (the ) Tj 1.044503 0 Td 55.410122 Tz (polymer ) Tj 2.54712 0 Td 51.086784 Tz (nanocapsule ) Tj 3.591623 0 Td 36.649215 Tz (is ) Tj 0.67801 0 Td 51.919721 Tz (a ) Tj 54.571429 0 0 54.571429 0 2484.64603 Tm 23.840314 0 Td 54.973822 Tz (copolymer ) Tj 3.096859 0 Td 54.973822 Tz (of ) Tj 0.769634 0 Td 44.194641 Tz (tert-butylstyrene ) Tj 4.672775 0 Td 49.629145 Tz (with ) Tj 1.410995 0 Td 47.643979 Tz (divinylbenzene. ) Tj 54.603175 0 0 54.603175 0 2444.054254 Tm 24.522384 0 Td 44.767442 Tz (14. ) Tj 0.934012 0 Td 76.30814 Tz (A ) Tj 0.567733 0 Td 43.87718 Tz (catalyst ) Tj 2.197674 0 Td 51.27907 Tz (comprising ) Tj 3.15 0 Td 57.994186 Tz (a ) Tj 0.476163 0 Td 49.447674 Tz (metal ) Tj 1.611628 0 Td 47.056686 Tz (nanoparticle ) Tj 3.479651 0 Td 49.854651 Tz (entrapped ) Tj 2.820349 0 Td 41.206395 Tz (in ) Tj 53.061224 0 0 53.061224 0 2405.439024 Tm 24.518846 0 Td 50.25641 Tz (a ) Tj 0.471154 0 Td 56.987179 Tz (polymer ) Tj 2.563077 0 Td 52.540793 Tz (nanocapsule ) Tj 3.637308 0 Td 51.652422 Tz (according ) Tj 2.94 0 Td 47.115385 Tz (to ) Tj 0.753846 0 Td 50.884615 Tz (claim ) Tj 1.696154 0 Td 45.544872 Tz (9. ) Tj 53.174603 0 0 53.174603 0 2364.046599 Tm 25.181194 0 Td 48.059701 Tz (15. ) Tj 0.996716 0 Td 81.492537 Tz (A ) Tj 0.639403 0 Td 50.149254 Tz (sensor ) Tj 1.955821 0 Td 52.656716 Tz (comprising ) Tj 3.272239 0 Td 56.41791 Tz (a ) Tj 0.507761 0 Td 50.776119 Tz (metal ) Tj 1.730149 0 Td 48.059701 Tz (nanoparticle ) Tj 3.59194 0 Td 51.542289 Tz (entrapped ) Tj 2.952537 0 Td 42.313433 Tz (in ) Tj 53.061224 0 0 53.061224 0 2324.441558 Tm 24.5 0 Td 53.397436 Tz (a ) Tj 0.49 0 Td 56.987179 Tz (polymer ) Tj 2.544231 0 Td 52.540793 Tz (nanocapsule ) Tj 3.637308 0 Td 52.001425 Tz (according ) Tj 2.958846 0 Td 45.544872 Tz (to ) Tj 0.735 0 Td 50.884615 Tz (claim ) Tj 1.715 0 Td 45.544872 Tz (9. ) Tj 54.603175 0 0 54.603175 0 2279.96802 Tm 24.540698 0 Td 45.784884 Tz (16. ) Tj 0.934012 0 Td 76.30814 Tz (A ) Tj 0.60436 0 Td 56.468023 Tz (method ) Tj 2.124419 0 Td 53.415698 Tz (of ) Tj 0.714244 0 Td 51.27907 Tz (performing ) Tj 3.15 0 Td 54.94186 Tz (a ) Tj 0.457849 0 Td 48.023256 Tz (metal-catalyzed ) Tj 4.450291 0 Td 43.410853 Tz (reaction, ) Tj 2.472384 0 Td 47.819767 Tz (the ) Tj 53.015873 0 0 53.015873 0 2239.067237 Tm 24.53982 0 Td 58.682635 Tz (method ) Tj 2.32006 0 Td 52.814371 Tz (comprising ) Tj 3.31976 0 Td 49.670659 Tz (contacting ) Tj 3.131138 0 Td 53.443114 Tz (a ) Tj 0.509281 0 Td 46.36976 Tz (reactant ) Tj 2.414371 0 Td 50.299401 Tz (with ) Tj 1.395808 0 Td 50.299401 Tz (a ) Tj 0.509281 0 Td 51.556886 Tz (metal ) Tj 1.773054 0 Td 65.232036 Tz (nano ) Tj 54.642857 0 0 54.642857 0 2200.15995 Tm 23.80915 0 Td 43.082789 Tz (particle ) Tj 2.324183 0 Td 50.157347 Tz (entrapped ) Tj 2.983007 0 Td 42.701525 Tz (in ) Tj 0.805229 0 Td 51.851852 Tz (a ) Tj 0.585621 0 Td 55.337691 Tz (polymer ) Tj 2.598693 0 Td 50.742721 Tz (nanocapsule ) Tj 3.605229 0 Td 50.835149 Tz (according ) Tj 3.001307 0 Td 42.701525 Tz (to ) Tj 40 0 0 40 0 2160 Tm 32.525 0 Td 68.333333 Tz (claim ) Tj 2.25 0 Td 60.416667 Tz (9. ) Tj 54.603175 0 0 54.603175 0 2114.782554 Tm 24.540698 0 Td 45.784884 Tz (17. ) Tj 0.97064 0 Td 79.360465 Tz (A ) Tj 0.677616 0 Td 55.959302 Tz (method ) Tj 2.17936 0 Td 53.415698 Tz (of ) Tj 0.714244 0 Td 49.176357 Tz (preparing ) Tj 2.802035 0 Td 48.837209 Tz (a ) Tj 0.476163 0 Td 50.05814 Tz (metal ) Tj 1.684884 0 Td 46.802326 Tz (nanoparticle ) Tj 3.534593 0 Td 50.193798 Tz (entrapped ) Tj 54.693878 0 0 54.693878 0 2073.173352 Tm 23.78694 0 Td 42.661692 Tz (in ) Tj 0.694776 0 Td 48.756219 Tz (a ) Tj 0.45709 0 Td 55.721393 Tz (polymer ) Tj 2.486567 0 Td 49.010158 Tz (nanocapsule, ) Tj 3.711567 0 Td 46.72471 Tz (the ) Tj 1.042164 0 Td 56.374378 Tz (method ) Tj 2.19403 0 Td 48.756219 Tz (comprising: ) Tj 53.265306 0 0 53.265306 0 2033.103535 Tm 25.100766 0 Td 51.106854 Tz (providing ) Tj 2.94751 0 Td 53.192848 Tz (an ) Tj 0.863602 0 Td 54.980843 Tz (aqueous ) Tj 2.534483 0 Td 53.192848 Tz (phase ) Tj 1.802299 0 Td 49.438059 Tz (containing ) Tj 3.191571 0 Td 43.805875 Tz (vesicles, ) Tj 2.609579 0 Td 53.192848 Tz (wherein ) Tj 53.142857 0 0 53.142857 0 1988.240964 Tm 25.873656 0 Td 49.133811 Tz (the ) Tj 1.016129 0 Td 55.107527 Tz (aqueous ) Tj 2.465054 0 Td 54.569892 Tz (phase ) Tj 1.806452 0 Td 47.827061 Tz (includes ) Tj 2.465054 0 Td 53.315412 Tz (a ) Tj 0.489247 0 Td 51.433692 Tz (metal ) Tj 1.731183 0 Td 39.986559 Tz (salt ) Tj 1.129032 0 Td 56.451613 Tz (and ) Tj 1.166667 0 Td 48.088411 Tz (the ) Tj 1.016129 0 Td 46.258961 Tz (vesicles ) Tj 51.428571 0 0 51.428571 0 1946.925703 Tm 26.755556 0 Td 55.497685 Tz (comprise ) Tj 2.819444 0 Td 46.990741 Tz (at ) Tj 0.738889 0 Td 44.722222 Tz (least ) Tj 1.497222 0 Td 59.41358 Tz (one ) Tj 1.244444 0 Td 61.574074 Tz (monomer; ) Tj 3.15 0 Td 60.493827 Tz (and ) Tj 54.428571 0 0 54.428571 0 1904.924084 Tm 24.564304 0 Td 51.290464 Tz (polymerizing ) Tj 3.895013 0 Td 46.952464 Tz (the ) Tj 1.010499 0 Td 42.869641 Tz (at ) Tj 0.716535 0 Td 42.257218 Tz (least ) Tj 1.451444 0 Td 55.11811 Tz (one ) Tj 1.212598 0 Td 62.554681 Tz (monomer ) Tj 2.811024 0 Td 42.869641 Tz (to ) Tj 0.734908 0 Td 53.587052 Tz (form ) Tj 1.524934 0 Td 46.952464 Tz (the ) Tj 1.028871 0 Td 60.476815 Tz (poly ) Tj 53.265306 0 0 53.265306 0 1865.344031 Tm 25.814176 0 Td 62.579821 Tz (mer ) Tj 1.276628 0 Td 52.623941 Tz (nanocapsule ) Tj 3.585824 0 Td 58.407833 Tz (and ) Tj 1.182759 0 Td 50.957854 Tz (simultaneously ) Tj 4.430651 0 Td 54.533844 Tz (forming ) Tj 2.421839 0 Td 47.977863 Tz (the ) Tj 1.032567 0 Td 51.315453 Tz (metal ) Tj 54.761905 0 0 54.761905 0 1825.931224 Tm 25.126957 0 Td 46.92029 Tz (nanoparticle ) Tj 3.56087 0 Td 50.048309 Tz (entrapped ) Tj 2.885217 0 Td 41.086957 Tz (in ) Tj 0.657391 0 Td 47.681159 Tz (the ) Tj 1.004348 0 Td 55.652174 Tz (polymer ) Tj 2.501739 0 Td 48.695652 Tz (nanocapsule. ) Tj 50.25974 0 0 50.25974 0 1779.907143 Tm 26.641602 0 Td 50.846971 Tz (18. ) Tj 1.213695 0 Td 66.322136 Tz (The ) Tj 1.551938 0 Td 61.90066 Tz (method ) Tj 2.526873 0 Td 61.347976 Tz (of ) Tj 0.974935 0 Td 53.72093 Tz (claim ) Tj 1.989664 0 Td 49.741602 Tz (17, ) Tj 1.253488 0 Td 56.847545 Tz (wherein ) Tj 2.72584 0 Td 50.846971 Tz (the ) Tj 1.233592 0 Td 48.083549 Tz (at ) Tj 0.895349 0 Td 45.762274 Tz (least ) Tj 1.671318 0 Td 60.795291 Tz (one ) Tj 54.428571 0 0 54.428571 0 1739.444727 Tm 23.902887 0 Td 63.429571 Tz (monomer ) Tj 2.811024 0 Td 38.276465 Tz (is ) Tj 0.624672 0 Td 52.055993 Tz (polymerized ) Tj 3.619423 0 Td 44.4007 Tz (in ) Tj 0.698163 0 Td 52.055993 Tz (a ) Tj 0.47769 0 Td 42.257218 Tz (lipid ) Tj 1.414698 0 Td 46.369204 Tz (bilayer ) Tj 2.094488 0 Td 56.649169 Tz (of ) Tj 0.753281 0 Td 46.952464 Tz (the ) Tj 1.010499 0 Td 42.869641 Tz (vesicles. ) Tj 54.52381 0 0 54.52381 0 1695.74934 Tm 24.558079 0 Td 45.851528 Tz (19. ) Tj 1.008734 0 Td 59.097525 Tz (The ) Tj 1.247162 0 Td 57.05968 Tz (method ) Tj 2.219214 0 Td 53.49345 Tz (of ) Tj 0.733624 0 Td 50.131004 Tz (claim ) Tj 1.742358 0 Td 43.813683 Tz (18, ) Tj 1.008734 0 Td 52.401747 Tz (wherein ) Tj 2.365939 0 Td 46.870451 Tz (the ) Tj 1.027074 0 Td 41.572052 Tz (lipid ) Tj 1.393886 0 Td 46.28821 Tz (bilayer ) Tj 2.09083 0 Td 39.737991 Tz (is ) Tj 0.623581 0 Td 51.965066 Tz (a ) Tj 53.142857 0 0 53.142857 0 1659.312668 Tm 24.481183 0 Td 43.27957 Tz (lipid ) Tj 1.467742 0 Td 47.043011 Tz (bilayer ) Tj 2.126344 0 Td 56.451613 Tz (of ) Tj 0.771505 0 Td 50.179211 Tz (a ) Tj 0.489247 0 Td 50.527678 Tz (liposome. ) Tj 54.428571 0 0 54.428571 0 1611.368283 Tm 24.582677 0 Td 47.97317 Tz (20. ) Tj 1.047244 0 Td 60.221639 Tz (The ) Tj 1.304462 0 Td 57.159522 Tz (method ) Tj 2.24147 0 Td 56.649169 Tz (of ) Tj 0.771654 0 Td 50.831146 Tz (claim ) Tj 1.782152 0 Td 45.931759 Tz (16, ) Tj 1.047244 0 Td 52.493438 Tz (wherein ) Tj 2.425197 0 Td 46.952464 Tz (the ) Tj 1.028871 0 Td 50.831146 Tz (metal ) Tj 1.76378 0 Td 57.305337 Tz (nanopar ) Tj 52.857143 0 0 52.857143 0 1569.359236 Tm 24.594595 0 Td 41.621622 Tz (ticle ) Tj 1.456757 0 Td 37.837838 Tz (is ) Tj 0.681081 0 Td 57.282282 Tz (formed ) Tj 2.27027 0 Td 58.333333 Tz (by ) Tj 0.927027 0 Td 45.195195 Tz (free-radical ) Tj 3.5 0 Td 48.698699 Tz (reduction ) Tj 2.837838 0 Td 58.333333 Tz (of ) Tj 0.832432 0 Td 50.45045 Tz (a ) Tj 0.52973 0 Td 52.342342 Tz (metal ) Tj 1.816216 0 Td 48.348348 Tz (ion ) Tj 1.097297 0 Td 58.858859 Tz (dis ) Tj 53.095238 0 0 53.095238 0 1530.995876 Tm 24.521973 0 Td 50.224215 Tz (Solved ) Tj 1.977578 0 Td 45.515695 Tz (in ) Tj 0.715695 0 Td 56.502242 Tz (an ) Tj 0.866368 0 Td 54.70852 Tz (aqueous ) Tj 2.504933 0 Td 47.982063 Tz (solvent ) Tj 2.147085 0 Td 49.701046 Tz (phase. ) Tj 24 0 0 24 0 1482 Tm 67.916667 0 Td 52.083333 Tz (ck ) Tj 2.333333 0 Td 52.083333 Tz (ck ) Tj 2.375 0 Td 52.083333 Tz (ck ) Tj 2.333333 0 Td 52.083333 Tz (ck ) Tj 2.375 0 Td 48.611111 Tz (ck ) Tj ET Q endstream endobj xref 3 1 0000923174 00000 n 17 1 0000923481 00000 n 31 1 0000923792 00000 n 45 1 0000924103 00000 n 59 1 0000924414 00000 n 73 1 0000924725 00000 n 87 1 0000925036 00000 n 101 1 0000925347 00000 n 115 1 0000925663 00000 n 129 1 0000925979 00000 n 144 20 0000926295 00000 n 0000926348 00000 n 0000943899 00000 n 0000943952 00000 n 0000944875 00000 n 0000944928 00000 n 0000945794 00000 n 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